Telomere and Telomerase - No Study Results Posted - ClinicalTrials.gov
Telomere and Telomerase. The safety and scientific validity of this study is the responsibility of the study sponsor and ...https://clinicaltrials.gov/ct2/show/results/NCT01176422
Human Telomerase Reverse Transcriptase Messenger RNA (hTERT mRNA) Transfected Dendritic Cell Vaccines - Full Text View -...
Human Telomerase Reverse Transcriptase Messenger RNA (hTERT mRNA) Transfected Dendritic Cell Vaccines. The safety and ... One of these proteins is called telomerase, which is found on prostate cancers and is critically important for prostate cancer ... Phase II Study of Active Immunotherapy With Mature, Human Telomerase Reverse Transcriptase Messenger RNA -Transfected, ... And effective in boosting the patient body's immunity against telomerase expressing prostate cancer cells. ...https://clinicaltrials.gov/ct2/show/NCT01153113
Open Label Study to Evaluate the Activity of Imetelstat in Patients With Essential Thrombocythemia or Polycythemia Vera - Full...
Telomerase Inhibitor Imetelstat in Patients with Essential Thrombocythemia. N Engl J Med. 2015 Sep 3;373(10):920-8. doi: ...https://clinicaltrials.gov/ct2/show/NCT01243073?term=McDevitt+AND+polycythemia+vera&rank=1
Efficacy of Mindful Tai Chi on Obese or Overweight Adults: A Randomized Controlled Clinical Trial - Full Text View -...
... and telomerase activity in leukocytes. A battery of questionnaires will measure psychological, cognitive-affective, socio- ...https://clinicaltrials.gov/ct2/show/NCT01264029?term=11-NR-0030&rank=1
Switch to Maraviroc + Integrase Inhibitor - Full Text View - ClinicalTrials.gov
Telomerase activity and telomere length measured at baseline and 24, 48, and 96 weeks. ...https://clinicaltrials.gov/ct2/show/NCT01896921?term=%22+June+08%2C++2013%22%3A%22+July+08%2C++2013%22%5BFIRST-RECEIVED-DATE%5DAND+HIV%5BCONDITION%5D&rank=12
Search of: complementary OR alternative OR integrative AND Pain - List Results - ClinicalTrials.gov
Telomerase activity from blood sample leucocyte cells. *Hb - hemoglobin status. *(and 18 more...) ...https://clinicaltrials.gov/ct2/results?term=complementary+OR+alternative+OR+integrative+AND+Pain
Danazol for Genetic Bone Marrow and Lung Disorders - Full Text View - ClinicalTrials.gov
These findings implicated telomerase dysfunction in failed hematopoiesis. In family members of probands with SAA, telomerase ... Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia. N Engl J Med. 2005 Apr 7;352(14):1413-24. ... In retrospect, the beneficial effects of sex hormones on telomerase activity may be the mechanism by which SAA patients treated ... However, the discovery of loss-of-function mutations in genes of the telomerase complex (TERC, TERT) established a genetic ...https://clinicaltrials.gov/ct2/show/NCT01441037?term=aplastic+anemia&recr=Open&fund=01&rank=10
Search of: CHOLANGITIS, PRIMARY SCLEROSING - List Results - ClinicalTrials.gov
number of cells with increased telomerase RNA component (TERC) expression. 60. All. 18 Years to 80 Years (Adult, Senior). ...https://clinicaltrials.gov/ct2/results?cond=CHOLANGITIS%2C+PRIMARY+SCLEROSING&show_flds=Y
Search of: trastuzumab - List Results - ClinicalTrials.gov
A Study Inhibiting Telomerase to Reverse Trastuzumab Resistance in HER2+ Breast Cancer. *Breast Neoplasms ... Tumor biopsy and bone marrow aspirate assayed for telomerase activity prior to treatment and immediately prior to planned cycle ...https://clinicaltrials.gov/ct2/results?term=trastuzumab
Combined Tretinoin and Arsenic Trioxide for Patients With Newly Diagnosed Acute Promyelocytic Leukemia Followed by Risk-Adapted...
