Xeroderma Pigmentosum Group D Protein - Medical Dictionary online-medical-dictionary.org
Learn about Xeroderma Pigmentosum Group D Protein at online-medical-dictionary.org ... Group 2 Protein. Excision Repair Cross-Complementing Rodent Repair Deficiency, Group 2 Protein. Xeroderma Pigmentosum ... Xeroderma Pigmentosum Group D Protein. Synonyms. ERCC2 Protein. Excision Repair Cross Complementing Rodent Repair Deficiency, ... and mutations in this protein are associated with XERODERMA PIGMENTOSUM. ...
repE--the Dictyostelium homolog of the human xeroderma pigmentosum group E gene is developmentally regulated and contains a...
... a homolog of the human xeroderma pigmentosum (XP) group E gene which encodes a UV-damaged DNA binding protein. The repE gene ... a homolog of the human xeroderma pigmentosum (XP) group E gene which encodes a UV-damaged DNA binding protein. The repE gene ... repE--the Dictyostelium homolog of the human xeroderma pigmentosum group E gene is developmentally regulated and contains a ... The predicted protein encodes a leucine zipper motif. The repE gene is not expressed by mitotically dividing cells, and repE ...
Xeroderma pigmentosum - Wikipedia
"Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair". Molecular Cell. 2 ... Xeroderma pigmentosum was first described in the 1870s by Moritz Kaposi. In 1882, Kaposi coined the term xeroderma pigmentosum ... "Xeroderma Pigmentosum". NORD (National Organization for Rare Disorders). 2017. Retrieved 28 June 2018. "Xeroderma pigmentosum ... Xeroderma pigmentosum was first described in 1874 by Hebra and Moritz Kaposi. In 1882, Kaposi coined the term xeroderma ...
ERCC3 gene: MedlinePlus Genetics
The ERCC3 gene provides instructions for making a protein called XPB. Learn about this gene and related health conditions. ... xeroderma pigmentosum group B-complementing protein. *xeroderma pigmentosum, complementation group B. Additional Information & ... Xeroderma pigmentosum. At least one variant in the ERCC3 gene also appears to be a rare cause of xeroderma pigmentosum. This ... excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B ...
XPF Monoclonal Antibody (UMAB20) (UM500020CF)
Xeroderma pigmentosum group F-complementing protein; xeroderma pigmentosum, complementation group F ... protein binding protein C-terminus binding structure-specific DNA binding protein N-terminus binding nucleic acid binding DNA ... DNA repair protein complementing XP-F cells; Ercc4 protein-like; excision repair cross-complementation group 4; excision repair ... Protein Aliases: DNA excision repair protein ERCC-4; DNA repair endonuclease subunit; DNA repair endonuclease XPF; ...
斑馬魚胚胎中DNA結構變異辨識蛋白之
Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair. Mol. Cell. 2:223- ... Mutations specific to the xeroderma pigmentosum group E Ddb-phenotype. J. Biol. Chem. 271:24317-24320.. Nordberg, J., Arner, E. ... High mobility group proteins 1 and 2 recognize chromium-damaged DNA. Carcinogenesis. 18:371-375.. Wood, R.D. 1996. DNA repair ... High-mobility group 1 protein inhibits helicase catalyzed displacement of cisplatin-damaged DNA. Biochimica et Biophysica Acta ...
SMART: WD40 domain annotation
DNA damage-binding protein 2 (Q92466) (SMART). OMIM:600811: Xeroderma pigmentosum, group E, DDB-negative subtype. OMIM:278740: ... Repeated WD40 motifs act as a site for protein-protein or protein-DNA interaction, and proteins containing WD40 repeats are ... several proteins with WD-repeats are able to fold into globular proteins in a rabbit reticulocyte lysate. One protein, beta ... Maltose Binding Protein fusion with RACK1 from A. thaliana. 3dw8. Structure of a Protein Phosphatase 2A Holoenzyme with B55 ...
