Direct thrombin inhibitors such as Lepirudin possess no heparin-like immunological properties and seem to have become the ... We report a pregnant woman with systemic lupus erythematosus and recurrent venous thromboembolism who suffered from heparin- ... to prevent any further platelet and coagulation activation during the clamping phase. Six months later the patient underwent ... Recombinant hirudin is a potent and specific thrombin inhibitor that can be used as a safe and effective anticoagulant in ...

In recent studies, r-hirudin as a potent and specific thrombin inhibitor, was demonstrated to be a safe and effective ... Other risk factors were massive bleeding, and positive lupus anticoagulant. However, the case of the ovarian cystectomy had ... This case had been controlled well with an antiplatelet agent and an anticoagulant while the levels of coagulation and ... Recombinant hirudin is a potent and specific thrombin inhibitor that can be used as a safe and effective anticoagulant in ...