Insulin-like growth factor I (domestic guinea pig) | Protein Target - PubChem
Protein target information for Insulin-like growth factor I (domestic guinea pig). Find diseases associated with this ...
Premature birth and later insulin resistance
... children who were born prematurely have an isolated reduction in insulin sensitivity, which may be a risk factor for type 2 ... Insulin sensitivity was measured with the use of paired insulin and glucose data obtained by frequent measurements during ... Premature birth and later insulin resistance N Engl J Med. 2004 Nov 18;351(21):2179-86. doi: 10.1056/NEJMoa042275. ... We hypothesized that insulin resistance, a marker of type 2 diabetes mellitus, would be prevalent among children who had been ...
Multiplexed biomarkers of insulin resistance - Patent US-2011311650-A1 - PubChem
US-2011311650-A1 chemical patent summary.
Insulin-like growth factor 1 receptor-specific antibodies and uses thereof - Patent US-10100117-B2 - PubChem
US-10100117-B2 chemical patent summary.
Clinical review 97: Syndromes of severe insulin resistance
... J Clin Endocrinol Metab. 1998 Sep;83(9):3025-30. doi: 10.1210/jcem. ...
![Igf2r insulin-like growth factor 2 receptor [Mus musculus (house mouse)] - Gene - NCBI](data:image/png;base64,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)
Igf2r insulin-like growth factor 2 receptor [Mus musculus (house mouse)] - Gene - NCBI
Igf2r insulin-like growth factor 2 receptor [Mus musculus] Igf2r insulin-like growth factor 2 receptor [Mus musculus]. Gene ID: ... insulin-like growth factor 2 receptorprovided by MGI. Primary source. MGI:MGI:96435 See related. Ensembl:ENSMUSG00000023830 ... Igf2r insulin-like growth factor 2 receptor [ Mus musculus (house mouse) ] Gene ID: 16004, updated on 23-Nov-2023 ... enables insulin-like growth factor binding IBA Inferred from Biological aspect of Ancestor. more info ...
Insulin patents and market exclusivities: unresolved issues--Authors' reply
Insulin patents and market exclusivities: unresolved issues--Authors reply Lancet Diabetes Endocrinol. 2016 Feb;4(2):98-9. doi ...
Effects of antipsychotic medications on appetite, weight, and insulin resistance
... Endocrinol Metab Clin North Am. 2013 Sep;42(3 ... This review focuses on the effects of APDs on weight gain, appetite, insulin resistance, and glucose dysregulation, and the ...
1HIT: Receptor binding redefined by a structural switch in a mutant Human Insulin
... ...
Hypermagnesiuria in children with newly diagnosed insulin-dependent diabetes mellitus
The renal handling of magnesium was, therefore, studied in 37 children with newly diagnosed insulin-dependent dia … ... In newly diagnosed insulin-dependent diabetes mellitus, the mechanisms underlying the concomitant occurrence of magnesium ... Hypermagnesiuria in children with newly diagnosed insulin-dependent diabetes mellitus Am J Nephrol. 1994;14(3):201-6. doi: ... In newly diagnosed insulin-dependent diabetes mellitus, the mechanisms underlying the concomitant occurrence of magnesium ...
2HIU: NMR STRUCTURE OF HUMAN INSULIN IN 20% ACETIC ACID, ZINC-FREE, 10 STRUCTURES
... ...
Preservation of insulin effects on glucose production and proteolysis during fasting
To determine whether fasting alters the ability of insulin to suppress endogenous glucose production or proteolysis, isotopic ... Preservation of insulin effects on glucose production and proteolysis during fasting Am J Physiol. 1988 Jun;254(6 Pt 1):E700-7. ... Using the "pancreatic clamp" technique, we achieved small increments in plasma insulin concentrations, as well as constant and ... To determine whether fasting alters the ability of insulin to suppress endogenous glucose production or proteolysis, isotopic ...
mTOR is a key modulator of ageing and age-related disease
Insulin-Like Growth Factor I / metabolism * Longevity / genetics * Signal Transduction * TOR Serine-Threonine Kinases / ...
Regional impact of adipose tissue morphology on the metabolic profile in morbid obesity
... adipocyte size was significantly associated with plasma insulin and glucose, insulin-induced glucose disposal and insulin ... Hyperplasia (many small adipocytes) in both adipose regions may be protective against lipid as well as glucose/insulin ... insulin and lipid profiles compared with adipose hypertrophy (i.e. few large adipocytes) in any or both regions (p ranging from ... whereas large subcutaneous adipocytes are important for glucose and insulin abnormalities. ...
Protein therapeutics: a summary and pharmacological classification
... human insulin--25 years ago. Protein therapeutics already have a significant role in almost every fiel … ... human insulin--25 years ago. Protein therapeutics already have a significant role in almost every field of medicine, but this ...
Management of canine diabetes
Insulin is the mainstay of therapy for diabetic dogs, and a conservative approach to insulin therapy is crucial. Most diabetic ... dogs require twice-daily dosing with lente or NPH insulin to adequately control their clinical signs. The diet fed should ...
What is the value of faster acting prandial insulin? Focus on ultra rapid lispro
... control compared with regular human insulin. However, their absorption rate and time action following subcutaneous ... Rapid-acting insulins (RAIs) have been instrumental in the management of diabetes because of their improved postprandial ... What is the value of faster acting prandial insulin? Focus on ultra rapid lispro Diabetes Obes Metab. 2022 Sep;24(9):1689-1701. ... Rapid-acting insulins (RAIs) have been instrumental in the management of diabetes because of their improved postprandial ...