SMART: WD40 domain annotation
DNA damage-binding protein 2 (Q92466) (SMART). OMIM:600811: Xeroderma pigmentosum, group E, DDB-negative subtype. OMIM:278740: ... Repeated WD40 motifs act as a site for protein-protein or protein-DNA interaction, and proteins containing WD40 repeats are ... several proteins with WD-repeats are able to fold into globular proteins in a rabbit reticulocyte lysate. One protein, beta ... Maltose Binding Protein fusion with RACK1 from A. thaliana. 3dw8. Structure of a Protein Phosphatase 2A Holoenzyme with B55 ...
Xeroderma Pigmentosum: Background, Pathophysiology, Epidemiology
In 1882, Kaposi coined the term xeroderma pigmentosum for the condition, referring to its characteristic dry, pigmented skin. ... Xeroderma pigmentosum (XP) was first described in 1874 by Hebra and Kaposi. ... Patients with xeroderma pigmentosum complementation groups C, E and V do not have abnormal sunburn reactions. Br J Dermatol. ... In addition to their role in DNA repair, xeroderma pigmentosum proteins also have additional functions. For example, Fréchet et ...
Exploring new potential role of DDB2 by host cell reactivation assay in human tumorigenic cells | BMC Cancer | Full Text
In this work, we have investigated whether DDB2 protein may influence the repair of a UV-damaged DNA plasmid into the cellular ... Moreover, the co-localization between DDB2 proteins and different NER factors recruited at DNA damaged sites was analysed by ... as also confirmed by the different extent of co-localization of DDB2Wt and some NER proteins (such as XPG), vs the DDB2 mutant ... confirms itself as a very helpful approach to assess in the cellular context the effect of expressing mutant vs Wt NER proteins ...
Steffen SCHUBERT | Researcher | Dr. rer. nat. | Georg-August-Universität Göttingen, Göttingen | GAUG | Information Network of...
The xeroderma pigmentosum (XP) group D protein is involved in nucleotide excision repair (NER) as well as in basal ... Seven xeroderma pigmentosum (XP) complementation groups (XP-A to XP-G) according to the respective mutated genes (XPA-XPG) and ... Patients belonging to xeroderma pigmentosum (XP) complementation group C comprise one-third of all XP patients. Only four major ... Defects in these two proteins result in severe diseases like xeroderma pigmentosum (XP). We applied our newly CRISPR/Cas9 ...
Orphanet: ERCC excision repair 3, TFIIH core complex helicase subunit
... xeroderma pigmentosum group B complementing, XPB. *Previous symbols and names : excision repair cross-complementation group 3, ... excision repair cross-complementing rodent repair deficiency, complementation group 3. *Type : gene with protein product ... in Xeroderma pigmentosum ORPHA:910. *Disease-causing germline mutation(s) in Xeroderma pigmentosum-Cockayne syndrome complex ...
ERCC5 - Early...
Xeroderma pigmentosum group G-complementing protein. *excision repair cross-complementing rodent repair deficiency, ... Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma ... xeroderma pigmentosum, complementation group G. Description. The ERCC5 gene encodes a single-stranded structure-specific DNA ... The ERCC5 protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription- ...
Mouse Models for Xeroderma Pigmentosum Group A and Group C Show Divergent Cancer Phenotypes | Cancer Research | American...
Sugasawa K. The xeroderma pigmentosum group C protein complex and ultraviolet-damaged DNA-binding protein: functional assays ... the Xeroderma pigmentosum group C (XPC) and group A (XPA) proteins are involved. To elucidate differences in the functions of ... Mouse Models for Xeroderma Pigmentosum Group A and Group C Show Divergent Cancer Phenotypes Joost P.M. Melis; Joost P.M. Melis ... Yokoi M, Masutani C, Maekawa T, Sugasawa K, Ohkuma Y, Hanaoka F. The xeroderma pigmentosum group C protein complex XPC-HR23B ...
