*  Abnormal Liver Parameters - What Do They Tell Us? - WSAVA2013 - VIN
Plasma Proteins. Hypoalbuminaemia can indicate reduced liver function associated with cirrhosis or PSVA. As there are quite a ... These include measurement of serum bile acid concentrations, plasma ammonia concentration and bile pigment (bilirubin) ... Ammonia needs to be measured from EDTA plasma within 1 hour after sampling. ...
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*  Management Options for Cats with Retroviral Diseases - WSAVA2008 - VIN
Plasma transfusions. Effect is transient. Risk of anaphylactic reaction with repeated transfusions. ...
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*  Veterinary Neurology and Neurosurgery Journal (VNNJ) Case Study 3 - NeuroVet - VIN
Top]. Diagnosis and Summary. The signalment, clinical signs, imaging studies and histopathology in this case were all consistent with a diagnosis of calcinosis circumscripta (also referred to as tumoral calcinosis).. Calcinosis circumscripta is an idiopathic condition which occurs as single or multiple ectopic areas of mineralization and deposition of calcium salts in periarticular connective tissue. It occurs most commonly in young, large-breed dogs, with an apparently higher incidence in German shepherd dogs. A frequent location is at the dorsal aspect of the first and second cervical vertebrae; however other locations have been reported.1-3 Neurological signs depend on the location of the mass and result from spinal cord and nerve root compression by the expanding mass. Diagnosis is made on the basis of radiographs; myelography will usually demonstrate an extradural compressive lesion. Computed tomography or magnetic resonance imaging may further delineate the lesion and be valuable in ...
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*  Veterinary Neurology and Neurosurgery Journal (VNNJ) Case Study 4 - NeuroVet - VIN
Veterinary Neurology and Neurosurgery is greatly indebted and grateful to Drs. Pesavento and Higgins for providing this pathology report. Gross Pathology. Three pieces of tissue are submitted for examination. The first is an entire brain and the second is an irregular piece of bone that is 2.0 x 4.0 x 0.2 x 0.5 cm (petrous temporal bone). The third piece is an irregularly shaped piece of firm tissue, approximately 3.0 x 2.0 x 1.5-0.5 cm This tissue is white and firm, roughly triangular in shape and expanded by a tan to white, smooth, nodular mass. On section, the nodular mass is hard, light tan with diffuse hard white foci. Multiple sections of this mass are placed in cassettes A and B. Multiple sections from rostral to the caudal cerebrum are placed into cassettes C-G. All sections are taken from the right side of the brain. The right cerebellum extending from the falx (rostral) to mid cerebellum. When sectioned, there is a hard mass encompassed by cerebellar cortex that is similar to the mass ...
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*  Veterinary Neurology and Neurosurgery Journal (VNNJ) Case Study 6 - Issue 1 - Volume 3 - Vet Neurol Neurosurg J
Right femorotibial joint aspirate: Smears (2) contain blood and abundant mucoproteinaceous background precipitate typical of synovial fluid. Estimated leucocyte count: 2,000-4,000/microliter; leucocytes are neutrophils, the majority of which are nondegenerated; no organisms seen. [Top]. Case Summary. The signalment, clinical signs, radiographic studies and joint fluid cytology in this case were all consistent with immune-mediated polyarthritis.. The clinical presentation of this case suggested an orthopedic disorder or polyarthritis. The imaging studies did not reveal erosive changes involving the articular joint surfaces. The synovial fluid cytology was also consistent with a polyarthritis. These changes in conjunction with a positive ANA serology suggest that this case fits the category of systemic lupus erythematosus of the immune-mediated polyarthropathies.. There are at least four classes of immune-mediated polyarthropathy described in the cat, including rheumatoid arthritis, progressive ...
