*  Interleukin-1 receptor type 1 (IPR004076) | InterPro | EMBL-EBI
... these have been termed type I and type II receptors [PMID: 8702856]. The receptors both exist in transmembrane (TM) and soluble ... Cloning and characterization of an alternatively processed human type II interleukin-1 receptor mRNA.. J. Biol. Chem. 271 20965 ... including the interleukin-6 receptor. A novel method for virus immune evasion has been proposed in which the product of one or ... A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist.. Nature 386 194 ...
  http://www.ebi.ac.uk/interpro/entry/IPR004076
*  Interleukin 1 receptor, type I - Wikipedia
1987). "The cell surface receptors for interleukin-1 alpha and interleukin-1 beta are identical". Nature. 324 (6094): 266-8. ... type I (IL1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL1R1 also denotes its human ... The protein encoded by this gene is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein is a ... Chua AO, Gubler U (1990). "Sequence of the cDNA for the human fibroblast type interleukin-1 receptor". Nucleic Acids Res. 17 ( ...
  https://en.wikipedia.org/wiki/Interleukin_1_receptor,_type_I
*  Interleukin 1 receptor, type II - Wikipedia
Larregina A, Morelli A, Kolkowski E, Fainboim L (Feb 1996). "Flow cytometric analysis of cytokine receptors on human Langerhans ... Gomez E, Morel G, Cavalier A, Liénard MO, Haour F, Courtens JL, Jégou B (Jun 1997). "Type I and type II interleukin-1 receptor ... type II (IL-1R2) also known as CD121b (Cluster of Differentiation 121b) is an interleukin receptor. IL1R2 also denotes its ... "Interleukin-13 and interleukin-4 act as interleukin-6 inducers in human microglial cells". Cytokine. 8 (8): 636-41. doi:10.1006 ...
  https://en.wikipedia.org/wiki/Interleukin_1_receptor,_type_II
*  Endothelial-Specific Knockdown of Interleukin-1 (IL-1) Type 1 Receptor Differentially Alters CNS Responses to IL-1 Depending on...
... which then stimulates neurons bearing specific prostaglandin receptors in specific regions of the brain, thereby activating ... 1994) Systemic interleukin-1 induces early and late patterns of c-fos mRNA expression in brain. J Neurosci 14:4951-4964. ... 2006) Circulating interleukin-6 induces fever through a STAT3-linked activation of COX-2 in the brain. Am J Physiol 291:R1316- ... 2002) Interleukin-1 beta exerts a myriad of effects in the brain and in particular in the hippocampus: analysis of some of ...
  http://www.jneurosci.org/content/27/39/10476
*  Anti-Interleukin 10 Receptor Monoclonal Antibody Is an Adjuvant for T Helper Cell Type 1 Responses to Soluble Antigen Only in...
... this will require signaling through Toll receptors as well as neutralization of endogenous suppressive molecules such as IL-10. ... Anti-Interleukin 10 Receptor Monoclonal Antibody Is an Adjuvant for T Helper Cell Type 1 Responses to Soluble Antigen Only in ... Anti-Interleukin 10 Receptor Monoclonal Antibody Is an Adjuvant for T Helper Cell Type 1 Responses to Soluble Antigen Only in ... 1996) A critical role for transforming growth factor β but not interleukin 4 in the suppression of T helper type 1-mediated ...
  http://jem.rupress.org/content/192/10/1529
*  IL1R2 Gene - GeneCards | IL1R2 Protein | IL1R2 Antibody
Interleukin 1 Receptor Type 2, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The ... type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to ... this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors. *IL1R2_HUMAN, ... This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=IL1R2
*  Frontiers | Dynamic Protein Acetylation in Plant-Pathogen Interactions | Plant Science
Toll/Interleukin1 receptor type R protein; RPM1, intracellular nucleotide binding-leucine-rich repeat R protein. ... nuclear receptors, cytoskeletal proteins, and enzymes involved in metabolism. Additionally, acetylation was shown to modify ... nucleotide-binding/leucine-rich repeat receptor; PRR, pattern recognition receptor; SA, salicylic acid. ... 2015). A receptor pair with an integrated decoy converts pathogen disabling of transcription factors to immunity. Cell 161, ...
  https://www.frontiersin.org/articles/10.3389/fpls.2016.00421/full
*  Analysis of interleukin (IL)-1beta IL-1 receptor antagonist, soluble IL-1 receptor type II and IL-1 accessory protein in HCV...
