*  Interleukin 5 receptor alpha subunit - Wikipedia
Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 ... Interleukin 5 receptor alpha subunit has been shown to interact with: Interleukin 5, Janus kinase 2, Protein unc-119 homolog, ... The receptor is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for ... "Interleukin 5 regulates the isoform expression of its own receptor alpha-subunit". Blood. 95 (5): 1600-7. PMID 10688814. ...
  https://en.wikipedia.org/wiki/Interleukin_5_receptor_alpha_subunit
*  Interleukin-7 receptor-α - Wikipedia
Interleukin-7 receptor subunit alpha (IL7R-α) also known as CD127 (Cluster of Differentiation 127) is a protein that in humans ... IL7R-α is a type I cytokine receptor and is a subunit of the functional Interleukin-7 receptor and Thymic Stromal Lymphopoietin ... "Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor ... 1992). "The interleukin-7 receptor gene is at 5p13". Hum. Genet. 89 (5): 566-8. doi:10.1007/BF00219186. PMID 1634235. Pleiman ...
  https://en.wikipedia.org/wiki/Interleukin-7_receptor-%CE%B1
*  Interleukin-5 receptor - Wikipedia
The interleukin-5 receptor is a type I cytokine receptor. It is a heterodimer of the interleukin 5 receptor alpha subunit and ... "JAK2 and JAK1 constitutively associate with an interleukin-5 (IL-5) receptor alpha and betac subunit, respectively, and are ... In fact, the β-subunit of the IL-5 receptor is also found in IL-3 and GM-CSF receptors where it is associated with IL-3Rα and ... Therefore, it is known as the common β receptor or βc. As with the IL-5Rα subunit, the β subunit's cytoplasmic domain is ...
  https://en.wikipedia.org/wiki/Interleukin-5_receptor
*  Interleukin 5 - Wikipedia
Interleukin 5 has been shown to interact with Interleukin 5 receptor alpha subunit. The IL-5 receptor is composed of an α and a ... "Binding interactions of human interleukin 5 with its receptor alpha subunit. Large scale production, structural, and functional ... is an interleukin produced by type-2 T helper cells and mast cells. Through binding to the interleukin-5 receptor, interleukin ... The α subunit is specific for the IL-5 molecule, whereas the βc subunit also recognised by interleukin 3 (IL3) and granulocyte- ...
  https://en.wikipedia.org/wiki/Interleukin_5
*  ADCY1 - Wikipedia
... alpha i-G alpha s chimeras define the function of alpha chain domains in control of G protein activation and beta gamma subunit ... "HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and ... Patke CL, Shearer WT (May 2000). "gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP ... It is inhibited by the G protein beta and gamma subunit complex. GRCh38: Ensembl release 89: ENSG00000164742 - Ensembl, May ...
  https://en.wikipedia.org/wiki/ADCY1
*  IL3RA - Wikipedia
Milatovich A, Kitamura T, Miyajima A, Francke U (1993). "Gene for the alpha-subunit of the human interleukin-3 receptor (IL3RA ... The receptor is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for ... "Structure of the gene encoding the alpha subunit of the human interleukin 3 receptor". Biochem. Biophys. Res. Commun. 208 (1): ... Interleukin 3 receptor, alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123), is a human gene. ...
  https://en.wikipedia.org/wiki/IL3RA
*  Interleukin-12 subunit beta - Wikipedia
Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and ... priming for IL-12 and tumor necrosis factor alpha production". J. Exp. Med. 181 (2): 537-46. doi:10.1084/jem.181.2.537. PMC ... IL-12B is a common subunit of interleukin 12 and Interleukin 23. This gene encodes a subunit of interleukin 12, a cytokine that ... Interleukin-12 p40 also serves as a subunit of Interleukin 23. GRCh38: Ensembl release 89: ENSG00000113302 - Ensembl, May 2017 ...
  https://en.wikipedia.org/wiki/Interleukin-12_subunit_beta
*  IL2RB - Wikipedia
"Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's". ... Interleukin-2 receptor subunit beta is a protein that in humans is encoded by the IL2RB gene. Also known as CD122; IL15RB; P70- ... This protein also forms one of the three subunits of the IL-15 receptor. Activation of the receptor increases proliferation of ... Purvis SF, Georges DL, Williams TM, Lederman MM (1992). "Suppression of interleukin-2 and interleukin-2 receptor expression in ...
  https://en.wikipedia.org/wiki/IL2RB
*  GNAI2 - Wikipedia
GNAI2 has been shown to interact with: EYA2, GPSM2, Interleukin 8 receptor, alpha, MDFI, RGS5, and RIC8A. GRCh38: Ensembl ... alpha i-G alpha s chimeras define the function of alpha chain domains in control of G protein activation and beta gamma subunit ... "Identification of G protein alpha-subunits in RINm5F cells and their selective interaction with galanin receptor". Diabetes. 40 ... "Distribution of the alpha-subunit of the guanine nucleotide-binding protein Gi2 and its comparison to G alpha o". Journal of ...
