Chloramphenicol acetyltransferase - Wikipedia
EC 220.127.116.11) that detoxifies the antibiotic chloramphenicol and is responsible for chloramphenicol resistance in bacteria. This ... Chloramphenicol binds in a deep pocket located at the boundary between adjacent subunits of the trimer, such that the majority ... The crystal structure of the type III enzyme from Escherichia coli with chloramphenicol bound has been determined. CAT is a ... Shaw WV, Packman LC, Burleigh BD, Dell A, Morris HR, Hartley BS (1979). "Primary structure of a chloramphenicol ...https://en.wikipedia.org/wiki/Chloramphenicol_acetyltransferase
Leicester Research Archive: Resistance to fusidic acid in Escherichia coli mediated by the type I variant of chloramphenicol...
EC 18.104.22.168), an enzyme which is an effector of chloramphenicol resistance. Resistance to chloramphenicol is a consequence of ... Resistance to fusidic acid in Escherichia coli mediated by the type I variant of chloramphenicol acetyltransferase. ... Determinations of antibiotic resistance levels and estimates of intracellular chloramphenicol acetyltransferase concentrations ... Plasmid-encoded fusidic acid resistance in Escherichia coli is mediated by a common variant of chloramphenicol ...https://lra.le.ac.uk/handle/2381/35120
Pneumococcal carriage and antibiotic susceptibility patterns from two cross-sectional colonization surveys among children aged ...
... chloramphenicol, levofloxacin, erythromycin, tetracycline, cotrimoxazole, and clindamycin); multidrug resistance (MDR) was ... Antibiotic nonsusceptibility was defined as intermediate susceptibility or resistance to ≥1 antibiotics (i.e., penicillin, ... and factors associated with resistance. Annual surveys were conducted in one urban and one rural site during 2009 and 2010 ... chloramphenicol, levofloxacin, erythromycin, tetracycline, cotrimoxazole, and clindamycin); multidrug resistance (MDR) was ...https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-016-2103-0
Studies on the therapeutic effect of propolis along with standard antibacterial drug in Salmonella enterica serovar Typhimurium...
Centers for Disease Control and Prevention (CDC) has described antibiotic resistance as one of the world's most pressing health ... Antibiotic resistance is an emerging public health problem. ... propolis has been used in combination with chloramphenicol, ... But the increasing resistance against these drugs in the present scenario has diverted the focus to some natural products or ... WHO rated antibiotic resistance as "one of the three greatest threats to human health". One important strategy employed to ...https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-016-1474-5
Multiply-Substituted Protease Variants - Patent application
... and selected for chloramphenicol resistance and protease activity. Method for Protein Production  Inoculate 1-50 μL of ... 1.28, 1.28, 1.24 and 1.23 respectively (Table 4), in a microswatch assay (WO 99/34011) under European conditions (15 grains per ... R45N-P14R 1.28 R45N-G258R 1.23 R170S-S216R 1.21 R45N-S216R 1.05 R170S-P14R 1.03 R45N-A1R 1.01 R170S-S49R 0.93 R45N-G61R 0.87 ... resistance gene that enables continuous cultural maintenance of plasmid-infected host cells by growth in antibiotic-containing ...http://www.patentsencyclopedia.com/app/20110091959
Persistence of Biomarker ATP and ATP-Generating Capability in Bacterial Cells and Spores Contaminating Spacecraft Materials...
Extreme spore UV resistance of Bacillus pumilus isolates obtained from an ultra-clean spacecraft assembly facility. Microb. ... or chloramphenicol (Cm) were added to final concentrations of 10 mM or 25 μg/ml, respectively. ... subtilis spores or 1.28 × 107 B. pumilus spores. ... of the microbial isolates exhibit elevated levels of resistance ...http://pubmedcentralcanada.ca/pmcc/articles/PMC2519281/
DailyMed - LINEZOLID - linezolid injection, solution
This resistance is mediated by the cfr (chloramphenicol-florfenicol) gene located on a plasmid which is transferable between ... 1.28. (0.66). 1.03. (0.62). 91.40. (39.30). 138.00. (42.10). 4.26. (1.65). 5.40. (2.06). 127. (48). 80. (29). ... Mechanisms of Resistance. In vitro studies have shown that point mutations in the 23S rRNA are associated with linezolid ... The linezolid resistance in these organisms is associated with a point mutation in the 23S rRNA (substitution of thymine for ...https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b721756c-3b5e-456d-a2f6-0d8a56cc7f35
Hepatitis C Virus Inhibits DNA Damage Repair through Reactive Oxygen and Nitrogen Species and by Interfering with the ATM-NBS1...
6B) and also between HepG2-core cells and control HepG2 cells expressing neomycin-resistance gene (Fig. 6C). To determine ... VDJ recombination efficiencies were determined by calculating the ratio of 250 μg/ml amphenicol- and 20 μg/ml chloramphenicol- ... The adjusted hazard ratio was 1.28 (21). Another large study, however, found no statistical association between HCV infection ... we used a hepatocyte cell line stably expressing the core protein and a control cell line with a neomycin-resistance gene, ...http://www.jimmunol.org/content/185/11/6985.long
Identification of a new promoter for the response regulator rcsB expression in Salmonella enterica serovar Typhimurium -...
