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*  Effect of Double Dose of Alpha 1-antitrypsin Augmentation Therapy on Lung Inflammation. - Full Text View - ClinicalTrials.gov
Drug: Alpha-1 Antitrypsin (human) Comparison of Zemaira (Alpha 1 Antitrypsin Human) 120 mg/kg/weekly for four weeks versus 2 ... Effect of Double Dose of Alpha 1-antitrypsin Augmentation Therapy on Lung Inflammation.. This study has been completed. ... Drug Information available for: alpha 1-Antitrypsin Genetic and Rare Diseases Information Center resources: Alpha-1 Antitrypsin ... Augmentation therapy in alpha-1 antitrypsin deficiency: advances and controversies. Ther Adv Respir Dis. 2010 Oct;4(5):289-312 ...
  https://clinicaltrials.gov/ct2/show/NCT01669421?recr=Open&cond=%22alpha+1-Antitrypsin+Deficiency%22&rank=9
*  The incidence of alpha-1-antitrypsin (A1AT) deficiency alleles in population of Central Poland - preliminary results from...
alpha-1 antitrypsin deficiency. S allele. Z allele. genotyping. blood concentration. DBS. prevalence. newborns. Poland. ... Inherited alpha-1 antitrypsin deficiency (A1ATD) is listed among the three most common genetic disorders in Caucasians. It ... Inherited alpha-1 antitrypsin deficiency (A1ATD) is listed among the three most common genetic disorders in Caucasians. It ... The incidence of alpha-1-antitrypsin (A1AT) deficiency alleles in population of Central Poland - preliminary results from ...
  https://journals.viamedica.pl/advances_in_respiratory_medicine/article/view/27565
*  Serum Proteins Associated with Emphysema Progression in Severe Alpha-1 Antitrypsin Deficiency<...
Serum proteins associated with emphysema progression in severe alpha-1 antitrypsin deficiency. ... 7. Survival and FEV1 decline in individuals with severe deficiency of alpha1-antitrypsin. The Alpha-1-Antitrypsin Deficiency ... Abbreviations: alpha-1 antitrypsin deficiency, AATD; chronic obstructive pulmonary disease, COPD; protease inhibitor ZZ, PiZZ; ... Running Head: Serum Proteins with Emphysema in Alpha-1. Funding Support: The QUANTUM-1 Study was supported by the National ...
  https://journal.copdfoundation.org/jcopdf/id/1160/Serum-Proteins-Associated-with-Emphysema-Progression-in-Severe-Alpha-1-Antitrypsin-Deficiency
*  Safety and Pharmacokinetics of Alpha-1 Proteinase Inhibitor in Subjects With Alpha1-Antitrypsin Deficiency - Full Text View -...
Emphysema Alpha 1-antitrypsin Deficiency (AATD) Biological: Prolastin-C, 60 mg/kg Biological: Prolastin-C, 120 mg/kg Phase 2 ... If receiving alpha-1 PI augmentation therapy, be willing to discontinue the treatment for the duration of the study ... alpha 1-antitrypsin. alpha 1-antitrypsin deficiency (AATD). alpha 1-proteinase inhibitor (Alpha-1 PI). ... MedlinePlus related topics: Alpha-1 Antitrypsin Deficiency Emphysema Drug Information available for: alpha 1-Antitrypsin ...
  https://clinicaltrials.gov/ct2/show/NCT01213043
*  Serum Elastase Activity, Serum Elastase Inhibitors, and Occurrence of Carotid Atherosclerotic Plaques | Circulation
The role of alpha 1-antitrypsin deficiency in the pathogenesis of immune disorders. Clin Immunol Immunopathol. 1985; 35: 363- ... The age- and sex-adjusted ORs for quartile 1 (lowest values), quartiles 2 to 3, and quartile 4 (highest values) of serum ... The major source of the elastase inhibitors determined in this investigation was α1-proteinase inhibitor and, to a lesser ... The occurrence of carotid plaques in subjects with the lowest serum elastase activity values (quartile 1), in those with the ...