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*  Resuscitation From Hypovolemic Shock - WSAVA2002 - VIN
Plasma COP can be maintained near normal with synthetic colloids, favoring intravascular fluid retention. ... Profound hypovolemia can result from trauma, loss of plasma water during vomiting and diarrhea, extreme venodilation from ... 2. Packed red blood cells reconstituted with isotonic saline, plasma, HES or DEX ...
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*  Plasma Creatinine for Testing Renal Function: Avoid Misinterpretation - WSAVA2002 - VIN
Anticoagulants-Plasma and serum Cr values are very similar.. Storage conditions-In total blood, Cr is stable up to 24-36 hours ... In frozen plasma or serum, the stability is excellent: after 8 months at -20°C, the decrease in Cr concentration is only 6.5 ... Plasma (or serum) creatinine (Pl-Cr) concentration is mainly measured in dogs and cats to aid diagnosis of renal dysfunction. ... 1-mL (or less) of blood is sampled just before (basal) and at 5 min, 1, 2, 6 and 10 h. The plasma clearance of Cr is then ...
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*  Drug Use in Renal Failure - WSAVA2007 - VIN
Plasma clearance of drugs eliminated by the liver may also be modified by CKD. In dogs with subclinical CKD, plasma clearance ... Plasma Protein Binding Dehydration and decrease in plasma protein binding (PPB) observed in CKD may affect the volume of ... Plasma protein binding displacement interactions-Why are they still regarded s clinically important ? Br. J. Clin. Pharmacol. ... Relationship between plasma creatinine concentration and glomerular filtration rate in dogs. J Vet Pharmacol Ther. 1995;18:418- ...
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*  Addison's Disease: What's The Best Treatment? - WSAVA2008 - VIN
Endogenous Plasma ACTH Concentration. Estimating the plasma ACTH concentration is the most reliable means of differentiating ... Although fluid therapy alone generally results in a marked reduction in plasma potassium, restoration of renal perfusion and ... In a dog with clinically significant hypoadrenocorticism this dose is likely to produce plasma cortisol concentrations of ... Because of the potential for excessively rapid correction of the hyponatraemia, plasma sodium concentration should be monitored ...
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*  Chronic Kidney Disease - WSAVA2013 - VIN
Assessment is based on the plasma/serum creatinine concentration, proteinuria and blood pressure. Plasma/serum creatinine is a ... replace plasma creatinine in such a classification scheme. ...
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*  Assessment of Renal Function: What Can Be Done In Practice - WSAVA2002 - VIN
Unfortunately, the plasma creatinine concentration is not linearly related to GFR. As the plasma concentration increases so ... Plasma creatinine is the most reliable. Its production is determined by the muscle mass of the animal. Its rate of excretion ... If plasma and urine samples are taken at the same time and phosphate and creatinine measured in both, calculation of the ... Cats often lose muscle mass with age and a plasma creatinine concentration at the top end of the reference range in an old cat ...
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*  Clinical Assessment of Renal Function: New Methods, Old Ideas - WSAVA 2003 Congress - VIN
Clearance from plasma of a variety of substances, such as iohexol, determined from serial determinations of plasma ... Pharmacokinetic models are then employed to estimate GFR from calculated plasma clearance of the test substance. Plasma ... the presence of noncreatinine chromogens in the plasma of normal dogs and cats complicates interpretation of plasma ... Such techniques may provide a more reliable measure of GFR than determination of plasma concentration of creatinine and BUN, ...
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*  Pancreatitis in the Dog and Cat - WSAVA2002 - VIN
Transfusion of plasma or whole blood to replace '-macroglobulin can be life saving and has the benefit of maintaining plasma ... Plasma transfusion before intervention should be routine. A jejunostomy tube should also be placed at surgery. Nutritional ... Hetastarch can also be used if plasma is unavailable, but this only maintains blood volume and does nothing to replace ...
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*  Diseases of the Blood - WSAVA2002 - VIN
Hereditary disorders may affect any blood cells or plasma proteins. For many hereditary blood diseases, the biochemical basis ... Plasma transfusions may supplement bleeding animals with coagulopathies. Experimental allogeneic bone marrow transplantation ...