Costa CS & Anton DN (2001) Role of the ftsA1p promoter in the resistance of mucoid mutants of Salmonella enterica to mecillinam ... 3, empty arrow); (2) an ≈1.28-kb product, which may have originated from degradation of the rcsD-rcsB mRNA; and (3) an ≈0.67-kb ... 1 and chloramphenicol at 25 μg mL−1. ... The glutamate-dependent acid resistance system in Escherichia ... somA and rcsC are important for systemic Salmonella enterica serovar Typhimurium infection and cationic peptide resistance. Mol ...http://onlinelibrary.wiley.com/doi/10.1111/j.1574-6968.2009.01771.x/full
US5733762A - Complexes of nucleic acid and polymer, their process of preparation and their use for the transfection of cells ...
... hygromycin resistance, neomycin resistance, and chloramphenicol acetyl transferase. ... 1.28 to 1.88 ppm: 6H of carbons 3, 4 and 4 of lysine 2.41 ppm: CH3 group of p-toluene sulfonate 2.75 ppm: trace of DMSO 2.97 ... ATPase activity of purified multidrug resistance-associated protein. Sandgren et al. 2002. Nuclear targeting of macromolecular ... NMR spectrum at 300 MHz in D2 O of polylysine, p-toluene sulfonate 1.28 to 1.88 ppm: 6H of carbons 3, 4 and 5 of the lysine ...https://patents.google.com/patent/US5733762A/en
Foodborne Illnesses and Antibiotic Resistance Associated with Zoonotic Pathogens Michael Doyle. - ppt download
Foodborne Illnesses and Antibiotic Resistance Associated with Zoonotic Pathogens Types of antibiotic-resistant foodborne ... decrease 1996-98Salmonella Newport 1.28% (2 or more antibiotics, 1996) 0.1 2004Salmonella Newport 1.741% increase25% (2 or more ... chloramphenicol, streptomycin, sulfamethoxazole, tetracycline, amoxicillin-clavulanic acid, cephalothin, cefoxitin, ceftiofur ... ACSSuT plus Resistance genes on chromosome Resistance genes on plasmid Epidemic in Europe (esp. 1990 - 2002) and present in USA ...http://slideplayer.com/slide/733177/
carbenicillin: Topics by WorldWideScience.org
... chloramphenicol and ciprofloxacin. Multiple drug resistance was prevalent among isolates. Although only a fraction of strains ... The antibody titers of mAb ascites (1G7, 2A11, 2D10 and 3F6) were determined as 1:2.56×107, 1:1.28×107, 1 :5.12 × 106 and 1: ... Two different patterns of linked transferable resistance were found among the transconjugants. The first comprised resistance ... chloramphenicol and ciprofloxacin. Multiple drug resistance was prevalent among isolates. Although only a fraction of strains ...https://worldwidescience.org/topicpages/c/carbenicillin.html
Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling - Isis, Pharmaceuticals
Methods for preparing oligonucleotide analogs which have improved nuclease resistance and improved cellular uptake are provided ... Evaluation of the resistance of natural oligonucleotides and oligonucleotide-mimicking macromolecules of the invention to ... To a stirred mixture of 5'-homothymidine [Etzold, et al., Chemical Communications 1968, 422] (51, 1.28. g, 5 mmol), N- ... Marcus-Sekura et al., Comparative Inhibition of Chloramphenicol Acetyltransferase Gene Expression by Antisense Oligonucleotide ...http://www.freepatentsonline.com/5386023.html
Patent US5534250 - Polymers containing diester units - Google Patents
Electrical devices and anti-scarring agents. US20050192647 *. Dec 7, 2004. Sep 1, 2005. Angiotech International Ag. Electrical ... Polymer gel containing chloramphenicol, prepared by radical polymerization of a water/DMSO (90:10) solution of the drug, ... and the solvent removed under reduced pressure to give 1.28 g (89%) of the title product. 1 H NMR (60 MHz, CDCl3): δ 1.58 (3 H ... Electrical devices and anti-scarring agents. US20050182467 *. Dec 7, 2004. Aug 18, 2005. Angiotech International Ag. Electrical ...http://www.google.com/patents/US5534250?dq=5958006
Antibiotics * Doxycycline, Amoxil, Flagyl, Zithromax, Bactrim, Erythromycin, Cipro, Macrobid, Keflex, Augmentin, Ampicillin,...
