*  HLA-DQ5 - Wikipedia
The β-chain of DQ is encoded by HLA-DQB1 locus and DQ5 are encoded by the HLA-DQB1*05 allele group. This group currently ... MuSK antibody-positive myasthenia gravis HLA-DR14-DQ5, probably DRB1*1402 : DQA1*0104 : DQB1*0503 (DR14-DQ5). DR1-DQ5 is ... HLA-DQ5 and HLA-DQB1*05 are almost synonymous in meaning. DQ5 β-chains combine with α-chains, encoded by genetically linked HLA ... These isoforms, are all HLA-DQ1 encoded by the DQA1*01 allele group. The efficiency of DQ1 recognition relative to DQ5 and DQ6 ...
  https://en.wikipedia.org/wiki/HLA-DQ5
*  HLA-DQ2 - Wikipedia
The β-chain of DQ is encoded by HLA-DQB1 locus and DQ2 are encoded by the HLA-DQB1*02 allele group. This group currently ... age of presentation in adults is influenced by HLA DRB1 and DQB1 genotypes (UKPDS 43). UK Prospective Diabetes Study (UKPDS) ... HLA-DQ2 and HLA-DQB1*02 are almost synonymous in meaning. DQ2 β-chains combine with α-chains, encoded by genetically linked HLA ... DQA1*03, *05 chains process to near identical alpha chains. The *04 chain can potentially complex with DQ2 forming DQ2.4. In ...
  https://en.wikipedia.org/wiki/HLA-DQ2
*  HLA class I histocompatibility antigen, A-33 alpha chain
HLA-A24 and HLA-A1 Supertypes in Chagasic Patients.. 26967484. 2016. The HLA Alleles B*0801 and DRB1*0301 Are Associated with ... HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and ... HLA-A24 and HLA-A1 Supertypes in Chagasic Patients.. 26967484. HLA-A alleles are associated with dermatitis herpetiformis in ... Hundreds of HLA-A alleles have been described. [provided by RefSeq, Jul 2008] ...
  https://pharos.nih.gov/idg/targets/P16190
*  HLA-DQ9 - Wikipedia
Törn C, Gupta M, Sanjeevi CB, Aberg A, Frid A, Landin-Olsson M (2004). "Different HLA-DR-DQ and MHC class I chain-related gene ... 2004). "HLA-DQA1 and DQB1 alleles are associated with genetic susceptibility to psoriasis vulgaris in Chinese Han". Int. J. ... Tsuchiya N, Kobayashi S, Hashimoto H, Ozaki S, Tokunaga K (2006). "Association of HLA-DRB1*0901-DQB1*0303 haplotype with ... HLA-DQ9 (DQ9) is a human leukocyte antigen serotype within the HLA-DQ (DQ) serotype group. DQ9 is a split antigen of the DQ3 ...
  https://en.wikipedia.org/wiki/HLA-DQ9
*  HLA B7-DR15-DQ6 - Wikipedia
HLA A*0201Cw*0702 : B*0702 : DRB1*1501 : DQA1*0102 : DQB1*0602 The gene-allele representation of the haplotype is: HLA A*0301Cw ... The other B7-DR2-DQ1 stems from the fact that DQ1 is an alpha chain serotype that is now covered by the beta chain type DQ5 and ... ISBN 0-19-262390-7. Middleton D, Williams F, Hamill M, Meenagh A (2000). "Frequency of HLA-B alleles in a Caucasoid population ... HLA B7-DR15-DQ6 is a representation(by serotype) of a common HLA haplotype found in Western Eurasia. The haplotype can be ...
  https://en.wikipedia.org/wiki/HLA_B7-DR15-DQ6
*  Histocompatibility leucocyte antigens and closely linked immunomodulatory genes in autoimmune thyroid disease - Murdoch...
Genotyping was performed using polymerase chain reaction and sequence specific primers for HLA Class I and II alleles and ... has been weakly associated with HLA DRB1*03, *04 and *11/*12 alleles (or DR3, DR4 and DR5). However, the presence of important ... 24% controls, P = 2 × 10−10, odds ratio (OR) 4·0]. Positive associations were also seen for DRB1*03 linked alleles, B*0801, ... Graves' disease (GD) is associated with the histocompatibility leucocyte antigen (HLA) haplotype A*01-B*0801-DRB1*0301-DQA1* ...
