Fucose is an important determinant". Journal of Biological Chemistry. 256 (13): 6633-6640. doi:10.1016/s0021-9258(19)69037-x. ... Fucose is an important determinant". Journal of Biological Chemistry. 256 (13): 6633-6640. doi:10.1016/S0021-9258(19)69037-X. ...
Yuen R, Schachter H (1972). "L-Fucose metabolism in mammals. I. Port liver L-fuconate hydro-lyase". Can. J. Biochem. 50 (7): ...
1992, ; Neo-Latin noun fucosum, fucose; Neo-Latin masculine gender adjective fucosus (sic), containing fucose in the cell wall ...
The paucimannosidic glycans may also be modified with other types of monosaccharides including fucose (Fuc) and xylose (Xyl) ... 3-linked fucose". FEBS Letters. 561 (1-3): 132-136. doi:10.1016/s0014-5793(04)00150-4. ISSN 0014-5793. PMID 15013764. S2CID ... 3-linked fucose and xylose substitutions". Glycobiology. 11 (4): 261-274. doi:10.1093/glycob/11.4.261. ISSN 0959-6658. PMID ... "Galactosylated Fucose Epitopes in Nematodes". Journal of Biological Chemistry. 287 (34): 28276-28290. doi:10.1074/jbc. ...
Addition of a fucose alone creates the H-antigen, present in people with blood type O. By adding a galactose onto this ... Addition of fucose sugars to serine and threonine residues is an unusual form of O-glycosylation that occurs in the endoplasmic ... Once the core O-fucose has been added, it is often elongated by addition of GlcNAc, galactose and sialic acid. Notch is an ... Addition of fucose sugars by fucosyltransferases forms Lewis epitopes and the scaffold for blood group determinants. ...
Dahms AS, Anderson RL (1972). "D-Fucose metabolism in a pseudomonad. 3. Conversion of D-fuconate to 2-keto-3-deoxy-D-fuconate ...
Fucose supplementation has had a partial effect on some SLC35C1-CDG patients. The first CDG patients (twin sisters) were ... caused by a GDP-fucose (Fuc) transporter deficiency. All N-linked oligosaccharides originate from a common lipid-linked ... a generalized defect in fucose metabolism". The Journal of Pediatrics. 134 (6): 681-688. doi:10.1016/S0022-3476(99)70281-7. PMC ...
It is the enzyme GDP-L-fucose synthase. This theory in part could also explain why some patients report amelioration under ... "GDP-l-fucose synthase is a CD4+ T cell-specific autoantigen in DRB3*02:02 patients with multiple sclerosis" (PDF). Science ...
In Arabidopsis, terminal sugars such as fucose are proposed to be added by AtFUT4 (a fucosyl transferase) and AtFUT6 in the ... Two α-fucosyltransferase genes, FUT4 and FUT6, both belonging to GT37 family, encode enzymes which add α-1,2-fucose residues to ... L-fucose (Fuc), D-glucopyranose (Glcp), D-glucuronic acid (GlcA) and its 4-O-methyl derivative, and D-galacturonic acid (GalA) ... fucose (Fuc), and glucuronic acid (GlcA). These AG glycan moieties are assembled by glycosyltransferases (GTs). O-glycosylation ...
Fucoidan is a polymer composed of sulfated L-fucose. Carrageenans are isolated from algae. Hyaluronan functions as a heparinoid ...
Chemically, it is a methyl ether of D-fucose. Sarmentose, a related deoxy sugar Digitalose, Merck Index, 12th Edition, 3202 ...
Alpha-Fucosidase is an enzyme that breaks down fucose. Fucosidosis is an autosomal recessive lysosomal storage disease caused ... by defective alpha-L-fucosidase with accumulation of fucose in the tissues. Different phenotypes include clinical features such ...
O-fucose modifications have only been detected in hEGF-like domains and they are important for the proper folding of the hEGF- ... Factor VII exhibits an O-linked fucose at Ser60. Multiple cbEGF domains are often connected by one or two amino acids to form ... These post-translational modifications include O-glycosylations, mostly O-fucose modifications, and β-hydroxylation of ...
... similarly fucose presents the same for certain bacteria and helminths; and glucans are present on mycobacteria and fungi. In ...
