*  Lancet
T-CELL-RECEPTOR β-CHAIN GENE REARRANGEMENTS 1985 * POSSIBLE RISK OF STEROID ADMINISTRATION IN PATIENTS AT RISK FOR AIDS 1985 ... ASSOCIATION BETWEEN POLYARTERITIS AND AUSTRALIA ANTIGEN. 296:1149-53. 1970 * Anaphylactic reaction to A.L.G. after induction of ... Intrathecal beta-endorphin 1980 * Aetiological implications of sex ratio in glomerulonephritis. 1979 ... Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open ...
  http://vivo.med.cornell.edu/display/journal0140-6736
*  NUCLEIC ACID PACKAGING SYSTEM - Patent application
The ompK gene of V. parahaemolyticus encodes the outer membrane protein (OMP) that has been identified as the host receptor for ... A low copy origin of replication may be used to maintain the cloned DNA in a host cell while also minimizing rearrangements. A ... Amplifying the nucleic acid may be accomplished by using the polymerase chain reaction. The sequencing reaction may be a ... However, non-covalent linkages, such as chelation or antigen-antibody complexes, may also be used to join the oligonucleotide ...
  http://www.patentsencyclopedia.com/app/20100304445
*  The Fish Molecular Genetics and Biotechnology Laboratory: Publications
Importance of CArG boxes in regulation of the carp beta-actin gene expression. Gene 108:211-216. ... Identification, phylogeny and expression of retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs), Developmental and ... Molecular characterization of an immobilization antigen gene of the fish-parasite protozoan Ichthiophthirius multifiliis strain ... 2001). Detection of Yersinia ruckeri in rainbow trout blood by use of polymerase chain reaction. Disease of Aquatic Organisms ...
  http://www.auburn.edu/academic/agriculture/fisheries/genomics/publications.html
*  Integrin Targeted Therapeutics
... specific lymphocyte homing receptor as an integrin molecule with an alpha chain homologous to human VLA-4 alpha. Cell. 1989;56: ... Effect of a very late antigen-4 receptor antagonist on allergen-induced airway responses and inflammation in asthma. Clin Exp ... Crystal structure of the complete integrin αvβ3 ectodomain plus an alpha/beta transmembrane fragment. J Cell Biol. 2009;186:589 ... 5. Legate K, Wickström S, Fässler R. Genetic and cell biological analysis of integrin outside-in signaling. Genes Dev. 2009;23: ...
  http://thno.org/v01p0154.htm
*  Methods for detecting Hepatitis C virus using polynucleotides specific for same - Chiron Corporation
Krissansen, et al., "Primary Structure of the T3 K Subunit of the T3/T Cell Antigen Receptor Complex Deduced From Cdna ... Gibson, et al., "Homology Between Two EBV Early Genes and HSV Ribonucleotide Reductase and 38K Genes," Nucleic Acids Res. 12(12 ... b) providing a set of primer oligonucleotides which are printers for the polymerase chain reaction method and which flank the ... The above study will detect insertions or deletions as small as approximately 20NT to 50NT and DNA rearrangements altering the ...
  http://www.freepatentsonline.com/5712088.html
*  Bertil Glader | Stanford Medicine Profiles
... of the immunoglobulin heavy chain and kappa light chain genes as well as the gene for the beta chain of the T-cell receptor ( ... and the immunoglobulin gene rearrangement studies showed rearranged heavy chain genes with germ line light chain genes. ... each cell line showed some minor changes in antigen expression or enzyme level. Antigen loss, de novo antigen expression, or ... rearrangements of chromosome 14 have been observed with a break in the band that contains the alpha chain gene for the T cell ...
  https://med.stanford.edu/profiles/bertil-glader
*  Method for treating a metastatic carcinoma using a conditionally lethal gene - Patent # 5997859 - PatentGenius
... construct which directs the expression of a gene product (e.g., HSVTK) that activates a compound with little or no cytotoxicity ... Anderson et al., "A conserved sequence in the T-cell receptor .beta.-chain promoter region," Proc. Natl. Acad. Sci. USA 85: ... subunit of the human and mouse CD3/T-cell antigen receptor complexes," Immunogenetics 26: 258-266, 1987... Ledley, "Somatic ... 1. Adenoviruses offer certain advantages over retroviruses,including no rearrangement of intron-containing genes or inhibition ...
