Population sub-structuring among Trypanosoma evansi stocks - Murdoch University Research Repository
Twenty-four multilocus genotypes were defined from the combination of alleles at the three loci. The Kenyan sub-populations ... We recorded a total of six alleles at the MORF2 locus, seven at 292 and 12 at the CRAM loci. Neis genetic distance showed ...
HLA-B*5701 typing: evaluation of an allele-specific polymerase chain reaction melting assay - Murdoch University Research...
In this study, we describe the development of such a method based on allele-specific polymerase chain reaction (AS-PCR) and ... 2007) HLA-B*5701 typing: evaluation of an allele-specific polymerase chain reaction melting assay. Tissue Antigens, 70 (1). pp ... Compared with sequence-based typing, this method had 100% sensitivity and specificity for the HLA-B*5701 allele. In conclusion ... HLA-B*5701 typing: evaluation of an allele-specific polymerase chain reaction melting assay ...
Correlates of protective cellular immunity revealed by analysis of population-level immune escape pathways in HIV-1 - Murdoch...
Differential CTL escape patterns between closely related HLA alleles were common and increased with greater evolutionary ... Characteristics associated with protective HLA alleles (defined using hazard ratios for progression to AIDS from natural ... distance between allele group members. Among 9-mer epitopes, mutations at HLA-specific anchor residues representedthe most ... I-associated polymorphisms identified at the population level mark viral sites under immune pressure by individual HLA alleles ...
Genetic polymorphism within HLA-A*02: significant allelic variation revealed in different populations - Murdoch University...
We have developed a method for determining the 14 Known alleles of HLA-A*02 by use of ARMS-PCR to determine the degree of ... Considerable variation was found in the relative frequencies of particular A*02 alleles between Caucasian, oriental and black ... and variation within the genes may influence the peptide binding specificity of the gene products of each allele. Failure to ... and emphasize the functional significance of allele supecific subtyping of HLA-A*02. ...
Publications: Zhang, Jingjuan - Murdoch University Research Repository
2013) Wild-type alleles of Rht-B1 and Rht-D1 as independent determinants of thousand-grain weight and kernel number per spike ... 2018) Associations of NAM-A1 alleles with the onset of senescence and nitrogen use efficiency under Western Australian ...
A variant of human aromatase predicts increased circulating estradiol and bone health in post-menopausal women - Murdoch...
CT, TT: 38.3 ± 27.4 pmol/L; P = 4.5 × 10− 21). In addition, the variant allele was associated with increased BMD at the total ... CT, TT: 21.1%; P = 0.012). We found that carriers of the T allele (17% of the population) show increased circulating estrogen, ...