*  20alpha-hydroxysteroid dehydrogenase - Wikipedia
"Expression of 17beta-hydroxysteroid dehydrogenase type 1 and type 2, P450 aromatase, and 20alpha-hydroxysteroid dehydrogenase ... hydroxysteroid dehydrogenase AKR1C1 Shikita M, Inano H, Tamaoki B (1967). "Further studies on 20-alpha-hydroxysteroid ... Other names in common use include 20alpha-hydroxy steroid dehydrogenase, 20alpha-hydroxy steroid dehydrogenase, 20alpha-HSD, ... In enzymology, a 20-α-hydroxysteroid dehydrogenase (EC 1.1.1.149) is an enzyme that catalyzes the chemical reaction 17alpha, ...
  https://en.wikipedia.org/wiki/20alpha-hydroxysteroid_dehydrogenase
*  Efficacy and Safety Assessment of T2345 in Ocular Hypertensive or Glaucomatous Patients
20 ALPHA-HYDROXYSTEROID DEHYDROGENASE. It catalyzes the reduction of PROSTAGLANDIN D2 and PROSTAGLANDIN H2, as well as the ... prostaglandin F2-alpha (FP receptors), and prostacyclin (IP receptors). ... Aldo-keto reductase that functions as a bi-directional 17 BETA, ...
  https://www.bioportfolio.com/resources/trial/63209/Efficacy-and-Safety-Assessment-of-T2345-in-Ocular-Hypertensive-or-Glaucomatous-Patients.html
*  HSD17B3 - Wikipedia
"Phenotypic variability in 17beta-hydroxysteroid dehydrogenase-3 deficiency and diagnostic pitfalls". Clinical Endocrinology. 67 ... "The identification of 5 alpha-reductase-2 and 17 beta-hydroxysteroid dehydrogenase-3 gene defects in male pseudohermaphrodites ... "Deleterious missense mutations and silent polymorphism in the human 17beta-hydroxysteroid dehydrogenase 3 gene (HSD17B3)". The ... "Entrez Gene: HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3". Ademola Akesode F, Meyer WJ, Migeon CJ (December 1977). "Male ...
  https://en.wikipedia.org/wiki/HSD17B3
*  CCUG 1827 Strain Passport - StrainInfo
Cloning of genes coding for 3-alpha-hydroxysteroid dehydrogenase and for (3-17)-beta-hydroxysteroid dehydrogenase from ... Identification of a novel steroid inducible gene associated with the beta hsd locus of Comamonas testosteroni ... Regulation of the steroid-inducible 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase gene in Comamonas testosteroni ... Molecular cloning, overexpression, and characterization of steroid-inducible 3alpha-hydroxysteroid dehydrogenase/carbonyl ...
  http://www.straininfo.net/strains/8322
*  A.E.Brain: Outgoing Mail
Typical examples include apparent change of sex due to 5-alpha-reductase deficiency(5ARD) or 17-beta-hydroxysteroid ... dehydrogenase deficiency (17BHDD).. In these cases, of which you probably are aware, a genetically male infant at birth appears ...
  http://aebrain.blogspot.com/2007/10/outgoing-mail.html
*  ARTICLES | Physiological Genomics
Motojima K. 17beta-hydroxysteroid dehydrogenase type 11 is a major peroxisome proliferator-activated receptor alpha-regulated ... and D-forms of enoyl-CoA hydratase/dehydrogenase enzymes of peroxisomal beta-oxidation system. J Biol Chem 278: 47232-47239, ... tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology 137: 354-366, 1996. ... Evidence for the suppression of apoptosis by the peroxisome proliferator activated receptor alpha (PPAR alpha). Carcinogenesis ...
  http://physiolgenomics.physiology.org/content/30/2/192?ijkey=84a3b6e30c76231506da2781fef5cd9c10c30519&keytype2=tf_ipsecsha
*  SRD5A2 - Wikipedia
"Entrez Gene: SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)". ... 1995). "A new deletion of the 5 alpha-reductase type 2 gene in a Turkish family with 5 alpha-reductase deficiency". Clin. ... 1996). "5 alpha-reductase-2 gene mutations in the Dominican Republic". J. Clin. Endocrinol. Metab. 81 (5): 1730-5. doi:10.1210/ ... 3-oxo-5α-steroid 4-dehydrogenase 2 is an enzyme that in humans is encoded by the SRD5A2 gene. Steroid 5α-reductase catalyzes ...
  https://en.wikipedia.org/wiki/SRD5A2
*  Plus it
... a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity. J Biol Chem 1993;268:12964-9. ... The SNP rs11648233 resides in the 17-beta-hydroxysteroid dehydrogenase II gene (HSD17B2), which functions in the pathway that ... Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, ...
