Our classifier failed to detect any ibuprofen induced pharmacodynamic effects on the brain. Ibuprofen is not a centrally acting ... Ibuprofen showed no such evidence, with discrimination below chance (p=0.92). At a study level, the gabapentin arm showed ... We expected our protocol to detect gabapentin to show evidence of effective analgesia but not ibuprofen. Methods: We separately ... Results: Gabapentin, but not ibuprofen, showed evidence of a reliable pharmacodynamic effect. Using a classifier based on the ...
The NNT for at least 50% pain relief is similar to that of commonly used NSAIDs such as ibuprofen and naproxen at usual doses. ... related to ibuprofen and naproxen, used to treat acute and chronic painful conditions. There is no systematic review of its use ... The NNT for at least 50% pain relief is similar to that of commonly used NSAIDs such as ibuprofen and naproxen at usual doses. ... BACKGROUND: Flurbiprofen is a non-selective non-steroidal anti-inflammatory drug (NSAID), related to ibuprofen and naproxen, ...