Persian shallot 'could help fight TB antibiotic resistance'. Properties in Persian shallots could boost the effects of ... Chloramphenicol BUY NOW. $1.28. Chloromycetin is used to treat serious infectious diseases such as meningitis, rickettsial ... ...http://pharmacymarketonline.com/medicine-products-antibiotics-en.html
John Zhou | University of Technology Sydney
The sorption coefficient of DEHP decreased with increasing SC, from 1.28 x 104ml g-1at 0.1 g l-1SC to 6.75 x 103 ml g-1at 14.66 ... Results showed that chloramphenicol removal. on biochar was pH dependent and maximum sorption occurred at pH 4.0-4.5. The ... By contrast, when the strength of the electrical field was reduced by increasing the distance between the nozzle and collector ... chloramphenicol fitted better with the Langmuir isotherm model than the Freundlich isotherm model with the. maximum Langmuir ...https://www.uts.edu.au/staff/junliang.zhou
ESCHERICHIA COLI CONTAINING MUTATED LPDA GENE AND APPLICATION THEREOF - Patent application
0122] First step, a chloramphenicol resistance gene was amplified by using the plasmid pACYC184 DNA (Mok et al., 1991. Nucleic ... 22.214.171.124), galP gene (GenBank No: ACA76443.1) encodes galactose MFS transporter, glf gene (GenBank No: AAA27691.1) encodes ... The colonies with ampicillin- and chloramphenicol-resistance were intermediate recombination bacteria.  The second ... containing chloramphenicol gene (cat) and levansucrase gene (sacB).  The DNA fragment containing chloramphenicol gene ( ...http://www.patentsencyclopedia.com/app/20160145648
METHODS FOR ALTERING LIPIDS IN ALGAE AND YEAST - Patent application
Targets for Metabolic Engineering of Stress Resistance, Plant Physiol. 120, 945-949..  42. Sanmartin-Suarez, C., Soto- ... 0332] 35 Bishop, D. G. & Smillie, R. M. The effect of chloramphenicol and cycloheximide on lipid synthesis during chloroplast ... Resveratrol 53.3 1.28E-03 Forskolin 45.3 7.33E-03 Epinephrine 44.9 7.79E-10 Erbstatin analog 40.5 2.42E-03 Salicylic acid 32.3 ... Targets for Metabolic Engineering of Stress Resistance. Plant Physiology 120, 945-949, doi:10.1104/pp. 120.4.945 (1999).. [0339 ...http://www.patentsencyclopedia.com/app/20130273620
TS23 Alpha-Amylase Variants With Altered Properties - Patent application
... antibiotic resistance such as ampicillin, kanamycin, chloramphenicol or tetracyclin resistance. Furthermore, the vector may ... 49 Q87R N272E 0 1.28 50 Q87R N272R N282E 1 1.10 53 Q87R N282E 0 1.47 54 Q87R N282R 2 1.25 55 Q87R 1 1.51 64 N225E -1 1.15 65 ... Positive transformants are grown for 22 hours at 37° C. in 5 ml LB+chloramphenicol. The Bacillus culture of each positive ... Examples of selectable markers include but are not limited to antimicrobials (e.g., hygromycin, bleomycin, or chloramphenicol) ...http://www.patentsencyclopedia.com/app/20100048446
Thermostable luciferases and methods of production - Patent application
Assay to Detect Resistance to Luciferase Inhibitor A 10 mM stock solution of luciferin is incubated at 50° C. in 50 mM ... 59. The method of claim 58 wherein the enzyme is luciferase, chloramphenicol acetyltransferase, beta-glucuronidase or beta- ... 40 1g4 1.06 1.28 0.77 0.985 40 1d4 1.69 1.23 0.73 1 40 0h9 1.26 1.21 0.63 0.998 40 2f6 3 1.07 0.49 0.981 40 7d6 3.09 1.058 1.09 ... Instrument settings: Cuvette gap: 0.2 cm Voltage: 2.5 kV Capacitance: 25 μF Resistance: 200 Ohms  ...http://www.patentsencyclopedia.com/app/20090137019
Increased sucrose levels mediate selective mRNA translation in Arabidopsis | BMC Plant Biology | Full Text
50 mg/mL Chloramphenicol, 80 mM beta-glycerophosphate, 1 mM Sodium Molybdate) and loaded on a 20-60% sucrose gradient. After ... A LysM receptor-like kinase plays a critical role in chitin signaling and fungal resistance in Arabidopsis. Plant Cell. 2008, ... 50 mg/mL Chloramphenicol, 80 mM beta-glycerophosphate, 1 mM Sodium Molybdate, protease inhibitor cocktail (Sigma Aldrich), ...https://0-bmcplantbiol-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/s12870-014-0306-3
AEROSOLS FOR SINUNASAL DRUG DELIVERY - Patent application
If the main aerosol flow itself vibrates, it is useful to add a resistance means to the exit nostril, such as an appropriate ... TABLE-US-00006 TABLE 6 Subject 1 Subject 2 Time [h] Retention [%] Time [h] Retention [%] 0.03 100 0.06 100 1.28 72.2 0.68 68.8 ... chloramphenicol, ethambutol, pyrazinamid, terizidon, dapson, prothionamid, fosfomycin, fucidinic acid, rifampicin, isoniazid, ...http://www.patentsencyclopedia.com/app/20100316576
Cytoxan - Other :: Sale Pharmacy
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