*  A requirement for wild-type Ras isoforms in mutant KRas-driven signalling and transformation | Biochemical Journal
Department of Protein Chemistry, Department of Bioinformatics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, U.S.A. ... A requirement for wild-type Ras isoforms in mutant KRas-driven signalling and transformation. Carolyn Bentley, Stefanie S. ... Department of Protein Chemistry, Department of Bioinformatics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, U.S.A. ... Department of Protein Chemistry, Department of Bioinformatics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, U.S.A. ...
  http://www.biochemj.org/content/452/2/313
*  TIBBS » NCI Ras Initiative: Let's get together and drug RAS!
Why is it so difficult to design a drug for RAS? Well, RAS proteins are small GTPases that cycle between an "on" state when ... Today, we know that activating mutations in the three RAS isoforms, N-RAS, H-RAS, and K-RAS, are present in nearly one-third of ... Now that you know more about the complexity of cancer, RAS proteins, and mutant RAS, aid the enhancement of public science ... to extend the knowledge base surrounding RAS proteins in cancer and to strategize methods for targeting these proteins. The ...
  http://tibbs.unc.edu/nci-ras-initiative-lets-get-together-and-drug-ras/
*  OriGene - KRAS (NM 004985) Human ORF cDNA Clone
RAS, RHO, RAB. Gene Summary: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein ... Protein Families:. Druggable Genome. Protein Pathways:. MAPK signaling pathwayErbB signaling pathwayChemokine signaling pathway ... Synonyms: C-K-RAS; c-Ki-ras2; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KI-RAS; KRAS1; KRAS2; NS; NS3; RALD; RefSeq Size: 5312 ... The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ...
  http://www.origene.com/orf_clone/Search/retrieve_results.mspx?sku=RC400114
*  Ras subfamily - Wikipedia
Ras is a family of related proteins which is expressed in all animal cell lineages and organs. All Ras protein family members ... Activating mutations of the Ras protein and upstream elements of the Ras protein may play a role in more than two-thirds of all ... RRAS2 Mutations in the Ras family of proto-oncogenes (comprising H-Ras, N-Ras and K-Ras) are very common, being found in 20% to ... Ras is a G protein, or a guanosine-nucleotide-binding protein. Specifically, it is a single-subunit small GTPase, which is ...
  https://en.wikipedia.org/wiki/Ras_subfamily
*  ras protein Protein Superfamily Detail
... ras protein. ID: PIRSF037165 Mouse Protein Superfamily Annotations. Select one or more mouse PIRSF members to download protein ... MGI protein superfamily detail pages represent the protein classification set for a homeomorphic superfamily from the Protein ... The number of protein sequences returned does not always match the numbers of homologs shown, because the same protein sequence ... You can also "Select all" mouse superfamily members to obtain their protein sequences and the protein sequences for all mouse, ...
  http://www.informatics.jax.org/vocab/pirsf/PIRSF037165
*  ras Proteins Summary Report | CureHunter
... monomeric GTP-binding proteins encoded by ras genes (GENES, RAS). The protooncogene-derived protein, PROTO-ONCOGENE PROTEIN P21 ... The oncogene-derived protein (ONCOGENE PROTEIN P21(RAS)) can play a role in aberrant cellular regulation during neoplastic cell ... RAS), plays a role in normal cellular growth, differentiation and development. ... ras Proteins. Subscribe to New Research on ras Proteins Small, monomeric GTP-binding proteins encoded by ras genes (GENES, RAS ...
  http://www.curehunter.com/public/keywordSummaryD018631-ras-Proteins.do
*  Recombinant Human Ras protein (ab61239) References | Abcam
References for Abcam's Recombinant Human Ras protein (ab61239). Please let us know if you have used this product in your ... Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Ras Family ... Proteins and Peptides. Proteomics tools. Agonists, activators, antagonists and inhibitors. Lysates. Multiplex miRNA assays. By ...
  http://www.abcam.com/recombinant-human-ras-protein-ab61239-references.html
*  Are All RAS Proteins Created Equal in Cancer? - National Cancer Institute
Different cancers seem to be preferentially driven by differnt mutations in RAS genes. Channing Der discusses what mechanisms ... The three human RAS genes encode four highly related RAS proteins (82-90% sequence identity), with alternative gene splicing ... distinct anti-RAS strategies will be needed for effective inhibition of each RAS protein. Here we review the mutational ... rather than a requirement for activation of a specific RAS protein, is a basis for RAS isoform preference in cancer induction ...
  https://www.cancer.gov/research/key-initiatives/ras/ras-central/blog/2014/ras-proteins-created-equal
*  RAS proteins | definition of RAS proteins by Medical dictionary
RAS proteins explanation free. What is RAS proteins? Meaning of RAS proteins medical term. What does RAS proteins mean? ... Looking for online definition of RAS proteins in the Medical Dictionary? ... RAS proteins , definition of RAS proteins by Medical dictionary https://medical-dictionary.thefreedictionary.com/RAS+proteins ... RAS. (redirected from RAS proteins). Also found in: Dictionary, Thesaurus, Encyclopedia. RAS. Abbreviation for reticular ...
