*  Antibody microarray - Wikipedia
Currently the largest commercially available sandwich-based antibody array detects 1000 different proteins. Antibody arrays are ... Antibody arrays for high-throughput screening of antibody-antigen interactions. Nature Biotechnol. 18, 989 -994 Holt L. J., ... "Protein expression profiling by antibody array analysis with use of dried blood spot samples on filter paper". Journal of ... for protein microarray-based ligand binding assays was further developed by Roger Ekins and colleagues in the late 1980s. ...
  https://en.wikipedia.org/wiki/Antibody_microarray
*  Frozen tissue array - Wikipedia
Paraffin tissue array was developed during late years in the 1980s; this array can help scientists high throughput analyze gene ... especially analyze different protein levels with antibodies by immunohistochemistry. Various paraffin tissue arrays are now ... Consequently frozen tissue array should be the best tool for high throughput analysis on this purpose. Frozen tissue cores with ... Schoenberg Fejzo M, Slamon DJ: Frozen tumor tissue microarray technology for analysis of tumor RNA, DNA, and proteins. American ...
  https://en.wikipedia.org/wiki/Frozen_tissue_array
*  Molecular diagnostics - Wikipedia
High-throughput protein arrays can use complementary DNA or antibodies to bind and hence can detect many different proteins in ... As of 2010, assays that incorporate an array of antibodies against specific protein marker molecules are an emerging technology ... In the 1980s, the phrase was used in the names of companies such as Molecular Diagnostics Incorporated and Bethseda Research ... Molecular diagnostics can help diagnose the subtype-for example of infections and cancers-or the genetic analysis of a disease ...
  https://en.wikipedia.org/wiki/Molecular_diagnostics
*  Protocols and Video Articles Authored by Mitchel J. Doktycz
Optimized Beadmilling of Tissues for High-throughput RNA Production and Microarray-based Analyses Analytical Biochemistry. Sep ... Radiolabeled proteins were used to quantify the surface density of immobilized antibody and the efficiency of capture of the ... Positional Control of Catalyst Nanoparticles for the Synthesis of High Density Carbon Nanofiber Arrays Carbon. 2008 , Pubmed ID ... The diverse array of metal and metal oxides, the different sizes and shapes that can be prepared and the variety of possible ...
  https://www.jove.com/author/Mitchel++J._Doktycz
*  Proteomics - Wikipedia
... they may have higher throughput than antibody-based and they sometimes can identify and quantify proteins for which no antibody ... Another approach is the arraying of multiple protein types for the study of properties like protein-DNA, protein-protein and ... The structural analysis also helps to understand that where drugs bind to proteins and also show where proteins interact with ... The technology merges laser capture microdissection (LCM) with micro array technology, to produce reverse phase protein ...
  https://en.wikipedia.org/wiki/Proteomics
*  Molecular Recognition Laboratorium - OpenWetWare
Microarray technology as a universal tool for high-throughput analysis of biological systems, Comb Chem High Throughput Screen ... or mapping protein-protein interactions using functional protein arrays [Phizicky 2003 Mar 13]. Many of the PIDs in proteins ... The higher sensitivity of the so called synthetic approaches (yeast two-hybrid, phage display and peptide array technologies) ... evaluation for protein and antibody microarray applications, J Chromatogr A 1009, 97-104. ...
  https://openwetware.org/wiki/?title=Molecular_Recognition_Laboratorium&oldid=681598
*  Screening assays and methods - Presidents and Fellows of Harvard College
Results lead to a rapid high-throughput screening of hybridoma cells that product antibodies against specific antigens and also ... Additional analysis using synthetic peptide libraries based on the sequence of the protein likely is used to refine the ... it is possible to produce multiple arrays for screening by stamping or patterning the array onto multiple substrates, and to ... The development of hybridomas and related technologies in the 1970s and 1980s has led to monoclonal therapies, but economic and ...
  http://www.freepatentsonline.com/8835188.html
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... both at the mRNA and protein level. For protein analysis, flow cytometry is a powerful analytical tool for assessing quality of ... High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities. Authors: Colin W. Bell, Barbara E. ... fluorescent proteins fused to proteins of interest, or organic dyes conjugated to antibodies or other molecules of interest, ... The method enables the fabrication of patterns not feasible using other techniques, such as 3D arrays of disconnected silver ...
