Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction
Mucus * NF-E2-Related Factor 2 / deficiency * NF-E2-Related Factor 2 / physiology ...
Do commonly used ventilator settings for mechanically ventilated adults have the potential to embed secretions or promote...
... that may result in mucus movement either away from the ventilator (deeper into the lungs) or toward the ventilator (toward the ... between the expiratory and inspiratory flow have been reported as thresholds for mucus movement. ...
Increased neutrophil numbers and IL-8 levels in airway secretions in acute severe asthma: Clinical and biologic significance
Mucus / cytology * Neutrophils / cytology* * Respiration, Artificial * Trachea / metabolism Substances * Inflammation Mediators ...
The influence of Flutter®VRP1 components on mucus transport of patients with bronchiectasis
... Respir Med. 2011 Sep;105(9):1316-21 ... Objective: To separately evaluate the effect of the Flutter(®)VRP1 components (high frequency oscillation and PEP) on mucus ...
A double-blind placebo controlled trial with oral ambroxol and N-acetylcysteine for mucolytic treatment in cystic fibrosis
The therapeutic efficacy of oral N-acetylcysteine (NAC) and ambroxol as compared with the effect of placebos was studied in 36 cystic fibrosis (CF) patients with mild to moderate pulmonary disease. The patients were randomly assigned to one of three regimens, matched on the basis of age and Chrispin …
Role of progestins in contraception
Cervix Mucus / drug effects * Contraception / methods* * Contraceptive Agents, Female / adverse effects * Contraceptive Agents ...
Effect of beta-adrenergic agonists on mucociliary clearance
... or mucus) fluid layer on the airway surface and ciliated cells that prop … ... or mucus) fluid layer on the airway surface and ciliated cells that propel the mucus out of the lung towards the mouth. In vivo ...
Field M[Auth] - Search Results - PubMed
Mucus sialylation determines intestinal host-commensal homeostasis. Yao Y, Kim G, Shafer S, Chen Z, Kubo S, Ji Y, Luo J, Yang W ...
Shale DJ[au] - Search Results - PubMed
Mucus hypersecretion: a common symptom, a common mechanism? Shale DJ, Ionescu AA. Shale DJ, et al. Eur Respir J. 2004 Jun;23(6 ...
Diana Lopes - Search Results - PubMed
Sea Slug Mucus Production Is Supported by Photosynthesis of Stolen Chloroplasts. Lopes D, Cruz S, Martins P, Ferreira S, Nunes ...
Anatomy, Head and Neck, Nasal Cavity - StatPearls - NCBI Bookshelf
Like the nasal cavity, the wall lining of the sinuses also secretes mucus. The cilia on the surface sweep the mucus in a carpet ... This type of epithelial lining also secretes mucus that coats the lining and helps with the mucociliary clearance of minute ... The mucus of the nasal cavity forms a protective barrier to inhaled pathogens. The components of the mucus that actively ... Like the nasal cavity, the wall lining of the sinuses also secretes mucus. The cilia on the surface sweep the mucus in a carpet ...
The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium
The distal airway contains a pseudostratified mucocilary epithelium that is defined by basal epithelial cells and mucus cells ... MUC5B-EC were the dominant mucus cell type in the HC epithelium. The distal airway epithelium from control and IPF/UIP subjects ... Methods: Immunofluorescence was used to subtype mucus cells according to MUC5B and MUC5AC expression and to identify ciliated, ... The distal airway contains a pseudostratified mucocilary epithelium that is defined by basal epithelial cells and mucus cells ...
Bautovich G[au] - Search Results - PubMed
Inhalation of dry powder mannitol improves clearance of mucus in patients with bronchiectasis. Daviskas E, Anderson SD, Eberl S ...
Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice
In particular, the abundance of the mucus-degrading bacteria Akkermansia muciniphila and Bacteroides fragilis was increased. ... Consistently, bacteria-derived mucolytic enzymes were enriched leading to erosion of the colonic mucus layer of sugar-fed wild- ...
