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*  Recessive von Willebrand disease type 2 Normandy: variable expression of mild hemophilia and VWD type 1 - Institutional...
Missense mutations in the von Willebrand factor (VWF) gene impairing the binding to factor VIII (FVIII) do not impair the ... Recessive von Willebrand disease type 2 Normandy: variable expression of mild hemophilia and VWD type 1 ...
  https://repository.uantwerpen.be/link/irua/77385
*  Expression and characterization of a codonoptimized blood coagulation factor VIII - Surrey Research Insight Open Access
Coagulation Factor VIII; LRP1 protein, human; von Willebrand Factor, Lentivirus; Hemophilia A ... secondary structures and binding to von Willebrand factor and to a fragment of the low-density lipoprotein receptor-related ... Background: Production of recombinant factor VIII (FVIII) is challenging due to its low expression. It was previously shown ... Expression and characterization of a codon-optimized blood coagulation factor VIII. J Thromb Haemost 2017; 15: 709-20, which ...
  http://epubs.surrey.ac.uk/813284/
*  Thrombotic Thrombocytopenic Purpura Conferences | Meetings | Events | Symposiums | OMICS Group
... a metalloprotease responsible for cleaving large multimers of von Willebrand factor (vWF) into smaller units. The increase in ...
  https://www.conferenceseries.com/thrombotic-thrombocytopenic-purpura.php
*  Von Willebrand Disease: Basic and Clinical Aspects
Since its discovery, von Willebrand disease has been extensively studied and the causative factor deficiency, the understanding ... This book summarizes recent research and will help to optimize the management of patients with von Willebrand disease. ... Von Willebrand Disease: Basic and Clinical Aspects provides an insight into all aspects of the condition. ... Home , Books , Von Willebrand Disease: Basic and Clinical Aspects View PDF. Von Willebrand Disease: Basic and Clinical Aspects ...
  http://ovid.com/site/catalog/books/12895.jsp
*  Two new candidate mutations in type IIA von Willebrand's disease (Arg834--|Gly, Gly846--|Arg) and one polymorphism (Tyr821--...
... several von Willebrand factor gene mutations resulting in type IIA von Willebrand's disease have been reported. We examined 8 ... Recently, several von Willebrand factor gene mutations resulting in type IIA von Willebrand's disease have been reported. We ... Genetic Analysis of 31 Swedish Type 1 von Willebrand Disease Families Reveals Incomplete Linkage to the von Willebrand Factor ... Extensive contacts between ADAMTS13 exosites and von Willebrand factor domain A2 contribute to substrate specificity.. * ...
  https://www.semanticscholar.org/paper/Two-new-candidate-mutations-in-type-IIA-von-Willeb-Donn%C3%A9r-Kristoffersson/5c7017779a42ce386676f17bbf626c42d97a089d
*  Bernard-Soulier Syndrome: Practice Essentials, Background, Pathophysiology and Etiology
2, 3, 4, 5] This complex is the receptor for von Willebrand factor (vWF), and the result of decreased expression is deficient ... complex which is the receptor for von Willebrand factor (vWF). ...
  https://emedicine.medscape.com/article/954877-overview
*  Factor VIII Market Share, Consumption and Revenue Forecast by Regions 2021
... the body circulating in the bloodstream in an inactive form in a stable noncovalent complex bound to von Willebrand factor vWF ... Factor VIII Market is classified, by type into Recombinant Factor VIII, Plasmaderived Factor VIII. Factor VIII Market is ... Factor VIII is a key factor of the intrinsic clotting cascade. Normal hemostasis requires at least a quarter of factor VIII ... Later on, recombinant factor VIII has been approved for therapeutic use, which lessens the risk of viral transmission. Factor ...
  http://b3.zcubes.com/v.aspx?mid=414850&
*  ASH 2017: HERCULES Trial: Caplacizumab Shows Dramatic Improvements for Acquired Thrombotic Thrombocytopenic Purpura - The ASCO...
... an enzyme that that cleaves von Willebrand Factor (vWF), a key protein involved in blood clotting. The disorder can emerge ...
  http://www.ascopost.com/News/58363
*  Continuous infusion of factor VIII concentrate to a patient with severe von Willebrand disease. - Semantic Scholar
Continuous infusion of factor VIII concentrate to a patient with severe von Willebrand disease.' by José Bruno Montoro et al. ... Continuous infusion of factor VIII concentrate to a patient with severe von Willebrand disease.. *. José Bruno Montoro. , ... article{Montoro1993ContinuousIO, title={Continuous infusion of factor VIII concentrate to a patient with severe von Willebrand ...
  https://www.semanticscholar.org/paper/Continuous-infusion-of-factor-VIII-concentrate-to-Montoro-Altisent/d0c3798bc1348380ae42acdc7fda533c7df6db01
*  Omega-3 Fatty Acids Modulate Weibel-Palade Body Degranulation and Actin Cytoskeleton Rearrangement in PMA-Stimulated Human...
