The first general method is rational drug design based on mimicking the transition state of the chemical reaction catalysed by ... This results from the active site containing two different binding sites within the active site, one for each substrate. For ... than substrate-based designs. An example of such a transition state inhibitor is the antiviral drug oseltamivir; this drug ... Lindquist RN (October 2013). "The design of enzyme inhibitors: Transition state analogues.". In Ariëns EJ (ed.). Drug Design: ...

... "a set of methods designed to describe and interpret observed and inferred phenomena, past or present, and aimed at building a ... "Anti-vaccination websites use science and stories to support claims, study finds". Johns Hopkins. Science Daily. Archived ... Beyerstein B, Hadaway P (1991). "On avoiding folly". Journal of Drug Issues. 20 (4): 689-700. doi:10.1177/002204269002000418. ... Examples of this ideological process are creation science and intelligent design, which were developed in response to the ...

Webpages. *Kassim, Sadik H. "The Role of Religion in the Generation of Suicide Bombers" Archived 2013-06-06 at the Wayback ... Furthermore, hijacking methods of transportation or crucifying people in order to spread fear are also crimes of hiraba. ... Also excluded from the definition are "proxy bombings", which may have political goals and may be designed to look like suicide ... For years, the conventional wisdom has been that suicide terrorists are rational political actors, while suicidal rampage ...