A potential role of probiotics in colorectal cancer prevention: review of possible mechanisms of action | SpringerLink
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Carcinogenesis Tamoxifen-DNA Adduct Formation in Rat Liver Determined by Immunoassay and 32P-Postlabeling. Rao L. Divi, Martin ... A large body of literature supports the associations among DNA damage, mutagenesis, and carcinogenesis. The probability that a ... Abstract LB-087: A facilitative role for caspase 3 in promoting genetic instability and carcinogenesis ... 2 ⇓ . Rats were given 0, 0.5, 1.0, 5.0, 10.0, and 20.0 mg TAM/kg bw daily for 7 days and were euthanized 24 h after the last ...http://cancerres.aacrjournals.org/content/59/19/4829
Increased Number of β-Adrenoceptors in Hepatocytes from Rats Treated with 2-Acetylaminofluorene | Cancer Research
Increased Number of β-Adrenoceptors in Hepatocytes from Rats Treated with 2-Acetylaminofluorene. Magne Refsnes, Georg Sager, ... We report that hepatocytes isolated from rats which had been fed 2-AAF (0.025% w/w) for 8-12 weeks had an increased number of β ... For both ligands the number of binding sites was about 4-fold higher in hepatocytes from 2-AAF-treated rats than in those from ... 2 Research fellow of The Norwegian Cancer Society. To whom requests for reprints should be addressed. ...http://cancerres.aacrjournals.org/content/46/5/2285
Antigenotoxic and Anticarcinogenic Effects of Thiols. In Vitro Inhibition of the Mutagenicity of Drug Nitrosation Products and...
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Comparing the Frequency and Spectra of Mutations Induced When an SV40-Based Shuttle Vector Containing Covalently Bound Residues...
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Evaluation of DNA Binding In Vivo for Low-Dose Extrapolation in Chemical Carcinogenesis | SpringerLink
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The Role of Initiating and Promoting Properties in Aromatic Amine Carcinogenesis | Springer for Research & Development
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CiNii 論文 - Role of Point Mutation of the K-ras Gene in Tumorigenesis of B6C3F 1 Mouse Lung...
K-ras mutation is an early event in pancreatic duct carcinogenesis in the Syrian golden hamster. CERNY W. L. ... An experimental analysis of cancer: role of ras oncogenes in multistep carcinogenesis SUKUMAR S. ... Carcinogenspecific mutation and amplification of Ha-ras during mouse skin carcinogenesis QUINTANILLA M. ... Oncogenes, anti-oncogenes and the molecular bases of multistep carcinogenesis WEINBERG RA. ...https://ci.nii.ac.jp/naid/10008069746
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Betel Quid (IARC Summary & Evaluation, Supplement7, 1987)
... anthracene-induced mammary carcinogenesis in rats. Cancer Lett., 26, 207-214 4. IARC Monographs, Suppl. 6, 113, 1987 Last ... 2. Tanaka, T., Kuniyasu, T., Shima, H., Sugie, S., Mori, H., Takahashi, M. & Hirono, J. (1986) Carcinogenicity of betel quid. ... Enhancement of 4-nitroquinoline-1-oxide and N-2-fluorenylacetamide-induced carcinogenesis in rats by subsequent administration ... 2]. Aqueous extracts of betel leaf were tested in mice by oral intubation and by intraperitoneal injection, in hamsters by ...http://www.inchem.org/documents/iarc/suppl7/betelquid.html
CiNii 論文 - Decreased Levels of 2-Amino-3-methylimidazo[4,5-f]quinoline-DNA Adducts in Rats...
Chemoprevention of colon carcinogenesis by the natural product of a simple phenolic compound protocatechuic acid : suppressing ... Chemoprevention of mouse urinary bladder carcinogenesis by the naturally occurring carotenoid astaxanthin TANAKA T. ... Effects of α-tocopherol on carcinogenesis in various organs of rats TSUDA H. ... Inhibition of 4-nitroquinoline-1-oxide-induced rat tongue carcinogenesis by the naturally occurring plant phenolics caffeic, ...https://ci.nii.ac.jp/naid/10008072678
Lipotropic Factors and Carcinogenesis | SpringerLink
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Effects of Oral Administration of N-Acetyl-l-cysteine | Cancer Epidemiology, Biomarkers & Prevention
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The Evolving Role of Drug Metabolism in Drug Discovery and Development | Springer for Research & Development
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Potentiation of growth inhibition and epigenetic modulation by combination of green tea polyphenol and 5-aza-2′-deoxycytidine...
