Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of ... MAPK14 interacts also with casein kinase II, leading to its activation through autophosphorylation and further phosphorylation ... Tissue specificity. Brain, heart, placenta, pancreas and skeletal muscle. Expressed to a lesser extent in lung, liver and ... Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.. Contains 1 protein kinase ...

Phosphorylated on serine upon DNA damage, probably by ATM or ATR. Serine phosphorylation is important for the formation of ... Additional screenshots of mapped reads can be downloaded here. The University of Geneva owns patents relevant to ChIC ( ... Tissue specificity. Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. ... May play an apoptotic role by transctivating BIRC5 expression under LEP activation (PubMed:18242580). Cytoplasmic STAT3 ...