*  Pharmaceutical drug - Wikipedia
In the 1950s new psychiatric drugs, notably the antipsychotic chlorpromazine, were designed in laboratories and slowly came ... and typical antipsychotics for psychosis. As of 2007, thousands of approved drugs have been developed. Increasingly, ... In the inter-war period, the first anti-bacterial agents such as the sulpha antibiotics were developed. The Second World War ... These were drugs that worked chiefly as anti-anxiety agents and muscle relaxants. The first benzodiazepine was Librium. Three ...
  https://en.wikipedia.org/wiki/Pharmaceutical_drug
*  CR gas - Wikipedia
CR was developed by the British Ministry of Defence as a riot control agent in the late 1950s and early 1960s. A report from ... The dibenz[b,f][1,4]oxazepine moiety is present in the typical antipsychotic drug loxapine, but, unlike CR, loxapine is not ... CR gas or dibenzoxazepine (also referred to as DBO), or its chemical name dibenz[b,f][1,4]oxazepine, is an incapacitating agent ... Mohammed ElBaradei also confirmed via Twitter that "tear gas with [a] nerve agent" is being used in Tahrir Square. The only gas ...
  https://en.wikipedia.org/wiki/CR_gas
*  Anatomy of an Epidemic - Wikipedia
... "invention of the antipsychotic Thorazine" emptied the asylums. His case begins by showing that during the late 1940s and 1950s ... now typical antipsychotics) due to their induction of "euphoric quietude"; minor tranquilizers (now benzodiazepines) and ... and the anti-tuberculosis agents isoniazid and iproniazid respectively. The psychiatric mechanisms of action of these drugs ... He views the "hyping" of the top-selling atypical antipsychotics as "one of the more embarrassing episodes in psychiatry's ...
  https://en.wikipedia.org/wiki/Anatomy_of_an_Epidemic
*  Psychopharmacology revolution - Wikipedia
Blockade of the D2 receptors is thought to underlie the antipsychotic effect of the typical antipsychotics. However, in the ... Minor chemical manipulations in the chemical structure of chlorpromazine was used to create novel antipsychotic agents such as ... Apparently, there was great resistance to the use of medicine in the treatment of mental disorders prior to the 1950s. It is, ... Nevertheless related agents such as phenelzine and isocarboxazid are still on the market. In addition, tranylcypromine is a non ...
  https://en.wikipedia.org/wiki/Psychopharmacology_revolution
*  Typical antipsychotic - Wikipedia
Typical antipsychotics are a class of antipsychotic drugs first developed in the 1950s and used to treat psychosis (in ... Treatment includes discontinuation of the offending agent and supportive care. The role of typical antipsychotics has come into ... The newer, second-generation antipsychotics, also known as atypical antipsychotics, have replaced the typical antipsychotics ... Typical antipsychotics may also be used for the treatment of acute mania, agitation, and other conditions. The first typical ...
  https://en.wikipedia.org/wiki/Typical_antipsychotic
*  Menstrual problems for women - Psychiatric Drugs
Some of these medications have been available since the mid-1950's. They are also called conventional "typical" antipsychotics ... Antimanic Agents » Chlorpromazine 25mg, 50mg, 100mg Tablets Chlorpromazine 25mg, 50mg, 100mg Tablets. PACKAGE LEAFLET: ... Antipsychotic medications. Antipsychotic medications have been available since the mid-1950's. The older … ... Antipsychotics » Zyprexa (Olanzapine) What Is ZYPREXA® (olanzapine)?. ZYPREXA is a brand name for a prescription medicine that ...
  https://www.psychiatricdrugs.net/tag/menstrual-problems-for-women/
*  Medication - Wikipedia
In the 1950s new psychiatric drugs, notably the antipsychotic chlorpromazine, were designed in laboratories and slowly came ... and typical antipsychotics for psychosis.[33]:23-24 As of 2007, thousands of approved drugs have been developed. Increasingly, ... antifungal, alkalinizing agents, quinolones, antibiotics, cholinergics, anticholinergics, antispasmodics, 5-alpha reductase ... Drugs increasingly became "the center of medical practice".[33]:22 In the 1950s other drugs emerged including corticosteroids ...