Estrogen and insulin transport through the blood-brain barrier
... by dietary intervention improves the transport of insulin through the BBB and the sensitivity of insulin in the brain. Although ... Obesity is associated with insulin resistance and reduced transport of insulin through the blood-brain barrier (BBB). Reversal ... Thus, the reduction of brain insulin sensitivity by E2 is unlikely to be mediated by increasing the amount of insulin entering ... Obesity is associated with insulin resistance and reduced transport of insulin through the blood-brain barrier (BBB). Reversal ...
Insulin secretion and sensitivity in space flight: diabetogenic effects
Alterations in insulin secretion, insulin sensitivity, glucose tolerance, and metabolism of protein and amino acids support the ... Alterations in insulin secretion, insulin sensitivity, glucose tolerance, and metabolism of protein and amino acids support the ... We propose that measures of insulin secretion and insulin action will be necessary to design effective countermeasures against ... Insulin secretion and sensitivity in space flight: diabetogenic effects Nutrition. 2002 Oct;18(10):842-8. doi: 10.1016/s0899- ...
Anti-diabetic effects of cinnamaldehyde and berberine and their impacts on retinol-binding protein 4 expression in rats with...
Results: After treatment for four weeks, both Cin and Ber displayed significant hypolipidemic, hypoglycemic, and insulin ... in insulin resistance (IR) state and to have an intimate relationship with IR and type 2 diabetes mellitus (T2DM). The present ... and homeostasis model assessment of insulin resistance (HOMA-IR) seem even better than that of Met. Cin and Ber markedly ...
Carnitine revisited: potential use as adjunctive treatment in diabetes
... lipid overload and glucose intolerance in obese rodents by enhancing mitochondrial efflux of excess acyl groups from insulin- ... Materials and methods: Obese mice with genetic or diet-induced forms of insulin resistance were fed rodent chow +/- 0.5% L: - ... Metabolic outcomes included insulin tolerance tests, indirect calorimetry and mass spectrometry-based profiling of acyl- ... Similarly, under insulin-stimulated conditions, carbohydrate oxidation was higher and total energy expenditure increased from ...
3LRI: Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I
... ...
Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States
After adding leptin and insulin concentrations, abnormal ALT activity was most strongly associated with higher WHR (odds ratio ... insulin, and glucose concentrations. The proportion of elevated ALT activity due to overweight and obesity (BMI , or =25 kg/m(2 ... OR], 1.32; 95% confidence interval [CI], 1.12-1.56) and leptin (OR, 1.12; 95% CI, 1.01-1.24) and insulin (OR, 1.27; 95% CI, ...
L-citrulline-malate influence over branched chain amino acid utilization during exercise
Insulin levels significantly increased after exercise in both groups (p , 0.05) returning to basal values at recovery. Growth ...
The role of melatonin in diabetes: therapeutic implications
The effects of melatonin on insulin secretion are mediated through the melatonin receptors (MT1 and MT2). It decreases insulin ... The effects of melatonin on insulin secretion are mediated through the melatonin receptors (MT1 and MT2). It decreases insulin ... Evidences from experimental studies proved that melatonin induces production of insulin growth factor and promotes insulin ... consequently increases insulin secretion. Both in vivo and in vitro, insulin secretion by the pancreatic islets in a circadian ...
Systematic prevention of bubble formation and accumulation for long-term culture of pancreatic islet cells in microfluidic...
In addition to demonstrating normal cell viability and islet morphology, post-cultured islets exhibited normal insulin ...
Protein metabolism in obesity: effects of body fat distribution and hyperinsulinemia on leucine turnover
... and again during an infusion of low physiologic amounts of insulin (insulin clamp). Results showed that basal leucine carbon ... We conclude that moderate obesity is associated with increased proteolysis and that insulins antiproteolytic actions are ... Leucine carbon flux was not suppressed during the insulin-clamp study in UB Ob women but was in the LB Ob and Non Ob women. ...
Partial pancreatic transdifferentiation of primary human hepatocytes in the livers of a humanised mouse model
We have previously shown that the introduction of furin-cleavable human insulin (INS-FUR) to the livers in several animal ... IPGTTs of the insulin-transduced animals were not significantly different from nondiabetic animals. Immunofluorescence ... microscopy revealed the expression of human albumin and insulin in transduced liver samples. Quantitative RT-PCR showed ...
Costs of managing severe hypoglycaemia in three European countries
Average costs were lower for type 1 than for insulin-treated type 2 diabetes, in all three countries. ... Methods: Healthcare resource use was measured by surveying 639 patients aged ≥ 16 years, receiving insulin for type 1 (n=319) ... Average costs were lower for type 1 than for insulin-treated type 2 diabetes, in all three countries. ...
The Effects of Oral Magnesium Supplementation on Glycemic Response among Type 2 Diabetes Patients
Conclusion: The results of this study revealed that oral Mg supplementation reduces insulin resistance and improves the ... insulin levels (IL) (15.56 to 12.18 μIU/mL, p , 0.001), C-peptide (2.28 to 1.90 ng/mL, p = 0.001), HOMA.IR (6.16 to 4.44, p , ...