Viruses | Free Full-Text | Griffithsin: An Antiviral Lectin with Outstanding Therapeutic Potential
... and in vitro and pre-clinical results that support the therapeutic potential of this lectin. ... an algae-derived lectin, is one of the most potent viral entry inhibitors discovered to date. It is currently being developed ... lectin (HHA), and galanthus nivalis lectin (GNA) in virus infectivity assays [29]. Synergy is more pronounced for some lectin ... Some lectins provide protection to the host from other organisms. Lectins have been developed widely as probes to investigate ...
Cells | Free Full-Text | Discovery, Function, and Therapeutic Targeting of Siglec-8
... sialic acid-binding immunoglobulin-like lectins) are single-pass cell surface receptors that have inhibitory activities on ... Varki, A.; Angata, T. Siglecs-the major subfamily of I-type lectins. Glycobiology 2006, 16, 1R-27R. [Google Scholar] [CrossRef ... Siglecs: A family of sialic-acid binding lectins. Glycobiology 1998, 8, 5-6. [Google Scholar] [CrossRef][Green Version] ... Siglecs (sialic acid-binding immunoglobulin-like lectins) are single-pass cell surface receptors that contain sialic acid- ...
Vaccines | Free Full-Text | Dendritic Cell Tumor Vaccination via Fc Gamma Receptor Targeting: Lessons Learned from Pre-Clinical...
Van Vliet, S.J.; Garcia-Vallejo, J.J.; van Kooyk, Y. Dendritic cells and C-type lectin receptors: Coupling innate to adaptive ... membrane-associated C-type lectin receptors (CLRs) [23], and mannose receptors [24,25,26,27,28,29]. Following the recognition ...
JCM | Free Full-Text | Sequential Circulating Tumor Cell Counts in Patients with Locally Advanced or Metastatic Hepatocellular...
Novel HCC biomarkers such as des-gamma-carboxyprothrombin and lectin-bound AFP have been considered for overcoming the drawback ... Alpha-fetoprotein, des-gamma carboxyprothrombin, and lectin-bound alpha-fetoprotein in early hepatocellular carcinoma. ...
Nutrients | Free Full-Text | Possible Prevention of Diabetes with a Gluten-Free Diet
... do evolutionary novel dietary lectins cause leptin resistance? BMC Endocr. Disord. 2005, 5, 10. [Google Scholar] [CrossRef] [ ...
Minerals | Free Full-Text | Exceptional Preservation of Fungi as H2-Bearing Fluid Inclusions in an Early Quaternary Paleo...
Fife, D.J.; Bruhn, D.F.; Miller, K.S.; Stoner, D.L. Evaluation of a fluorescent lectin-based staining technique for some ... Thin sections were stained with WGA-FITC (Sigma-Aldrich lectin from Triticum vulgaris FITC conjugate) according to the method ... The concentration of the lectin in the incubation medium was 50 μg/mL in 10 mmol/L phosphate buffer. After incubation the ...
IJMS | Free Full-Text | Advances in Proteomic Techniques for Cytokine Analysis: Focus on Melanoma Research
... lectins etc.) are prepared by ambient ion landing on MALDI plate. Samples are then added on the MALDI protein chip, covered ...
Vaccines | Free Full-Text | Manufacture of a Stable Lyophilized Formulation of the Live Attenuated Pertussis Vaccine BPZE1
Heparin-inhibitable lectin activity of the filamentous hemagglutinin adhesin of Bordetella pertussis. Infect. Immun. 1994, 62, ...
Vaccines | Free Full-Text | Role of the DNA-Binding Protein pA104R in ASFV Genome Packaging and as a Novel Target for Vaccine...
CD2v/EP402R and C-type lectin/EP153R) that represent another source of genetic diversity among ASFV isolates [5,26,28]. These ...
IJMS | Free Full-Text | Bioreactor Technologies for Enhanced Organoid Culture
Top) Whole organoid imaging using FITC-conjugated Griffonia simplicifolia lectin (green) to label the vasculature, overlaid ... Top) Whole organoid imaging using FITC-conjugated Griffonia simplicifolia lectin (green) to label the vasculature, overlaid ...
Toxins | Special Issue : Cholera Toxin
The fusogenic lectin-like property of CT has been explored for membrane transport, cell signalling, host cell biology and ...
Cells | Free Full-Text | Serum of Post-COVID-19 Syndrome Patients with or without ME/CFS Differentially Affects Endothelial...
Sankaralingam, S.; Xu, Y.; Sawamura, T.; Davidge, S.T. Increased Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 ...
Viruses | Free Full-Text | Dendritic Cells in Oncolytic Virus-Based Anti-Cancer Therapy
... they employ receptor-mediated endocytosis via C-type lectin receptors [43] or Fc (Fragment, crystallisable region of antibodies ...
Viruses | Free Full-Text | Plasmacytoid Dendritic Cells and the Control of Herpesvirus Infections
In humans, pDCs are characterized by selective high level expression of the C-type lectin CLEC4C (also referred to as BDCA2), ... Instead, mouse pDCs selectively express high levels of the C-type lectin SIGLECH, of the bone marrow stromal cell antigen 2 ( ... which is triggered on human pDCs by engagement of FcεRIγ-associated membrane receptors of the C-type lectin (CLEC4C/BDCA2) or ... the mouse SIGLECH C-type lectin receptor which associates with the ITAM-bearing adaptor DAP12 has also been shown to inhibit ...
