A Conserved GEF for Rho-Family GTPases Acts in an EGF Signaling Pathway to Promote Sleep-like Quiescence in Caenorhabditis...
2005 Vav family GEFs link activated Ephs to endocytosis and axon guidance. Neuron 46: 205-217. ... 2010 VAV2 regulates epidermal growth factor receptor endocytosis and degradation. Oncogene 29: 2528-2539. ... signaling by regulating the endocytosis of the RTKs (Cowan et al. 2005; Thalappilly et al. 2010). Indeed, Vav2, in a GEF- ... Whether VAV-1 has a role in mediating endocytosis and degradation of the LET-23/EGFR in the ALA interneuron will require ...
A Genomewide Suppressor and Enhancer Analysis of cdc13-1 Reveals Varied Cellular Processes Influencing Telomere Capping in...
... which include disruption of endocytosis (Breton et al. 2001; Lombardi and Riezman 2001). MAE1 encodes a mitochondrial malic ... and endocytosis. Since other genes involved in both vesicular traffic and Ash1 function have been identified in this study, it ... 2004 A synthetic lethal screen identifies a role for the cortical actin patch/endocytosis complex in the response to nutrient ...
Presenilin-Based Genetic Screens in Drosophila melanogaster Identify Novel Notch Pathway Modifiers | Genetics
Le Borgne, R., A. Bardin and F. Schweisguth, 2005 The roles of receptor and ligand endocytosis in regulating Notch signaling. ... Parks, A. L., K. M. Klueg, J. R. Stout and M. A. Muskavitch, 2000 Ligand endocytosis drives receptor dissociation and ... Endocytosis of Delta bound to Notch could result in conformational changes in Notch necessary for its cleavage by ADAM/TACE ... In addition, endocytosis through a recycling endosome has been proposed as a mechanism for converting a Delta "pro-ligand" into ...
Integration of Self and Non-self Recognition Modulates Asexual Cell-to-Cell Communication in Neurospora crassa | Genetics
... which physically interacts with amphiphysins to recruit them to sites of endocytosis and exocytosis in S. cerevisiae (Prigent ...
Cumulative Mutations Affecting Sterol Biosynthesis in the Yeast Saccharomyces cerevisiae Result in Synthetic Lethality That Is...
Other categories of suppressor mutations were in genes involved in endocytosis (7%), ubiquitination (6%), and ∼5% each involved ...
New Positive Regulators of lin-12 Activity in Caenorhabditis elegans Include the BRE-5/Brainiac Glycosphingolipid Biosynthesis...
In Drosophila, endocytosis of DSL proteins is required for their signaling activity (Wang and Struhl 2004) and there may be a ... role for endocytosis of DSL proteins in certain situations in C. elegans as well (Tian et al. 2004). Although lin-12(d) alleles ...