Some targeted therapeutic drugs such as small molecular inhibitors or antibodies, that can specifically target and suppress ... Relatively large nanoparticles (NPs) can be designed to avoid invading capillaries, while small enough NPs can be used to avoid ... thereby increasing the concentration of drug in tumor sites [35]. Overall, the principles of design need to consider ... selecting and designing appropriate functional nanomedicines is essential to potentiate the antitumor immune efficacy by ...