  http://circ.ahajournals.org/content/105/22/2638
*  Pancreatic elastase - Wikipedia
Alpha 1-antitrypsin and alpha-2-macroglobulin are human serum protease inhibitors that completely inhibit the general ... Pancreatic elastase 1 is a serine endopeptidase, a specific type of protease that has the amino acid serine at its active site ... Elastase 1 is slightly inhibited above 150 mM NaCl Mutations of the CELA1 gene were suspected to be associated with diffuse ... 12 (1): 170-6. doi:10.1111/j.1432-1033.1970.tb00835.x. PMID 5461547. "CELA1 Gene". GeneCards. Davies RL, Yoon SJ, Weissenbach J ...
  https://en.wikipedia.org/wiki/Pancreatic_elastase
*  Alpha-1 antitrypsin deficiency - Genetics Home Reference
Alpha1-antitrypsin deficiency. 2: genetic aspects of alpha(1)-antitrypsin deficiency: phenotypes and genetic modifiers of ... Alpha-1 antitrypsin deficiency is an inherited disorder that may cause lung disease and liver disease. The signs and symptoms ... People with alpha-1 antitrypsin deficiency usually develop the first signs and symptoms of lung disease between ages 20 and 50 ... Alpha-1 antitrypsin deficiency is not a rare disease but a disease that is rarely diagnosed. Environ Health Perspect. 2003 Dec; ...
  https://ghr.nlm.nih.gov/condition/alpha-1-antitrypsin-deficiency
*  Alpha-1 antitrypsin - Wikipedia
DeMeo DL, Silverman EK (March 2004). "Alpha1-antitrypsin deficiency. 2: genetic aspects of alpha(1)-antitrypsin deficiency: ... Recombinant alpha-1 antitrypsin is not yet available for use as a drug but is under investigation as a therapy for alpha-1 ... Alpha-1-antitrypsin or α1-antitrypsin (A1AT, A1A, or AAT) is a protein belonging to the serpin superfamily. It is encoded in ... The alpha region can be further divided into two sub-regions, termed "1" and "2". Alpha-1 antitrypsin is the main protein of ...
  https://en.wikipedia.org/wiki/Alpha-1_antitrypsin
*  Alpha-1 Antitrypsin
... tests help diagnose alpha-1 antitrypsin deficiency. ... Alpha-1 antitrypsin (AAT) is a protein that protects the lungs from damage caused by activated enzymes. ... Antitrypsin_Deficiency/article.htm.. Alpha-1-Antitrypsin and Alpha-1-Antitrypsin Phenotype. ARUP's Guide to Clinical Laboratory ... Alpha-1 antitrypsin testing may be ordered when:. *An infant has jaundice that lasts for more than a week or two, an enlarged ...
  https://labtestsonline.org/tests/alpha-1-antitrypsin
*  What Is Alpha-1 Antitrypsin Deficiency Disorder? - Scientific American
What is alpha-1 antitrypsin deficiency?. It is a genetic defect in the production of a protective protein called alpha-1 ... If Jackson has alpha-1 antitrypsin deficiency, it means he cannot protect his lungs from his body's own defenses against ... What Is Alpha-1 Antitrypsin Deficiency Disorder?. An unauthorized biographer claims that pop star Michael Jackson is suffering ... What Is Alpha-1 Antitrypsin Deficiency Disorder?An unauthorized biographer claims that pop star Michael Jackson is suffering ...
  https://www.scientificamerican.com/article/michael-jackson-alpha-1-antitryps/
*  Alpha 1 Antitrypsin Deficiency Clinical Research Trials | CenterWatch
Alpha 1 Antitrypsin Deficiency Clinical Research Trial Listings in Gastroenterology Pulmonary/Respiratory Diseases Hepatology ( ... Alpha 1 Antitrypsin Deficiency Clinical Trials. A listing of Alpha 1 Antitrypsin Deficiency medical research trials actively ... Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human) Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema ... double blind clinical study to assess the efficacy and safety of two separate dose regimens of Alpha-1 MP versus placebo for ...
