In addition, if the patient has received antibiotics during the preceding 3 months, a different class of antibiotics should be ... Other effective antimicrobials are available only in parenteral form (eg, cefoxitin, cefotetan). If aerobic gram-negative ... a combination of metronidazole plus a macrolide or a second- or third-generation cephalosporin, and the newer quinolones (eg, ... 62, 63, 64] In patients without nasal polyps, 3 months of a macrolide antibiotic may be useful. [65] ...

Quinolones have broad activity against gram-positive and gram-negative aerobic organisms but no activity against anaerobes. ... Macrolides. The best initial antibiotic choice is thought to be a macrolide. Macrolides provide the best coverage for the most ... Macrolides, as a class, have the potential disadvantage of causing gastrointestinal (GI) upset. Compared with erythromycin, ... Meropenem is effective against most gram-positive and gram-negative bacteria and has slightly increased activity against gram- ...

Anaerobic gram-positive cocci include various clinically significant species of the genus Peptostreptococcus. ... Effective against most gram-positive and gram-negative bacteria. Has slightly increased activity against gram-negatives and ... Macrolides are active against pigmented Prevotella and Porphyromonas species and microaerophilic streptococci, gram-positive ... A glycylcycline antibiotic that is structurally similar to tetracycline antibiotics. Inhibits bacterial protein translation by ...

Recent research has focused on cost-effective antibiotic therapy and concern for emergence of antibiotic resistance among both ... Patients with negative Gram stain results and a history consistent with urethritis who are not likely to return for follow-up ... 4, 24, 25, 27] Couldwell et al described rates of resistance of 15% for quinolones and 43% for macrolides in 143 M genitalium ... Regardless of symptoms, administer antibiotics to the following individuals:. * Patients with positive Gram stain or culture ...