  https://www.jove.com/visualize/abstract/23405212/exposure-chlorpromazine-to-266-nm-laser-beam-generates-new-species
*  Microfluidics - Wikipedia
... a protein array is a miniature array where a multitude of different capture agents, most frequently monoclonal antibodies, are ... and high-throughput screening. Microfluidics emerged in the beginning of the 1980s and is used in the development of inkjet ... protein analysis, cell manipulation and analysis including cell viability analysis and microorganism capturing. By combining ... A drawback of DNA and protein arrays is that they are neither reconfigurable nor scalable after manufacture. Digital ...
  https://en.wikipedia.org/wiki/Microfluidics
*  An overview of recent developments in genomics and associated statistical methods | Philosophical Transactions of the Royal...
2003 Cap analysis of gene expression for high-throughput analysis of transcriptional starting point and identification of ... where protein chains form bridges to other genomic regions, or due to the cross reaction of the antibody with another protein ( ... is tiled on the array. Tiling arrays are powerful for genome-wide investigations, and have been used in many studies, such as ... During the 1980s and 1990s, the polymerase chain reaction (PCR; Bartlett & Stirling 2003), automated DNA sequencing, and ...
  http://rsta.royalsocietypublishing.org/content/367/1906/4313
*  Surface-Enhanced Raman Scattering as an Emerging Characterization and Detection Technique
H. Li, J. Sun, and B. M. Cullum, "Nanosphere-based SERS immuno-sensors for protein analysis," in Smart Medical and Biomedical ... A relatively low throughput and high cost of EBL tools makes them less attractive for scaled-up fabrication of SERS substrates ... J. D. Caldwell, O. Glembocki, F. J. Bezares et al., "Plasmonic nanopillar arrays for large-area, high-enhancement surface- ... This was because antibody-analyte interaction led to changes in the conformation of the antibody. The spectra showing the ...
  https://www.hindawi.com/journals/jnt/2012/971380/
*  Alternative splicing - Wikipedia
High-throughput approaches to investigate splicing have, however, been developed, such as: DNA microarray-based analyses, RNA- ... A trans-acting splicing regulatory protein of interest is then precipitated using specific antibodies. When the RNA attached to ... arrays from ExonHit or Jivan) have been used. The array is then probed with labeled cDNA from tissues of interest. The probe ... Examples of alternative splicing in immunoglobin gene transcripts in mammals were also observed in the early 1980s. Since then ...
  https://en.wikipedia.org/wiki/Alternative_splicing
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... high level of reporter protein production, and about two-fold higher biomass production under controlled environmental ... Quantitative Analyses of all Influenza Type A Viral Hemagglutinins and Neuraminidases using Universal Antibodies in Simple Slot ... rather than the number of probes that are immobilized on the array. Likewise, the total analysis time can be shortened or ... In the late 1980s and early 1990s, Stephenson and colleagues highlighted the possibility of STH infections lowering the ...
  https://www.jove.com/visualize/abstract/23349857/local-adaptation-to-altitude-underlies-divergent-thermal-physiology
*  Three-dimensional mesostructures as high-temperature growth templates, electronic cellular scaffolds, and self-propelled...
... and/or throughputs, others in access to high-performance materials, and yet others in compatibility with state-of-the-art 2D ... S7A). Quantitative mechanics analyses (SI Appendix, note 3) yield a simple scaling law for the springback ratio (ρs, defined in ... S9B shows SEM images of raised roof arrays in Au-PI (thickness: 50 nm/8 μm, ribbon width: 50 μm) on Cu foil with conductive ... 2E, PDMS as the adhesive) and a table-tent mixed array in PI (thickness: 8 μm, ribbon width: 50 μm) printed onto a piece of ...
  http://www.pnas.org/content/early/2017/10/24/1713805114
*  Combinatorial Chemistry | Encyclopedia.com
Other terms associated with this field are parallel array synthesis and high-throughput chemistry. ... different segments of antibody genes to generate a diverse pool of antibody molecules that can recognize and bind a wide array ... The analysis, or screening, of these libraries to identify the compounds of interest, along with their subsequent isolation and ... Typically, the molecules are arrayed on a solid surface and the target is added. Unbound target is washed away. Fluorescent ...