Epigenetic therapy by DNA demethylating agent 5-aza-2′-deoxycytidine (5-aza 2′dC) is clinically effective in acute myeloid ... Carcinogenesis 32(4):537-544. doi: 10.1093/carcin/bgq285 CrossRefPubMedCentralPubMedGoogle Scholar ... Carcinogenesis 25(9):1567-1574. doi: 10.1093/carcin/bgh168 CrossRefPubMedGoogle Scholar ... Widschwendter M, Jones PA (2002) DNA methylation and breast carcinogenesis. Oncogene 21(35):5462-5482. doi: 10.1038/sj.onc. ...https://link.springer.com/article/10.1007%2Fs10549-015-3295-5
Fluoride Action Network | Fluoride's Mutagenicity: In vitro Studies
Carcinogenesis 9: 2279-84.. "Sodium fluoride was found to induce morphological transformation of SHE cells seeded on a feeder ... In contrast, four tested non-carcinogens, included 4-acetylaminofluorene, pyrene, benzylpenicillin sodium and vitamin C, were ... SOURCE: National Toxicology Program [NTP] (1990). Toxicology and Carcinogenesis Studies of Sodium Fluoride in F344/N Rats and ... as a target organ of NaF carcinogenesis.". SOURCE: Mihashi M, Tsutsui T. (1996). Clastogenic activity of sodium fluoride to rat ...https://fluoridealert.org/studies/cancer01/
8.8 Risk assessment and risk management | Free Medical Textbook
For example, the Moolgavkar-Venson-Knudson model is based on a two-stage model for carcinogenesis; two mutations are required ... Armitage and Doll (1957) developed a multistage model for carcinogenesis based on the hypothesis that a series of ordered ... National Toxicology Program(1987). Toxicology and carcinogenesis studies of ethylene oxide in B6C3F1 mice. US Department of ... Moolgavkar, S.H. and Luebeck, G.(1990). Two-event model for carcinogenesis: biological, mathematical, and statistical ...https://medtextfree.wordpress.com/2011/11/06/8-8-risk-assessment-and-risk-management/
Closing Remarks | SpringerLink
Balmain, A., 1985, Transforming ras oncogenes and multistage carcinogenesis, Brit. J. Cancer, 51: 1.PubMedCrossRefGoogle ... Pegg, A. E., 1984, Methylation of the 06 position of guanine in DNA is the most likely initiating event in carcinogenesis by ... Singer, B., 1984, Alkylation of the 06 of guanine is only one of many chemical events that may initiate carcinogenesis, Cancer ... I. Adult female CD-1 mice, Carcinogenesis (London), 5: 1613.Google Scholar ...https://link.springer.com/chapter/10.1007/978-1-4684-5134-4_100
Tryptophan Side Effects: L-Tryptophan Is Far From Harmless
Cohen SM, Arai M, Jacobs JB, Friedell GH, "Promoting effect of saccharin and DL-tryptophan in urinary bladder carcinogenesis", ... "It could be concluded that tryptophan metabolites play a complementary role in promoting carcinogenesis […]." (Chung & Gadupudi ... promoting carcinogenesis (Mezrich, et al., 2010; Chung & Gadupudi, 2011). The consumption of a supplement of tryptophan will ... 2006 Aug;318(2):604-10. Epub 2006 Apr 27.. You are here: Nutritional Supplements HOME › Tryptophan Side Effects (Supplement ...https://www.supplements-and-health.com/tryptophan-side-effects.html
KAKEN - Researchers | KASAI Shinichi (40091566)