  http://cancerdiscovery.aacrjournals.org/content/4/2/155
*  Medical Genetics Test Details - Baylor Genetics Laboratories - Baylor College of Medicine, Houston, Texas
ACYL-CoA DEHYDROGENASE, MEDIUM-CHAIN, DEFICIENCY OF; ACADMD (OMIM 201450). ACYL-CoA DEHYDROGENASE, SHORT-CHAIN, DEFICIENCY OF; ... ALPHA-METHYLACETOACETIC ACIDURIA (OMIM 203750). 17-BETA-HYDROXYSTEROID DEHYDROGENASE X DEFICIENCY (OMIM 300438). PROPIONIC ... 2-METHYLBUTYRYL-CoA DEHYDROGENASE DEFICIENCY (OMIM 610006). ACYL-CoA DEHYDROGENASE, SHORT/BRANCHED CHAIN; ACADSB (OMIM 600301) ... MULTIPLE ACYL-CoA DEHYDROGENASE DEFICIENCY; MADD (OMIM 231680). ISOBUTYRYL-CoA DEHYDROGENASE DEFICIENCY (OMIM 611283). ...
  https://www.bcm.edu/research/medical-genetics-labs/test_detail.cfm?testcode=4350
*  KEGG ENZYME: 1.1.1.239
3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+);. 3alpha,17beta-hydroxy steroid dehydrogenase;. 3alpha(17beta)-HSD;. 17- ... hydroxysteroid dehydrogenase distinct from 3 alpha-hydroxysteroid dehydrogenase in hamster liver. ... all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) ... Different from EC 1.1.1.50 3alpha-hydroxysteroid dehydrogenase (Si-specific) or EC 1.1.1.213 3alpha-hydroxysteroid ...
  http://www.genome.jp/dbget-bin/www_bget?ec:1.1.1.239
*  HSD17B2 - Wikipedia
... dehydrogenase 2". Moeller G, Adamski J (2006). "Multifunctionality of human 17beta-hydroxysteroid dehydrogenases". Mol. Cell. ... a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity". The Journal of Biological Chemistry. 268 (17): ... Dong Y, Qiu QQ, Debear J, Lathrop WF, Bertolini DR, Tamburini PP (Oct 1998). "17Beta-hydroxysteroid dehydrogenases in human ... ISBN 978-0-12-803608-2. Moeller G, Adamski J (2009). "Integrated view on 17beta-hydroxysteroid dehydrogenases". Mol. Cell. ...
  https://en.wikipedia.org/wiki/HSD17B2
*  Cervical ripening in humans: potential roles of estrogen, progesterone, and insulin-like growth factor-I. Changes in 17-beta,20...
20-alpha-hydroxysteroid dehydrogenase activity supporting an increase in the estrogen/progesterone ratio of human fetal ... 10-alpha-hydroxysteroid dehydrogenase changed at the time of parturition. Around this time, its activity resulted in the net ... 10-alpha-hydroxysteroid dehydrogenase and its affect on the estrogen-progesterone ratio in fetal membranes. The activity of 17- ... 10-alpha-hydroxysteroid dehydrogenase may play an important role in increasing the estrogen-progesterone ratio in fetal ...
  http://www.readabstracts.com/Health/Cervical-ripening-in-humans-potential-roles-of-estrogen-progesterone-and-insulin-like-growth-factor-.html
*  Anti-HSD17B6 antibody (ab62221) | Abcam
NAD+ dependent 3 alpha hydroxysteroid dehydrogenase 3 hydroxysteroid epimerase antibody. *NAD+ dependent 3 alpha hydroxysteroid ... 3(alpha >beta) hydroxysteroid epimerasel antibody. *3-alpha-,beta-HSE antibody. *3-alpha-,beta-hydroxysteroid epimerase ... Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards ... Estrogen receptor ß and 17ß-hydroxysteroid dehydrogenase type 6, a growth regulatory pathway that is lost in prostate cancer.. ...
  https://www.abcam.com/hsd17b6-antibody-ab62221.html
*  Symptoms Of Lupus Nephritis In Children | Signs Of Lupus - Symptoms and Types Of Lupus
carbohydrate metabolism: Glucose-6-phosphate dehydrogenase deficiency Pyruvate dehydrogenase deficiency Danon disease/glycogen ... testicular: enzymatic (5-alpha-reductase deficiency, 17-beta-hydroxysteroid dehydrogenase deficiency) Androgen receptor ( ... Hypoglycemia beta cell (Hyperinsulinism) G cell (Zollinger-Ellison syndrome). Hypothalamic/. pituitary axes ... X-Linked mental retardation: Coffin-Lowry syndrome Fragile X syndrome MASA syndrome X-linked alpha thalassemia mental ...
  http://signsoflupus.com/symptoms-of-lupus-nephritis-in-children/
*  List of diseases (M) - Wikipedia
Myoshi type Muscular dystrophy limb-girdle with beta-sarcoglycan deficiency Muscular dystrophy limb-girdle with delta- ... the upper lip Mediastinal endodermal sinus tumors Mediastinal syndrome Mediterranean fever Medium-chain Acyl-CoA dehydrogenase ... wasting renal Major depressive disorder Mal de debarquement Malakoplakia Malaria Male pseudohermaphroditism due to 17-beta- ... hydroxysteroid dehydrogenase deficiency Male pseudohermaphroditism due to 5-alpha-reductase 2 deficiency Male ...