... soluble receptors type 1 and II, human IL-1 accessory protein) that, when secreted into the blood stream may serve as ... Analysis of interleukin (IL)-1beta IL-1 receptor antagonist, soluble IL-1 receptor type II and IL-1 accessory protein in HCV- ... Analysis of interleukin (IL)-1beta IL-1 receptor antagonist, soluble IL-1 receptor type II and IL-1 accessory protein in HCV- ... Hepatitis C virus (HCV) causes hepatitis, liver cirrhosis and hepatocellular carcinoma, and may also induce type II mixed ...
  https://www.iris.unict.it/handle/20.500.11769/31986
*  Pancreatic Beta Cell Death: Novel Potential Mechanisms in Diabetes Therapy
... and clinical studies related to type 1 and type 2 diabetes. The journal welcomes submissions focusing on the epidemiology, ... which is common in all members of the TNF receptor family [63]. Fas is expressed on the surface of several cellular types, and ... C. M. Larsen, M. Faulenbach, A. Vaag et al., "Interleukin-1-receptor antagonist in type 2 diabetes mellitus," The New England ... Conversely, the extrinsic pathway or the pathway mediated by cell death receptors initiates with the union of ligand belonging ...
  https://www.hindawi.com/journals/jdr/2018/9601801/
*  CD121a / IL1R1 antibody | acris-antibodies.com
Cell surface receptors for the 2 forms of IL1 are identical. IL1R Type I contains a single membrane spanning segment, a large ... High affinity binding and signalling by the type I IL1 receptor requires CD121a and the accessory protein, IL1 R AcP, which ... Purified recombinant protein of Human interleukin 1 receptor, type I (IL1R1). Human. > 95 % Preparation: .. Purity Detail: >95 ... Interleukin 1 (IL1), which has a role as a mediator in inflammation, consists of 2 separate but related proteins, IL1 alpha and ...
  https://www.acris-antibodies.com/target/cd121a-antibody-il1r1-antibody.htm
*  US5055289A - Interferon antibody therapeutic compositions having an extended serum half-life - Google Patents
Method of treating human EGF receptor-expressing gliomas using radiolabeled EGF receptor-specific MAB 425 ... Type I interferon blocking agents for prevention and treatment of psoriasis US20090191217A1 (en) * 2004-12-02. 2009-07-30. De ... Modified interleukin-2 and production thereof CA2015060C (en) * 1989-05-05. 2008-03-18. Michael G. Rosenblum. Novel antibody ... Presence of receptors for IgE on monkey mast cells. US6129916A (en) 2000-10-10. Method of Increasing activation on ...
  https://patents.google.com/patent/US5055289?oq=flatulence
*  Differential gene expression profile reveals deregulation of pregnancy specific β1 glycoprotein 9 early during colorectal...
3b). It is also possible that the type of APC mutation plays a role in the level and pattern of PSG9 transcription.. ... Rutherfurd KJ, Chou JY, Mansfield BC: A motif in PSG11s mediates binding to a receptor on the surface of the promonocyte cell ... N-terminal domain of most PSGs is also present in a variety of extracellular matrix proteins that bind to integrin receptors ... To determine whether induction of Wnt signaling in cells with wild type APC could induce PSG9 expression, RKO cells with wild ...
  https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-5-66
*  Combining patient proteomics and in vitro cardiomyocyte phenotype testing to identify potential mediators of heart failure with...
