... from the G protein-geranyl-geranyl interaction face of the Ig-like domain of the Rho guanine nucleotide dissociation inhibitor ... Sjolinder, M., Uhlmann, J. and Ponsting, H. (2002). DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, ... In order to identify the function of deafness locus putative guanine nucleotide exchange factor (DelGEF), a protein homologous ... On epidermal growth factor (EGF) stimulation, activated Ras recruits guanine nucleotide exchange factors (GEFs) for RalA, ...

This study found that Parcas (Pcs), recently shown to have guanine-nucleotide-exchange (GEF) activity toward Rab11, co- ... It is possible that unrelenting phosphorylation of Rip11 by PKA may cause the premature dissociation of Rab11 and its effectors ... this study tested whether inhibitors of this pathway might antagonize the effects of EF. In human endothelial cells, it was ... This role in spatial organization of the cell requires specific guanine nucleotide exchange factors (GEFs) to activate each Rab ...

The guanine nucleotide exchange factor (GEF) ephexin1 (Drosophila homolog: CG3799) interacts with EphA4 and has been suggested ... This dissociation can be reversed by co-injection of RNA encoding C-cadherin, suggesting that one or more cadherins could be ... Pretreatment of ganglion cell axons with C3-transferase, a specific inhibitor of the Rho GTPase, or with Y-27632, a specific ... Ephexin is a novel Eph receptor-interacting protein that is a member of the Dbl family of guanine nucleotide exchange factors ( ...