*  A potential role of probiotics in colorectal cancer prevention: review of possible mechanisms of action | SpringerLink
Nagengast F, Grubben M, van Munster I (1995) Role of bile acids in colorectal carcinogenesis. Eur J Cancer 31A:1067-1070Google ... Culpepper BST, Mai V (2013) Evidence for contributions of gut microbiota to colorectal carcinogenesis. Curr Nutr Rep 2:10-18 ... Vannucci L, Stepankova R, Kozakova H, Fiserova A, Rossmann P, Tlaskalova-Hogenova H (2008) Colorectal carcinogenesis in germ- ... synbiotic and their association on early biomarkers of rat colon carcinogenesis. Food Chem Toxicol 48:772-780Google Scholar ...
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*  Plus it
Carcinogenesis Tamoxifen-DNA Adduct Formation in Rat Liver Determined by Immunoassay and 32P-Postlabeling. Rao L. Divi, Martin ... A large body of literature supports the associations among DNA damage, mutagenesis, and carcinogenesis. The probability that a ... Abstract LB-087: A facilitative role for caspase 3 in promoting genetic instability and carcinogenesis ... 2 ⇓ . Rats were given 0, 0.5, 1.0, 5.0, 10.0, and 20.0 mg TAM/kg bw daily for 7 days and were euthanized 24 h after the last ...
  http://cancerres.aacrjournals.org/content/59/19/4829
*  Increased Number of β-Adrenoceptors in Hepatocytes from Rats Treated with 2-Acetylaminofluorene | Cancer Research
Increased Number of β-Adrenoceptors in Hepatocytes from Rats Treated with 2-Acetylaminofluorene. Magne Refsnes, Georg Sager, ... We report that hepatocytes isolated from rats which had been fed 2-AAF (0.025% w/w) for 8-12 weeks had an increased number of β ... For both ligands the number of binding sites was about 4-fold higher in hepatocytes from 2-AAF-treated rats than in those from ... 2 Research fellow of The Norwegian Cancer Society. To whom requests for reprints should be addressed. ...
  http://cancerres.aacrjournals.org/content/46/5/2285
*  Antigenotoxic and Anticarcinogenic Effects of Thiols. In Vitro Inhibition of the Mutagenicity of Drug Nitrosation Products and...
Its role in hepatocarcinogenesis, Carcinogenesis 6:165 (1985).PubMedCrossRefGoogle Scholar ... S. De Flora and A. Picciotto, Mutagenicity of cimetidine in nitrite-enriched human gastric juice, Carcinogenesis 1:925 (1980). ... S. De Flora, C. Bennicelli, A. Camoirano and P. Zanacchi, Genotoxicity of nitrosated ranitidine, Carcinogenesis 1A:255 (1983). ... "Quantitative Aspects of Risk Assessment in Chemical Carcinogenesis", J. Clemmesen, D. M. Conning and F. Oesch, eds., Springer- ...
  https://rd.springer.com/chapter/10.1007/978-1-4757-9640-7_8
*  Comparing the Frequency and Spectra of Mutations Induced When an SV40-Based Shuttle Vector Containing Covalently Bound Residues...
1.Carcinogenesis Laboratory-Fee Hall Department of Microbiology and Department of BiochemistryMichigan State UniversityEast ... Moore P., Rabkin, S. D., Osborn, A. L., King C. M., and Strauss, B. S. (1982). Effect of acetylated and deacetylated 2- ... Heflich, R. H., Djuric, Z., Zhuo, Z., Fullerton, N. F., Casciano, D. A., and Beland, F. A. (1988). Metabolism of 2- ... acetylaminofluorene in the Chinese hamster ovary cell mutation assay. Environ. Mol. Mutag. 11, 167-181.CrossRefGoogle Scholar ...
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*  Evaluation of DNA Binding In Vivo for Low-Dose Extrapolation in Chemical Carcinogenesis | SpringerLink
Lutz, W.K., and P. Maier (1988) Genotoxic and epigenetic chemical carcinogenesis: One Process, different mechanisms. Trends ... Evaluation of DNA Binding In Vivo for Low-Dose Extrapolation in Chemical Carcinogenesis. ... Evaluation of DNA Binding In Vivo for Low-Dose Extrapolation in Chemical Carcinogenesis. In: Waters M.D., Daniel F.B., Lewtas J ... In vivo covalent binding of organic chemicals to DNA as a quantitative indicator in the process of chemical carcinogenesis. ...
  https://link.springer.com/chapter/10.1007/978-1-4684-5850-3_25
*  The Role of Initiating and Promoting Properties in Aromatic Amine Carcinogenesis | Springer for Research & Development
... on mouse skin carcinogenesis, Carcinogenesis 1:271 (1980).PubMedCrossRefGoogle Scholar ... Comparison with other aromatic amines, Carcinogenesis 8:1021 (1987).PubMedCrossRefGoogle Scholar ... R. A. Andersen, M. Enomoto, E. C. Miller and J. A. Miller, Carcinogenesis and inhibition of the Walker 256 tumor in the rat by ... H.-G. Neumann, The role of DNA-damage in chemical carcinogenesis of aromatic amines, J. Cancer Res. Clin. Oncol. 112:100 (1986 ...