  https://www.centerwatch.com/clinical-trials/listings/condition/258/alpha-1-antitrypsin-deficiency/?&phase=3
*  Alpha 1 Antitrypsin Deficiency Clinical Research Trials | CenterWatch
Alpha 1 Antitrypsin Deficiency Clinical Research Trial Listings in Gastroenterology Pulmonary/Respiratory Diseases Hepatology ( ... Alpha-1 Antitrypsin Deficiency occurs when there is a lack of a protein in the blood called alpha-1 antitrypsin, or AAT. AAT is ... Alpha-1 Foundation Research Registry The Registry was established in 1997 by the Alpha-1 Foundation to facilitate research ... Alpha-1 Coded Testing(ACT) Study Genetic testing for alpha-1 antitrypsin deficiency is sometimes delayed despite established ...
  https://www.centerwatch.com/clinical-trials/listings/condition/258/alpha-1-antitrypsin-deficiency/?page=1
*  Alpha-1 antitrypsin deficiency - SNPedia
Depending on the genetic variant, alpha-1 antitrypsin deficiency can lead to chronic obstructive pulmonary disease (COPD) or ... SNPs associated with reduced levels of the enzyme alpha-1 antitrypsin (encoded by the SERPINA1 gene): ... Retrieved from "https://www.SNPedia.com/index.php?title=Alpha-1_antitrypsin_deficiency&oldid=1298471" ...
  https://www.snpedia.com/index.php/Alpha-1_antitrypsin_deficiency
*  Alpha-1 Antitrypsin Deficiency - Penn Medicine
Alpha-1 antitrypsin (A1AT) deficiency is a condition in which the body does not make enough of a protein that protects the ... a1-Antitrypsin deficiency and emphysema. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics ... a1-antitrypsin deficiency. Clin Chest Med. 2016;37(3):487-504. PMID: 27514595 www.ncbi.nlm.nih.gov/pubmed/27514595. ... AAT deficiency; Alpha-1 protease deficiency; COPD - alpha-1 antitrypsin deficiency; Cirrhosis - alpha-1 antitrypsin deficiency ...
  https://www.pennmedicine.org/for-patients-and-visitors/patient-information/conditions-treated-a-to-z/alpha-1-antitrypsin-deficiency
*  Alpha-1 Antitrypsin Deficiency
This program explains what alpha-1 antitrypsin deficiency is and what causes it. It also covers how AAT deficiency is diagnosed ... Alpha-1 Antitrypsin Deficiency. This program explains what alpha-1 antitrypsin deficiency is and what causes it. It also covers ...
  http://www.patient-education.com/english/topic/alpha-1-antitrypsin-deficiency
*  Alpha 1-antitrypsin deficiency overview --Doctors Lounge
Normally, alpha 1-antitrypsin is produced in the liver and exists in levels of 1.5-3.5 gram/litre. When the levels are reduced ... Alpha 1-antitrypsin deficiency (A1AD) is a genetic disorder caused by reduced levels of alpha 1-antitrypsin in blood. It leads ... Apart from increasing the inflammatory reaction in the airways, cigarette smoke also directly inactivates alpha 1-antitrypsin ... Please refer to the alpha 1-antitrypsin for the various protease inhibitor (Pi) genotypes and phenotypes. ...
  https://www.doctorslounge.com/index.php/reference/diseases/121
*  Anti-alpha 1 Antitrypsin antibody, prediluted (ab74664)
Rabbit polyclonal alpha 1 Antitrypsin antibody validated for IHC and tested in Human, Hrs, Mink, Mk and Bb. Immunogen ... Anti-alpha 1 Antitrypsin antibody, prediluted. See all alpha 1 Antitrypsin primary antibodies. ... Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - alpha 1 Antitrypsin antibody, prediluted (ab74664) ...
  http://www.abcam.com/alpha-1-antitrypsin-antibody-prediluted-ab74664.html
*  alpha-1-antitrypsin ELISA Kits | Biocompare.com
Compare alpha-1-antitrypsin ELISA Kits from leading suppliers on Biocompare. View specifications, prices, citations, reviews, ... Bovine Alpha-1-antitrypsin, SERPINA1 ELISA Kit *Detection Target: serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, ... SERPINA2 (Putative alpha-1-antitrypsin-related protein) BioAssay™ ELISA Kit (Human) *Detection Target: SERPINA2 (Putative alpha ... Your search returned 339 alpha-1-antitrypsin ELISA ELISA Kit across 25 suppliers. ...
