Contraction of the type I IFN locus and unusual constitutive expression of IFN-α in bats | PNAS
... a single copy of IFN-κ was found on a separate scaffold in the P. alecto genome (scaffold 14). The pattern of a single copy of ... IFN-α genes with incomplete IFN-αR1 or IFN-αR2 binding domains were classified as IFN pseudogenes. Four bat IFN-αPs have full- ... domain prediction was further performed by using the National Center for Biotechnology Information (NCBI) Web conserved domain ... IFN-α and IFN-β proteins bind to the IFN-αR and trigger the phosphorylation of STAT1 and STAT2, which then forms a ternary ...