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*  CiNii 論文 - Role of Point Mutation of the K-ras Gene in Tumorigenesis of B6C3F 1 Mouse Lung...
K-ras mutation is an early event in pancreatic duct carcinogenesis in the Syrian golden hamster. CERNY W. L. ... An experimental analysis of cancer: role of ras oncogenes in multistep carcinogenesis SUKUMAR S. ... Carcinogenspecific mutation and amplification of Ha-ras during mouse skin carcinogenesis QUINTANILLA M. ... Oncogenes, anti-oncogenes and the molecular bases of multistep carcinogenesis WEINBERG RA. ...
  https://ci.nii.ac.jp/naid/10008069746
*  Suse Broyde
Carcinogenesis (1985 Jan) PMID: 3967335. Broyde S, Hingerty B. Studies on the conformation and dynamics of the C8-substituted ... Minor-groove binding models for acetylaminofluorene modified DNA.. J Biomol Struct Dyn (1989 Dec) PMID: 2627297. Shapiro R, ... Carcinogenesis (1996 Jan) PMID: 8565123. Nolan SJ, Vyas RR, Hingerty BE, Ellis S, Broyde S, Shapiro R, Basu AK ... Carcinogenesis (1985 May) PMID: 4006057. Broyde S, Hingerty BE, Srinivasan AR. Conformations of DNA adducts with polycyclic ...
  https://as.nyu.edu/faculty/suse-broyde.html
*  Betel Quid (IARC Summary & Evaluation, Supplement7, 1987)
... anthracene-induced mammary carcinogenesis in rats. Cancer Lett., 26, 207-214 4. IARC Monographs, Suppl. 6, 113, 1987 Last ... 2. Tanaka, T., Kuniyasu, T., Shima, H., Sugie, S., Mori, H., Takahashi, M. & Hirono, J. (1986) Carcinogenicity of betel quid. ... Enhancement of 4-nitroquinoline-1-oxide and N-2-fluorenylacetamide-induced carcinogenesis in rats by subsequent administration ... 2]. Aqueous extracts of betel leaf were tested in mice by oral intubation and by intraperitoneal injection, in hamsters by ...
  http://www.inchem.org/documents/iarc/suppl7/betelquid.html
*  CiNii 論文 - Decreased Levels of 2-Amino-3-methylimidazo[4,5-f]quinoline-DNA Adducts in Rats...
Chemoprevention of colon carcinogenesis by the natural product of a simple phenolic compound protocatechuic acid : suppressing ... Chemoprevention of mouse urinary bladder carcinogenesis by the naturally occurring carotenoid astaxanthin TANAKA T. ... Effects of α-tocopherol on carcinogenesis in various organs of rats TSUDA H. ... Inhibition of 4-nitroquinoline-1-oxide-induced rat tongue carcinogenesis by the naturally occurring plant phenolics caffeic, ...
  https://ci.nii.ac.jp/naid/10008072678
*  Lipotropic Factors and Carcinogenesis | SpringerLink
Rogers, A. E., and Newberne, P. M., 1980, Lipotrope deficiency in experimental carcinogenesis, Nutr. Cancer 2: 104-112.CrossRef ... Newberne P.M., Rogers A.E. (1991) Lipotropic Factors and Carcinogenesis. In: Alfin-Slater R.B., Kritchevsky D. (eds) Cancer and ... Shinozuka, H., Katyal, S. L., and Lombardi, B., 1978, Azaserine carcinogenesis: Organ susceptibility change in rats fed a diet ... Roebuck, B. D., Yager, J. D., and Longnecker, D. S., 1981, Dietary modulation of azaserine-induced pancreatic carcinogenesis in ...
