Biotransformation of Dioscorea nipponica by Rat Intestinal Microflora and Cardioprotective Effects of Diosgenin
Further, our results show that diosgenin protects the myocardium against ischemic insult through increasing enzymatic and ... L. F. Wang, Y. Q. Zhao, W. Z. Gao, J. S. Lou, and Y. Kang, "Dioscorea saponins increased antioxidative ability of myocardium ... Histological Examination of Myocardium. Immediately after the sacrifice of the rats, the hearts were removed, washed with iced ... Light microscopy of heart tissue sections from normal control rat myocardium showed obvious integrity of myocardial membrane, a ...
Efficacy and Mechanism of Preoperative Simvastatin Therapy on Myocardial Protection after Extracorporeal Circulation
Simvastatin reduced the generation of autophagosomes and the ultrastructural injuries to myocardium.,i, Conclusion,/i,. ... Ultrastructure of the myocardium and autophagosomes were observed. Beclin-1, LC3-II/I, P62, AMPK, and the phosphorylation of ... Simvastatin reduced the generation of autophagosomes and the ultrastructural injuries to myocardium. Conclusion. Perioperative ... interleukin-6 (IL-6), and interleukin-8 (IL-8). Ultrastructure of the myocardium and autophagosomes were observed. Beclin-1, ...
Activation of Toll-Like Receptors and Inflammasome Complexes in the Diabetic Cardiomyopathy-Associated Inflammation
S. Ares-Carrasco, B. Picatoste, E. Camafeita et al., "Proteome changes in the myocardium of experimental chronic diabetes and ... DCM entails the damage of the myocardium through fibrosis, steatosis, apoptosis, and hypertrophy [3] and results from the ... TLRs and NLRP3 inflammasome activation in the proinflammatory myocardium. (a) Activation of TLR2 and TLR4, (b) and NLRP3 ... and successive migration of leukocytes into the myocardium [12, 13]. Migrated monocytes can further develop into tissue ...
Novel Molecular Targets Participating in Myocardial Ischemia-Reperfusion Injury and Cardioprotection
The spontaneously elevated adenosine receptor A2BR found in myocardium during MIRI may exert an infarct-limiting effect in the ... E. Mendoza-Torres, J. A. Riquelme, A. Vielma et al., "Protection of the myocardium against ischemia/reperfusion injury by ... Besides activation of mitophagy in the MIRI myocardium, inhibition of mitochondrial fission in the criminal cardiac ... MIRI develops when the effective myocardium-supporting circulation is decreased and subsequently restored, and cardiomyocyte ...
Effect Evaluation of Echocardiography on Right Ventricular Function in Patients after the Recovering from Coronavirus Disease...
The width of the custom "region of interest" included the endocardium, myocardium, and epicardium. Acoustic markers were ... of the right ventricle as well as the longitudinal and transverse systolic functions of the right ventricular myocardium. TAPSE ...
MIF mRNA Expression and Soluble Levels in Acute Coronary Syndrome
mention that upon ischaemia injury, MIF is rapidly released from the myocardium and mediates cardioprotection; however, with ...
Detection of Postcoronary Stent Complication: Utility of 64-Slice Multidetector CT
Further intervention was deferred as no viable myocardium was identified on delayed enhancement cardiac MRI. Regular followup ...
Ginkgo Biloba Extract Reduces Cardiac and Brain Inflammation in Rats Fed a HFD and Exposed to Chronic Mental Stress through NF...
... immunohistochemical staining of myocardia showing the distribution of IL-1β; scale bar: 10000 μm and 500 μm; (c) the expression ... We suggest that an imbalance of proinflammatory and anti-inflammatory signals contributes to myocardium disruption. GBE could ...
Assessment of Trimetazidine Treatment in Acute Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention
... α is related to myocardium structure and left ventricular remodeling [26-30]. Therefore, our study used CPR and TNF-α as study ... decreased the amount of infarcted myocardium (as evidenced by the CK and CKMB on the second day and of cTNI after 6 days of ... the current study examined myocardial enzymes as an indicator of the amount of infarcted myocardium. Though our study did not ...
Hemodynamic Transesophageal Echocardiography-Guided Venous-Arterial Extracorporeal Membrane Oxygenation Support in a Case of...
a) Myocardium with prominent lymphohistiocytic infiltrate and well-formed multinucleated giant cells (H&E, original ...
Effect of Bile Acid on Fetal Lung in Rat Model of Intrahepatic Cholestasis of Pregnancy
L. Liu, Y.-L. Ding, and L.-J. Wen, "Effects of maternal hypercholanemia on fetal myocardium in rats.," Chinese Journal of ...
Resveratrol Inhibits Ischemia-Induced Myocardial Senescence Signals and NLRP3 Inflammasome Activation
In this study, TUNEL staining demonstrated a high degree of myocardium apoptosis after MI surgery (Figures 5(a)-5(c)), and RSV ... The sections were incubated with 1% 2,3,5-triphenyltetrazolium chloride (TTC) solution for 20 min at 37°C. Viable myocardium ... these senescence markers were obviously downregulated in the infarcted myocardium (Figures 3(a)-3(f)). RT-PCR was performed to ... the obstruction or narrowing of arteries and arterioles resulted in inadequate supply of oxygenated blood for the myocardium [1 ...
Perioperative Dynamics of TLR2, TLR4, and TREM-1 Expression in Monocyte Subpopulations in the Setting of On-Pump Coronary...
Impaired cardiac contractility is associated with the increase in TNFα, IL-1β in the myocardium and cardiomyocyte TLR2 ... M. Nahrendorf, F. K. Swirski, E. Aikawa et al., "The healing myocardium sequentially mobilizes two monocyte subsets with ...
