*  Dexamethasone - BML-EI126 - Enzo Life Sciences
A2 and C activities and arachidonic acid release from endothelial cells in response to bradykinin and leukotriene D4: M.A. ...
  http://www.enzolifesciences.com/BML-EI126/dexamethasone/
*  15-Hydroxyeicosatetraenoic acid - Wikipedia
... leukotriene D4, and E4. Formation of the leukotrienes is initiated by 5-lipoxygenase metabolism of arachidonic acid to form a 5 ... a metabolite of arachidonic acid. Various cell types metabolize arachidonic acid to 15(S)-hydroperoxyeicosatetraenoic acid (15( ... 13E-eicosatetraenoic acid (15(R)-HpETE). Human cells release arachidonic acid (i.e. 5Z,8Z,11Z,14Z-eicosatetraenoic acid) from ... Maas, R. L.; Turk, J; Oates, J. A.; Brash, A. R. (1982). "Formation of a novel dihydroxy acid from arachidonic acid by ...
  https://en.wikipedia.org/wiki/15-Hydroxyeicosatetraenoic_acid
*  Multiple Bradykinin Receptors: Results of Studies Using a Novel Class of Receptor Antagonists | SpringerLink
A2 and C activities and arachidonic acid release from endothelial cells in response to bradykinin and leukotriene D4, ... Arachidonic Acid Release Tissue Kallikrein Bradykinin Receptor High Molecular Weight Kininogen Bradykinin Antagonist ... Murayama, T., and Ui, M., 1976, Receptor-mediated inhibition of adenylate cyclase and stimulation of arachidonic acid release ... Boschcov, P., Paiva, A.C.M., Paiva, T.B., and Shimuta, S.I., 1984, Further evidence for the existence of two receptor sites for ...
  https://link.springer.com/chapter/10.1007/978-1-4757-5971-6_9
*  Role of a nonsteroidal anti-inflammatory agent, ibuprofen, in coronary revascularization after acute myocardial infarction |...
Inhibition of cyclooxygenase resulted in increased accumulation of nonesterified fatty acids, particularly arachidonic acid, in ... Ezra D, Boyd LM, Feuerstein G, Goldstein RE (1983) Coronary constriction by leukotriene C4, D4, and E4 in the intact pig heart ... Fiedler VB, Abram TS (1987) Effects of intracoronary leukotriene D4 infusion on the coronary circulation, hemodynamics, and ... Accumulation of unesterified arachidonic acid in ischemic canine myocardium. Circ Res 54:313-322PubMedGoogle Scholar ...
  https://link.springer.com/article/10.1007/BF01907014
*  The effect of leukotriene antagonists, lipoxygenase inhibitors and selected standards on leukotriene-mediated allergic...
D4, and E4are major contributors to the pathobiology of human bronchial asthma. Therefore, it is likely that compounds that ... I. Kennedy, M. Langley and C. J. Whelan,The release and metabolism of 3 H-arachidonic acid from guinea pig perfused lungs in ... A simple method for the study of the action of drugs on the release and metabolism of arachidonic acid. J. Pharmacol. Methods6 ... E. J. Goetzl,Mediators of immediate hypersensitivity derived from arachidonic acid. N. Eng. J. Med.303, 822-825 (1980).Google ...
  https://link.springer.com/article/10.1007/BF01967398
*  Lipoxygenase Inhibitors as Potential Cancer Chemopreventives | Cancer Epidemiology, Biomarkers & Prevention
Arachidonic acid metabolism of cytosolic fractions of Lewis lung carcinoma cells. Adv. Prostaglandin Thromboxane Leukotriene ... Miller A. M., Weiner R. S., Ziboh V. A. Evidence for the role of leukotrienes C4 and D4 as essential intermediates in CSF- ... which metabolizes arachidonic acid into 12(S)-HETE (54) ; the leukocyte type, or L-12-LO, which converts arachidonic acid or ... or 15-carbon atoms of arachidonic acid (17, 18, 19) . In cells, arachidonic acid is esterified to membrane phospholipids in the ...