IJMS | Free Full-Text | Extracellular Vesicle-Mediated Cell-Cell Communication in the Nervous System: Focus on Neurological...
Acts as an Oligomannose-Binding Lectin, and Promotes Neurite Outgrowth and Neuronal Survival When Released via Glia-Derived ...
Biomolecules | Topical Collection : Feature Papers in Enzymology
... with a ricin-type β-trefoil lectin domain (RICIN)-like domain from Cellulosimicrobium funkei HY-13 was identified [...] Read ... with a ricin-type β-trefoil lectin domain (RICIN)-like domain from Cellulosimicrobium funkei HY-13 was identified and ...
IJMS | Free Full-Text | Dendritic Cell and T Cell Crosstalk in Liver Fibrogenesis and Hepatocarcinogenesis: Implications for...
DCs can bind selectively to Kupffer cells via lectin-like receptors, an interaction that seems to be essential for DC ...
Vaccines | Free Full-Text | Adjuvants in the Driver's Seat: How Magnitude, Type, Fine Specificity and Longevity of Immune...
The relatively recent focus on C-type lectins as targets of novel adjuvants has provided an unexpected insight into the ...
JPM | Free Full-Text | The Role of Soluble LAG3 and Soluble Immune Checkpoints Profile in Advanced Head and Neck Cancer: A...
... a member of the C-type lectin receptor superfamily, typically exposed on tumor cell membranes, and with the fibrinogen like ...
IJMS | October-1 2022 - Browse Articles
The Tn antigen can be recognized by the Macrophage Galactose/GalNAc lectin (MGL), which mediates various immune regulatory and ...
Molecules | Free Full-Text | The [DPPH●/DPPH-H]-HPLC-DAD Method on Tracking the Antioxidant Activity of Pure Antioxidants and...
... lectins, and glycoproteins-binding carbohydrates [44,45]. However, the content of bioactive compounds in the raw material ...
Toxins | August 2018 - Browse Articles
In contrast, the expression of some genes related to glutathione S-transferase 1, C-type lectin, complement C1q tumor necrosis ...
Marine Drugs | Free Full-Text | Seaweeds as a Functional Ingredient for a Healthy Diet
Chlorophyta), reduces the density of non-metastatic prostate tumor cells [62]. The most abundant amino acids are lectins, ... The lectins found in Bryothamnion spp. (Rhodophyta) show an inhibitory effect on the growth of strains of Steptococcus spp.; ... Effect of algae and plant lectins on planktonic growth and biofilm formation in clinically relevant bacteria and yeasts. Biomed ...
IJPB | Free Full-Text | Exploring the Role of Salicylic Acid in Regulating the Colonization Ability of Bacillus subtilis 26D in...
Maize Root Lectins Mediate the Interaction with Herbaspirillum seropedicae via N-acetyl Glucosamine Residues of ...
Biosensors | March 2017 - Browse Articles
... as well as their carbohydrate binding specificities was determined for the three lectins. One of these lectins, BLL2, was able ... High Bacterial Agglutination Activity in a Single-CRD C-Type Lectin from Spodoptera exigua (Lepidoptera: Noctuidae) by Leila ... Lectins are carbohydrate-interacting proteins that play a pivotal role in multiple physiological and developmental aspects of ... Lectins are carbohydrate-interacting proteins that play a pivotal role in multiple physiological and developmental aspects of ...
Marine Drugs | May 2019 - Browse Articles
This article belongs to the Special Issue Marine Glycobiology, Glycomics and Lectins). ...
Nutrients | July 2015 - Browse Articles
Lectin, urease, trypsin inhibitor, peroxidase and chitinase activities were higher in the resistant cultivar. Growing rats were ... Based on regression analysis, lectin, trypsin inhibitor, peroxidase and chitinase appear to be involved in the resistance trait ...
Marine Drugs | Free Full-Text | A Comparative Study of Oncolytic Vaccinia Viruses Harboring Different Marine Lectins in Breast...
Aphrocallistes vastus lectin (oncoVV-AVL), white-spotted charr lectin (oncoVV-WCL), and Asterina pectinifera lectin (oncoVV-APL ... Further studies showed that apoptosis and replication may work together to enhance the cytotoxicity of oncoVV-lectins in a cell ... This study aims to compare the efficacy of oncolytic vaccinia viruses harboring Tachypleus tridentatus lectin (oncoVV-TTL), ... Our previous studies demonstrated that arming vaccinia viruses with marine lectins enhanced the antitumor efficacy in several ...
JDB | Free Full-Text | The Complex Bridge between Aquatic and Terrestrial Life: Skin Changes during Development of Amphibians
Faszewski, E.E.; Kaltenbach, J.C. Histology and lectin-binding patterns in the skin of the terrestrial horned frog Ceratophrys ...
Marine Drugs | Special Issue : Nutra-Cosmeceuticals from Algae for Health and Wellness
... lectins, or peptides. Extraction of seaweed proteins requires the application of disruptive methods due to the heterogeneous ...