  http://researchrepository.murdoch.edu.au/id/eprint/5656/
*  Human leukocyte antigen - Wikipedia
HLA-DR *α-chain encoded by HLA-DRA locus. *4 β-chains (only 3 possible per person), encoded by HLA-DRB1, DRB3, DRB4, DRB5 loci ... alleles[19]. No. rare. alleles[17]. % rare. alleles[17]. No. very rare. alleles[17]. % very rare. alleles[17]. % alleles. ... HLA. Locus. No. common. alleles[19]. % common. alleles[19]. No. well-documented. alleles[19]. % well-documented. ... Of these, the most variable are HLA B and HLA DRB1. As of 2012, the number of alleles that have been determined are listed in ...
  https://en.wikipedia.org/wiki/Human_leucocyte_antigen
*  HLA Association with Drug-Induced Adverse Reactions
HLA-B. 38:02 and HLA-DRB1. 08:03. In addition, HLA-B. 15:02 allele was reported to be related to carbamazepine-induced SJS/TEN ... E. Hammond, C. Mamotte, D. Nolan, and S. Mallal, "HLA-B. 5701 typing: evaluation of an allele-specific polymerase chain ... HLA-DQA1, HLA-DQB1, HLA-DRA, and HLA-DRB1.. HLA class I molecules are expressed in almost all the cells and are responsible for ... The results showed strong associations of ATD-induced agranulocytosis with two alleles: HLA-B. 38:02 (. ) and HLA-DRB1. 08:03 ( ...
  https://www.hindawi.com/journals/jir/2017/3186328/
*  HLA-DR4 - Wikipedia
"Anti-caspase-8 autoantibody response in silicosis patients is associated with HLA-DRB1, DQB1 and DPB1 alleles". J Occup Health ... "A possible association between basic amino acids of position 13 of DRB1 chains and autoimmune hepatitis". Immunogenetics. 36 (1 ... HLA-DR4 (DR4) is an HLA-DR serotype that recognizes the DRB1*04 gene products. The DR4 serogroup is large and has a number of ... derived from IMGT/HLA Roudier J (2006). "HLA-DRB1 genes and extraarticular rheumatoid arthritis". Arthritis Research & Therapy ...
  https://en.wikipedia.org/wiki/HLA-DR4
*  Frontiers | T Cell-Mediated Chronic Inflammatory Diseases Are Candidates for Therapeutic Tolerance Induction with Heat Shock...
The HLA dictionary 2008: a summary of HLA-A,-B,-C,-DRB1/3/4/5, and-DQB1 alleles and their association with serologically ... The SE is a five amino-acid sequence motif found in residues 70-74 of the HLA-DRβ chain that encodes a conserved positively ... HLA-B27 encompasses around 105 known subtypes (HLA-B*27:01 to HLA-B*27:106 thus far identified) that are encoded by 132 alleles ... HLA-DRB1*0401-DQB1*0302 and HLA-DRB1*0301-DQB1*0201 have been associated with T1D susceptibility whereas the haplotypes HLA- ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2017.01408/full
*  Human leukocyte antigen - Wikipedia
Of these, the most variable are HLA B and HLA DRB1. As of 2012, the number of alleles that have been determined are listed in ... Major MHC class II HLA-DP α-chain encoded by HLA-DPA1 locus β-chain encoded by HLA-DPB1 locus HLA-DQ α-chain encoded by HLA- ... There are 3 major and 3 minor MHC class I genes in HLA. Major MHC class I HLA-A HLA-B HLA-C Minor genes are HLA-E, HLA-F and ... DQA1 locus β-chain encoded by HLA-DQB1 locus HLA-DR α-chain encoded by HLA-DRA locus 4 β-chains (only 3 possible per person), ...
  https://en.wikipedia.org/wiki/Human_leukocyte_antigen
*  HLA class I histocompatibility antigen, B-53 alpha chain
The HLA Alleles B*0801 and DRB1*0301 Are Associated with Dermatitis Herpetiformis in a Chinese Population.. ... HLA-B13:02, HLA-B38:02, HLA-B44:03, and HLA-B56:01 alleles were significantly increased in autistic subjects. HLA-B18:02 and ... HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and ... HLA-B alleles are associated with dermatitis herpetiformis in Chinese population.. 26841353. KIR-3DL2 binding to HLA-B27 ...
  https://pharos.nih.gov/idg/targets/P30491
*  Plus it
HLA DR3 was defined as DRB1*03:01 - DQA1*05:01 - DQB1*02:01, and HLA DR4-DQ8 was defined as DQA1*03:01 - DQB1*03:02 with DRB1* ... zero minor alleles) and also homozygous for the minor allele (two minor alleles) versus not (zero or one minor alleles). All ... Recent studies suggest a possible regulatory role of a TCF7L2 variant on acyl-CoA synthetase long-chain family member 5 (ACSL5 ... The protective HLA DRB1*15:01-DQB1*0602 haplotype was found in four noncarriers and in three carriers of the type 2 diabetes- ...
