G protein-coupled receptors that influence lifespan of human and animal models | SpringerLink
Dixit A, Sandhu A, Modi S et al (2020) Neuronal control of lipid metabolism by STR-2 G protein-coupled receptor promotes ... The joint activation of the G protein-coupled bile acid receptor 1 (GPBAR1) and FXR in old mice can act as caloric restriction ... it undergoes a conformational change that allows it to interact with a heterotrimeric G protein (composed of alpha (α), beta (β ... Silencing isoform B of the metabotropic glutamate receptor (mGluR) in Drosophila reduced both median and maximum lifespan, ...