5.11 Increased International Normalized Ratio (INR)/Prolonged Prothrombin Time 5.12 Development of Drug-Resistant Bacteria 6 ... Increased International Normalized Ratio (INR)/Prolonged Prothrombin Time [see Warnings and Precautions (5.11) and Drug ... 5.11 Increased International Normalized Ratio (INR)/Prolonged Prothrombin Time. Clinically relevant plasma concentrations of ... of daptomycin have been observed to cause a significant concentration-dependent false prolongation of prothrombin time (PT) and ...

Prothrombin times should be carefully monitored while patients are receiving azithromycin and oral anticoagulants concomitantly ... Warfarin: Use with azithromycin may increase coagulation times; monitor prothrombin time. (7.2) ... although the prothrombin time was not affected in the dedicated drug interaction study with azithromycin and warfarin. ...

PT = Prothrombin Time. QD = once daily. TID = three times daily. Metformin. 850 mg TID. 10 mg QD. metformin. 1.01. 0.89. ...

Prothrombin times should be carefully monitored while patients are receiving azithromycin and oral anticoagulants concomitantly ... Warfarin: Use with azithromycin may increase coagulation times; monitor prothrombin time. ( 7.2) ... although the prothrombin time was not affected in the dedicated drug interaction study with azithromycin and warfarin. ...

Carvedilol (12.5 mg twice daily) did not have an effect on the steady-state prothrombin time ratios and did not alter the ...

Prothrombin Time Significantly Increased. If patients receiving coumarin preparations are treated simultaneously with ... significantly increased maximum prothrombin time by approximately 2 times that of placebo in healthy subjects [see Drug ... voriconazole, the prothrombin time or other suitable anticoagulation tests should be monitored at close intervals and the ...

Effect on Prothrombin Time Alterations in prothrombin times have occurred in patients treated with ceftriaxone. Monitor ... may be necessary if the prothrombin time is prolonged before or during therapy. ... a decrease in the prothrombin time, renal precipitations, seizures, and serum sickness ... prothrombin time during ceftriaxone treatment in patients with impaired vitamin K synthesis or low vitamin K stores (e.g., ...

Effect on Prothrombin Time Alterations in prothrombin times have occurred in patients treated with ceftriaxone for injection. ... Monitor prothrombin time during ceftriaxone for injection treatment in patients with impaired vitamin K synthesis or low ... may be necessary if the prothrombin time is prolonged before or during therapy. ... a decrease in the prothrombin time, renal precipitations, seizures, and serum sickness. ...

Increases in INR and prothrombin time may lead to abnormal bleeding and even death [see Warnings and Precautions (5.2)]. ... Monitor INR and prothrombin time. Dose adjustment of warfarin may be needed to maintain target INR range. See prescribing ... There have been reports of increased INR and prothrombin time in patients receiving a proton pump inhibitor and warfarin ... Increases in INR and prothrombin time may lead to abnormal bleeding and even death. Patients treated with rabeprazole sodium ...

Change in mean prothrombin time. ↑17%. ↑0.4 sec. ↑15%. 20 mg OD for 9 days ...

Prothrombin time/international normalized ratio. Activated partial thromboplastin time. Activated clotting time. Coagulation ... Coagulation test interference: Telavancin interferes with some laboratory coagulation tests, including prothrombin time, ...

Mefenamic acid may prolong prothrombin time. Therefore, when the drug is administered to patients receiving oral anticoagulant ... drugs, frequent monitoring of prothrombin time is necessary.. A false-positive reaction for urinary bile, using the diazo ...

Prothrombin time was increased by 5%. The clinical significance of these findings is unknown. ...

Prothrombin time was increased by 5%. The clinical significance of these findings is unknown. ...

No significant change in prothrombin time. †Single dose on day 5. ‡Nortriptyline is an active metabolite of amitriptyline. ...

Prothrombin time, therefore, should be monitored.. Neuroleptic Drugs: Hypotension and cardiac arrest have been reported with ... administration of propranolol and warfarin has been shown to increase warfarin bioavailability and increase prothrombin time. ...

... administration of propranolol and warfarin has been shown to increase warfarin bioavailability and increase prothrombin time. ...

Prothrombin decreased, Purpura, Thrombocythemia ...

Prothrombin time was not affected by levetiracetam. Coadministration of warfarin did not affect the pharmacokinetics of ...

Warfarin (a CYP2C9 substrate): Risk of decreased INR of prothrombin time; monitor INR in 2-week period, particularly at 7 to 10 ... In patients on chronic warfarin therapy, monitor the prothrombin time (INR) in the 2-week period, particularly at 7 to 10 days ... Decreased warfarin exposure and decreased prothrombin time (INR) [see Warnings and Precautions (5.2), Clinical Pharmacology ( ... of prothrombin time [see Clinical Pharmacology (12.3)]. Monitor the INR in patients on chronic warfarin therapy in the 2-week ...

There have been reports of altered (either increased or decreased) prothrombin times in taking both warfarin and trazodone. ...

Warfarin: Monitor prothrombin time when starting or stopping raloxifene. ( 7.2, 12.3) * Highly Protein-Bound Drugs: Use with ... Names for this test include "prothrombin time," "pro-time," or "INR." Your doctor may need to adjust the dose of your warfarin ... However, a 10% decrease in prothrombin time was observed in the single-dose study. In the osteoporosis treatment trial, there ... If raloxifene is given concomitantly with warfarin or other warfarin derivatives, prothrombin time should be monitored more ...

Prothrombin time, International Normalized Ratio (INR) or other suitable anticoagulation tests should be closely monitored if ... HEMATOPOIETIC: anemia, granulocytopenia, hemorrhage unspecified, leukopenia, prothrombin decreased, thrombocythemia, ... nor did it influence prothrombin times. (See PRECAUTIONS: Drug Interactions.) ...

Elevations of the prothrombin time in the setting of concurrent warfarin and levofloxacin use have been associated with ... Prothrombin time, International Normalized Ratio (INR), or other suitable anticoagulation tests should be closely monitored if ... or prothrombin time and clinical episodes of bleeding. Patients should notify their physician if they are taking warfarin, be ...

a. Increased prothrombin and factors VII, VIII, IX, and X; decreased antithrombin 3; increased norepinephrine-induced platelet ...

Prolonged prothrombin time was reported in one patient (2%). ...

a. Increased prothrombin and factors VII, VIII, IX and X; decreased antithrombin 3; increased norepinephrine-induced platelet ...

a. Increased prothrombin and factors VII, VIII, IX, and X; decreased antithrombin 3; increased norepinephrine-induced platelet ...

Increased prothrombin and factors VII, VIII, IX, and X; decreased antithrombin 3; increased norepinephrine-induced platelet ...

Prothrombin time should be monitored in patients at risk and exogenous vitamin K administered as indicated. ... Cephalosporins may be associated with a fall in prothrombin activity. Those at risk include patients with renal or hepatic ... prolonged prothrombin time, elevated LDH, pancytopenia, and agranulocytosis. ...