Transient receptor potential channel subfamily M member 2. 0.0431. C163B. Q9NR16. Scavenger receptor cysteine-rich type 1 ... Andreassi MG, Del Ry S, Palmieri C, Clerico A, Biagini A, Giannessi D. Up-regulation of 'clearance' receptors in patients with ... These extracellular functions are mediated by the toll-like receptor 4 (TLR4) [42, 43] or the receptor for advanced glycation ... Serum and urinary concentrations of calprotectin as markers of insulin resistance and type 2 diabetes. Eur J Endocrinol. 2012; ...
  https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-016-0774-3
*  Inflammation as a Driver of Adverse Left Ventricular Remodeling After Acute Myocardial Infarction | JACC: Journal of the...
1990) Soluble human complement receptor type 1: in vivo inhibitor of complement suppressing post-ischemic myocardial ... One family of these pattern recognition transmembrane receptors-the Toll-like receptors (TLRs)-activates nuclear factor-κB (NF- ... interleukin. LV. left ventricular. LVEDV. left ventricular end-diastolic volume. LVEF. left ventricular ejection fraction. ... 1996) Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein. The Soluble TNF Receptor Sepsis ...
  http://www.onlinejacc.org/content/67/17/2050
*  Interleukin receptor - Wikipedia
Interleukin-15 receptor Interleukin-21 receptor Interleukin-23 receptor Interleukin-27 receptor Type 2 interleukin receptors ... Interleukin-2 receptor Interleukin-3 receptor Interleukin-4 receptor Interleukin-5 receptor Interleukin-6 receptor Interleukin- ... Interleukin-10 receptor Interleukin-20 receptor Interleukin-22 receptor Interleukin-28 receptor Interleukin-1 receptor and ... 7 receptor Interleukin-9 receptor Interleukin-11 receptor Interleukin-12 receptor Interleukin-13 receptor ...
  https://en.wikipedia.org/wiki/Interleukin_receptor
*  Decoy receptors - Wikipedia
1994). "The type II "receptor" as a decoy target for interleukin 1 in polymorphonuclear leukocytes: characterization of ... Decoy receptors are being designed that bind to Gas6 and prevent Axl activation. ACE-031 is an engineered decoy receptor used ... It acts as an inhibitor, binding a ligand and keeping it from binding to its regular receptor. Decoy receptors participate in a ... A decoy receptor is a receptor that is able to recognize and bind specific growth factors or cytokines efficiently, but is not ...
  https://en.wikipedia.org/wiki/Decoy_receptors
*  IRAK4 - Wikipedia
IRAK4 is involved in signal transduction pathways stimulated by the cellular receptors belonging to the Toll/Interleukin-1 ... or Toll-like receptor-mediated immune responses (TLR), but was not essential to T-cell Receptor (TCR) signalling as was ... IRAK-4 (interleukin-1 receptor-associated kinase 4), in the IRAK family, is a protein kinase involved in signaling innate ... receptor superfamily. The Toll-Like Receptors (TLRs) are stimulated by recognition of pathogen-associated molecular patterns ( ...
  https://en.wikipedia.org/wiki/IRAK4
*  Toll-Interleukin receptor - Wikipedia
These proteins are type-I transmembrane receptors that share an intracellular 200 residue domain with the interleukin-1 ... "Identification of two major sites in the type I interleukin-1 receptor cytoplasmic region responsible for coupling to pro- ... receptor (IL-1R), the Toll/IL-1R homologous region (TIR). The similarity between Toll-like receptors (TLRs) and IL-1R is not ... The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signaling domain found in MyD88, interleukin-1 ...
  https://en.wikipedia.org/wiki/Toll-Interleukin_receptor
*  Alberto Mantovani - Wikipedia
Mantovani was able to identify the operating principle of the decoy receptor for interleukin - 1. In 1993, his team showed ... His works revealed the existence of decoy receptors in cell-signalling. He has been the most cited scientist in Italy, and one ... His team demonstrated in 2005 that the chemokine receptor D6 acts as a decoy and scavenger receptor for inflammatory chemokines ... His works help to establish the concept of "decoy receptors". From the study of the regulation of the cytokines, ...