  http://www.patentgenius.com/patent/5997859.html
*  MONOCLONAL ANTIBODIES AGAINST HEPATITIS C VIRUS CORE PROTEIN - Patent application
... heavy chain variable domain and a light chain variable domain with a total of 6 CDRs involved in antigen binding per antigen ... Biological properties include but are not limited to binding receptor; induction of cell proliferation, inhibiting cell growth ... For example, the technology for expression of both heavy and light chain genes in E. coli is the subject of the PCT patent ... an anti-lymphotoxin beta receptor (LTBR) antibody being developed by Biogen, CAT-152, an anti-TGF-β2 antibody being developed ...
  http://www.patentsencyclopedia.com/app/20120009196
*  Items where Faculty or Department is "Faculty of Infectious and Tropical Diseases | Dept of Pathogen Molecular Biology" - LSHTM...
A complete view of the genetic diversity of the Escherichia coli O-antigen biosynthesis gene cluster. DNA research. ISSN 1340- ... Killer-cell immunoglobulin-like receptors and falciparum malaria in southwest Nigeria. Human immunology. ISSN 0198-8859 DOI: ... Generation of antigenic diversity in Plasmodium falciparum by structured rearrangement of Var genes during mitosis. PLoS ... Sepúlveda, N; Manjurano, A; Drakeley, C; Clark, TG; (2014) On the Performance of Multiple Imputation Based on Chained Equations ...
  http://researchonline.lshtm.ac.uk/view/divisions/ITPM/2014.html
*  Antibody - wikidoc
B cell, NK cell, Mast cell, Basophil, Eosinophil) • Phagocyte (Neutrophil, Macrophage, Dendritic cell) • Antigen-presenting ... one D and one J gene segment (or one V and one J segment in the light chain). As there are multiple copies of each type of gene ... and a membrane-bound form attached to the surface of a B cell that is called the B cell receptor (BCR). The BCR allows a B cell ... "Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions". Proc. Natl. Acad. Sci. U. ...
  http://ec2-184-73-211-184.compute-1.amazonaws.com/index.php/Immunoglobulin
*  Roeland Nusse | Stanford Medicine Profiles
... mediated by Frizzled molecules that act as Wnt receptors on the cell surface. In the genome of Drosophila, seven Wnt genes ( ... fluorescence microscopy and immunohistochemistry was used to confirm colocalization of beta-catenin with the oval cell antigen ... The rearrangements all appeared to be due to the insertion of an MMTV provirus, and the integration sites were located in at ... for histologic analysis and determination of Wnt family gene expression by quantitative reverse transcription-polymerase chain ...
  https://med.stanford.edu/profiles/roeland-nusse
*  Differential Requirement of Histone Acetylase and Deacetylase Activities for IRF5-Mediated Proinflammatory Cytokine Expression ...
Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature 434: 243-249. ... Induction of CD4+ T Cell Apoptosis as a Consequence of Impaired Cytoskeletal Rearrangement in UVB-Irradiated Dendritic Cells ... Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor ... Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A ...
  http://www.jimmunol.org/content/185/10/6003.full
*  Spontaneous Organ-Specific Th2-Mediated Autoimmunity in TCR Transgenic Mice | The Journal of Immunology
The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-αβ-transgenic model. J. Exp. Med. ... Structures of junctional regions of TXA51 TCR α- and β-chains. V-, D-, and J-gene assignments were made using IMGT/V-QUEST ... Induction of CD4+ T Cell Apoptosis as a Consequence of Impaired Cytoskeletal Rearrangement in UVB-Irradiated Dendritic Cells ... Cultures were then harvested and counted in a beta spectrometer. ... Mouse T-cell receptor variable gene segment families. ...