Basic research of bone marrow cells for liver regeneration, fibrogenesis, and carcinogenesis. *. Principal Investigator. ... 1986 : 旭川医大, 医学部, 講師 Review Section/Research Field. Principal Investigator. General surgery / Agro-economics Except Principal ... 1986 - 1990 : Asahikawa Medical College, 医学部, 講師. 1989 : 旭川歯科大学, 医学部, 講師. ... 2】腫瘍 / 遺伝子導入 / 胎児肝細胞 / Electroporation / 拡https://nrid.nii.ac.jp/nrid/1000040091566/
The Etiology of Cancer: Chemical and Physical Agents
Our earliest knowledge concerning chemical carcinogenesis came from clinical observations in humans. In 1775, Percivall Pott, ... CHEMICAL CARCINOGENESIS. One hundred and forty years after Dr. Pott's report of the association of soot from the combus- tion ... acetylaminofluorene (Figure 3.3). In addition, the aromatic amines, 2-naphthylamine and benzi- dine, are carcinogenic for the ... As we learn more of the process of carcinogenesis, the term carcino- gen will be further refined in relation to general usage ...http://fx.damasgate.com/the-etiology-of-cancer-chemical-and-physical-agents/
1991) Roles of UDP-glucuronosyltransferases in chemical carcinogenesis. CRC Crit Rev Biochem Mol Biol 26:129-150. ... 2B) and containing the entire C/EBP-like element was used in gel shift assays. A less complex pattern of bound proteins, which ... Figure 2 A, Competition gel shift assay with the region C oligomers. 32P-labeled ds oligomer probes (20,000 cpm) for each of ... 2B, the C/EBP oligonucleotide was as effective as the unlabeled C1 oligomer in competing for protein binding to the labeled C1 ...http://molpharm.aspetjournals.org/content/53/6/1027
Identification of bipotential progenitor cells in human liver development - Haruna - 2003 - Hepatology - Wiley Online Library
Cell behavior in the acetylaminofluorene-treated regenerating rat liver: light and electron microscopic observations. Am J ... Carcino-genesis 1991; 12: 225-231. *CrossRef,. *PubMed,. *CAS,. *Web of Science® Times Cited: 43 ... 2. Tseng SCG, Jarvinen MT, Nelson WG, Huang HW, Woodcock-Mitchell J, Sun TT. Correlation of specific keratins with different ...http://onlinelibrary.wiley.com/doi/10.1002/hep.510230312/references
Antibodies Specific for DNA Components Modified by Chemical Carcinogens and Their Binding Efficiency to DNA Modified in Vivo...
... detects femtomoles of acetylaminofluorene-DNA adducts, Carcinogenesis 1:455 (1980).PubMedCrossRefGoogle Scholar ... ethylnitrosourea or N-acetylaminofluorene, Carcinogenesis 6:263 (1985).PubMedCrossRefGoogle Scholar ... Implications for quantification of benzo(a)pyrene DNA adducts in vivo, Carcinogenesis 8:1263 (1987).PubMedCrossRefGoogle ... L. L. Hsieh, A. M. Jeffrey and R. M. Santella, Monoclonal antibodies to 1-aminopyrene-DNA, Carcinogenesis 6:1289 (1985).PubMed ...https://rd.springer.com/chapter/10.1007/978-1-4757-9640-7_13
ASMscience | Other Diseases Associate
de Boer, J., and, J. H. Hoeijmakers. 2000. Nucleotide excision repair and human syndromes. Carcinogenesis 21:453-460.. ... 2. Ahrens, C.,, M. Grewe,, M. Berneburg,, S. Grether-Beck,, X. Quilliet,, M. Mezzina,, A. Sarasin,, A. R. Lehmann,, C. F. ... Lambert, W. C., and, M. L. Lambert. 1985. Co-recessive inheritance: a model for DNA repair, genetic disease and carcinogenesis. ... pyrene-induced mutagenesis and carcinogenesis in repair-deficient Cockayne syndrome group B mice. Cancer Res. 60:5681-5687.. ...http://www.asmscience.org/content/book/10.1128/9781555816704.ch25