  http://www.biocompare.com/pfu/110627/soids/2-36440/Assay_Kit/ELISA_alpha-1-antitrypsin
*  Alpha 1-antitrypsin deficiency - wikidoc
Template:Alpha-1 Antitrypsin deficiency Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mazia ... Differentiating Alpha 1-antitrypsin deficiency from other Diseases. Epidemiology and Demographics. Risk Factors. Screening. ... Mucolipidosis - I-cell disease - Pseudo-Hurler polydystrophy - Aspartylglucosaminuria - Fucosidosis - Alpha-mannosidosis - ... Mucopolysaccharidosis - 1:Hurler/Hunter - 3:Sanfilippo - 4:Morquio - 6:Maroteaux-Lamy - 7:Sly ...
  http://wikidoc.org/index.php/Alpha-1_antitrypsin_deficiency
*  Alpha-1 Antitrypsin Deficiency - NORD (National Organization for Rare Disorders)
Alpha-1 Antitrypsin Deficiency. NORD gratefully acknowledges James Stoller, MD, MS, Chairman and Jean Wall Bennett Professor of ... Alpha-1 antitrypsin is ordinarily released by specialized, granules within a type of white blood cells (called neutrophils or ... Alpha-1 antitrypsin deficiency (A1AD) is a disorder that occurs most frequently in Americans of Northern or Central European ... Alpha-1 antitrypsin deficiency (A1AD) is a hereditary disorder characterized by low levels of a protein called alpha-1 ...
  https://rarediseases.org/rare-diseases/alpha-1-antitrypsin-deficiency
*  Search of: 'alpha-1 antitrypsin deficiency' - List Results - ClinicalTrials.gov
Long Term Safety of Alpha1-Proteinase Inhibitor in Subjects With Alpha1 Antitrypsin Deficiency. *Pulmonary Emphysema in Alpha-1 ... GRADS Alpha-1. May 2013. June 2015. September 2015. April 16, 2013. January 12, 2016. *Arizona Health Sciences Center. Tucson, ... Alpha-1 Foundation. 22609. December 2013. August 2020. August 2021. December 18, 2013. January 18, 2018. *University of ... Alpha-1 Antitrypsin Deficiency Adult Liver Study. *Alpha-1 Antitrypsin Deficiency. *Procedure: Liver Biopsy (Biopsy Group Only) ...
  https://clinicaltrials.gov/ct2/results?cond=%22alpha-1+antitrypsin+deficiency%22&show_rss=Y
*  Anti-alpha 1 Antitrypsin antibody [B9] (ab9399) | Abcam
Mouse monoclonal alpha 1 Antitrypsin antibody [B9] validated for WB, ELISA, IHC and tested in Human. Referenced in 16 ... Western blot of alpha 1 antitrypsin using ab9399 at a concentration of 0.5 µ. g/ml. lane 2 - human plasma, 2 µ. l lane S - ... Western blot of alpha 1 antitrypsin using ab9399 at a concentration of 0.5 µg/ml. lane 2 - human plasma, 2 µl lane S - standard ... Anti-alpha 1 Antitrypsin antibody [B9]. See all alpha 1 Antitrypsin primary antibodies. ...
  https://www.abcam.com/alpha-1-antitrypsin-antibody-b9-ab9399.html
*  Alpha-1 antitrypsin deficiency and computed tomography findings.
... the severity of bronchiectasis and associated emphysema and the correlation with phenotype in patients with Alpha-1 antitrypsin ... Fourteen patients (54%) had a degree of dilatation score of 1 or more, all had a ZZ phenotype, and 4 (15%) had no evidence of ... The median forced expiratory volume in 1 second/forced vital capacity ratio was 43% (range: 24%-87%). A total of 156 lobes were ... investigate the severity of bronchiectasis and associated emphysema and the correlation with phenotype in patients with Alpha-1 ...
  http://www.biomedsearch.com/nih/Alpha-1-antitrypsin-deficiency-computed/16012317.html
*  Recombinant Human alpha 1 Antitrypsin protein (ab79181) Protocols
There are no specific protocols for Recombinant Human alpha 1 Antitrypsin protein (ab79181). Please download our general ...
  http://www.abcam.com/recombinant-human-alpha-1-antitrypsin-protein-ab79181-protocols.html