Andelid K[au] - Search Results - PubMed
Lung macrophages drive mucus production and steroid-resistant inflammation in chronic bronchitis. Andelid K, Öst K, Andersson A ...
Nickola TJ[au] - Search Results - PubMed
Airway mucus obstruction: mucin glycoproteins, MUC gene regulation and goblet cell hyperplasia. Rose MC, Nickola TJ, Voynow JA. ...
Effects of a bicarbonate-alkaline mineral water on gastric functions and functional dyspepsia: a preclinical and clinical study
Animals then underwent pylorus ligation to evaluate gastric secretion of acid, pepsinogen, and mucus. In separate experiments, ... without changes in bound mucus. The enhancing actions of Uliveto on gastric secretions and emptying were prevented by L-365,260 ...
Identification of glycosaminoglycans in human airway secretions
... known to be present in airway mucus, are macromolecules with a variety of structural and biological functions. In the present ... Glycosaminoglycans (GAGs), known to be present in airway mucus, are macromolecules with a variety of structural and biological ... cells were used to assess their differential contribution to GAGs in mucus. Distribution was further assessed by ...
GEO Accession viewer
Genome-wide transcriptional profiles of biopsies from the MUCUS trial. GSE97510. Epithelial-mesenchymal transition in cancer ...
Remodeling in asthma and chronic obstructive lung disease
The hypertrophy of submucosal mucus-secreting glands is similar in extent in asthma and COPD. The number of bronchial vessels ...
GPL16791[Accession] - GEO DataSets - NCBI
MicroRNAs in Nasal Lavage Extracellular Vesicles as Potential Therapeutic Targets for Mucus Hypersecretion ...
Sharma D[au] - Search Results - PubMed
Nociceptor neurons direct goblet cells via a CGRP-RAMP1 axis to drive mucus production and gut barrier protection. Yang D, ...
Spatial organization of bacterial flora in normal and inflamed intestine: a fluorescence in situ hybridization study in mice
Beginning in the middle colon, a mucus gap of growing thickness physically separated all intestinal bacteria from contact with ... increased thickness and spread of the mucus gap, and massive increases of bacterial concentrations in the crypt and interlaced ...
Expression of pendrin and periostin in allergic rhinitis and chronic rhinosinusitis
These findings suggest that pendrin can induce mucus production and that periostin can induce tissue fibrosis and remodeling in ... These findings suggest that pendrin can induce mucus production and that periostin can induce tissue fibrosis and remodeling in ...
Polynesian bronchiectasis
Six Polynesian children aged 8-14 years with recurrent lower respiratory infections and abnormal lung mucociliary clearance were assessed for immuno-deficiency. Measurements were made in these 6 children and in 21 healthy Polynesians of serum immunoglobulins (IgG, IgM, IgA) and complement components …
Mucin expression in peripheral airways of patients with chronic obstructive pulmonary disease
Histochemical staining and immunoreactivity of bronchiolar epithelium were graded and the presence or absence of stained mucus ...
Park A[au] - Search Results - PubMed
Mucus sialylation determines intestinal host-commensal homeostasis. Yao Y, Kim G, Shafer S, Chen Z, Kubo S, Ji Y, Luo J, Yang W ...
Bacterial overgrowth and inflammation of small intestine after carboxymethylcellulose ingestion in genetically susceptible mice
Background: Detergents and emulsifiers added to food may destroy the mucus barrier, which normally isolates bacteria from the ...
Airway epithelial SPDEF integrates goblet cell differentiation and pulmonary Th2 inflammation
... where they regulate goblet cell differentiation and mucus production. Moreover, these transcription factors are upregulated in ...
Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation
To infer possible mechanisms of acute airway inflammation and mucus hypersecretion in acute severe asthma, we performed ... To infer possible mechanisms of acute airway inflammation and mucus hypersecretion in acute severe asthma, we performed ...