Frontiers | Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function
B) Binding affinities of single (JQ1) and tandem (AZD5153) BET inhibitors previously determined in a Fluorescent polarization ( ... Bromodomains are proteins that contain modules of ~110 amino acids that recognize and bind acetylated lysine residues in ... antibodies. The ChIP experiment was then performed for each antibody as described previously by Orlando et al. (24). Next, ... A) Domain organization of BET (BRD2,3,4) proteins highlighting the N-terminal tandem bromodomain (BRD) modules, the Extra- ...
Frontiers | Plant 3' Regulatory Regions From mRNA-Encoding Genes and Their Uses to Modulate Expression
In addition, after transcription, a wide array of RNA-binding proteins interacts with cis-acting elements located mainly in the ... In addition, after transcription, a wide array of RNA-binding proteins interacts with cis-acting elements located mainly in the ... Expression and Characterization of a Recombinant Single-Domain Monoclonal Antibody Against MUC1 Mucin in Tobacco Plants. ... but functions as a scaffold to preorganize two other subunits, CPSF30 and WDR33, which synergistically bind to the hexamer with ...