ral Guanine Nucleotide Exchange Factor / genetics * ral Guanine Nucleotide Exchange Factor / metabolism ...
2000). "RalGEF2, a pleckstrin homology domain containing guanine nucleotide exchange factor for Ral". J. Biol. Chem. 275 (38): ... Hattula K, Furuhjelm J, Arffman A, Peränen J (2003). "A Rab8-specific GDP/GTP exchange factor is involved in actin remodeling ...
"Ras-related protein Ral-A" and "Ras-related protein Ral-B", generically named Ral-guanine nucleotide exchange factors (RalGEF ... Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral- ... Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases ( ... Moreover, in vitro guanine nucleotide exchange assays confirm that hRgr promotes Ral and Ras activation through GDP ...
Blanke, S.; Jaeckle, H.: Novel guanine nucleotide exchange factor GEFmeso of Drosophila melanogaster interacts with Ral and Rho ... Matyash, A.; Chung, H. R.; Jaeckle, H.: Genome-wide mapping of in vivo targets of the Drosophila transcription factor Krüppel. ... Misexpression screen in Drosophila melanogaster aiming to reveal novel factors involved in formation of body parts. Genetics ...
The activation process is executed by guanine nucleotide exchange factors, while inactivation is mediated by GTPase-activating ... Ral GTPases are activated downstream of Ras and play a crucial role in the development and progression of PDAC. However, the ... Ral GTPase-activating protein regulates the malignancy of pancreatic ductal adenocarcinoma. Yoshimachi, Shingo; Shirakawa, ... In the ING4 deficient cells, histone H3K9 acetylation and the key rRNA transcription factor UBF at the promoter of rDNA were ...
Downstream signalling is controlled by both RAS-intrinsic GTP hydrolysis, guanine nucleotide exchange factors (GEFs) that ... RAL) pathways [1]. Activation leads to cell proliferation, differentiation and inhibition of apoptosis. ...
On epidermal growth factor (EGF) stimulation, activated Ras recruits guanine nucleotide exchange factors (GEFs) for RalA, ... Sec5, an integral component of the exocyst, has been shown to be a direct target for activated Ral GTPases. Ral GTPases ... Sjolinder, M., Uhlmann, J. and Ponsting, H. (2002). DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, ... In order to identify the function of deafness locus putative guanine nucleotide exchange factor (DelGEF), a protein homologous ...
Identification and Characterization of a New Family of Guanine Nucleotide Exchange Factors for the Ras-related GTPase Ral. J. ... This GDP/GTP cycling is tightly controlled by two main classes of regulatory proteins: guanine-nucleotide-exchange factors ( ... Jun, J.E.; Rubio, I.; Roose, J.P. Regulation of ras exchange factors and cellular localization of ras activation by lipid ... Among them, Raf/MEK/ERK, PI3K/AKT, and Ral are the best understood. Further, Ras crosslinks with other signaling pathways such ...
Ras is activated by guanine nucleotide exchange factors (GEFs) that release GDP and allow GTP binding. Many RasGEFs have been ... Ral, Rheb, Rhes, ARHI, RERG, Rin/Rit, RSR1, RRP22, Ras2, Ras-dva, and RGK proteins. Ras proteins regulate cell growth, ... These are sequestered in the cytosol until activation by growth factors triggers recruitment to the plasma membrane or Golgi, ...
... and Ral guanine nucleotide exchange factors (Ral-GEFs) [38] and plays an important role in multistep carcinogenesis in EC [39, ... Obesity, nulliparity, late menopause, diabetes, and use of tamoxifen are the best-known risk factors of EC, which can be ... After adjusting for these factors, the expression of EP3 in the overall cohort was showed to be an independent prognostic ... Human endometrial carcinoma cells release factors which inhibit the growth of normal epithelial cells in culture. Cell Biol ...
