Demyelination in rheumatic diseases | Journal of Neurology, Neurosurgery & Psychiatry
CP, cyclophosphamide. *LA, Lupus anticoagulant. *MP, methylprednisolone. *MRI, magnetic resonance imaging. *MS, multiple ...
Punctate enhancement in a patient with neurosarcoidosis: a challenging radiological pattern | Journal of Neurology,...
Cyclophosphamide with steroids was effective.. Conclusions Perivascular punctate enhancement on MRI has been described in a ...
Prediction of progression of interstitial lung disease in patients with systemic sclerosis: the SPAR model | Annals of the...
Cyclophosphamide versus placebo in scleroderma lung disease. N Engl J Med 2006;354:2655-66.doi:10.1056/NEJMoa055120 ... Mycophenolate versus cyclophosphamide for progressive interstitial lung disease associated with systemic sclerosis: a 2-year ... The European League Against Rheumatism (EULAR) recommended that cyclophosphamide (CYC) should be considered for the ... Mycophenolate mofetil versus oral cyclophosphamide in scleroderma-related interstitial lung disease (SLS II): a randomised ...
Ocular manifestations in systemic lupus erythematosus | British Journal of Ophthalmology
She received oral prednisone, methotrexate and intravenous cyclophosphamide. Initial visual acuity and visual acuity 8 years ... The effective immunosuppressive drugs include azathioprine, methotrexate, mycophenolate mofetil and cyclophosphamide. ... 80 Combination of rituximab and cyclophosphamide infusions employed early in the course of retinal vasculitis and vaso- ...
Tumour necrosis factor blockers do not increase overall tumour risk in patients with rheumatoid arthritis, but may be...
The occurrence of malignancies in patients with rheumatoid arthritis treated with cyclophosphamide. A controlled retrospective ...
Long-term stabilisation of myeloma with curcumin | BMJ Case Reports
However, neither cyclophosphamide nor plerixafor/GCSF priming were successful. A bone marrow biopsy revealed 50% myeloma cells ... started cyclophosphamide, thalidomide and dexamethasone (CTD) treatment. However, after a week, the patient was admitted with ...
Methotrexate in patients with moderate systemic lupus erythematosus (exclusion of renal and central nervous system disease) |...
... azathioprine or alkylating substances such as cyclophosphamide.3-10 In contrast with cyclophosphamide and azathioprine ... In lupus nephritis11-13 several well conducted studies have shown the benefit of cyclophosphamide and corticosteroids and this ... controlled trial on pulse methylprednisolone versus two different regimens of pulse cyclophosphamide. Lancet 340:741-744, . ... we would recommend the well established treatment with cyclophosphamide. ...
Biological monitoring of cyclophosphamide and ifosfamide in urine of hospital personnel occupationally exposed to cytostatic...
Excretion of cyclophosphamide ranged from 3.5 to 38 micrograms/24 h (mean 11.4 micrograms/24 h) urine, ifosfamide from 5 to ... Biological monitoring of cyclophosphamide and ifosfamide in urine of hospital personnel occupationally exposed to cytostatic ... Biological monitoring of cyclophosphamide and ifosfamide in urine of hospital personnel occupationally exposed to cytostatic ... Twenty four hour urine was collected on days when cyclophosphamide and/or ifosfamide were mixed, on average 3900 mg ...
Predicting improvement in diffuse scleroderma: lessons learnt | Annals of the Rheumatic Diseases
intravenous pulse cyclophosphamide in diffuse cutaneous systemic sclerosis) trial for stem cell transplantation versus ... Autologous hematopoietic stem cell transplantation vs intravenous pulse cyclophosphamide in diffuse cutaneous systemic ... were more likely to have benefit from cyclophosphamide treatment (as these patients were more apt to worsen on placebo).14 In ... cyclophosphamide had no upper limit of mRSS (inclusion criteria of mRSS of at least 15) and the mean baseline mRSS was 25-26.4 ...
Neurofilament light chain as a biomarker in neurological disorders | Journal of Neurology, Neurosurgery & Psychiatry
S32] A decrease in CSF NfL has been also observed in patients treated with alemtuzumab, cyclophosphamide, fingolimod, ...
ANCA-associated vasculitis
MMF is non-inferior to cyclophosphamide for achieving remission in people AAV, but results in higher relapse rate. Introduction ...
Efficacy and safety of immunosuppressive agents in the treatment of necrotising scleritis: a retrospective, multicentre study...
We divided patients into two groups: a group treated with cyclophosphamide (CYC group) and a group treated with other ISAs; ... Aim To investigate the efficacy and safety of cyclophosphamide and other immunosuppressive agents (ISAs) in the treatment of ... Conclusion The efficacy of cyclophosphamide in the treatment of necrotising scleritis was comparable with that of other ISAs. ...
Primary central nervous system lymphoma presenting with multiple myeloma-like clinical picture | Journal of Neurology,...
She received 4920 cGy radiotherapy to the whole cranium followed by COPP (cyclophosphamide, vincristine, procarbazine and ...
Table of contents | Thorax
An investigation of the chest radiographs in a controlled trial of busulphan, cyclophosphamide, and a placebo after resection ...