  http://care.diabetesjournals.org/content/41/2/311
*  HLA-C locus alleles may modulate the clinical expression of psoriatic arthritis | Arthritis Research & Therapy | Full Text
... but the presence of other HLA-C locus alleles may explain an additional arthritogenic risk. HLA-C alleles may modulate some ... HLA-Cw6-positive patients showed a longer psoriasis-arthritis latency period (p = 0.012). HLA-Cw*0701 was found under- ... HLA)-C locus alleles in determining the risk and the clinical expression of psoriatic arthritis (PsA). One hundred PsA patients ... A positive association was found between psoriatic spondylitis and HLA-Cw*0702 (OR 5.0; 95% CI 1.4 to 25; p = 0.01). HLA-Cw* ...
  https://arthritis-research.biomedcentral.com/articles/10.1186/ar2097
*  JCI Insight - Single-cell analysis of glandular T cell receptors in Sjögren's syndrome
HLA imputation. To confirm the presence of HLA DR3 and DQ2 alleles, classical HLA alleles were imputed from SNP data by the HLA ... Phototyping: comprehensive DNA typing for HLA-A, B, C, DRB1, DRB3, DRB4, DRB5 & DQB1 by PCR with 144 primer mixes utilizing ... During T cell development, the rearrangement of TCRβ chains is tightly regulated to ensure production of a single TCRβ chain in ... positive PCR screening tests for HLA DRB1*0301 (DR3) and DQB1*0201 (DQ2) alleles using previously described primers (61) and (b ...
  https://insight.jci.org/articles/view/85609
*  HLA-DQ1 - Wikipedia
HLA-DQ1 is a serotype that covers a broad range of HLA-DQ haplotypes. Historically it was identified as a DR-like alpha chain ... "HLA class II alleles in Japanese patients with Graves' disease: weak associations of HLA-DR and -DQ". Endocr. J. 41 (6): 599- ... 1994). "HLA-DQA1, -DQB1 and -DRB1 genotyping in Japanese pemphigus vulgaris patients by the PCR-RFLP method". Tissue Antigens. ... "Sequences related to HLA-DR alpha chain on human chromosome 6: restriction enzyme polymorphism detected with DC alpha chain ...
  https://en.wikipedia.org/wiki/HLA-DQ1
*  HLA-A33 - Wikipedia
For A33, the alpha "A" chain are encoded by the HLA-A*33 allele group and the β-chain are encoded by B2M locus. A33 and A*33 ... The DRB1*0609 haplotype in nodal in east/central Africa in the Ugandan, Rwanda, Congo, Cameroon whereas the allele is at low ... Allele Query Form IMGT/HLA - European Bioinformatics Institute Mohyuddin A, Mehdi SQ (2005). "HLA analysis of the Parsi ( ... 2007). "Genetic link between Chaoshan and other Chinese Han populations: Evidence from HLA-A and HLA-B allele frequency ...
  https://en.wikipedia.org/wiki/HLA-A33
*  In silicoanalysis of HLA associations with drug-induced liver injury: use of a HLA-genotyped DNA archive from healthy...
01 and HLA-DRB1 alleles. All haplotype combinations (colored lines) of the HLA-B*57:01 allele with HLA-DRB1 alleles reported in ... KIR, Killer-cell immunoglobulin-like receptors; MIC, MHC class I chain related (MIC) genes. ... HLA-A:HLA-B, HLA-B:HLA-C, HLA-B:HLA-DRB1, HLA-DRB1:HLA-DQB1. Additionally, we included the HLA-DQB1:HLA-DQA1 haplotype, which ... HLA-DRB1:HLA-DQB1 (D' = 0.95), HLA-B:HLA-C (D' = 0.94), HLA-B:HLA-DRB1 (D' = 0.68), HLA-A:HLA-B (D' = 0.60) and C:DRB1 (D' = ...
  https://genomemedicine.biomedcentral.com/articles/10.1186/gm350
*  Immunogenetic Risk and Protective Factors for Development of L-tryptophan-associated Eosinophilia-Myalgia Syndrome and...