  http://www.jimmunol.org/content/172/5/2917.long
*  Protocols and Video Articles Authored by Javier D. Murillo
Oct, 2011 , Pubmed ID: 21807569 Variation in the beta-1 and beta-2 adrenergic receptor genes (ADRB1 and ADRB2, respectively) ... One of the IgMs was also expressed as a hexamer without J chain. Clones with cell specific productivities greater than 20 pg/ ... Ex vivo analyses to determine the identity of the draining lymph node cell type responsible for tumor antigen cross- ... The nucleotide and D-alanine binding pockets are flexible, requiring significant structural rearrangement of the bordering ...
  https://www.jove.com/author/Javier+D._Murillo
*  The molecular biology of acute promyelocytic leukemia | Springer for Research & Development
Activation of retinoid X receptors induces apoptosis in HL-60 cell lines. Mol Cell Biol 15:3540-3551.PubMedGoogle Scholar ... Retinoic acid receptor alpha (RARα)-region mutations in the PML-RARα fusion gene of acute promyelocytic leukemia (APL) patients ... Identification of DNA rearrangements at the retinoic acid receptor alpha (RAR-alpha) locus in all patients with acute ... differentiation is impaired in transgenic mice with targeted expression of a dominant negative form of retinoid X receptor beta ...
  https://rd.springer.com/chapter/10.1007/978-0-585-38571-6_4
*  Griffith Harsh, MD | Stanford Medicine Profiles
GBM cell lines were more adherent to OPN-R and OPN-L than OPN-FL. Adhesion to OPN altered gene expression, in particular genes ... Cells formed cytospheres that resembled neurospheres when seeded into stem cell media and coexpressed beta-tubulin and glial ... The expression of Ang-1, Ang-2, VEGF, and Tie-2, a member of the receptor tyrosine kinases and the natural receptor for both ... associated with massive kappa light chain amyloidosis of the meninges. Extranodal MZL is a low-grade B-cell lymphoma that may ...
  https://med.stanford.edu/profiles/griffith-harsh
*  Methods for assessing Calpain 2 Resistance, Disease Progression, and Treatment Efficacy in Ovarian Cancer - Patent application
G-CSFR mRNA was elevated in chemoresistant cell lines (FIG. 33). [0191]SRB1: Also known as CLA-1, this gene encodes a receptor ... Cell-based screening assay to identify molecules that stimulate ifn-alpha/beta target genes. ... However, the gene is located on chromosome 3 at 3p21.3, a region associated with chromosomal rearrangements in ovarian cancer ( ... apoptosis and the SART3 tumor rejection antigen (Schwerk et al., 2003, Mol. Cell Biol. 23:2981-90; Harada et al., 2001, Int. J ...
  http://www.patentsencyclopedia.com/app/20100221729
*  Pediatric Posttransplant Lymphoproliferative Disease: Overview, Incidence, Risk Factors
Determination of cell surface heavy and light chain Ig expression allows for classification as polyclonal or monoclonal. ... immunoglobulin gene-rearrangement, and virologic. The classification schemes have common features, including benign hyperplasia ... Elimination of these cells is carried out by human leukocyte antigen (HLA)-restricted, EBV-specific, cytotoxic T lymphocytes. ... Polymorphisms in 2 key anti-inflammatory cytokines, IL-10 and tumor growth factor (TGF)-beta, are associated with ...
  https://emedicine.medscape.com/article/1013758-overview
*  Protocols and Video Articles Authored by Patrick Collins
... suggesting that a higher fraction of divergent genes are transcribed in a given cell than the fraction of other genes. ... We now report that B cell sequestration requires lineage-specific regulation of migratory receptors by the transcription factor ... including the ability to quickly respond to MZ-associated antigens and pathogens in a T cell-dependent manner. This work ... This implies that active Lgt4 has a much higher affinity/specificity for the beta-(1-->4)-linked Glc on the (1-->4) branch than ...