Ral GTPase activating protein catalytic.... RAPGEF2. 9693. RAPGEF2. Rap guanine nucleotide exchange factor .... ... TFT: Transcription Factor Targets TFT:GTRD: GTRD TFT:TFT_LEGACY: TFT_Legacy C4: Computational CGN: Cancer Gene Neighborhoods CM ... Rac/Cdc42 guanine nucleotide exchange f.... ARL6IP6. 151188. ARL6IP6. ADP ribosylation factor like GTPase 6 i.... ...
Rap1 and R-Ras guanine nucleotide exchange factor. J Biol Chem. 2000; 275:30118-23. [PMID: 10896938] ... Gotoh T, Cai D, Tian X, Feig L, Lerner A. p130Cas regulates the activity of AND-34, a novel Ral, ... Cai D, Iyer A, Felekkis K, Near R, Luo Z, Chernoff J, Albanese C, Pestell RG, Lerner A. AND-34/BCAR3, a GDP exchange factor ... Cai D, Felekkis KN, Near RI, ONeill GM, van Seventer JM, Golemis EA, Lerner A. The GDP exchange factor AND-34 is expressed in ...
... ral Guanine Nucleotide Exchange Factor D12.776.402.300.600 Ranavirus B4.909.204.490.700 Random Amplified Polymorphic DNA ... Guanine Nucleotide Exchange Factors D12.776.402.300 Guanine Nucleotide-Releasing Factor 2 D12.776.402.300.300 Gulf War I1.880. ... rho Guanine Nucleotide Dissociation Inhibitor gamma D12.776.402.225.500.300 Rho Guanine Nucleotide Exchange Factors D12.776. ... ras Guanine Nucleotide Exchange Factors D12.776.402.300.700 ras-GRF1 D12.776.402.300.700.500 Rat-Bite Fever C1.252.400.388.750 ...
... ral Guanine Nucleotide Exchange Factor D12.776.402.300.600 Ranavirus B4.909.204.490.700 Random Amplified Polymorphic DNA ... Guanine Nucleotide Exchange Factors D12.776.402.300 Guanine Nucleotide-Releasing Factor 2 D12.776.402.300.300 Gulf War I1.880. ... rho Guanine Nucleotide Dissociation Inhibitor gamma D12.776.402.225.500.300 Rho Guanine Nucleotide Exchange Factors D12.776. ... ras Guanine Nucleotide Exchange Factors D12.776.402.300.700 ras-GRF1 D12.776.402.300.700.500 Rat-Bite Fever C1.252.400.388.750 ...
... ral Guanine Nucleotide Exchange Factor D12.776.402.300.600 Ranavirus B4.909.204.490.700 Random Amplified Polymorphic DNA ... Guanine Nucleotide Exchange Factors D12.776.402.300 Guanine Nucleotide-Releasing Factor 2 D12.776.402.300.300 Gulf War I1.880. ... rho Guanine Nucleotide Dissociation Inhibitor gamma D12.776.402.225.500.300 Rho Guanine Nucleotide Exchange Factors D12.776. ... ras Guanine Nucleotide Exchange Factors D12.776.402.300.700 ras-GRF1 D12.776.402.300.700.500 Rat-Bite Fever C1.252.400.388.750 ...
... ral Guanine Nucleotide Exchange Factor D12.776.402.300.600 Ranavirus B4.909.204.490.700 Random Amplified Polymorphic DNA ... Guanine Nucleotide Exchange Factors D12.776.402.300 Guanine Nucleotide-Releasing Factor 2 D12.776.402.300.300 Gulf War I1.880. ... rho Guanine Nucleotide Dissociation Inhibitor gamma D12.776.402.225.500.300 Rho Guanine Nucleotide Exchange Factors D12.776. ... ras Guanine Nucleotide Exchange Factors D12.776.402.300.700 ras-GRF1 D12.776.402.300.700.500 Rat-Bite Fever C1.252.400.388.750 ...