CYP2J2 Is a Diagnostic and Prognostic Biomarker Associated with Immune Infiltration in Kidney Renal Clear Cell Carcinoma
CYP2J2 is a member of the monooxygenase cytochrome P450 family, and it is highly expressed in the endothelium, myocardium, and ...
Membrane Omega-3 Fatty Acid Deficiency as a Preventable Risk Factor for Comorbid Coronary Heart Disease in Major Depressive...
DHA composition is highly correlated human myocardium biopsy EPA+DHA composition [97] and primate frontal gray matter biopsy ...
Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging
M. L. Springer, R. E. Sievers, M. N. Viswanathan et al., "Closed-chest cell injections into mouse myocardium guided by high- ... D. Guo, X. Li, P. Sun et al., "Ultrasound/microbubble enhances foreign gene expression in ECV304 cells and murine myocardium," ... This system was successful to target the injection of labeled cells into specific cardiac regions such as myocardium adjacent ... to ischemic area in a mouse myocardial infarction model or to treat ischemic myocardium implanting bone marrow cells and to ...
miR-409-3p Regulated by GATA2 Promotes Cardiac Fibrosis through Targeting Gpd1
In the present study, miR-409-3p was found to increase in the myocardium of post-MI mice and NRCFs treated with Ang II or TGF-β ... Myocardium specimens from sham or post-MI mice were fixed in 4% paraformaldehyde for 24 h, embedded in paraffin, and then ... S. Huang, L. Zhang, J. Song et al., "Long noncoding RNA MALAT1 mediates cardiac fibrosis in experimental postinfarct myocardium ... the myocardia were disordered, and the structures of ventricles were severely disrupted in post-MI hearts than the sham group. ...
Macrophage Plasticity in Skeletal Muscle Repair
M. Nahrendorf, F. K. Swirski, E. Aikawa et al., "The healing myocardium sequentially mobilizes two monocyte subsets with ...
Tissues Use Resident Dendritic Cells and Macrophages to Maintain Homeostasis and to Regain Homeostasis upon Tissue Injury: The...
M. Nahrendorf, F. K. Swirski, E. Aikawa et al., "The healing myocardium sequentially mobilizes two monocyte subsets with ...
CXCR4-Overexpressing Umbilical Cord Mesenchymal Stem Cells Enhance Protection against Radiation-Induced Lung Injury
Z. Cheng, L. Ou, X. Zhou et al., "Targeted migration of mesenchymal stem cells modified with CXCR4 gene to infarcted myocardium ...
Ischemic Brain Stroke and Mesenchymal Stem Cells: An Overview of Molecular Mechanisms and Therapeutic Potential
... which further trigger the functional role of MSCs in repairing the infarcted myocardium [48, 49]. Further studies have ...
The Importance of the Double Product in the Six-Minute Walk Test to Predict Myocardial Function
... of the increase of the DP during the march test seems to be a better parameter reflecting the efficiency of the myocardium from ... of the increase of the DP during the march test seems to be a better parameter reflecting the efficiency of the myocardium from ... of the increase of the DP during the march test seems to be a better parameter reflecting the efficiency of the myocardium from ... product during walking and walking distance covered seem to be the best parameter reflecting the efficiency of the myocardium. ...
Combining CT Images and Clinical Features of Four Periods to Predict Whether Patients Have Rectal Cancer
Y. Hamamichi, F. Ichida, I. Hashimoto et al., "Isolated noncompaction of the ventricular myocardium: ultrafast computed ...
Phikud Navakot Modulates the Level of Pro-Inflammatory Mediators and the Protein Expression of SOD1 and 2 and the Nrf2/HO-1...
L.-M. Yu, X. Dong, X.-D. Xue et al., "Protection of the myocardium against ischemia/reperfusion injury by punicalagin through ... injury markers and apoptotic cell death in myocardium of rats," Indian Journal of Clinical Biochemistry, vol. 30, no. 1, pp. 27 ... and infiltration of inflammatory cells in the myocardium in IMI rats [43]. Vanillic acid, as a potent free radical scavenger, ...
Bone Marrow Aspirate Concentrate-Enhanced Marrow Stimulation of Chondral Defects
A. A. Kocher, M. D. Schuster, M. J. Szabolcs et al., "Neovascularization of ischemic myocardium by human bone-marrow-derived ...
A Review on the Traditional Chinese Medicinal Herbs and Formulae with Hypolipidemic Effect
Q. Ni, J. Wang, E. Q. Li et al., "Study on the protective effect of Shengmai San on the myocardium in the type 2 diabetic ...
Mas Receptor Blockade Promotes Renal Vascular Response to Ang II after Partial Kidney Ischemia/Reperfusion in a Two-Kidney-One...
... a delay of lethal cell injury in ischemic myocardium," Circulation, vol. 74, no. 5, pp. 1124-1136, 1986. ...
Distinguishing Cardiac Amyloidosis and Hypertrophic Cardiomyopathy by Thickness and Myocardial Deformation of the Right...
Cardiac amyloidosis (CA) is defined by the presence of extracellular amyloid deposition within the myocardium of the whole ... which can be divided into the following categories according to the segments of hypertrophic myocardium: (1) interventricular ...
The Citrus Flavanone Naringenin Protects Myocardial Cells against Age-Associated Damage
"Mitochondrial function in permeabilized cardiomyocytes is largely preserved in the senescent rat myocardium," PLoS ONE, vol. 7 ...
Application Value of NT-proBNP Combined with NLR in Evaluation of Major Adverse Cardiac Events in Elderly Patients with Chronic...
... stimulates the release of BNP from the myocardium of atrial wall, and makes BNP rapidly synthesized and released into the blood ...