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*  Diagnostic Approach to the Incidental Adrenal Mass - WSAVA2002 - VIN
Increased plasma deoxycorticosterone and nondetectable plasma aldosterone concentrations were documented in the dog. Adrenal ... If weakness and severe hypokalemia are present, plasma aldosterone concentrations can be measured in addition to plasma ... Documenting increased plasma aldosterone concentrations prior to and after ACTH administration is used to confirm the diagnosis ... Diagnosis requires documenting an increased plasma progesterone concentration. Functional tumors producing excessive amounts of ...
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*  Current Concepts for the Management of Chronic Renal Failure in the Dog and Cat--Early Diagnosis and Supportive Care -...
Plasma Clearance Tests--GFRis defined as the mls of plasma that are cleared of a substance/min/kg body weight. Renal clearance ... By measuring the plasma or serum disappearance of iodine following a single intravenous dose of iohexol, GFR can be estimated ... The relative ease in performing plasma or serum clearance procedures, compared to urinary clearance procedures, also makes this ... Plasma was analyzed for iohexol by 3 assay methods: chemical, high-performance liquid chromatolography (HPLC), and inductively ...
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*  Biochemical Markers of Cardiac Dysfunction - WSAVA2002 - VIN
Plasma concentrations of the natriuretic peptides, ANP and BNP, also increase in patients with chronic heart failure, in ... Plasma concentration of atrial natriuretic peptide in relation to severity of mitral regurgitation in Cavalier King Charles ... recently published normal values for circulating plasma troponin I concentrations in dogs and cats. Schober et al. found ... Evaluation of plasma natriuretic peptides as markers for left ventricular dysfunction. Am Heart J 1997; 134:442-49. ...
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*  Feline Toxoplasmosis - WSAVA2013 - VIN
In acute illness, total plasma protein may be decreased. Thoracic radiographic findings can include a diffuse ...
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*  Non-Ulcerative Diseases of the Cornea - WSAVA2008 - VIN
Masses are subepithelial infiltrates of lymphocytes, plasma cells, and histiocytes. Most commonly seen in cocker spaniels, ...
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*  State of the Art: Biomarkers in Parvoviral Enteritis - WSAVA2013 - VIN
The decrease in plasma proteins through the course of the disease are mostly due to a combination of intestinal haemorrhage ... Increased plasma granulocyte colony-stimulating factor (G-CSF) concentration has been observed in CPV enteritis just after the ... Plasma lipoproteins bind the bioactive portion of the endotoxin (LPS) molecule, preventing it from stimulating monocytes, ... Effect of parvoviral enteritis on plasma citrulline concentration in dogs. J Vet Intern Med. 2011;25:215-221. ...
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*  Feline Hypertension: Diagnosis and Management - WSAVA2002 - VIN
Plasma creatinine does not change over this short time frame. This would suggest a beneficial effect on renal hemodynamics in ... One biochemical change we have observed in cats treated with amlodipine is a decrease in plasma potassium concentration and ... However, close monitoring of both SABP and plasma creatinine would be advisable following the introduction of the ACE inhibitor ... ocular lesions compatible with systemic hypertension then we would recheck the cat in 7 to 14 days and perform a routine plasma ...
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*  A Case Oriented Approach to Urinary System Laboratory Profiling in Dogs and Cats - WSAVA2008 - VIN
If BUN is elevated but urine specific gravity is isosthenuric (between 1.008 and 1.017, the concentration of plasma), then ... Consequently, serum levels will only be elevated in conditions where there is increased permeability of plasma membranes. In ... The normal specific gravity of plasma is between 1.008 and 1.012; when urine specific gravity is in this range the kidney has ... more chronic liver disease, plasma membrane permeability is often normal. Additionally, ALT levels reflect the number of ...
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