Wiskott-Aldrich syndrome (WAS) is an X-linked recessive disorder originally described as a clinical triad of thrombocytopenia, ... WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally ... Other Medscape Reference articles on Wiskott-Aldrich syndrome include Wiskott-Aldrich Syndrome and Pediatric Wiskott-Aldrich ... of carrier status for the Wiskott-Aldrich syndrome by flow cytometric analysis of Wiskott-Aldrich syndrome protein expression ...
Wiskott-Aldrich syndrome protein family member 3 is a protein that in humans is encoded by the WASF3 gene. This gene encodes a ... member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that ... Millard TH, Machesky LM (2001). "The Wiskott-Aldrich syndrome protein (WASP) family". Trends Biochem. Sci. 26 (3): 198-9. doi: ... "Entrez Gene: WASF3 WAS protein family, member 3". Jones GE (2000). "Cellular signaling in macrophage migration and chemotaxis ...
Wiskott-Aldrich Syndrome protein family. * VEGA ID. OTTHUMG00000157346 Gene info. * Identity. HGNC:6868 ... Ask Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder ... Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder ...
Wiskott-Aldrich syndrome (see the image below) is an X-linked recessive immunodeficiency disorder characterized in one third of ... X-linked thrombocytopenia in two unrelated families is associated with point mutations in the Wiskott-Aldrich syndrome protein ... encoded search term (Pediatric Wiskott-Aldrich Syndrome) and Pediatric Wiskott-Aldrich Syndrome What to Read Next on Medscape ... The expression of Wiskott-Aldrich syndrome protein (WASP) is dependent on WASP-interacting protein (WIP). Int Immunol. 2007 Feb ...
A scientific resource for the EVH1 protein domain containing information on structure, function, and binding to a proline-rich ... in the WASP docking protein altered in the immunodeficiency Wiskott-Aldrich syndrome, and in the Homer family of synaptic ... and the closely related protein Vasp. EVH1. domains are also found in another Mena family protein (Evl), ... Examples of Domain Proteins. Binding Examples. EVH1 Containing Proteins. Binding Partners. Motif. ...
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of ... Neural Wiskott-Aldrich syndrome protein; Wiskott-Aldrich syndrome like; Wiskott-Aldrich syndrome-like ... response to bacterium actin filament polymerization regulation of protein localization cellular protein complex localization ... and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate ...
Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP- ... General protein information Go to the top of the page Help Preferred Names. WD repeat and coiled-coil-containing protein. Names ... mRNA and Protein(s) * NM_001142319.2 → NP_001135791.1 WD repeat and coiled-coil-containing protein isoform 2 ... WD repeat and coiled-coil-containing protein C2orf44. WD repeat-containing protein C2orf44. ...
Wiskott-Aldrich Syndrome Protein Family 28% * Integration of RhoGTPase signaling during macrophage migration. Cox, D., Hodgson ... Tools for Exceptional Overexpression and Structural Stabilization of Membrane Proteins in Mammalian Cells. Steinmetz, E. J., ... Tools for Exceptional Overexpression and Structural Stabilization of Membrane Proteins in Mammalian Cells. Snapp, E. L., ... Fluorescent probes for quantitation of secretory protein levels in single cells. Snapp, E. L. & Levy, M. ...
The scaffolding protein WAVE-1 (Wiskott-Aldrich syndrome protein family member 1) directs signals from the GTPase Rac through ... N2 - The scaffolding protein WAVE-1 (Wiskott-Aldrich syndrome protein family member 1) directs signals from the GTPase Rac ... AB - The scaffolding protein WAVE-1 (Wiskott-Aldrich syndrome protein family member 1) directs signals from the GTPase Rac ... abstract = "The scaffolding protein WAVE-1 (Wiskott-Aldrich syndrome protein family member 1) directs signals from the GTPase ...
... roles of the DOCK family proteins in linking phosphoinositide signaling to specific Rho-Wiskott-Aldrich syndrome protein family ... Wiskott-Aldrich syndrome protein (WASP) is a Cdc42 effector that stimulates Arp2/3 complex-mediated actin polymerization, and ... 2013) Dedicator of cytokinesis 8 interacts with talin and Wiskott-Aldrich syndrome protein to regulate NK cell cytotoxicity. J ... P2 serve as the coincidence detection signals for activation of Wiskott-Aldrich syndrome protein, which stimulates Arp2/3 ...
Antioxidant Dieckol Downregulates the Rac1/ROS Signaling Pathway and Inhibits Wiskott-Aldrich Syndrome Protein (WASP)-Family ... Bone Morphogenetic Protein 9 Overexpression Reduces Osteosarcoma Cell Migration and Invasion. Zilan Lv, Dandan Yang, Jie Li, ... Specificity Protein 1 Expression Contributes to Bcl-w-Induced Aggressiveness in Glioblastoma Multiforme. Woo Sang Lee, Junhye ... Identification of Proteins Differentially Expressed in Gastric Cancer Cells with High Metastatic Potential for Invasion to ...