  https://www.jove.com/author/Patrick_Collins
*  Cooling Inflammation: Health Diagrams II - Curing Autoimmunity and Allergies
Antibody producing B cells are produced through a million random rearrangements of antibody genes and those B cells producing ... fragment and present the antigen fragments/peptides to activate B or T cells with corresponding receptors. The activated B ... Immune cell development in the gut is dependent on bacteria, the gut flora. Damage to the gut flora, e.g. by antibiotics, ... I am a bit confused about Short Chain Fatty acid production being stimulated by RS. Autism has recently been shown to be linked ...
  http://coolinginflammation.blogspot.com/2014/03/health-diagrams-ii-curing-autoimmunity.html?showComment=1435035429001
*  USE OF REGULATORY SEQUENCES FOR SPECIFIC, TRANSIENT EXPRESSION IN NEURONAL DETERMINED CELLS - Patent application
Only recently, first attempts for the direct isolation of NSCs by cell surface antigens or by promoter driven reporter gene ... gene, a receptor gene, an anti-apoptotic gene, a determination/differentiation gene, a gene capable of inducing and/or ... beta-galactosidase). [0063]Examples of marker or reporter genes, which allow the expression activity of regulatory sequences, ... MAP-1B promoter is expressed at high level in mature neurons undergoing synaptic rearrangement or sprouting. It is also highly ...
  http://www.patentsencyclopedia.com/app/20110020790
*  X chromosome studies and breast and ovarian carcinoma - UBC Library Open Collections
... estrogen receptor alpha estrogen receptor beta FISH FMR1 fluorescence in situ hybridization fragile mental retardation 1 gene ... X chromosome rearrangements such as mutations or deletions that interfere with the proliferative capabilities of a cell during ... 2004). Many of these overexpressed genes were found in areas of major cancer testis antigen gene clusters and 11 of the ... polymerase chain reaction premature ovarian failure progesterone receptor positive progesterone receptor negative RT-PCR ...
  https://open.library.ubc.ca/cIRcle/collections/ubctheses/24/items/1.0066174
*  Proprioceptive Sensory Neuropathy in Mice with a Mutation in the Cytoplasmic Dynein Heavy Chain 1 Gene | Journal of Neuroscience
Mutations in the neurotrophic tyrosine kinase receptor type 1 (TrkA) gene and the nerve growth factor (NGF) β gene have been ... 2004) A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception. Hum Mol Genet 13:799-805. ... 1995) Gene targeting of BPAG1: abnormalities in mechanical strength and cell migration in stratified epithelia and neurologic ... null mutations in the bullous pemphigoid antigen 1 (BPAG1) gene have been shown to result in progressive sensory neuron ...
  http://www.jneurosci.org/content/27/52/14515
*  The role of HGF/c-MET signaling pathway in lymphoma | Journal of Hematology & Oncology | Full Text
... especially B cell lymphoma, T and NK cell lymphoma, and Hodgkin lymphoma. We also discuss the existing problems and future ... the receptor tyrosine kinase (RTK) for hepatocyte growth factor (HGF), has been implicated in tumorigenesis and represented a ... Jucker M, Gunther A, Gradl G, Fonatsch C, Krueger G, Diehl V, Tesch H. The Met/hepatocyte growth factor receptor (HGFR) gene is ... c-Met is a novel tumor associated antigen for T-cell based immunotherapy against NK/T cell lymphoma. Oncoimmunology. 2015;4(2): ...
  https://jhoonline.biomedcentral.com/articles/10.1186/s13045-016-0366-y
*  KAKEN - Researchers | MIYAGI Taeko (50006110)
... cell adhesion / tumor-related antigen / NCAMポリシアル酸 / シグナル伝達 / sugar chain / 癌関連抗原 / gene / 細胞接着 / 接着 / sialic acid / sialidase ... Insulin receptor / sialidase / メラノーマ / cDNAクロ-ニング / 転写調節 / Gタンパク / ミクロドメイン / 癌糖鎖特異的モノクロン抗体 / insulin receptor substrate 1 / ... Journal Article] A strategy for constructing C-sialosides based on Ireland-Claisen rearrangement and its application for ... Contribution of sialidase NEU1 to suppression of metastasis of human colon cancer
  https://nrid.nii.ac.jp/nrid/1000050006110/