Certolizumab pegol plus methotrexate provides broad relief from the burden of rheumatoid arthritis: analysis of patient...
Impact of oral cyclophosphamide on health-related quality of life in patients with active scleroderma lung disease: results ...
Incidence of malignancy in patients treated for antineutrophil cytoplasm antibody-associated vasculitis: follow-up data from...
... might reflect less extensive use of cyclophosphamide in current treatment protocols. Longer follow-up data are warranted to ...
Long-term outcome in polymyositis and dermatomyositis | Annals of the Rheumatic Diseases
Drugs used included azathioprine (n = 72), methotrexate (n = 41), ciclosporin (n = 15), cyclophosphamide (n = 6), intravenous ...
Efficacy and safety of atacicept for prevention of flares in patients with moderate-to-severe systemic lupus erythematosus (SLE...
Patients were excluded if they had taken any cyclophosphamide, mycophenolate mofetil (MMF), calcineurin inhibitors, leflunomide ...
Efficacy and safety of atacicept for prevention of flares in patients with moderate-to-severe systemic lupus erythematosus (SLE...
Patients were excluded if they had taken any cyclophosphamide, mycophenolate mofetil (MMF), calcineurin inhibitors, leflunomide ...
Daratumumab for the treatment of refractory ANCA-associated vasculitis | RMD Open
Rituximab versus cyclophosphamide for ANCA-associated vasculitis. N Engl J Med 2010;363:221-32.doi:10.1056/NEJMoa0909905pmid: ... Despite treatment with cyclophosphamide and rituximab, he never reached remission. At the time of evaluation for daratumumab ... Previous induction therapies with cyclophosphamide (CYC), rituximab (RTX) and plasma exchange (PEX) did not lead to clinical ... Both patients had persistently high ANCA levels despite induction treatment with both rituximab and cyclophosphamide. As ANCAs ...
Phase II, randomised, double-blind, multicentre study evaluating the safety and efficacy of filgotinib and lanraplenib in...
Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis. N Engl J Med 2005;353:2219-28.doi:10.1056/ ... Randomized, controlled trial of prednisone, cyclophosphamide, and cyclosporine in lupus membranous nephropathy. J Am Soc ... Prior studies support the use of prednisone, azathioprine, mycophenolate mofetil, cyclophosphamide, cyclosporine, chlorambucil ... cyclophosphamide or chlorambucil) for at least six consecutive months within 1 year before screening. Oral glucocorticoids were ...
Long-term patient survival in ANCA-associated vasculitis | Annals of the Rheumatic Diseases
... and the implementation of combined oral pulse steroid/cyclophosphamide association as a first-line strategy for induction ( ...
Refractory adult onset Still's disease successfully treated with anakinra | Annals of the Rheumatic Diseases
... cyclophosphamide, sulfasalazine, and ciclosporin A6-,8 have been used. Over the past years, several cases of successful ...
Factors associated with COVID-19-related death in people with rheumatic diseases: results from the COVID-19 Global Rheumatology...
... cyclophosphamide, ciclosporin, mycophenolate or tacrolimus: 2.22, 1.43 to 3.46, in the overall model; 2.44, 1.06 to 5.65, in ... cyclophosphamide, ciclosporin, mycophenolate or tacrolimus: 2.22, 1.43 to 3.46) and not receiving any disease-modifying anti- ... cyclophosphamide, ciclosporin, mycophenolate mofetil/mycophenolic acid, tacrolimus) as recommended by Isaacs and Burmester15; ...
EULAR recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases | Annals of the...
... particularly cyclophosphamide, azathioprine and leflunomide82,-,85 ,90 ,91 ,98 but not MTX.100 One study found an increased ...
Continuous renal replacement therapy in cytokine release syndrome following immunotherapy or cellular therapies? | Journal for...
Results of a 2-arm, phase 2 clinical trial using post-transplantation cyclophosphamide for the prevention of graft-versus-host ... Graft versus host disease prophylaxis was performed with cyclophosphamide in days 3 and 4 posttransplant and with Prograf and ...
Zostavax can be used in stable Lupus - Rheumatology Patient Summaries
... or any dose of cyclophosphamide or a biological medicine. ...
Early proteinuria response: a valid real-life situation predictor of long-term lupus renal outcome in an ethnically diverse...
Mycophenolate mofetil versus cyclophosphamide for induction treatment of lupus nephritis. J Am Soc Nephrol 2009;20:1103-12.doi: ... Moderators view: cyclophosphamide in lupus nephritis. Nephrol Dial Transplant 2016;31:1058-61.doi:10.1093/ndt/gfw067 ... Treatment of lupus nephritis with abatacept: the Abatacept and Cyclophosphamide Combination Efficacy and Safety Study. ... a randomized trial of low-dose versus high-dose intravenous cyclophosphamide. Arthritis Rheum 2002;46:2121-31.doi:10.1002/art. ...
959 Safety and anti-tumor activity of TCR-engineered autologous, PRAME-directed T cells across multiple advanced solid cancers...
After lymphodepletion with fludarabine and cyclophosphamide, T cells are infused, followed by low-dose IL-2. The primary ...