Endothelial cells store von Willebrand factor (vWF) in cytoplasmic Weibel-Palade bodies (WPBs). We examined whether LC n-3 ... Endothelial cells store von Willebrand factor (vWF) in cytoplasmic Weibel-Palade bodies (WPBs). We examined whether LC n-3 ... FoR 1115 (Pharmacology and Pharmaceutical Sciences) , omega-3 fatty acids , von willebrand factor , weibel-palade bodies , ...
  http://research.usc.edu.au/vital/access/manager/Repository/usc:11380
*  Several systemic diseases including thrombotic thrombocytopenic purpura manifest much of their - GLO1 inhibitors for...
von Willebrand factor (VWF) a very large multimeric blood protein has a pivotal role in initiating haemostasis and thrombosis ... Platelet-Activating Factor (PAF) Receptors Recent Posts. * The use of vitamin K antagonists (VKAs), the cornerstone treatment ... and has emerged as an important risk factor and therapeutic target for many vascular diseases1 2 3 4 VWF is usually primarily ...
  http://bio-zentrum.com/several-systemic-diseases-including-thrombotic-thrombocytopenic-purpura-manifest-much-of-their/
*  Unraveling von Willebrand factor extracellular traps
Chapter 4: Severity of bleeding tendency in von Willebrand disease is associated with von Willebrand factor string formation. ... Chapter 3: Dextran sulfate blocks assembly of ultra large von Willebrand factor strings on the surface of endothelial cells. ... The main component of WPBs is von Willebrand factor (VWF), a multimeric glycoprotein which upon its release by endothelial ...
  http://dare.uva.nl/search?metis.record.id=400877
*  Vonvendi [von Willebrand factor New FDA Drug Approval | CenterWatch
For the on-demand treatment and control of bleeding episodes in adults with von Willebrand disease. New approved drug details ... non-von Willebrand factor containing) factor VIII if factor VIII baseline levels are below 40% or are unknown. The initial dose ... Vonvendi [von Willebrand factor (Recombinant)]. The following drug information is obtained from various newswires, published ... Vonvendi is a recombinant von Willebrand factor (VWF). Vonvendi is specifically indicated for on-demand treatment and control ...
  http://www.centerwatch.com/drug-information/fda-approved-drugs/drug/100121/vonvendi-von-willebrand-factor-recombinant
*  von Willebrand factor, type D domain (IPR001846) | InterPro | EMBL-EBI
One of the functions of von Willebrand factor (vWF) is to serve as a carrier of clotting factor VIII (FVIII). The native ... Conformational changes in the D' domain of von Willebrand factor induced by CYS 25 and CYS 95 mutations lead to factor VIII ... The secondary structure of the von Willebrand factor type A domain in factor B of human complement by Fourier transform ... The secondary structure of the von Willebrand factor type A domain in factor B of human complement by Fourier transform ...
  http://www.ebi.ac.uk/interpro/entry/IPR001846
*  Von Willebrand Factor (recombinant) Monograph for Professionals - Drugs.com
Von Willebrand Factor (recombinant) reference guide for safe and effective use from the American Society of Health-System ... Von Willebrand factor (recombinant) is a hemostatic.. Uses for Von Willebrand Factor (recombinant). Von Willebrand factor ( ... Von willebrand factor recombinant Intravenous (Advanced Reading). Professional resources. *Von Willebrand Factor (Recombinant) ... Von Willebrand factor (recombinant) is a recombinant von Willebrand factor (VWF) indicated for on-demand treatment and control ...
  https://www.drugs.com/monograph/von-willebrand-factor-recombinant.html
*  Anti-Von Willebrand Factor antibody (ab11713) | Abcam
Validated in ELISA, Flow Cyt, ICC/IF, ID, IHC-Fr to detect Human, Mouse Von Willebrand Factor. Referenced… ... Anti-Von Willebrand Factor antibody. See all Von Willebrand Factor primary antibodies. ... ab11713 staining Von Willebrand Factor in porcine heart tissue by Immunohistochemistry (Frozen sections).. Tissue was fixed in ... Immunohistochemistry (Frozen sections) - Anti-Von Willebrand Factor antibody (ab11713)This image is courtesy of an anonymous ...
  https://www.abcam.com/von-willebrand-factor-antibody-ab11713.html
*  Anti-Von Willebrand Factor antibody [3E2D10] (ab194405)
Mouse monoclonal Von Willebrand Factor antibody [3E2D10] validated for WB, IP, IHC, Flow Cyt, ICC/IF and tested in Human. ... Natural Human Von Willebrand Factor protein (ab88533) *Natural Human Von Willebrand Factor protein (factor VIII free) (ab88555 ... Anti-Von Willebrand Factor antibody [3E2D10]. See all Von Willebrand Factor primary antibodies. ... Immunohistochemical analysis of paraffin-embedded Human tonsil tissue labeling Von Willebrand Factor with ab194405 at 1.0 µg/mL ...