Park D, Choi D, Lee J, Lim DS, Park C (July 2010). "Male-like sexual behavior of female mouse lacking fucose mutarotase". BMC ... Those mice who retained the gene fucose mutarotase (FucM) were attracted to male mice. In interviews to the press, researchers ...
Dang S, Sun L, Huang Y, Lu F, Liu Y, Gong H, Wang J, Yan N (October 2010). "Structure of a fucose transporter in an outward- ...
Carbohydrates in the cell include glucose, fucose, galactose, and mannose. R. glutinis is heat resistant, an uncommon feature ...
Park D, Choi D, Lee J, Lim DS, Park C (July 2010). "Male-like sexual behavior of female mouse lacking fucose mutarotase". BMC ... Researchers found that disabling the fucose mutarotase (FucM) gene in laboratory mice - which influences the levels of estrogen ...
Mannose is the major cell-wall carbohydrate; glucose, fucose, and rhamnose are the less prevalent neutral sugars; and xylose is ...
... a generalized defect in fucose metabolism". The Journal of Pediatrics. 134 (6): 681-8. doi:10.1016/S0022-3476(99)70281-7. PMC ...
... converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved ... GDP-L-fucose synthetase is an enzyme that in humans is encoded by the TSTA3 gene. Tissue specific transplantation antigen P35B ... PDBe-KB provides an overview of all the structure information available in the PDB for Human GDP-L-fucose synthase v t e ( ... 1996). "Synthesis of GDP-L-fucose by the human FX protein". J. Biol. Chem. 271 (44): 27274-9. doi:10.1074/jbc.271.44.27274. ...
Fucose-1-phosphate guanylyltransferase is an enzyme that in humans is encoded by the FPGT gene. L-fucose is a key sugar in ... This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L- ... fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. GRCh38: Ensembl release 89: ... There are two alternate pathways for the biosynthesis of GDP-fucose; the major pathway converts GDP-alpha-D-mannose to GDP-beta ...
... fucose and N-acetylglucosamine. Thus, LCs may react against pathogens such as HIV-1, Mycobacterium leprae and Candida albicans ...
Moreover, it has been reported that fucosylation is an important regulator of anti-tumor immunity and L-fucose can be used as a ... Fucosylation is the process of adding fucose sugar units to a molecule. It is a type of glycosylation.[citation needed] It is ...
The addition of O-fucose by POFUT1 is absolutely necessary for notch function, and, without the enzyme to add O-fucose, all ... If Fringe adds a GlcNAc to the O-fucose sugar then the subsequent addition of a galactose and sialic acid will occur. In the ... An O-glucose sugar may be added between the first and second conserved cysteines, and an O-fucose may be added between the ... The Notch1-Dll4 structure also illuminated a direct role for Notch O-linked fucose and glucose moieties in ligand recognition, ...
"Synthesis of trifluoromethyl analogue of L-fucose and 6-deoxy-D-altrose". Journal of the Chemical Society, Chemical ...
Requirement of core alpha1,6-linked fucose and a polypeptide chain for polysialylation". The Journal of Biological Chemistry. ...
In HLA DRB3 cases, autoimmune reactions against the enzyme GDP-L-fucose synthase has been reported The same report points that ... In HLA-DRB3*02:02 patients, autoimmune reactions against the enzyme GDP-L-fucose synthase has been reported The same report ... October 2018). "GDP-l-fucose synthase is a CD4+ T cell-specific autoantigen in DRB3*02:02 patients with multiple sclerosis". ... Another possible type is one with auto-antibodies against GDP-L-fucose synthase. ...
The systematic name of this enzyme class is dTDP-D-fucose:NADP+ oxidoreductase. This enzyme is also called dTDP-4-keto-6- ... the two substrates of this enzyme are dTDP-D-fucose and NADP+, whereas its 3 products are dTDP-4-dehydro-6-deoxy-D-glucose, ... "A novel NDP-6-deoxyhexosyl-4-ulose reductase in the pathway for the synthesis of thymidine diphosphate-D-fucose". J. Biol. Chem ... is an enzyme that catalyzes the chemical reaction dTDP-D-fucose + NADP+ ⇌ {\displaystyle \rightleftharpoons } dTDP-4-dehydro-6- ...
The main components of the cell wall are fucose or galactose-derived substances. The reproduction of Labyrinthula occurs by ...