  https://en.wikipedia.org/wiki/GNAI2
*  Tumor necrosis factor receptor 1 - Wikipedia
This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate the transcription ... "Interleukin 1 receptor antagonist and soluble tumor necrosis factor receptor 1 are associated with general severity and ... "A protein related to a proteasomal subunit binds to the intracellular domain of the p55 TNF receptor upstream to its 'death ... Tumor necrosis factor receptor 1 (TNFR1), also known as tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) and ...
  https://en.wikipedia.org/wiki/Tumor_necrosis_factor_receptor_1
*  Interleukin-6 receptor - Wikipedia
IL6R subunit is also shared by many other cytokines. Interleukin-6 receptor has been shown to interact with Interleukin 6 and ... "Gene expression of the high molecular weight proteinase inhibitor alpha 2-macroglobulin". Biol. Chem. Hoppe-Seyler. 373 (7): ... is a type I cytokine receptor. Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and ... The interleukin-6 receptor can serve as an alpha-receptor for CTNF". J. Biol. Chem. 278 (11): 9528-35. doi:10.1074/jbc. ...
  https://en.wikipedia.org/wiki/Interleukin-6_receptor
*  Glycoprotein 130 - Wikipedia
It forms one subunit of the type I cytokine receptor within the IL-6 receptor family. It is often referred to as the common ... Barton VA, Hudson KR, Heath JK (1999). "Identification of three distinct receptor binding sites of murine interleukin-11". J. ... "Box 3-independent signaling mechanisms are involved in leukemia inhibitory factor receptor alpha- and gp130-mediated ... Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation". J. Biol. Chem. ...
  https://en.wikipedia.org/wiki/Glycoprotein_130
*  IKK2 - Wikipedia
Devin A, Lin Y, Yamaoka S, Li Z, Karin M (June 2001). "The α and β Subunits of IκB Kinase (IKK) Mediate TRAF2-Dependent IKK ... Zhang SQ, Kovalenko A, Cantarella G, Wallach D (March 2000). "Recruitment of the IKK signalosome to the p55 TNF receptor: RIP ... Windheim M, Stafford M, Peggie M, Cohen P (March 2008). "Interleukin-1 (IL-1) Induces the Lys63-Linked Polyubiquitination of IL ... NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK". Science. 278 (5339): 866-9. doi:10.1126/science. ...
  https://en.wikipedia.org/wiki/IKK2
*  Generation of competent bone marrow-derived antigen presenting cells from the deer mouse (Peromyscus maniculatus) | BMC...
A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific alpha chain and a beta chain shared with the ... that binds with high affinity to β chain subunit of the GM-CSF receptor complex that is shared with the IL-3 and IL-5 receptors ... Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors. Cell ... The 25-residue signal peptide is enclosed in box A. Helix A, which binds to the β chain subunit of the GM-CSF receptor, is ...
  https://bmcimmunol.biomedcentral.com/articles/10.1186/1471-2172-5-23
*  Frontiers | Simulation Study of cDNA Dataset to Investigate Possible Association of Differentially Expressed Genes of Human...
The functional enrichment analysis showed 6 down-regulated and 1 up-regulated genes. Among these DEGs, IL6 was associated with ... they secrete tumor necrosis factor alpha (TNF-α)-, interleukin-1 (IL-1), and interleukin-6 (IL-6), which further alter the ... This activity of the toxin resides in the A subunit and the pentamer of similar B subunit intercedes toxin binding to the Gb3 ( ... Tumor necrosis factor and interleukin-1 induce expression of the verocytotoxin receptor globotriaosylceramide on human ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2018.00380/full
*  STAT3 - Wikipedia
Ueda T, Bruchovsky N, Sadar MD (March 2002). "Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK ... Kim J, Kim D, Chung J (2000). "Replication protein a 32 kDa subunit (RPA p32) binds the SH2 domain of STAT3 and regulates its ... Kawasaki A, Matsumura I, Kataoka Y, Takigawa E, Nakajima K, Kanakura Y (May 2003). "Opposing effects of PML and PML/RAR alpha ... Zhang Z, Jones S, Hagood JS, Fuentes NL, Fuller GM (December 1997). "STAT3 acts as a co-activator of glucocorticoid receptor ...
  https://en.wikipedia.org/wiki/STAT3
*  Tyrosine kinase 2 - Wikipedia
1994). "Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 ... "Differential associations between the cytoplasmic regions of the interleukin-12 receptor subunits beta1 and beta2 and JAK ... "The amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta ... Recently, it has been recognized that IL-12 and IL-23 share ligand and receptor subunits that activate Tyk2. IL-10 is a ...
