Loading...
*  Evolution of Biological Hydrogen Production - Buz Barstow
Iron-iron hydrogenases are highly active hydrogen-producing enzymes. Hydrogenases mediate molecular processes of broad ... Evolution of Biological Hydrogen Production. Barstow, Buz Michael / Harvard University. $53,942. NIH 2011. F32 GM. Evolution of ... Evolution of Biological Hydrogen Production Barstow, Buz Michael Harvard University, Boston, MA, United States ... Finally, the coupling of hydrogenases to photosynthesis offers the possibility of the clean production of hydrogen by ...
http://grantome.com/grant/NIH/F32-GM089028-03
*  Regulation of Nox Enzymes by Calcium and Novel Subunits - John Lambeth
2011) The E-loop is involved in hydrogen peroxide formation by the NADPH oxidase Nox4. J Biol Chem 286:13304-13 ... 2014) Nox4: a hydrogen peroxide-generating oxygen sensor. Biochemistry 53:5111-20 ...
http://grantome.com/grant/NIH/R01-CA105116-09
*  Structure and Function of Circadian Clock Light Sensors - Brian Crane
2016) Changes in active site histidine hydrogen bonding trigger cryptochrome activation. Proc Natl Acad Sci U S A 113:10073-8 ...
http://grantome.com/grant/NIH/R01-GM079679-06
*  Roles of Glycoconjugates and Redox Signaling in Tumor Biology - David Roberts
Hydrogen sulfide (H2S) is an endogenous signaling molecule that may act via protein sulfhydrylation to regulate various ... 2012) Hydrogen sulfide is an endogenous potentiator of T cell activation. J Biol Chem 287:4211-21 ... Hydrogen sulfide (H2S) is an endogenous signaling molecule that may act via protein sulfhydrylation to regulate various ...
http://grantome.com/grant/NIH/ZIA-SC009174-24
*  Chemistry of Biological Systems - Hening Lin
2016) Changes in active site histidine hydrogen bonding trigger cryptochrome activation. Proc Natl Acad Sci U S A 113:10073-8 ...
http://grantome.com/grant/NIH/T32-GM008500-19
*  Control of AMPA receptor function by phosphorylation - Stephen Traynelis
We will identify intracellular GluR1 residues as phospho-Ser831 hydrogen bonding partners. We will additionally search for ...
http://grantome.com/grant/NIH/R01-NS068464-04
*  Biomolecular Recognition with Artificial Alpha Helices - Paramjit Arora
Joy, Stephen T; Arora, Paramjit S (2016) An optimal hydrogen-bond surrogate for α-helices. Chem Commun (Camb) 52:5738-41 ... Miller, Stephen E; Thomson, Paul F; Arora, Paramjit S (2014) Synthesis of hydrogen-bond surrogate α-helices as inhibitors of ... Our strategy involves replacement of one of the main chain hydrogen bonds in the target alpha-helix with a covalent bond. The ...
http://grantome.com/grant/NIH/R01-GM073943-08
*  Metal Binding to the Bacterial Cell Wall - Charles Rice
2015) Sterilization of hydrogen peroxide resistant bacterial spores with stabilized chlorine dioxide. AMB Express 5:24 ...
http://grantome.com/grant/NIH/R01-GM090064-05
*  eNOS-actin Interaction and Oxygen in Lung Endothelium - Yunchao Su
2011) Hydrogen sulfide ameliorates tobacco smoke-induced oxidative stress and emphysema in mice. Antioxid Redox Signal 15:2121- ...
http://grantome.com/grant/NIH/R01-HL088261-05
*  Global Cysteine Modifications in Human Pathogens - Chuan He
2014) Steady-state hydrogen peroxide induces glycolysis in Staphylococcus aureus and Pseudomonas aeruginosa. J Bacteriol 196: ...
http://grantome.com/grant/NIH/R01-AI074658-08
*  The Basic and Translational Implication of SIRT1 and DNMT1 in Cancer - Edward Seto
2014) Deacetylation of the tumor suppressor protein PML regulates hydrogen peroxide-induced cell death. Cell Death Dis 5:e1340 ...
http://grantome.com/grant/NIH/R01-CA169210-01
*  Copper-Induced Amyloidosis Studied by Mass Spectrometry - Richard Vachet
Zhang, Zhe; Vachet, Richard W (2015) Kinetics of Protein Complex Dissociation Studied by Hydrogen/Deuterium Exchange and Mass ... 2014) Identifying Zn-bound histidine residues in metalloproteins using hydrogen-deuterium exchange mass spectrometry. Anal Chem ...