  https://en.m.wikipedia.org/wiki/Pharmaceuticals
*  Textbook of Psychiatry/Psychopharmacology - Wikibooks, open books for an open world
First Generation Antipsychotics (FGAs)[edit]. The first antipsychotic, chlorpromazine, was developed in the 1950s.(Meyer and ... Start: 5 mg po bid and increase over several days to typical dose of 30-60 mg total per day, maximum dose 300 mg/day. Potency: ... In adults, other agents with noradrenergic and/or dopaminergic effects may be helpful in the treatment of ADHD symptoms, ... Second Generation Antipsychotics (SGAs)[edit]. Second generation antipsychotics, also known as atypical antipsychotics, are ...
  https://en.wikibooks.org/wiki/Textbook_of_Psychiatry/Psychopharmacology
*  Antipsychotic - Wikipedia
First-generation antipsychotics, known as typical antipsychotics, were discovered in the 1950s. Most second-generation drugs, ... and second-generation agents. The efficacy of such drugs is suboptimal. Few patients achieve complete resolution of symptoms. ... may be treated with either typical or atypical antipsychotics, although atypical antipsychotics are usually preferred because ... Typical antipsychotics have equal drop-out and symptom relapse rates to atypicals when used at low to moderate dosages. ...
  https://en.wikipedia.org/wiki/Antipsychotic
*  Anti-psychotics for anxiety - Anxiety - MedHelp
The modern atypical antipsychotics actually are no better or safer than their 1950's Phenothiazine counterparts that they've ... Those three are the hallmark adverse consequences of atypical/typical antipsychotics. However, the atypicals carry additional ... The traditional agents are largely off-patent, are available in generic form, and generate no significant revenue. Chronic ... Anti-psychotics for anxiety Rkk71 Just throwing this out there, not trying to stir up anything if someone takes an anti ...
  https://www.medhelp.org/posts/Anxiety/Anti-psychotics-for-anxiety/show/588084
*  Phencyclidine - Wikipedia
Typical antipsychotics such as phenothiazines and haloperidol have been used to control psychotic symptoms, but may produce ... PCP was brought to market in the 1950s as an anesthetic pharmaceutical drug but was taken off the market in 1965 due to the ... The role of NMDAR antagonism in the effect of PCP, ketamine, and related dissociative agents was first published in the early ... These effects were not noted in its medicinal use in the 1950s and 1960s however, and reports of physical violence on PCP have ...
  https://en.wikipedia.org/wiki/Phencyclidine
*  Tardive dyskinesia - Wikipedia
Rates in those on atypical antipsychotics are about 20% while those on typical antipsychotics have rates of about 30%. Risk is ... Tardive dyskinesia was first described in the 1950s shortly after the introduction of chlorpromazine and other antipsychotic ... These agents are associated with fewer neuromotor side effects and a lower risk of developing tardive dyskinesia. Recent ... Some studies suggest that physicians should consider using atypical antipsychotics as a substitute to typical antipsychotics ...
  https://en.wikipedia.org/wiki/Tardive_dyskinesia
*  Dopamine - Wikipedia
Psychiatrists in the early 1950s discovered that a class of drugs known as typical antipsychotics (also known as major ... Similar dopamine antagonist drugs are also some of the most effective anti-nausea agents. Restless legs syndrome and attention ... The introduction of the first widely used antipsychotic, chlorpromazine (Thorazine), in the 1950s, led to the release of many ... By the 1970s researchers understood that these typical antipsychotics worked as antagonists on the D2 receptors. This ...
  https://en.wikipedia.org/wiki/Dopamine
*  Schizophrenia: Current Therapies | CNS Diseases
The atypical antipsychotics are discussed in greater detail than the typical antipsychotics because the atypical agents are ... Haloperidol was launched in the late 1950s and the drug has years' worth of data and clinical experience demonstrating its ... Schizophrenia: Atypical Antipsychotics. Typical Antipsychotics. The benefits of treatment with typical antipsychotics include a ... Atypical agents offer benefits in terms of efficacy and tolerability over typical antipsychotics. All antipsychotics are ...
  http://cnsdiseases.com/schizophrenia-current-therapies
*  Psychotropic drugs facts, information, pictures | Encyclopedia.com articles about Psychotropic drugs
Antipsychotic agents. Also known as neuroleptic agents, these medications are used to manage psychosis related to schizophrenia ... Given this undesirable side effect, atypical antipsychotics were developed. They differ from the typical antipsychotics in that ... But it was drugs such as chlorpromazine hydrochloride (Thorazine) and lithium, introduced in the 1950s that dramatically ... typical and atypical. The difference between these two groups lies in their mechanism of action. Typical antipsychotics are ...