  https://en.wikipedia.org/wiki/Tyrosine_kinase_2
*  RELA - Wikipedia
"NF-kappaB and estrogen receptor alpha interactions: Differential function in estrogen receptor-negative and -positive hormone- ... "The RelA NF-kappaB subunit and the aryl hydrocarbon receptor (AhR) cooperate to transactivate the c-myc promoter in mammary ... "Transcriptional inhibition of interleukin-8 expression in tumor necrosis factor-tolerant cells: evidence for involvement of C/ ... Transcription factor p65 also known as nuclear factor NF-kappa-B p65 subunit is a protein that in humans is encoded by the RELA ...
  https://en.wikipedia.org/wiki/RELA
*  Janus kinase 2 - Wikipedia
"JAK2 and JAK1 constitutively associate with an interleukin-5 (IL-5) receptor alpha and betac subunit, respectively, and are ... "Physical interaction between interleukin-12 receptor beta 2 subunit and Jak2 tyrosine kinase: Jak2 associates with cytoplasmic ... the GM-CSF receptor family (IL-3R, IL-5R and GM-CSF-R), the gp130 receptor family (e.g., IL-6R), and the single chain receptors ... and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice". Endocrine ...
  https://en.wikipedia.org/wiki/Janus_kinase_2
*  Interleukin 3 - Wikipedia
"Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors". Cell ... induces disulfide-linked IL-3 receptor alpha- and beta-chain heterodimerization, which is required for receptor activation but ... Tabira T, Chui DH, Fan JP, Shirabe T, Konishi Y (1998). "Interleukin-3 and interleukin-3 receptors in the brain". Ann. N. Y. ... Interleukin 3 (IL-3) is a protein that in humans is encoded by the IL3 gene. Interleukin 3 is an interleukin, a type of ...
  https://en.wikipedia.org/wiki/Interleukin_3
*  A bi-functional IL-6-HaloTag® as a tool to measure the cell-surface expression of recombinant odorant receptors and to...
... as a tool to measure the cell-surface expression of recombinant odorant receptors and to facilitate their activity ... subunit alpha (Gαolf, GNAL) [4,13], as well as co-expression of accessory proteins and chaperones [11,15], such as receptor ... In the present protocol we use HaloTag®-ORs that are N-terminally extended by yet another tag, the interleukin 6 (IL-6), a ... Odorant receptors (ORs) are seven-transmembrane G protein-coupled receptors (GPCRs) [1], and are activated by small volatile ...
  http://www.jbmethods.org/jbm/article/view/207/190
*  NF-κB - Wikipedia
"Tumour necrosis factor-alpha (TNF-alpha) increases nuclear factor kappaB (NFkappaB) activity in and interleukin-8 (IL-8) ... Sheikh MS, Huang Y (2003). "Death receptor activation complexes: it takes two to activate TNF receptor 1". Cell Cycle. 2 (6): ... Unlike RelA, RelB, and c-Rel, the p50 and p52 NF-κB subunits do not contain transactivation domains in their C terminal halves ... interleukin 1-beta (IL-1β), bacterial lipopolysaccharides (LPS), isoproterenol, cocaine, and ionizing radiation. Receptor ...
  https://en.wikipedia.org/wiki/NF-%CE%BAB
*  Tumor necrosis factor alpha - Wikipedia
TNF can bind two receptors, TNFR1 (TNF receptor type 1; CD120a; p55/60) and TNFR2 (TNF receptor type 2; CD120b; p75/80). TNFR1 ... On the other hand, activated caspases cleave several components of the NF-κB pathway, including RIP, IKK, and the subunits of ... Large amounts of TNF are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). In the ... Tumor necrosis factor (TNF) alpha increases collagen accuulation and proliferation in intestinal myofibrobasts via TNF Receptor ...
  https://en.wikipedia.org/wiki/Tumor_necrosis_factor_alpha
*  PRKACG - Wikipedia
... gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit ... PRKACG has been shown to interact with Ryanodine receptor 2. GRCh38: Ensembl release 89: ENSG00000165059 - Ensembl, May 2017 " ... 1998). "Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via ... consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. ...
  https://en.wikipedia.org/wiki/PRKACG
*  Interleuchina 3 - Wikipedia
Stomski FC, Sun Q, Bagley CJ, et al., Human interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor alpha- and beta-chain ... Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors., in ... Tabira T, Chui DH, Fan JP, et al., Interleukin-3 and interleukin-3 receptors in the brain., in Ann. N. Y. Acad. Sci., vol. 840 ... induces disulfide-linked IL-3 receptor alpha- and beta-chain heterodimerization, which is required for receptor activation but ...
  https://it.wikipedia.org/wiki/Interleuchina_3