  http://medical-dictionary.thefreedictionary.com/RAS+proteins
*  Abundant expression of ras proteins in Aplysia neurons. | JCB
Abundant expression of ras proteins in Aplysia neurons.. M E Swanson, A M Elste, S M Greenberg, J H Schwartz, T H Aldrich, M E ... Abundant expression of ras proteins in Aplysia neurons.. M E Swanson, A M Elste, S M Greenberg, J H Schwartz, T H Aldrich, M E ... and which therefore is likely to encode a ras-like Aplysia protein. The cloned locus, designated Apl-ras, is distinct from the ... The prominence of ras protein in neurons, which are terminally differentiated and non-proliferating, indicates that the control ...
  http://jcb.rupress.org/content/103/2/485
*  RAS p21 protein activator 1 - Wikipedia
RAS p21 protein activator 1 or RasGAP (Ras GTPase activating protein), also known as RASA1, is a 120-kDa cytosolic human ... Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in ... 1997). "Ras-GTPase activating protein (GAP): a putative effector for Ras". Cell. Signal. 9 (2): 153-8. doi:10.1016/S0898-6568( ... Ger M, Zitkus Z, Valius M (October 2011). "Adaptor protein Nck1 interacts with p120 Ras GTPase-activating protein and regulates ...
  https://en.wikipedia.org/wiki/RAS_p21_protein_activator_1
*  Ras protein | definition of Ras protein by Medical dictionary
Ras protein explanation free. What is Ras protein? Meaning of Ras protein medical term. What does Ras protein mean? ... Looking for online definition of Ras protein in the Medical Dictionary? ... Related to Ras protein: GTPase, G protein Ras protein. or ras protein. (răs). n.. Any of a group of proteins that are found ... Ras protein , definition of Ras protein by Medical dictionary https://medical-dictionary.thefreedictionary.com/Ras+protein ...
  http://medical-dictionary.thefreedictionary.com/Ras+protein
*  Rasgrf2 MGI Mouse Gene Detail - MGI:109137 - RAS protein-specific guanine nucleotide-releasing factor 2
RASGRF2, Ras protein specific guanine nucleotide releasing factor 2. Orthology source: HomoloGene, HGNC ... IPR001895 Ras guanine-nucleotide exchange factors catalytic domain. IPR000651 Ras-like guanine nucleotide exchange factor, N- ... IPR019804 Ras guanine-nucleotide exchange factor, conserved site. IPR023578 Ras guanine nucleotide exchange factor domain ... IPR036964 Ras guanine-nucleotide exchange factor catalytic domain superfamily. ...
  http://www.informatics.jax.org/marker/MGI:109137
*  Activation Of A Ras Protein By A Gef Protein Stock Video & More Clips of Cancer - Illness 973932842 | iStock
Download this Activation Of A Ras Protein By A Gef Protein video now. And search more of iStock's library of royalty-free stock ... Activation of a Ras protein by a GEF protein - Stock video. .... Cell Membrane, Molecule, Oncogene, Germany, Cancer - Illness. ...
  https://www.istockphoto.com/gb/video/activation-of-a-ras-protein-by-a-gef-protein-gm973932842-264977183
*  Enhancement of the GDP-GTP exchange of RAS proteins by the carboxyl-terminal domain of SCD25 | Science
This protein fragment had a similar effect on the human c-H-ras-encoded p21 protein. Thus, the SCD25 carboxyl-terminal domain ... Enhancement of the GDP-GTP exchange of RAS proteins by the carboxyl-terminal domain of SCD25 ... Enhancement of the GDP-GTP exchange of RAS proteins by the carboxyl-terminal domain of SCD25 ... Enhancement of the GDP-GTP exchange of RAS proteins by the carboxyl-terminal domain of SCD25 ...
  http://science.sciencemag.org/content/248/4957/866
*  Inhibition of non-Ras protein farnesylation reduces in-stent restenosis - Strathprints
Inhibition of non-Ras protein farnesylation reduces in-stent restenosis. Atherosclerosis, 197 (2). pp. 515-523. ISSN 0021-9150 ... mitogen-activated protein kinase 1, mitogen-activated protein kinase 3, muscle cells, muscle, smooth, vascular, ... Ras has a key role in relation to cell proliferation, survival and migration and requires farnesylation for full activity. The ... In human VSM cells FPT III (25 μM) inhibited FCS-stimulated cell proliferation through a ras-dependent mechanism (after 18 h ...
  https://strathprints.strath.ac.uk/4943/
*  GTPase-activator protein for Ras-like GTPase - Wikipedia
GTPase-activator protein for Ras-like GTPase is a family of evolutionarily related proteins. Ras proteins are membrane- ... As it is the GTP bound form of ras which is active, these proteins are said to be down-regulators of ras. The Ras GTPase- ... Note: There are distinctly different GAPs for the rap and rho/rac subfamilies of ras-like proteins (reviewed in reference) that ... This intrinsic GTPase activity of ras is stimulated by a family of proteins collectively known as 'GAP' or GTPase-activating ...