  https://www.encyclopedia.com/medicine/drugs/pharmacology/psychotropic-drugs
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*  Schizophrenia - Wikipedia
Most people on antipsychotics have side effects. People on typical antipsychotics tend to have a higher rate of extrapyramidal ... Various agents have been explored for possible benefits in this area. There have been trials on drugs with anti-inflammatory ... The perception of individuals with psychosis as violent has more than doubled in prevalence since the 1950s, according to one ... It is unclear whether typical or atypical antipsychotics are better. In those who do not improve with other antipsychotics ...
  https://en.wikipedia.org/wiki/Schizophrenia
*  Psychiatric medication - Wikipedia
There are two categories of antipsychotics: second-generation antipsychotics and atypical antipsychotics. Most antipsychotics ... Developed in the 1950s onward, benzodiazepines were originally thought to be non-addictive at therapeutic doses, but are now ... Common mood stabilizers:[citation needed] Lithium carbonate (Carbolith), first and typical mood stabilizer Carbamazepine ( ... Antimanic Agent, Stimulant Prescription Drugs. ... Atypical antipsychotics are also used as mood stabilizers in ...
  https://en.wikipedia.org/wiki/Psychiatric_medication
*  Schizophrenia - Wikipedia
Most people on antipsychotics have side effects. People on typical antipsychotics tend to have a higher rate of extrapyramidal ... Various agents have been explored for possible benefits in this area.[215] There have been trials on drugs with anti- ... Long-term hospitalization is uncommon since deinstitutionalization beginning in the 1950s, although it still occurs.[16] ... It is unclear whether typical or atypical antipsychotics are better.[15] In those who do not improve with other antipsychotics ...
  https://en.m.wikipedia.org/wiki/Negative_symptoms
*  Schizophrenia Daily News Blog: CATIE Results - Perphenazine almost as good as newer drugs
... "typical") antipsychotic medication - or to Geodon (ziprasidone) the newest of the second generation or atypical antipsychotics ... first available in the 1950s) and newer (available since the 1990s) antipsychotic medications used to treat schizophrenia. ... The trial, he wrote, identifies Zyprexa as one of two drugs that appear to be more effective than other agents. The other drug ... Although EPS is associated to some degree with all the older "typical" antipsychotic medications, perphenazine is an effective ...
  http://www.schizophrenia.com/sznews/archives/002424.html
*  Autism therapies - Wikipedia
... and the typical antipsychotic haloperidol may be effective in reducing some behaviors, that haloperidol may be more effective ... Between the 1950s and 1970s LSD was studied, however, has not been studied since. Autism friendly Effects of equine assisted ... Thiamine tetrahydrofurfuryl disulfide (TTFD) is hypothesized to act as a chelating agent in children with autism. A 2002 pilot ... and antipsychotics. Only the antipsychotics have clearly demonstrated efficacy. Research has focused on atypical antipsychotics ...
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*  Schizophrenia
typical antipsychotic medications. Compared to the typical antipsychotics, the atypicals are associated with a lower incident ... with the calcium channel blocking agent nilvadipine added to an existing antipsychotic regimen. Psychosocial factors. A number ... Abram Hoffer in the 1950s. It was mainly for this experimental treatment of schizophrenia that LSD administration was legal, ... atypical antipsychotic medication) can be equally effective as older medication (called typical antipsychotic medication), but ...
  http://www.cs.mcgill.ca/~rwest/wikispeedia/wpcd/wp/s/Schizophrenia.htm
*  Autism: Practice Essentials, Background, Pathophysiology
No pharmacologic agent is effective in the treatment of the core behavioral manifestations of autistic disorder, but drugs may ... An example of a motion typical in autism occurs when the child places a hand with fingers separately outstretched before the ... In the 1950s and 1960s, Bruno Bettelheim popularized this idea. Since then, careful family studies have disproved the ... Second-generation antipsychotics (eg, risperidone, aripiprazole, ziprasidone) * SSRI antidepressants (eg, fluoxetine, ...
  https://emedicine.medscape.com/article/912781-overview
*  Schizoaffective Disorder Tests, Treatment & Symptoms
The typical treatment for schizoaffective disorder involves the individual taking an antipsychotic drug and possibly a mood ... They have been available since the mid-1950s, and although antipsychotics do not cure the illness, they greatly reduce the ... Most patients experience substantial improvement when receiving antipsychotic agents. Some patients, however, do not respond to ... Since 1989, a new class of antipsychotics (atypical antipsychotics) has been introduced. At clinically effective doses, very ...
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