Frontiers | The Influence of miRNAs on Radiotherapy Treatment in Prostate Cancer - A Systematic Review
... xeroderma pigmentosum complementation group C (XPC), and KU80 proteins. Also, Hatano et al. revealed that miRNA-744-3p can ... This miRNA is related with prostate transmembrane protein, androgen-induced l(PMEPA1), and tumor protein p53 inducible nuclear ... described that miRNA-145 mimics can silence and deregulate the Speckle-type pox virus and zinc finger protein (POZ) protein ( ... protein kinase C epsilon (PKCϵ) and ZEB1 expression, proteins involved in EMT (40). In the same context, miRNA-30a has been ...
xeroderma pigmentosum, complementation group C (XPC) | The Digital Ageing Atlas
The Mechanisms of Current Platinum Anticancer Drug Resistance in the Glioma | Bentham Science
Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair. Mol Cell 1998; 2(2 ... Liu X, Sun K, Wang H, Dai Y. Knockdown of retinoblastoma protein may sensitize glioma cells to cisplatin through inhibition of ... Overexpression of long non-coding RNA differentiation antagonizing non-protein coding RNA inhibits the proliferation, migration ... complexes incorporating straight-chain aliphatic diamine linker groups. J Med Chem 1992; 35(24): 4526-32.. [http://dx.doi.org/ ...
SMART: Secondary literature for BHD 2 domain
... the XPC protein, must bind to the damaged DNA site. The UV-damaged DNA-binding protein (UV-DDB), which is impaired in XP group ... Defects in NER are associated with several human genetic disorders including xeroderma pigmentosum (XP), which is characterized ...
DeCS
Xeroderma Pigmentosum Group D Protein [D08.811.277.040.025.159.500] Xeroderma Pigmentosum Group D Protein ... Minichromosome Maintenance Proteins - Preferred Concept UI. M0579688. Scope note. A family of proteins that were originally ... MCM Protein Complex - Narrower Concept UI. M0579691. Scope note. A hexameric protein complex of minichromosome maintenance ... Xeroderma Pigmentosum Group D Protein [D08.811.399.340.500] Xeroderma Pigmentosum Group D Protein ...
Profile - Publications | Scholars@IU
Design and Structure-Guided Development of Novel Inhibitors of the Xeroderma Pigmentosum Group A (XPA) Protein-DNA Interaction ... Abstract C58: Small molecule inhibitors targeting the interaction of xeroderma pigmentosum group A protein with cisplatin- ... Multiple protein-protein interactions within the DNA-PK complex are mediated by the C-terminus of Ku 80.. Bennett, Sara M⋅Woods ... Exploring a structural protein-drug interactome for new therapeutics in lung cancer.. Peng, Xiaodong⋅Peng, Xiaodong⋅Peng, ...
Cep135 Mouse Gene Details | centrosomal protein 135 | International Mouse Phenotyping Consortium
Xeroderma Pigmentosum, Complementation Group G. Microphthalmia. OMIM:278780. Congenital Primary Aphakia. Microphthalmia, ... increased circulating total protein level Cep135em1(IMPC)J HET Late adult 9.67×10-05 ... Abnormal circulating protein concentration, Abnormal circulating albumin concentration. ORPHA:86839. Intellectual Disability- ... Abnormal circulating protein concentration, Abnormal circulating polysaccharide concentration, Hy.... ORPHA:103910. ...
Resisting Cancer | The Scientist Magazine®
Xeroderma pigmentosum, for example, stems from a specific DNA repair deficiency. The predominant form of this condition is ... Yet another group of genes associated with cancer formation regulates programmed cell death, or apoptosis. The normal function ... Adherens junctions, protein complexes that occur at cell-cell points of contact in epithelial and endothelial tissues, appear ... Patients with xeroderma pigmentosum must protect themselves from sunlight all their lives, but they nevertheless develop ...
Modified FOLFOX-6 chemotherapy in advanced gastric cancer: Results of phase II study and comprehensive analysis of...
... xeroderma pigmentosum group D (XPD, also known as ERCC2) and X-ray repair cross-complementing group (XRCC), have important ... TS protein expressions were determined by Western immunoblotting, as previously described [36]. Equivalent amounts of protein ... Park DJ, Stoehlmacher J, Zhang W, Tsao-Wei DD, Groshen S, Lenz HJ: A Xeroderma pigmentosum group D gene polymorphism predicts ... Six bp deletion homozygotes tended to show lower TS protein expression (TS/tubulin expression ratio 0.88 in -6 bp/-6 bp vs. ...