  https://www.encyclopedia.com/science-and-technology/chemistry/chemistry-general/combinatorial-chemistry
*  Thescientistoctober2014 by Alberto Arevalo - Issuu
ANALYSIS BY HIGH-THROUGHPUT SEQUENCING For researchers interested in making quantitative measurements of RNA-protein affinities ... Achieve high yields of antibodies and other proteins in suspension CHO and 293 cells • Compatible with multiple media ... The array is surgically placed in the macular region, responsible in a healthy retina for high-acuity vision, and covers an ... Ease of implantation and tiling of these wireless arrays to cover a wide visual field, combined with their high resolution, ...
  https://issuu.com/albertoarevalo2/docs/thescientistoctober2014
*  Clinical Diagnostics and Research
... systems and validated methods for high-throughput genotype analyses . ... Sample technologies are used to isolate and process DNA, RNA and proteins from biological ... samples such as blood or tissue. ... 1. How NGS data differs from array or qPCR assays. 2. Strategies for NGS sequencing: WGS, WES and Targeted DNA sequencing 3. ... Currently, a variety of thyroid antibody and hormone assays are available. Understanding the differences between these tests is ...
  https://www.labroots.com/virtual-event/clinical-diagnostics-2015
*  TRANSGENIC NON-HUMAN ANIMAL AND USES THEREOF - Patent application
0129] An embodiment of the invention is use in high throughput screening (HTS) methods. HTS is the automated, simultaneous ... Abbreviations: a, a-subunit of the G protein; β,β-subunit of the G protein; γ,γ-subunit of the G-protein; AC, adenylate cyclase ... Analysis of the Effects of Insulator Elements on Expression Levels [0160] In Table 9, the influence of adding insulator ... An array of receptacles can be any number of receptacles from at least one or more than one receptacle suitable for holding ...
  http://www.patentsencyclopedia.com/app/20120255041
*  Download An Introduction To Soil Mechanics And Foundations
... a ultrasound we go from Stathis Kalyvas to Live the movies in which the proteins of the common architecture at analysis have ... These high-core data are us to compensate personal copies between the physico-chemical studies of the models and their download ... Eramo is p27 imbalance energy arrays, and is also to emulsions, young tens, and the catalytic TRIP to be helpful neurons. shape ... The atom-efficient download an introduction to soil mechanics delivers placed for a array mediated on the imitation… OS in the ...
  http://pd19.org/ebook/download-an-introduction-to-soil-mechanics-and-foundations
*  Issue TOC | GEN
Get the latest in biotechnology through daily news coverage as well as analysis, features, tutorials, webinars, podcasts, and ... useful in generating and characterizing antibodies and in serving as robust probes for protein binding analyses Array formats ... The field of protein therapeutics has grown dramatically since the 1980s Analytical developments along the way have opened the ... are popular because they increase throughput and require only small quantities of reagents... more » ...
  https://www.genengnews.com/issue/toc/140
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... to alterations in protein abundance and to immune function. Vitellogenin, a yolk protein with adapted functions in hormonal ... In the late 1980s head-upright tilt testing was first utilized for diagnosing syncope2. Since then it has been used to assess ... The fixed microwire arrays described are well-suited for chronic implantation and allow for longitudinal recordings of neural ... Time-lapse movies compiled from several hours of imaging allow the analysis of myeloid cell behavior in situ in the intestinal ...
  https://www.jove.com/visualize/abstract/23468997/atropine-for-critical-care-intubation-cohort-264-children-reduced
*  Neuroscience
Aviva currently offers antibodies to more than 7,000 different protein targets due to our high throughput antibody production ... recombinant proteins and antibodies; gene-based and microRNA qPCR arrays; validated primers for microRNAs, human and mouse ... systems and validated methods for high-throughput genotype analyses . ... In the early 1980s, this was realized by both in vivo preclinical and ultimately human imaging of neurotransmitter (NT) systems ...
  https://www.labroots.com/virtual-event/neuroscience-2015/agenda/thu-mar-19
*  Molecular Diagnostics
High capacity magnetic supports for automated antibody and epitope-tagged protein purifications ... Performance assessment of RNA sequencing and expression arrays for transcriptome analysis in cancer research ... Utilizing high throughput, next-generation DNA and RNA sequence approaches, her ... research seeks to improve our understanding ... After spending several years at the bench ... developing gene expression array products, he transitioned to Product Marketing ...
  https://www.labroots.com/virtual-event/molecular-diagnostics-2016