... ral Guanine Nucleotide Exchange Factor D12.776.402.300.600 Ranavirus B4.909.204.490.700 Random Amplified Polymorphic DNA ... Guanine Nucleotide Exchange Factors D12.776.402.300 Guanine Nucleotide-Releasing Factor 2 D12.776.402.300.300 Gulf War I1.880. ... rho Guanine Nucleotide Dissociation Inhibitor gamma D12.776.402.225.500.300 Rho Guanine Nucleotide Exchange Factors D12.776. ... ras Guanine Nucleotide Exchange Factors D12.776.402.300.700 ras-GRF1 D12.776.402.300.700.500 Rat-Bite Fever C1.252.400.388.750 ...
ral Guanine Nucleotide Exchange Factor. *ras Guanine Nucleotide Exchange Factors. *Rho Guanine Nucleotide Exchange Factors ... "Guanine Nucleotide Exchange Factors" by people in this website by year, and whether "Guanine Nucleotide Exchange Factors" was a ... Guanine Nucleotide Exchange Factors*Guanine Nucleotide Exchange Factors. *Guanine-Nucleotide-Releasing Factor ... "Guanine Nucleotide Exchange Factors" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, ...
FACTOR DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAL. RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR. FATOR RAL DE TROCA DO NUCLEOTÍDIO ... GUANINE NUCLEOTIDE EXCHANGE FACTORS. FATORES DE TROCA DO NUCLEOTÍDIO GUANINA. FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAS ... RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS. FATORES RAS DE TROCA DE NUCLEOTÍDIO GUANINA. ... PEPTIDE ELONGATION FACTOR 2. FATOR 2 DE ELONGAÇÃO DE PEPTÍDIOS. FACTOR 2 LIBERADOR DE GUANINA NUCLEOTIDO. GUANINE NUCLEOTIDE- ...
PROTEÍNAS RAL DE LIGAÇÃO A GTP RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR FACTOR DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAL FATOR RAL ... RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAS FATORES RAS DE TROCA DE NUCLEOTÍDIO ... GUANINE NUCLEOTIDE EXCHANGE FACTORS FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO FATORES DE TROCA DO NUCLEOTÍDIO GUANINA ... GUANINE NUCLEOTIDE-RELEASING FACTOR 2 FACTOR 2 LIBERADOR DE GUANINA NUCLEOTIDO FATOR 2 DE LIBERAÇÃO DO NUCLEOTÍDIO GUANINA ...
PROTEÍNAS RAL DE LIGAÇÃO A GTP RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR FACTOR DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAL FATOR RAL ... RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAS FATORES RAS DE TROCA DE NUCLEOTÍDIO ... GUANINE NUCLEOTIDE EXCHANGE FACTORS FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO FATORES DE TROCA DO NUCLEOTÍDIO GUANINA ... GUANINE NUCLEOTIDE-RELEASING FACTOR 2 FACTOR 2 LIBERADOR DE GUANINA NUCLEOTIDO FATOR 2 DE LIBERAÇÃO DO NUCLEOTÍDIO GUANINA ...
FACTOR DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAL. RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR. FATOR RAL DE TROCA DO NUCLEOTÍDIO ... GUANINE NUCLEOTIDE EXCHANGE FACTORS. FATORES DE TROCA DO NUCLEOTÍDIO GUANINA. FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAS ... RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS. FATORES RAS DE TROCA DE NUCLEOTÍDIO GUANINA. ... PEPTIDE ELONGATION FACTOR 2. FATOR 2 DE ELONGAÇÃO DE PEPTÍDIOS. FACTOR 2 LIBERADOR DE GUANINA NUCLEOTIDO. GUANINE NUCLEOTIDE- ...
PROTEÍNAS RAL DE LIGAÇÃO A GTP RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR FACTOR DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAL FATOR RAL ... RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAS FATORES RAS DE TROCA DE NUCLEOTÍDIO ... GUANINE NUCLEOTIDE EXCHANGE FACTORS FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO FATORES DE TROCA DO NUCLEOTÍDIO GUANINA ... GUANINE NUCLEOTIDE-RELEASING FACTOR 2 FACTOR 2 LIBERADOR DE GUANINA NUCLEOTIDO FATOR 2 DE LIBERAÇÃO DO NUCLEOTÍDIO GUANINA ...
