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*  Increasing Clinical Virulence in Two Decades of the Italian HIV Epidemic
We investigated time trends of virulence in the Italian HIV epidemic and found increasing virulence. The use of an established ... Our results are consistent with the hypothesis of increasing HIV virulence; however, clinical virulence combines viral and host ... Of primary interest is whether the virulence of the virus, i.e. its ability to cause disease, has been changing over time. ... The comparisons revealed that genuine differences exist in the trends of HIV virulence between different epidemics. Thus, there ...
  http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1000454
*  HIV-1's high virulence might be an accident of evolution
... virulence_characteristic_of_hiv1the_virus_predominantly_responsible_for_human_aidsmight_amount_to_an_accident_of_evolution_new_ ... The virulence characteristic of HIV-1--the virus predominantly responsible for human AIDS--might amount to an accident of ...
  http://www.biologynews.net/archives/2006/06/15/hiv1s_high_virulence_might_be_an_accident_of_evolution.html
*  Evolution of virulence when transmission occurs before disease | Biology Letters
... high virulence is to be expected at the ESS virulence (figure 2). Thus it is reasonable to expect virulence to increase after ... the ESS virulence decreases. The degree of decrease in ESS virulence depends on the parameter scaling virulence relative to ... In contrast, ESS virulence first increased and then decreased with transition rate when there was little virulence early in the ... Thus, virulence may increase or decrease after pathogen emergence in the new host population. ESS virulence will be much larger ...
  http://rsbl.royalsocietypublishing.org/content/6/4/505
*  Expression profile of virulence associated MAP genes un | Open-i
Expression profile of virulence associated MAP genes under various stress conditions.Virulence associated MAP gene definitions ... It is interesting to note that leuD gene itself is annotated as a virulence associated gene in VFDB. Some of the virulence ... It is interesting to note that leuD gene itself is annotated as a virulence associated gene in VFDB. Some of the virulence ... pone-0037884-g005: Expression profile of virulence associated MAP genes under various stress conditions.Virulence associated ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3366959_pone.0037884.g005&req=4
*  2-for-1 bacterial virulence factor revealed | EurekAlert! Science News
Drugs that hobble the production of virulence factors, small molecules that help bacteria to establish an infection in a host, ... In Infectious Diseases he describes recent work on a target virulence factor. ... One class of virulence factors common to many pathogens is siderophores, small molecules whose job is to seek out iron in the ... Virulence factors allow bacteria to evade the human immune system, to infect tissues and cells and to establish a foothold ...
  https://www.eurekalert.org/pub_releases/2016-01/wuis-tbv011516.php
*  Twin-arginine translocation in Yersinia : the substrates and their role in virulence
Twin-arginine translocation in Yersinia: the substrates and their role in virulence. Avican, Ummehan Umeå University, Faculty ... However, the role of other protein secretion and/or translocation systems in virulence of Yersinia species is not well known. ... Tat has been shown to be required for the virulence of Yersinia pseudotuberculosis, and we recently showed that the system is ... In this study, we wanted to address the role of the Tat substrates in in vivo virulence. Therefore, 22 genes encoding potential ...
  http://www.diva-portal.org/smash/record.jsf?pid=diva2:1048949
*  Imperfect vaccines and the evolution of pathogen virulence
... Download. Read.pdf (179.2Kb) ... In contrast, infection-blocking vaccines induce no such effects, and can even select for lower virulence. These findings have ... The subsequent evolution leads to higher levels of intrinsic virulence and hence to more severe disease in unvaccinated ... populations.We studied the potential impact of different types of imperfect vaccines on the evolution of pathogen virulence ( ...
  https://www.era.lib.ed.ac.uk/handle/1842/711
*  Mouse monoclonal to CD40 - Role of adrenergic receptors in human coronary vasomotion
The relative virulence of the colony types was WR > PH > SM as measured by CFU in rat lungs after intratracheal […] ... strains display variability in their capsular polysaccharide cell morphology karyotype and virulence but the BAPTA relationship ...
  http://researchreportone.com/?tag=mouse-monoclonal-to-cd40
*  pathogen virulence
The hypothesis of the paper is that virulence and rate of infection would necessarily be highly correlated as virulence ... pathogen virulence. Jamie BNYB000 at MUSICB.MCGILL.CA Mon Nov 20 12:24:59 EST 1995 *Previous message: Amphipathic Helices ... Ideally I would like to measure virulence in time from infection to death of host and transmission in time from infection of ...
  http://www.bio.net/bionet/mm/microbio/1995-November/003829.html
*  The role of virulence factors in Candida albicans pathogenicity - E-JURNAL
In this review, some virulence factors were discussed. Indeed, there were factors that may be considered as putative virulence ... The role of virulence factors in Candida albicans pathogenicity Ilmu Kesehatan Jp Kedokteran gg 2016 Edit ... However, there were fndings that showed the possibility of putative virulence factors work on the transition of commensally to ...
  http://www.e-jurnal.com/2016/11/the-role-of-virulence-factors-in.html
*  Metabolic pathways and virulence factors of Y. pestis i | Open-i
Metabolic pathways and virulence factors of Y. pestis induced in the flea and the mammalian host. Metabolic functions and ... Coregulation of host-adapted metabolism and virulence by pathogenic yersiniae. Heroven AK, Dersch P - Front Cell Infect ... Coregulation of host-adapted metabolism and virulence by pathogenic yersiniae. Heroven AK, Dersch P - Front Cell Infect ... Figure 2: Metabolic pathways and virulence factors of Y. pestis induced in the flea and the mammalian host. Metabolic functions ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4202721_fcimb-04-00146-g0002&req=4
*  Gram negative bacteria | JAMS
In this talk I will discuss some specific ecological conditions that promote the long-term maintenance of virulence ... Recent theory predicts that evolution towards increased virulence can be reversed if less virulent social 'cheats' exploit ... Experiments reveal that the fitness costs of decreased virulence are eliminated in mixed infections, whereas less virulent ... I will demonstrate that for the bacterium Pseudomonas syringae, major virulence polymorphisms are maintained at unexpectedly ...