  https://en.wikipedia.org/wiki/GTPase-activator_protein_for_Ras-like_GTPase
*  Application of the Multiple Solvent Crystal Structures Method to Analyze the Protein Binding Surface of H-Ras Protein
Ras proteins participate in multiple protein : protein interactions in the cell, making Ras a good candidate protein to extend ... MSCS analysis of Ras identifies the known Ras-effector binding domain as a site of protein: protein interaction and predicts a ... H-Ras is a member of the small, monomeric GTPase protein superfamily. H-Ras functions as a 'molecular switch', using nucleotide ... Application of the Multiple Solvent Crystal Structures Method to Analyze the Protein Binding Surface of H-Ras Protein. Show ...
  https://repository.lib.ncsu.edu/handle/1840.16/5664
*  Increased K-Ras Protein and Activity in Mouse and Human Lung Epithelial Cells at Confluence -- Kammouni et al. 13 (9): 441 --...
Increased K-Ras Protein and Activity in Mouse and Human Lung Epithelial Cells at Confluence Wafa Kammouni1, Gayatri Ramakrishna ... In sum, increased protein expression and activity of K-ras p21 are associated with growth arrest, not with proliferation, in ... Although K-ras is frequently mutated in lung adenocarcinomas, the normal function of K-ras p21 in lung is not known. In two ... In all three cell types, total K-ras p21 increased 2- to 4-fold at confluence, and active K-ras p21-GTP increased 10- to 200- ...
  http://cgd.aacrjournals.org/cgi/content/abstract/13/9/441
*  Rap1b MGI Mouse Gene Detail - MGI:894315 - RAS related protein 1b
View mouse Rap1b Chr10:117814597-117845974 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression
  http://www.informatics.jax.org/marker/MGI:894315
*  RCSB PDB - Protein Feature View - Ras-related protein Rab-6B - Q9NRW1 (RAB6B HUMAN)
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex ... This protein in other organisms (by gene name): Q9NRW1 - Homo sapiens 3 * D3DND3 - Homo sapiens no matching PDB entries ... Protein disorder predictions are based on JRONN (Troshin, P. and Barton, G. J. unpublished), a Java implementation of RONN * ... The Protein Feature View requires a browser that supports SVG (Scalable Vector Graphics). Mouse over tracks and labels for more ...
  http://www.rcsb.org/pdb/protein/Q9NRW1
*  RCSB PDB - Protein Feature View - Ras-related protein Rab-14 - P61106 (RAB14 HUMAN)
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex ... Protein Feature View of PDB entries mapped to a UniProtKB sequence * Number of PDB entries for Q5JVD4: no matching PDB entries ... This protein in other organisms (by gene name): Q5JVD4 - Homo sapiens 0 * Q6Q7K5 - Homo sapiens no matching PDB entries ... Protein disorder predictions are based on JRONN (Troshin, P. and Barton, G. J. unpublished), a Java implementation of RONN * ...
  http://www.rcsb.org/pdb/protein/Q5JVD4
*  RCSB PDB - Protein Feature View - Ras-related protein Rab-18 - Q9NP72 (RAB18 HUMAN)
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex ... This protein in other organisms (by gene name): Q9NP72 - Homo sapiens 1 * P35293 - Mus musculus no matching PDB entries ... Protein disorder predictions are based on JRONN (Troshin, P. and Barton, G. J. unpublished), a Java implementation of RONN * ... The Protein Feature View requires a browser that supports SVG (Scalable Vector Graphics). Mouse over tracks and labels for more ...
  http://www.rcsb.org/pdb/protein/Q9NP72
*  RAB14 - Ras-related protein Rab-14 - Homo sapiens (Human) - RAB14 gene & protein
Ras-related protein Rab-14Add BLAST. 214. Amino acid modifications. Feature key. Position(s). DescriptionActions. Graphical ... Protein. Similar proteins. Organisms. Length. Cluster ID. Cluster name. Size. P61106. Q5ZKU5. Q91V41. Q5R8Z8. A0A024R845. ... Protein. Similar proteins. Organisms. Length. Cluster ID. Cluster name. Size. P61106. Q5ZKU5. Q91V41. Q5R8Z8. A0A024R845. ... Protein. Similar proteins. Organisms. Length. Cluster ID. Cluster name. Size. P61106. Q5ZKU5. Q91V41. Q5R8Z8. A0A024R845. ...
  http://www.uniprot.org/uniprot/P61106
*  Rab3d - Ras-related protein Rab-3D - Mus musculus (Mouse) - Rab3d gene & protein
Protein transport. Probably involved in vesicular traffic (By similarity). May be involved in the insulin-induced exocytosis of ... Ras-related protein Rab-3DAdd BLAST. 218. Amino acid modifications. Feature key. Position(s). DescriptionActions. Graphical ... Protein. Similar proteins. Organisms. Length. Cluster ID. Cluster name. Size. P35276. Q543Q4. Q8BP17. Mus musculus (Mouse). 219 ... to allow unambiguous identification of a protein.,p>,a href='/help/protein_names' target='_top'>More...,/a>,/p>Protein namesi. ...
  http://www.uniprot.org/uniprot/P35276