Genomic Sciences - Works - Citation Index - NCSU Libraries
Xeroderma Pigmentosum Group A Protein / biosynthesis; Xeroderma Pigmentosum Group A Protein / genetics ... Antimicrobial Use Guidelines for Treatment of Urinary Tract Disease in Dogs and Cats: Antimicrobial Guidelines Working Group of ... MeSH headings : Adolescent; Animals; Bacterial Outer Membrane Proteins / genetics; Doxycycline / therapeutic use; Humans; Male ... author keywords: Mite; Acari; Phytoseiidae; Transcriptome; 454; Vitellogenin; Vitellin; Yolk protein; Vitellogenin receptor; ...
Genes search | AnalogYeast
Xeroderma pigmentosum group B-complementing protein). 3.6.4.12 Homo sapiens Cerebro-Oculo-Facio-Skeletal Syndrome,Ichthyosis, ... Xeroderma Pigmentosum, Complementation Group C,Xeroderma Pigmentosum, Complementation Group D,Xeroderma Pigmentosum, Variant ... Xeroderma Pigmentosum, Complementation Group F,Xeroderma Pigmentosum, Complementation Group G,Skin Carcinoma,Xeroderma ... Xeroderma Pigmentosum, Complementation Group C,Xeroderma Pigmentosum, Variant Type,Fanconi Anemia, Complementation Group A, ...
Comparison of cancer stem cell enrichment between spheroids derived from single-cell and multicellular aggregate cultures ...
Xeroderma Pigmentosum Complementation Group C.. Acknowledgments The authors express their gratitude to the staff and students ... such as tight junction protein ZO-1 and cellular adhesion protein E-cadherin45, 46. These proteins play significant roles in ... Forkhead box protein A1, GAPDH: Glyceraldehyde 3-Phosphate Dehydrogenase, GATA3: GATA Binding Protein 3, GC: Gemcitabine and ... Lee Y.C., Tsai K.W., Liao J.B., Kuo W.T., Chang Y.C., Yang Y.F., High expression of tight junction protein 1 as a predictive ...
Christopher G Bunick | Specialists | Yale Medicine
Biochemical and structural domain analysis of xeroderma pigmentosum complementation group C protein. Biochemistry 2006, 45: ... Biochemical and structural domain analysis of xeroderma pigmentosum complementation group C protein. Biochemistry 2006, 45: ... Biochemical and structural domain analysis of xeroderma pigmentosum complementation group C protein. ... Biochemical and structural domain analysis of xeroderma pigmentosum complementation group C protein. ...
is an opportunistic fungi leading to severe pneumonia in immune-compromised hosts. - PARG inhibitors in cancer therapy
Previous post The xeroderma pigmentosum group E gene product DDB2 a protein involved ... associated proteins kinase (ZAP70) and activation from the downstream kinase calcium/calmodulin-dependent proteins kinase type ... offers since been defined as encoding a proteins that acts mainly because a poor regulator of meiosis by phosphorylating and ... 23 31 32 Therefore both of these genes encode the protein central for the initiation and modulation of meiosis in was ...
Amit Joshi, M.B.,B.S., Ph.D. | Harvard Catalyst Profiles | Harvard Catalyst
Browsing Temel Eczacılık Bilimleri Bölümü Makale Koleksiyonu by Issue Date
Xeroderma Pigmentosum Complementation Group E Protein (Xpe/Ddb2): Purification Of Various Complexes Of Xpe And Analyses Of ... Xeroderma pigmentosum is characterized by increased sensitivity of the affected individuals to sunlight and light-induced skin ... Misincorporation Of Free M-Tyrosine Cytotoxic Mechanism For Oxidized A Into Cellular Proteins: A Potential Amino Acids Gurer- ... Dejgaard, S; Ortapamuk, O; Ozer, I (Harwood Acad Publ Gmbh, Taylor & Francis Group, 1999) ...