Explore the in vivo induction of telomerase-dependent cell death [ Time Frame: 4 years ]. by ATRA (Tretinoin) and ATO (Arsenic ... Trioxide). Bone marrow samples will be analyzed at baseline and at the time of clinical CR for telomerase activity, telomere ...https://clinicaltrials.gov/ct2/show/NCT01404949?cond=%22Acute+promyelocytic+leukemia%22&rank=12
Collecting and Storing Tissue From Young Patients With Cancer - Full Text View - ClinicalTrials.gov
All cell types: telomerase expression including hTR and hTERT Mutations of TP53 gene are detected by flow cytometry and/or ... telomerase) and the expression of molecular markers that may correlate with drug resistance [ Time Frame: length of study ]. ... telomerase) and the expression of molecular markers that may correlate with drug resistance. ...https://clinicaltrials.gov/show/NCT00898755
Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic...
Dyskeratosis: diagnosis is supported by using either telomerase reverse transcriptase (TERC) gene mutation in autosomal ...https://clinicaltrials.gov/ct2/show/NCT00856388?cond=ADULT+SYNDROME&rank=9
S0421, Docetaxel and Prednisone With or Without Atrasentan in Treating Patients With Stage IV Prostate Cancer and Bone...
Goldkorn A, Ely B, Quinn DI, et al.: Results of telomerase activity measurements from live circulating tumor cells captured on ...https://clinicaltrials.gov/ct2/show/NCT00134056
Development of iPS From Donated Somatic Cells of Patients With Neurological Diseases - Full Text View - ClinicalTrials.gov
... telomerase activity, gene expression profile and in their capability to differentiate into progeny of the three germ layers ...https://clinicaltrials.gov/ct2/show/NCT00874783?term=Ataxia+Telangiectasia&rank=8
Phase 2 Study of Docetaxel +/- OGX-427 in Patients With Relapsed or Refractory Metastatic Bladder Cancer - Full Text View -...
Effect of Therapy Regimen on Circulating Tumor Cells (CTCs)and Correlative Analysis of Telomerase Activity [ Time Frame: Prior ... and levels of telomerase by quantitative polymerase chain reaction (PCR), and explore their relation with clinical outcomes. ...https://clinicaltrials.gov/show/NCT01780545
Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant...
... diagnosis is supported by using either telomerase RNA component (TERC) gene mutation in autosomal dominant Dyskeratosis ...https://clinicaltrials.gov/ct2/show/NCT01529827?cond=Thrombocytopenia%2C+x-linked&rank=7
Stem Cell Transplant, Chemotherapy, and Biological Therapy in Treating Patients With High-Risk or Refractory Multiple Myeloma -...
... the catalytic subunit of telomerase) and survivin. ...https://clinicaltrials.gov/ct2/show/record/NCT00499577
Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family Members -...
Natural history of pulmonary fibrosis in two subjects with the same telomerase mutation. Chest. 2011 May;139(5):1203-1209. doi ...https://clinicaltrials.gov/ct2/show/NCT00071045
Combination Chemotherapy Alone or With Radiation Therapy in Treating Children With Kidney Cancer - Full Text View -...
High telomerase RNA expression level is an adverse prognostic factor for favorable-histology Wilms' tumor. J Clin Oncol. 2005 ...https://clinicaltrials.gov/ct2/show/NCT00002611
A Study to Determine the Clinical Significance of Molecular Detection of Breast Cancer in the Blood of Stage IV Breast Cancer...
Soria JC, Gauthier LR, Raymond E, Granotier C, Morat L, Armand JP, Boussin FD, Sabatier L. Molecular detection of telomerase- ...https://clinicaltrials.gov/ct2/show/NCT00355316?term=Breast+Cancer&lup_s=12%2F17%2F2012&lup_d=30