  http://cebp.aacrjournals.org/content/8/5/467.long
*  Leukotriene - Wikipedia
Leukotrienes are a family of eicosanoid inflammatory mediators produced in leukocytes by the oxidation of arachidonic acid (AA ... leukotriene D4) is to trigger contractions in the smooth muscles lining the bronchioles; their overproduction is a major cause ... Leukotrienes are synthesized in the cell from arachidonic acid by arachidonate 5-lipoxygenase. The catalytic mechanism involves ... and the essential fatty acid eicosapentaenoic acid (EPA) by the enzyme arachidonate 5-lipoxygenase. Leukotrienes use lipid ...
  https://en.wikipedia.org/wiki/Leukotriene
*  Thomas V. McCaffrey | Moffitt Cancer Center
The effect of arachidonic acid metabolites on the ciliary beat frequency of human nasal mucosa in vitro. Acta Otolaryngol. 1992 ... Cyrus C, Yang B, McCaffrey T. Leukotrienes C4 and D4 increase the ciliary beat frequency in human upper airway mucosa in vitro ... 1984 Jun;92(3):308-311. Pubmedid: 6431371. *Mertz JS, McCaffrey TV, Kern EB. Role of the nasal airway in regulation of airway ... 1984 Oct;92(5):546-550. Pubmedid: 6438585. *Mertz JS, McCaffrey TV, Kern EB. Objective evaluation of anterior septal surgical ...
  https://moffitt.org/providers/thomas-mccaffrey/
*  flare ups in endodontics -1 etiological factors | Inflammation | Immune System
... the arachidonic acid is metabolized largely by a 5-lipooxygenase to a series of products called leukotrienes (43). One of these ... Loss of glutamic acid converts LT C4 into LT D4, which, in turn, forms LT E4 by the loss of glycine. This last group of ... They are derived from arachidonic acid, a 20-carbon polyunsaturated fatty acid in the cell membrane. The enzyme phospholipase ... It is the principal metabolite of arachidonic acid in mast cells. When these cells are activated by IgE, PGD2 participates in ...
  https://www.scribd.com/document/29924342/flare-ups-in-endodontics-1-etiological-factors
*  Effects of the Arachidonate Lipoxygenase Inhibitor BW755C on Traumatic and Peritumoural Brain Oedema | Springer for Research &...
It inhibits synthesis of prostaglandins and leukotrienes by inhibition in the cyclooxygenase and lipoxygenase pathways of... ... synthesis of prostaglandins and leukotrienes by inhibition in the cyclooxygenase and lipoxygenase pathways of arachidonic acid ... Species difference in increased vascular permeability by synthetic leukotriene C4 and D4. Prostaglandins 21: 637-648PubMed ... Aritake K, Wakai S, Asano T, Takakura K (1983) Peroxidation of arachidonic acid and brainoedema. Brain Nerve 35: 965-973PubMed ...
  https://rd.springer.com/chapter/10.1007/978-3-7091-9115-6_23
*  Patent US20050192356 - Synergistic anti-inflammatory pharmaceutical compositions and methods of use - Google Patenten
The invention also provides a method of reducing inflammation by administering a composition comprising a reduced isoalpha acid ... RIAA) and isoalpha acid (IAA) isolated from hops, wherein the RIAA and IAA are in a ratio of about 3:1 to about 1:10. ... and isoalpha acid (IAA) isolated from hops, wherein the RIAA and IAA are in a ratio of about 3:1 to about 1:10. ... The invention provides a composition comprising a reduced isoalpha acid (RIAA) ...
  https://www.google.be/patents/US20050192356
*  Specialized pro-resolving mediators - Wikipedia
SPM are metabolites of arachidonic acid (AA), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), or n-3 DPA (i.e. 7,10Z, ... and PUFA metabolites including in particular leukotrienes (e.g. LTB4), hydroxyeicosatetraenoic acids (e.g., 5-HETE, 12-HETE), ... Winkler JW, Orr SK, Dalli J, Cheng CY, Sanger JM, Chiang N, Petasis NA, Serhan CN (2016). "Resolvin D4 stereoassignment and its ... 16Z-docosapentaenoic acid or osbond acid) is an isomer of n-3 DPA (clupanodonic acid) differing form the latter fatty acid only ...
  https://en.wikipedia.org/wiki/Specialized_pro-resolving_mediators