Antioxidant Dieckol Downregulates the Rac1/ROS Signaling Pathway and Inhibits Wiskott-Aldrich Syndrome Protein (WASP)-Family ... Kinetics of Binding of LPS to Recombinant CD14, TLR4, and MD-2 Proteins. Han Jae Shin, Hayyoung Lee, Jong Dae Park, Hak Chul ... Regulation of IkappaB Kinase by GβL through Recruitment of the Protein Phosphatases. Dong-Joo You, You Lim Kim, Cho Rong Park, ... Transduced Tat-DJ-1 Protein Protects against Oxidative Stress-Induced SH-SY5Y Cell Death and Parkinson Disease in a Mouse Model ...
Among these proteins, WASL and STK10 proteins showed a gradual decrease in expression with age, and WNK1 protein showed a ... Analyzing the data of urine exosome proteomics, a total of 12 lymphocyte related proteins were identified, 5 of which were ... Lung cancer patients had reduced expression of WASL and increased expression of STK10 and WNK1 proteins in urine exosomes ... But changes in the expression of lymphocyte migration regulation related proteins in urine exosomes remain unclear. This study ...
... through proteins in the Wiskott-Aldrich syndrome protein (WASP) family to the actin nucleating machine, the Arp2/3 complex. In ... One protein that quickly came to mind was the well-known WASP ligand, Nck. This adaptor protein is composed of an SH2 domain, ... insoluble aggregates of unfolded proteins. As an NMR lab often working with highly concentrated protein solutions, we had ... In the case of Nck and N-WASP, the SH2 domain of Nck was known to bind many proteins that contain multiple sites of tyrosine ...
Wiskott-Aldrich syndrome protein family verprolin-homologous domain-containing protein 3 (WAVE3) is reported as an oncogene ... receptor interacting protein kinase 3 (RIP3), receptor interacting protein kinase 3 (MLKL), protein kinase B (Akt), Nuclear ... The 24-kDa protein (p24) encoded by Grapevine leafroll-associated virus 2 (GLRaV-2) is an RNA-silencing suppressor (RSS), but ... Protein expression levels of related molecular markers were quantitated by western blot analysis. The levels of ROS, NO, and ...
Wiskott-Aldrich syndrome protein)-family verprolin-homologous protein] regulatory complex which is thought to be activated at ... 2011 This led to our discovery that Arf family GTPases directly recruit and activate the WRC which is enhanced when Arf and ... Here we sought to demonstrate that Arf family GTPases play a role in WRC-dependent generation of lamellipodia. Results and ... The mammalian Arf GTPase family is also divergent and can be divided into three subfamilies: Class 1 Cinnamaldehyde (Arf1 Arf3 ...
... and bind directly to WAVE proteins [Wiskott-Aldrich syndrome protein (WASP) family Verprolin-homologous proteins] via their DHR ... family of guanine nucleotide exchange factors (GEFs). This protein, dedicator of cytokinesis 3 (DOCK3), is also known as ... family of guanine nucleotide exchange factors (GEFs). This protein, dedicator of cytokinesis 3 (DOCK3), is also known as ... Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 3 (DOCK3) in samples from cell ...
Wiskott-Aldrich Syndrome Protein Family. *Molecular Motor Proteins. *Dyneins. *Kinesin. *Myosins. *Muscle Proteins ... A diverse superfamily of proteins that function as translocating proteins. They share the common characteristics of being able ...
Wiskott-Aldrich Syndrome Protein Family [D05.750.078.730.912] * Amino Acids, Peptides, and Proteins [D12] * Proteins [D12.776] ... Cytoskeletal Proteins [D12.776.220] * Microfilament Proteins [D12.776.220.525] * Actin Capping Proteins [D12.776.220.525.032] ... A complex of seven proteins including ARP2 PROTEIN and ARP3 PROTEIN that plays an essential role in maintenance and assembly of ... A complex of seven proteins including ARP2 PROTEIN and ARP3 PROTEIN that plays an essential role in maintenance and assembly of ...
Wiskott-Aldrich Syndrome Protein Family [D05.750.078.730.912] Wiskott-Aldrich Syndrome Protein Family ... Wiskott-Aldrich Syndrome Protein Family [D12.776.220.525.912] Wiskott-Aldrich Syndrome Protein Family ... N-terminal myristoylated protein that binds CALMODULIN and is a prominent substrate for PROTEIN KINASE C. Both phosphorylation ... N-terminal myristoylated protein that binds CALMODULIN and is a prominent substrate for PROTEIN KINASE C. Both phosphorylation ...