FACTOR NEUROTROFICO CILIAR FATOR RAL DE TROCA DO NUCLEOTÍDIO GUANINA RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR FACTOR DE ... GUANINE NUCLEOTIDE-RELEASING FACTOR 2 FACTOR 2 LIBERADOR DE GUANINA NUCLEOTIDO FATOR DE CRESCIMENTO NEURAL NERVE GROWTH FACTOR ... GUANINE NUCLEOTIDE EXCHANGE FACTORS FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO FATORES RAS DE TROCA DE NUCLEOTÍDIO GUANINA ... RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAS ...
PROTEÍNAS RAL DE LIGAÇÃO A GTP RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR FACTOR DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAL FATOR RAL ... RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO RAS FATORES RAS DE TROCA DE NUCLEOTÍDIO ... GUANINE NUCLEOTIDE EXCHANGE FACTORS FACTORES DE INTERCAMBIO DE GUANINA NUCLEOTIDO FATORES DE TROCA DO NUCLEOTÍDIO GUANINA ... GUANINE NUCLEOTIDE-RELEASING FACTOR 2 FACTOR 2 LIBERADOR DE GUANINA NUCLEOTIDO FATOR 2 DE LIBERAÇÃO DO NUCLEOTÍDIO GUANINA ...
regulatory factor X5 [Source:HGNC Symb.... RGL2. 5863. RGL2. ral guanine nucleotide dissociation st.... ... Rap guanine nucleotide exchange factor.... RASSF8. 11228. RASSF8. Ras association domain family member 8.... ... TFT: Transcription Factor Targets TFT:GTRD: GTRD TFT:TFT_LEGACY: TFT_Legacy C4: Computational 3CA: Curated Cancer Cell Atlas ... TCF-1 is an HMG family transcription factor which is known to be critical for T cell development. We discovered that it has a ...
ral GDP Dissociation Stimulator use ral Guanine Nucleotide Exchange Factor ral GDS use ral Guanine Nucleotide Exchange Factor ... ras Guanine Nucleotide Exchange Factor use ras Guanine Nucleotide Exchange Factors ras Guanine Nucleotide Exchange Factors ... ral Protein use ral GTP-Binding Proteins ral-GDS use ral Guanine Nucleotide Exchange Factor ... ras GEF use ras Guanine Nucleotide Exchange Factors ras GEFs use ras Guanine Nucleotide Exchange Factors ...
Age and the high mRNA expression of ARL9 were independent risk factors for a poor prognosis in patients with colon ... Like other members of the RAS superfamily, ARF family proteins can be activated by guanine-nucleotide exchange factors (GEFs) ... Yan C, Theodorescu D. RAL GTPases: biology and potential as therapeutic targets in cancer. Pharmacol Rev. 2018;70(1):1-11. ... Table 1 COX regression analysis of risk factors associated with prognosis in patients with colon adenocarcinoma. Full size ...
Additional assays for small GTPases including Rho, Ras, Cdc42, Rac, Ral, Arf also available in pull-down and G-LISA formats. ... Molecular cloning and sequencing of bovine leukemia-associated guanine nucleotide exchange factor. BMC Biochemistry. 2006. ISSN ... Dosage-dependent regulation of VAV2 expression by steroidogenic factor-1 drives adrenocortical carcinoma cell invasion. Science ...
HUMAN Rho guanine nucleotide exchange factor 15 OS=Homo sapiens OX=9606 GN=ARHGEF15 PE=1 SV=4 ... HUMAN Ras-related protein Ral-A OS=Homo sapiens OX=9606 GN=RALA PE=1 SV=1 ... HUMAN Rho guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=ARHGEF1 PE=1 SV=2 ... HUMAN Rho guanine nucleotide exchange factor 26 OS=Homo sapiens OX=9606 GN=ARHGEF26 PE=1 SV=4 ...