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*  Effects of Oral Administration of N-Acetyl-l-cysteine | Cancer Epidemiology, Biomarkers & Prevention
De Flora S., Ramel C. Mechanisms of inhibitors of mutagenesis and carcinogenesis. Classification and overview. Mutat. Res., 202 ... Wilpart M., Speder A., Roberfroid M. Anti-initiation activity of N-acetylcysteine in experimental colonic carcinogenesis. ... which give rise to carcinogenesis both before and after the agent is administered. In the present study, we investigated the ... 2. Correlation between plasma cotinine levels in the NAC (r = 0.7, P = 0.009) and placebo (r = 0.7, P = 0.005) groups at time 0 ...
  http://cebp.aacrjournals.org/content/11/2/167.long
*  The Evolving Role of Drug Metabolism in Drug Discovery and Development | Springer for Research & Development
On the protective action of certain polycyclic aromatic hydrocarbons against carcinogenesis by aminoazo dyes and 2- ... acetylaminofluorene Cancer Res. 18:469-477 (1958).PubMedGoogle Scholar. *. 4.. G. C. Mueller and J. A. Miller. The metabolism ... 2.. R. I. Dorfman, J. W. Cook, and J. B. Hamilton. Conversion by the human of the testis hormone, testosterone, into the ... Absorption properties and P-glycoprotein activity of modified Caco-2 cell lines. Eur. J. Pharm. Sci. 26:266-279 (2005).PubMed ...
  https://rd.springer.com/article/10.1007/s11095-006-9217-9
*  Potentiation of growth inhibition and epigenetic modulation by combination of green tea polyphenol and 5-aza-2′-deoxycytidine...
Epigenetic therapy by DNA demethylating agent 5-aza-2′-deoxycytidine (5-aza 2′dC) is clinically effective in acute myeloid ... Carcinogenesis 32(4):537-544. doi: 10.1093/carcin/bgq285 CrossRefPubMedCentralPubMedGoogle Scholar ... Carcinogenesis 25(9):1567-1574. doi: 10.1093/carcin/bgh168 CrossRefPubMedGoogle Scholar ... Widschwendter M, Jones PA (2002) DNA methylation and breast carcinogenesis. Oncogene 21(35):5462-5482. doi: 10.1038/sj.onc. ...
  https://link.springer.com/article/10.1007%2Fs10549-015-3295-5
*  Fluoride Action Network | Fluoride's Mutagenicity: In vitro Studies
Carcinogenesis 9: 2279-84.. "Sodium fluoride was found to induce morphological transformation of SHE cells seeded on a feeder ... In contrast, four tested non-carcinogens, included 4-acetylaminofluorene, pyrene, benzylpenicillin sodium and vitamin C, were ... SOURCE: National Toxicology Program [NTP] (1990). Toxicology and Carcinogenesis Studies of Sodium Fluoride in F344/N Rats and ... as a target organ of NaF carcinogenesis.". SOURCE: Mihashi M, Tsutsui T. (1996). Clastogenic activity of sodium fluoride to rat ...
  https://fluoridealert.org/studies/cancer01/
*  8.8 Risk assessment and risk management | Free Medical Textbook
For example, the Moolgavkar-Venson-Knudson model is based on a two-stage model for carcinogenesis; two mutations are required ... Armitage and Doll (1957) developed a multistage model for carcinogenesis based on the hypothesis that a series of ordered ... National Toxicology Program(1987). Toxicology and carcinogenesis studies of ethylene oxide in B6C3F1 mice. US Department of ... Moolgavkar, S.H. and Luebeck, G.(1990). Two-event model for carcinogenesis: biological, mathematical, and statistical ...
  https://medtextfree.wordpress.com/2011/11/06/8-8-risk-assessment-and-risk-management/
*  Closing Remarks | SpringerLink
Balmain, A., 1985, Transforming ras oncogenes and multistage carcinogenesis, Brit. J. Cancer, 51: 1.PubMedCrossRefGoogle ... Pegg, A. E., 1984, Methylation of the 06 position of guanine in DNA is the most likely initiating event in carcinogenesis by ... Singer, B., 1984, Alkylation of the 06 of guanine is only one of many chemical events that may initiate carcinogenesis, Cancer ... I. Adult female CD-1 mice, Carcinogenesis (London), 5: 1613.Google Scholar ...
  https://link.springer.com/chapter/10.1007/978-1-4684-5134-4_100
*  Tryptophan Side Effects: L-Tryptophan Is Far From Harmless
Cohen SM, Arai M, Jacobs JB, Friedell GH, "Promoting effect of saccharin and DL-tryptophan in urinary bladder carcinogenesis", ... "It could be concluded that tryptophan metabolites play a complementary role in promoting carcinogenesis […]." (Chung & Gadupudi ... promoting carcinogenesis (Mezrich, et al., 2010; Chung & Gadupudi, 2011). The consumption of a supplement of tryptophan will ... 2006 Aug;318(2):604-10. Epub 2006 Apr 27.. You are here: Nutritional Supplements HOME › Tryptophan Side Effects (Supplement ...