  http://jams.org.au/taxonomy/term/589
*  CASCADE study suggests HIV has increased in virulence and transmissibility
... News / 2017 / 2016 / 2015 / 2014 / 2013 / 2012 / ... Home , News , 2014 , CASCADE study suggests HIV has increased in virulence and transmissibility ... The term used to describe a virus' ability to cause illness is virulence. If someone is infected with a more virulent form of ... In order to track changes in HIV virulence over time, the researchers looked at specific points in HIV infection before the ...
  http://www.ctu.mrc.ac.uk/news/2014/cascade_15122014
*  Bacteria in the gut are controlling what we eat | BIOS and other things
According to this hypothesis, it has been shown that bacterial virulence proteins activate pain receptors. It has been shown ... The detection of sugars and other nutrients regulates virulence and growth of various microbes. These directly injure the ... may be due to the expression of bacterial virulence genes and perception of pain by the host. This is because the production of ...
  https://abordonseng.wordpress.com/2014/10/12/bacteria-in-the-gut-are-controlling-what-we-eat/
*  British Library EThOS: Investigation of virulence gene regulation in Streptococcus pneumoniae
The factors that determine the virulence of S. pneumoniae are very complex but a key aspect of the organism's disease causing ... The requirement for different virulence gene regulators varied according to the murine model of infection used. Two of the ... In this study two main approaches were taken to investigate virulence gene expression in S. pneumoniae. Firstly, the ... Secondly, the requirement for and the role of virulence gene regulators identified by Signature Tagged Mutagenesis were ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.410462
*  Transmission bottlenecks as determinants of virulence in rapidly evolving pathogens
We argue that the patterns of accumulation of deleterious mutation may explain differing levels of virulence in vertically and ... Transmission bottlenecks can dramatically affect the evolution of virulence in rapidly evolving pathogens such as RNA viruses. ... we use analytical and simulation methods to demonstrate that severe bottlenecks are likely to drive down the virulence of a ...
  https://digital.lib.washington.edu/researchworks/handle/1773/2006
*  Growth rate, transmission mode and virulence in human pathogens | Department of Biology
... and virulence. Overall, our results emphasize how virulence can be influenced by mechanistic life-history details, especially ... Classic theory for the evolution of virulence is based on a trade-off between pathogen growth, transmission and host survival, ... The harm that pathogens cause to hosts during infection, termed virulence, varies across species from negligible to a high ... we found the opposite correlation to the expected positive correlation between pathogen growth rate and virulence. We found ...
  https://www.biology.lu.se/charlie-cornwallis/publication/75041dc7-4967-4478-af83-0eb395177b86
*  Molecular Mechanisms of Bacterial Virulence - Clarence I. Kado; Jorge H. Crosa; | Foyles Bookstore
... regulation of virulence genes and signal transduction, and pathogen of host-defence mechanisms. ... This volume brings together studies on the differences and profound similarities in the molecular mechanism of virulence ... This volume brings together studies on the differences and profound similarities in the molecular mechanism of virulence ... regulation of virulence genes and signal transduction, and pathogen of host-defence mechanisms. ...
  http://www.foyles.co.uk/witem/medical-veterinary/molecular-mechanisms-of-bacterial,clarence-i-kado-jorge-h-crosa-9780792319016
*  virulence - Wiktionary
Retrieved from "https://en.wiktionary.org/w/index.php?title=virulence&oldid=48323635" ...
  https://en.wiktionary.org/wiki/virulence
*  Virulence factor | microbiology | Britannica.com
... produce a variety of so-called virulence factors that permit them to evade the defense mechanisms of the host and thus cause ... Other articles where Virulence factor is discussed: necrotizing fasciitis: … ... produce a variety of so-called virulence factors that permit them to evade the defense mechanisms of the host and thus cause ...
  https://www.britannica.com/science/virulence-factor
*  Histoplasma Virulence and Host Responses
... Mircea Radu Mihu1 and Joshua Daniel Nosanchuk2 ... the current knowledge regarding the multiple facets of the dynamic host-pathogen relationship in the context of the virulence ...
  https://www.hindawi.com/journals/ijmicro/2012/268123/abs/
*  Virulence in Context | Science
Thank you for your interest in spreading the word about Science.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
  http://science.sciencemag.org/content/306/5699/1097.6
*  Virulence factor BrkB (IPR017039) | InterPro | EMBL-EBI
Virulence factor BrkB (IPR017039). Short name: Virul_fac_BrkB Family relationships *Virulence factor BrkB (IPR017039) *Inner ...
  http://www.ebi.ac.uk/interpro/entry/IPR017039
*  Proline Promotes Virulence | Science Signaling
Osmotic stress also contributes to the regulation of virulence factors, contributing to the detection of a new host, and L- ... identified proline as a molecular trigger in insect extracts that stimulated the production of small molecules with virulence ... Proton motive force (PMF), a consequence of metabolic activity, also contributes to the regulation of bacterial virulence, and ... suggesting that L-proline or its metabolites differentially regulate the production of virulence factors. ...
  http://stke.sciencemag.org/content/3/106/ec31