Multivariate analyses showed that HLA DRB1*03, DRB1*04 and DQA1*0601 were risk factors as those alleles were more frequently ... Genomic DNA was isolated from peripheral blood and amplified by polymerase chain reactions using primers and sequence-specific ... HLA DRB1 and DQA1 allele typing and GM/KM phenotyping were performed on a cohort of 94 Caucasian subjects with documented LT ... Significant differences in allele frequencies were not observed for DRB1*04, DRB1*07, DQA1*0201 and DQA1*0501 in those with EMS ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2761987/
*  Protocols and Video Articles Authored by Clayton E. Mathews (Translated to Dutch)
The HLA molecules under investigation were HLA-DQ8 and -DR4, the two most prevalent HLA class II alleles found in Caucasian ... In addition, we also demonstrated that the diminished T-cell response varied according to the specific DRB1*04 alleles. Taken ... Superoxide (O(2)(.-)) from the Qo site of complex III of the electron transport chain accumulated in these cells and was ... namely how certain HLA molecules modulate the disease risk conferred by other HLA molecules. ...
  https://www.jove.com/author/Clayton+E._Mathews?language=Dutch
*  HLA-A*02 - Wikipedia
HLA-A02, and HLA-A*2. HLA-A*02 is one particular class I major histocompatibility complex (MHC) allele group at the HLA-A locus ... For A*02, the α chain is encoded by the HLA-A*02 gene and the β chain is encoded by the B2M locus. In 2010 the World Health ... DRB1*0401 : DQA1*0301 : DQB1*0302 Another haplotype that is more common in Central Europe is the (A2-B44-DR7-DQ2) A*0201 : C* ... "HLA Nomenclature @ hla.alleles.org". Anthony Nolan Research Institute. 10 Nov 2013. Retrieved 8 Dec 2013. "Allele Search Tool ...
  https://en.wikipedia.org/wiki/HLA-A*02
*  HLA A1-B8-DR3-DQ2 - Wikipedia
Two-point haplotype analysis between TNFB(B*01 allele) and HLA show that the allele is in linkage disequilibrium with HLA-A1, ... "Meta-analysis of HLA-DRB1 and HLA-DQB1 polymorphisms in Latin American patients with systemic lupus erythematosus". Autoimmun ... Starting from B8, immediately followed by the MICA and MICB which stand for MHC I-like chain A and B. These two functional ... In Kenya two slightly variant HLA-A and B alleles for an A1-B8 haplotype. One possibility is that peoples from central Asia or ...
  https://en.wikipedia.org/wiki/HLA_A1-B8-DR3-DQ2
*  JCI - Autoreactive T cells in type 1 diabetes
The HLA-DRB1 chain is also involved in the presentation of diabetogenic epitopes, but DRB1*04 variants differ in their disease ... Accordingly, 50%-60% of the genetic risk for T1D derives from HLA alleles encoding molecules involved in the presentation of ... Selected HLA-I variants such as HLA-A2, HLA-A24, HLA-B39, HLA-B57, and HLA-B18 contribute to T1D risk (3, 6). HLA-A2 is also ... HLA-II) haplotypes, especially HLA-DRB1*04 (DR4), DQA1*03:01-DQB1*03:02 (DQ8), HLA-DRB1*03:01 (DR3), and DQA1*05:01-DQB1*02:01 ...
  https://jinxiuwang.net.insight.mobile.jci.org/articles/view/94549
*  The first large population based twin study of coeliac disease | Gut
HLA typing. Each individual was typed for HLA class II DRB1 and DQB1 molecules. A Dynal AllSet+ SSP DR low resolution kit and a ... DZ twins sharing 0 or 1 alleles at the critical HLA region served as the reference category, and the risk of the non-index twin ... 28 The polymerase chain reaction products were then analysed by capillary electrophoresis on the ABI Prism 310 apparatus (PE ... The pairs in this group were: DRB1*07/07 (CD concordant), DRB1*07/08 (CD concordant), and DRB1*07/07 (CD discordant). ...
  http://gut.bmj.com/content/50/5/624
*  In silicoanalysis of HLA associations with drug-induced liver injury: use of a HLA-genotyped DNA archive from healthy...
We utilized novel in silico strategies to examine HLA haplotype relationships among the alleles associated with DILI by using ... Our bioinformatic analysis indicates that there may be a connection between the different HLA alleles associated with DILI ... Recently, genome-wide association studies have identified a number of human leukocyte antigen (HLA) alleles associated with ... To study these mechanisms, we established an HLA-typed cell archive from 400 healthy volunteers. In addition, we utilized HLA ...
  https://0-genomemedicine-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/gm350