  https://www.supplements-and-health.com/tryptophan-side-effects.html
*  KAKEN - Researchers | KASAI Shinichi (40091566)
Basic research of bone marrow cells for liver regeneration, fibrogenesis, and carcinogenesis. *. Principal Investigator. ... 1986 : 旭川医大, 医学部, 講師 Review Section/Research Field. Principal Investigator. General surgery / Agro-economics Except Principal ... 1986 - 1990 : Asahikawa Medical College, 医学部, 講師. 1989 : 旭川歯科大学, 医学部, 講師. ... 2】腫瘍 / 遺伝子導入 / 胎児肝細胞 / Electroporation / 拡
  https://nrid.nii.ac.jp/nrid/1000040091566/
*  The Etiology of Cancer: Chemical and Physical Agents
Our earliest knowledge concerning chemical carcinogenesis came from clinical observations in humans. In 1775, Percivall Pott, ... CHEMICAL CARCINOGENESIS. One hundred and forty years after Dr. Pott's report of the association of soot from the combus- tion ... acetylaminofluorene (Figure 3.3). In addition, the aromatic amines, 2-naphthylamine and benzi- dine, are carcinogenic for the ... As we learn more of the process of carcinogenesis, the term carcino- gen will be further refined in relation to general usage ...
  http://fx.damasgate.com/the-etiology-of-cancer-chemical-and-physical-agents/
*  Plus it
1991) Roles of UDP-glucuronosyltransferases in chemical carcinogenesis. CRC Crit Rev Biochem Mol Biol 26:129-150. ... 2B) and containing the entire C/EBP-like element was used in gel shift assays. A less complex pattern of bound proteins, which ... Figure 2 A, Competition gel shift assay with the region C oligomers. 32P-labeled ds oligomer probes (20,000 cpm) for each of ... 2B, the C/EBP oligonucleotide was as effective as the unlabeled C1 oligomer in competing for protein binding to the labeled C1 ...
  http://molpharm.aspetjournals.org/content/53/6/1027
*  Identification of bipotential progenitor cells in human liver development - Haruna - 2003 - Hepatology - Wiley Online Library
Cell behavior in the acetylaminofluorene-treated regenerating rat liver: light and electron microscopic observations. Am J ... Carcino-genesis 1991; 12: 225-231. *CrossRef,. *PubMed,. *CAS,. *Web of Science® Times Cited: 43 ... 2. Tseng SCG, Jarvinen MT, Nelson WG, Huang HW, Woodcock-Mitchell J, Sun TT. Correlation of specific keratins with different ...
  http://onlinelibrary.wiley.com/doi/10.1002/hep.510230312/references
*  Antibodies Specific for DNA Components Modified by Chemical Carcinogens and Their Binding Efficiency to DNA Modified in Vivo...
... detects femtomoles of acetylaminofluorene-DNA adducts, Carcinogenesis 1:455 (1980).PubMedCrossRefGoogle Scholar ... ethylnitrosourea or N-acetylaminofluorene, Carcinogenesis 6:263 (1985).PubMedCrossRefGoogle Scholar ... Implications for quantification of benzo(a)pyrene DNA adducts in vivo, Carcinogenesis 8:1263 (1987).PubMedCrossRefGoogle ... L. L. Hsieh, A. M. Jeffrey and R. M. Santella, Monoclonal antibodies to 1-aminopyrene-DNA, Carcinogenesis 6:1289 (1985).PubMed ...
  https://rd.springer.com/chapter/10.1007/978-1-4757-9640-7_13
*  ASMscience | Other Diseases Associate
de Boer, J., and, J. H. Hoeijmakers. 2000. Nucleotide excision repair and human syndromes. Carcinogenesis 21:453-460.. ... 2. Ahrens, C.,, M. Grewe,, M. Berneburg,, S. Grether-Beck,, X. Quilliet,, M. Mezzina,, A. Sarasin,, A. R. Lehmann,, C. F. ... Lambert, W. C., and, M. L. Lambert. 1985. Co-recessive inheritance: a model for DNA repair, genetic disease and carcinogenesis. ... pyrene-induced mutagenesis and carcinogenesis in repair-deficient Cockayne syndrome group B mice. Cancer Res. 60:5681-5687.. ...
  http://www.asmscience.org/content/book/10.1128/9781555816704.ch25