http://grantome.com/grant/NIH/R01-GM075092-06
*  Electrostatics and Dynamics in Proteins - Steven Boxer
Oltrogge, Luke M; Boxer, Steven G (2015) Short Hydrogen Bonds and Proton Delocalization in Green Fluorescent Protein (GFP). ACS ... Wu, Yufan; Fried, Stephen D; Boxer, Steven G (2015) Dissecting Proton Delocalization in an Enzyme's Hydrogen Bond Network with ... Levinson, Nicholas M; Boxer, Steven G (2014) A conserved water-mediated hydrogen bond network defines bosutinib's kinase ...
http://grantome.com/grant/NIH/R01-GM027738-32
*  Cancer Biology Training Program - Tarun Kapoor
2013) The yeast Snt2 protein coordinates the transcriptional response to hydrogen peroxide-mediated oxidative stress. Mol Cell ...
http://grantome.com/grant/NIH/T32-CA009673-36A1
*  Ionic currents in gastrointestinal smooth muscle - Hamid Akbarali
2015) Interaction between hydrogen sulfide-induced sulfhydration and tyrosine nitration in the KATP channel complex. Am J ...
http://grantome.com/grant/NIH/R01-DK046367-18A1
*  Therapeutic Angiogenesis in Vascular Medicine IV - Raj Kishore
2016) Restoration of Hydrogen Sulfide Production in Diabetic Mice Improves Reparative Function of Bone Marrow Cells. ...
http://grantome.com/grant/NIH/R01-HL053354-14
*  HIV-1 reverse transcriptase structure: function, inhibition, and resistance - Edward Arnold
2015) Differential isotopic enrichment to facilitate characterization of asymmetric multimeric proteins using hydrogen/ ...
http://grantome.com/grant/NIH/R37-AI027690-24
*  Inhibition of Protein-Protein Contacts in VEGF Transcription by Synthetic Helices - Paramjit Arora
2010) Inhibition of hypoxia inducible factor 1-transcription coactivator interaction by a hydrogen bond surrogate alpha-helix. ... 2012) Correction to Inhibition of Hypoxia Inducible Factor 1-Transcription Coactivator Interaction by a Hydrogen Bond Surrogate ...
http://grantome.com/grant/NIH/R21-HL094969-02
*  Molecular Species Responsible for Tumor Supressive Effect of MnSOD - Frederick Domann
Glucose oxidase produces hydrogen peroxide when glucose is present as substrate and thus this experiment will examine further ... For example, we already have data showing hydrogen peroxide is involved in the growth suppressive effect of MnSOD over- ... We propose that there are only three logical possibilities: superoxide radical, hydrogen peroxide, or nitric oxide radical. We ... expression and so we plan to study the antitumor effect of MnSOD over-expression combined with inhibitors of hydrogen peroxide ...
http://grantome.com/grant/NIH/R01-CA115438-04
*  Protein Cleavage Sites in Experimental Cataractous Lens - Larry David
2015) Determination of Histidine pKa Values in the Propeptides of Furin and Proprotein Convertase 1/3 Using Histidine Hydrogen- ... 2016) Differences in solution dynamics between lens β-crystallin homodimers and heterodimers probed by hydrogen-deuterium ...
http://grantome.com/grant/NIH/R01-EY007755-21
*  Regulation Microvascular Smooth Muscle Ca2+ &BK+ ECM-Integrin-Cytoskeletal Axis - Michael Davis
Intravital microscopic methods to evaluate anti-inflammatory effects and signaling mechanisms evoked by hydrogen sulfide. ...
http://grantome.com/grant/NIH/P01-HL095486-03-7912
*  Mitochondria-targeted Agents in Breast Cancer - Balaraman Kalyanaraman
2016) Recent developments in detection of superoxide radical anion and hydrogen peroxide: Opportunities, challenges, and ...
http://grantome.com/grant/NIH/R01-CA152810-04
*  Signals from the reproductive system that regulate aging in C. elegans - Cynthia Kenyon
Wei, Yuehua; Kenyon, Cynthia (2016) Roles for ROS and hydrogen sulfide in the longevity response to germline loss in ...
http://grantome.com/grant/NIH/R01-AG032435-06
*  Role of Reactive Oxygen Species in B Lymphoma Fate - Gregory Carey
... and reduces hydrogen peroxide to induce lymphoma apoptosis. Exp Cell Res 332:136-45 ...
http://grantome.com/grant/NIH/UH2-CA158689-02
*  Transmitters in Altered Carotid Body Function - Nanduri Prabhakar
Prabhakar, Nanduri R (2012) Carbon monoxide (CO) and hydrogen sulfide (H(2)S) in hypoxic sensing by the carotid body. Respir ...
http://grantome.com/grant/NIH/R01-HL086493-05