  https://en.wikipedia.org/wiki/Alberto_Mantovani
*  MYD88 - Wikipedia
"Toll-like receptor 3 mediates a more potent antiviral response than Toll-like receptor 4". Journal of Immunology. 170 (7): 3565 ... Wesche H, Gao X, Li X, Kirschning CJ, Stark GR, Cao Z (Jul 1999). "IRAK-M is a novel member of the Pelle/interleukin-1 receptor ... Arancibia SA, Beltrán CJ, Aguirre IM, Silva P, Peralta AL, Malinarich F, Hermoso MA (2007). "Toll-like receptors are key ... type I RAC1 TLR 4 Various single nucleotide polymorphisms (SNPs) of the MyD88 have been identified. and for some of them an ...
  https://en.wikipedia.org/wiki/MYD88
*  Interleukin - Wikipedia
... these have been termed type I and type II receptors. The receptors both exist in transmembrane (TM) and soluble forms: the ... Gately MK, Renzetti LM, Magram J, Stern AS, Adorini L, Gubler U, Presky DH (1998). "The interleukin-12/interleukin-12-receptor ... Interleukin receptors on astrocytes in the hippocampus are also known to be involved in the development of spatial memories in ... Interleukin 9 (IL-9) is a cytokine that supports IL-2 independent and IL-4 independent growth of helper T cells. Interleukin 7 ...
  https://en.wikipedia.org/wiki/Interleukin
*  Interleukin 8 receptor, alpha - Wikipedia
"Expression of both types of human interleukin-8 receptors on mature neutrophils, monocytes, and natural killer cells". J. ... Interleukin Interleukin 8 Interleukin 8 receptor, beta Interleukin receptor Interleukin-8 receptor GRCh38: Ensembl release 89: ... Interleukin 8 receptor, alpha is a chemokine receptor. This name and the corresponding gene symbol IL8RA have been replaced by ... but not the type A, human interleukin-8 receptor". J. Biol. Chem. 271 (34): 20545-50. doi:10.1074/jbc.271.34.20545. PMID ...
  https://en.wikipedia.org/wiki/Interleukin_8_receptor,_alpha
*  Interleukin 8 receptor, beta - Wikipedia
"Expression of both types of human interleukin-8 receptors on mature neutrophils, monocytes, and natural killer cells". Journal ... Interleukin 8 receptor, alpha Interleukin 8 Interleukin Interleukin receptor Cluster of differentiation G protein-coupled ... Interleukin 8 receptor, beta is a chemokine receptor. IL8RB is also known as CXCR2, and CXCR2 is now the IUPHAR Committee on ... but not the type A, human interleukin-8 receptor". The Journal of Biological Chemistry. 271 (34): 20545-50. doi:10.1074/jbc. ...
  https://en.wikipedia.org/wiki/Interleukin_8_receptor,_beta
*  Interleukin-1 receptor associated kinase - Wikipedia
Toll-like receptors (TLRs) are important innate immune receptors that recognize pathogen associated molecular patterns (PAMPs) ... Inflammation signalling is known to be a major factor in many cancer types, and an inflammatory microclimate is a key aspect of ... and the B-cell activating receptor belonging to the TNF family (BAFF receptor). The alternative NF-κB pathway involves the ... Interleukin 1 is a cytokine that acts locally and systemically in the innate immune system. IL-1a and IL-1ß are known for ...
  https://en.wikipedia.org/wiki/Interleukin-1_receptor_associated_kinase
*  Interleukin 12 receptor, beta 1 subunit - Wikipedia
1997). "A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits". Proc. Natl. Acad ... Gubler U, Presky DH (1997). "Molecular biology of interleukin-12 receptors". Ann. N. Y. Acad. Sci. 795: 36-40. doi:10.1111/j. ... "Genetic variations in the interleukin-12/interleukin-23 receptor (beta1) chain, and implications for IL-12 and IL-23 receptor ... 1998). "Interleukin-12 induces tyrosine phosphorylation of an 85-kDa protein associated with the interleukin-12 receptor beta 1 ...
  https://en.wikipedia.org/wiki/Interleukin_12_receptor,_beta_1_subunit