  https://en.wikipedia.org/wiki/List_of_diseases_(M)
*  Flaxseeds
... through increased formation of transcription factors like ER-alpha and ER-beta), as well as anti-estrogenic (working against ... Bioavailability of [alpha]-linolenic acid from flaxseed diets as a function of the age of the subject. European Journal of ... Both can be excellent sources of omega-3 fatty acids (in the form of alpha-linolenic acid) and very good sources of fiber. As ... The primary omega-3 fatty acid in flaxseeds-alpha-linolenic acid, or ALA-can be helpful to the cardiovascular system in and of ...
  http://whfoods.com/genpage.php?tname=foodspice&dbid=81
*  HSD17B1 antibody [EP1682Y] Recombinant (ab51045) | Abcam
20 alpha-hydroxysteroid dehydrogenase antibody. *20-alpha-HSD antibody. *DHB1_HUMAN antibody ...
  http://www.abcam.com/hsd17b1-antibody-ep1682y-ab51045.html
*  Human Metabolome Database: Showing Protein 3-oxo-5-beta-steroid 4-dehydrogenase (HMDBP00550)
3-Beta-Hydroxysteroid Dehydrogenase Deficiency. *Adrenal Hyperplasia Type 3 or Congenital Adrenal Hyperplasia due to 21- ... The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as ... Showing Protein 3-oxo-5-beta-steroid 4-dehydrogenase (HMDBP00550). IdentificationBiological propertiesGene propertiesProtein ... 5-beta-Cholestan-3-one + NADP → Cholestenone + NADPH. details 17a,21-Dihydroxy-5b-pregnane-3,11,20-trione + NADP → Cortisone. ...
  http://www.hmdb.ca/proteins/HMDBP00550
*  Sex change - Wikipedia
17beta-HSD-3). A relative handful of male to female changes have been reported, and the etiologies of these are not well ... due to either 5-alpha-reductase deficiency (5alpha-RD-2) or 17-beta-hydroxysteroid dehydrogenase deficiency ( ... Cohen-Kettenis, Peggy T. (2005). "Gender Change in 46,XY Persons with 5α-Reductase-2 Deficiency and 17β-Hydroxysteroid ... Dehydrogenase-3 Deficiency". Archives of Sexual Behavior. 34 (4): 399-410. doi:10.1007/s10508-005-4339-4. PMID 16010463. ...
  https://en.wikipedia.org/wiki/Sex_change
*  AKR1C4 Gene - GeneCards | AK1C4 Protein | AK1C4 Antibody
Chlordecone Reductase; 3-Alpha Hydroxysteroid Dehydrogenase, Type I; Dihydrodiol Dehydrogenase 4 2 3 ... 21-Dihydroxy-5-beta-pregnane-3,11,20-trione. *17,21-Dihydroxy-5b-pregnane-3,11,20-trione ... 3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone ... 3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=AKR1C4
*  Human Metabolome Database: Showing metabocard for 7a-Hydroxy-5b-cholestan-3-one (HMDB0006892)
3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone ... 2. 3-oxo-5-beta-steroid 4-dehydrogenase. General function:. Involved in oxidoreductase activity. Specific function:. ... The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as ... Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3- ...
  http://www.hmdb.ca/metabolites/HMDB0006892
*  Recombinant human HSD3a protein (ab109831) | Abcam
3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone ... Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3- ...
  https://www.abcam.com/recombinant-human-hsd3a-protein-ab109831.html
*  Congenital adrenal hyperplasia - The Clinical Advisor
3-beta-hydroxysteroid dehydrogenase deficiency, and lipoid adrenal hyperplasia (STAR deficiency) present with decreased ... 11-beta hydroxylase deficiency may mimic 21 OHD CAH as it leads to virilization, but is associated with increased ... The concentration of 17-OHP is measured on a filter paper blood spot sample obtained by the heel-stick technique as used for ... A very elevated 17-hydroxyprogesterone concentration (,4,000 ng/dl) is diagnostic.. In a well appearing child suspected of CAH ...
  https://www.clinicaladvisor.com/pediatrics/congenital-adrenal-hyperplasia/article/620197/
*  Summary: Die Rolle der Sulfatasehemmung und andere Wirkungen von Tibolon auf die Brust
The sulfated 3 alpha-OH tibolone metabolite showed even irreversible inhibition of the sulfatase enzyme. In addition, it was ... found that the enzyme 17 beta-hydroxy-steroid dehydrogenase activity was also slightly inhibited and sulfotransferase activity ...
  http://www.kup.at/journals/summary/3815.html
*  Gestrinone - Wikipedia
"Inhibition of Rat Ovarian 3.BETA.-Hydroxysteroid Dehydrogenase (3.BETA.-HSD), 17.ALPHA.-Hydroxylase and 17, 20 Lyase by ... Gestrinone is the C18 methyl derivative of norgestrienone (17α-ethynyl-19-nor-δ9,11-testosterone) and the δ9,11 analogue of ... It is more specifically a derivative of norethisterone (17α-ethynyl-19-nortestosterone) and is a member of the gonane (18- ... The androgenic properties of gestrinone are more exploited in its derivative tetrahydrogestrinone (THG; 17α-ethyl-18-methyl-δ9, ...
  https://en.wikipedia.org/wiki/Gestrinone