Wiskott-Aldrich Syndrome Protein Family. *Muscle Proteins. *Actinin. *Actins. *Actomyosin. *Calsequestrin. *CapZ Actin Capping ... A protein factor that regulates the length of R-actin. It is chemically similar, but immunochemically distinguishable from ... Iwakuma T, Agarwal N. MDM2 binding protein, a novel metastasis suppressor. Cancer Metastasis Rev. 2012 Dec; 31(3-4):633-40. ...
Wiskott-Aldrich Syndrome Protein Family. *Muscle Proteins. *Actinin. *Actins. *Actomyosin. *Calsequestrin. *CapZ Actin Capping ... A protein found in the thin filaments of muscle fibers. It inhibits contraction of the muscle unless its position is modified ...
Wiskott-Aldrich Syndrome Protein Family. *Molecular Motor Proteins. *Dyneins. *Kinesin. *Myosins. *Muscle Proteins ... A diverse superfamily of proteins that function as translocating proteins. They share the common characteristics of being able ...
Two novel mutations identified in the Wiskott-Aldrich syndrome protein gene cause Wiskott-Aldrich syndrome and thrombocytopenia ... Identification of WASP mutations in 10 Australian families with Wiskott-Aldrich syndrome and X-linked thrombocytopenia. ... Mutations of the Wiskott-Aldrich Syndrome Protein (WASP): hotspots, effect on transcription, and translation and phenotype/ ... Clinical aspects and genetic analysis of taiwanese patients with wiskott-Aldrich syndrome protein mutation: the first ...
Wiskott-Aldrich Syndrome Protein Wiskott-Aldrich Syndrome Protein Family Wiskott-Aldrich Syndrome Protein, Neuronal ... WASP Protein use Wiskott-Aldrich Syndrome Protein Wasp Venoms WASP-Family Verprolin Homologous Proteins use Wiskott-Aldrich ... Wilms Tumor-Aniridia-Gonadoblastoma-Mental Retardation Syndrome use WAGR Syndrome Wilson Disease use Hepatolenticular ... Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation Syndrome use WAGR Syndrome Wilms Tumor-Aniridia- ...
Wiskott-Aldrich Syndrome Protein Wiskott-Aldrich Syndrome Protein Family Wiskott-Aldrich Syndrome Protein, Neuronal ... WASP Protein use Wiskott-Aldrich Syndrome Protein Wasp Venoms WASP-Family Verprolin Homologous Proteins use Wiskott-Aldrich ... WAS Protein Family use Wiskott-Aldrich Syndrome Protein Family Wasabia Wash Basins use Sanitary Devices ... Wiskott-Aldrich Syndrome ... WAVE Proteins use Wiskott-Aldrich Syndrome Protein Family Waxes ...
Wiskott-Aldrich Syndrome Protein Wiskott-Aldrich Syndrome Protein Family Wiskott-Aldrich Syndrome Protein, Neuronal ... WASP Protein use Wiskott-Aldrich Syndrome Protein Wasp Venoms WASP-Family Verprolin Homologous Proteins use Wiskott-Aldrich ... WAS Protein Family use Wiskott-Aldrich Syndrome Protein Family Wasabia Wash Basins use Sanitary Devices ... Wiskott-Aldrich Syndrome ... WAVE Proteins use Wiskott-Aldrich Syndrome Protein Family Waxes ...
Wiskott-Aldrich Syndrome Protein Wiskott-Aldrich Syndrome Protein Family Wiskott-Aldrich Syndrome Protein, Neuronal ... WASP Protein use Wiskott-Aldrich Syndrome Protein Wasp Venoms WASP-Family Verprolin Homologous Proteins use Wiskott-Aldrich ... Wilms Tumor-Aniridia-Gonadoblastoma-Mental Retardation Syndrome use WAGR Syndrome Wilson Disease use Hepatolenticular ... Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation Syndrome use WAGR Syndrome Wilms Tumor-Aniridia- ...
Wiskott-Aldrich Syndrome Protein Wiskott-Aldrich Syndrome Protein Family Wiskott-Aldrich Syndrome Protein, Neuronal ... WASP Protein use Wiskott-Aldrich Syndrome Protein Wasp Venoms WASP-Family Verprolin Homologous Proteins use Wiskott-Aldrich ... Wilms Tumor-Aniridia-Gonadoblastoma-Mental Retardation Syndrome use WAGR Syndrome Wilson Disease use Hepatolenticular ... Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation Syndrome use WAGR Syndrome Wilms Tumor-Aniridia- ...
Wiskott-Aldrich Syndrome Protein Wiskott-Aldrich Syndrome Protein Family Wiskott-Aldrich Syndrome Protein, Neuronal ... WASP Protein use Wiskott-Aldrich Syndrome Protein Wasp Venoms WASP-Family Verprolin Homologous Proteins use Wiskott-Aldrich ... Wilms Tumor-Aniridia-Gonadoblastoma-Mental Retardation Syndrome use WAGR Syndrome Wilson Disease use Hepatolenticular ... Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation Syndrome use WAGR Syndrome Wilms Tumor-Aniridia- ...