  http://www.abcam.com/von-willebrand-factor-antibody-3e2d10-ab194405.html
*  Human Von Willebrand Factor ELISA Kit | Abcam
Reliably quantify 2.5 mU/ml of Von Willebrand… ... Abcam's Von Willebrand Factor ELISA Kit (ab108918) suitable for ... Human Von Willebrand Factor ELISA Kit (VWF). See all Von Willebrand Factor kits. ... A Von Willebrand Factor specific antibody has been precoated onto 96-well plates and blocked. Standards or test samples are ... Human Von Willebrand Factor (VWF) in vitro ELISA (Enzyme-Linked Immunosorbent Assay) kit is designed for the quantitative ...
  http://www.abcam.com/human-von-willebrand-factor-elisa-kit-vwf-ab108918.html
*  Von Willebrand Factor Research Products: Novus Biologicals
Browse our Von Willebrand Factor product catalog backed by our Guarantee+. ... Von Willebrand Factor products available through Novus Biologicals. ... Diseases related to Von Willebrand Factor. Discover more about diseases related to Von Willebrand Factor.. Von Willebrand ... Von Willebrand Factor: An important mediator and carrier of hemostasis. Human Von Willebrand Factor (factor VIII R: Ag) is a ...
  https://www.novusbio.com/common-name/von-willebrand-factor
*  Erythrocytes and von Willebrand factor in venous thrombosis
... von Willebrand factor, and fibrin show a striking pattern in human venous thrombi by forming erythrocyte-von Willebrand factor- ... Erythrocytes and von Willebrand factor in venous thrombosis. Supervisors. P.L. Hordijk. ... Furthermore, the link between the ABO blood group system and von Willebrand factor is discussed. The thesis is concluded by a ... However, this thesis describes that erythrocytes can bind to von Willebrand factor and this interaction may contribute to the ...
  http://dare.uva.nl/search?identifier=14ea8c9d-f24e-4656-bb5f-b36013d26139
*  Degradation of Platelet-von Willebrand Factor Complexes by Plasmin | Circulation
Degradation of Platelet-von Willebrand Factor Complexes by Plasmin. An Alternative/Backup Mechanism to ADAMTS13. Anil K. ... von Willebrand factor. ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type I repeats-13) is a plasma protease ... that cleaves von Willebrand factor (VWF) and regulates its thrombogenicity. VWF is a multimeric glycoprotein that plays a key ... 3 The essential role of VWF in hemostasis is evidenced clinically in patients with von Willebrand disease, a bleeding disorder ...
  http://circ.ahajournals.org/content/129/12/1273.short?rss=1
*  Von Willebrand Factor Concentrate During ECMO Support - Full Text View - ClinicalTrials.gov
Active Comparator: Group W (von Willebrand factor concentrate) The patient receives von Willebrand factor concentrate (vWFC) as ... Acquired Von Willebrand Disease Drug: Von Willebrand Factor Drug: Saline Solution Phase 2 ... of von Willebrand factor (vWF) multimers occur leading to an acquired von Willebrand disease. This disease is associated with ... Von Willebrand Factor Concentrate During ECMO Support. The safety and scientific validity of this study is the responsibility ...
  https://www.clinicaltrials.gov/ct2/show/NCT03613584?term=Inherited+Bleeding+Disorder&
*  Von Willebrand Factor and Development of Diabetic Nephropathy in IDDM | Diabetes
Von Willebrand Factor and Development of Diabetic Nephropathy in IDDM. Coen D A Stehouwer, Erik S G Stroes, Wil H L Hackeng, ... Von Willebrand Factor and Development of Diabetic Nephropathy in IDDM. Coen D A Stehouwer, Erik S G Stroes, Wil H L Hackeng, ... Von Willebrand Factor and Development of Diabetic Nephropathy in IDDM Message Subject (Your Name) has forwarded a page to you ... indicated by an increase in plasma level of von Willebrand factor (vWF), is present in patients with insulin-dependent diabetes ...
  http://diabetes.diabetesjournals.org/content/40/8/971
*  Von willebrand factor test - Answers on HealthTap
... trusted information on the use of Ristocetin Cofactor for Von Willebrand: Dr. Engel on von willebrand factor test: Von ... Childbirth can be challenging with von willebrand due to the increased risk for bleeding. This can be managed by a hematologist ... willebrand does not affect fertility, so getting pregnant is typically not an issue. ... Von Willebrand (Definition) Von Willebrand disease is caused by a deficiency of von Willebrand factor. Von Willebrand factor ...
  https://www.healthtap.com/topics/von-willebrand-factor-test
*  Von Willebrand Factor Linked to Bleeding Complications - MPR
... treated patients with high levels of von Willebrand factor (VWF) have elevated risks of bleeding complications and ... HealthDay News) - Oral anticoagulation (OAC)-treated patients with high levels of von Willebrand factor (VWF) have elevated ...
  http://www.empr.com/medical-news/von-willebrand-factor-linked-to-bleeding-complications/article/231379/