viral interference Archives - The Crux : The Crux
Tag: viral interference. Viral Infections Might Be Our Best Hope Against AIDS & Other Confounding Diseases. By Laura Kasman , ... This phenomenon, called viral interference, has been seen in the lab for a while, but it was generally thought to be an ... MORE ABOUT: common cold, flu, hepatitis B, hepatitis D, HIV, rhinovirus, viral interference, virology, virus ... The advent of PCR rewrote our understanding of viral interactions, as it did for many areas of biology. We learned that almost ...http://blogs.discovermagazine.com/crux/tag/viral-interference/
Viral Interference and Persistence in Mosquito-Borne Flaviviruses
... Juan Santiago Salas-Benito1,2 and Mónica De Nova-Ocampo1,2 ... Juan Santiago Salas-Benito and Mónica De Nova-Ocampo, "Viral Interference and Persistence in Mosquito-Borne Flaviviruses," ...https://www.hindawi.com/journals/jir/2015/873404/cta/
Viruses | Free Full-Text | Viral Interference with Functions of the Cellular Receptor Tyrosine Phosphatase CD45
Here we report what is known about the interaction of viral proteins with CD45. Moreover, we debate putative interactions of ... Viral Interference with Functions of the Cellular Receptor Tyrosine Phosphatase CD45. Nadine Thiel. ... "Viral Interference with Functions of the Cellular Receptor Tyrosine Phosphatase CD45." Viruses 7, no. 3: 1540-1557. ... Thiel N, Zischke J, Elbasani E, Kay-Fedorov P, Messerle M. Viral Interference with Functions of the Cellular Receptor Tyrosine ...http://www.mdpi.com/1999-4915/7/3/1540
Interferon - used, first, blood, body, produced, Viral Interference, New Interest
Viral Interference Early in his studies of influenza (flu) at the World Influenza Centre at the National Institute for Medical ... interested in the viral interference phenomenon, first described in 1935. It was observed that an RNA virus in a cell inhibits ... Interferon is a protein produced by animals in response to viral infections. It is a defensive mechanism by the body to prevent ... It is now known that interferon is produced within hours of a viral invasion and that most living things, including plants, can ...http://www.discoveriesinmedicine.com/Hu-Mor/Interferon.html
RNA interference viral suppressor and RNA - Stock Image F009/6224 - Science Photo Library
RNA interference, or RNA silencing, has developed in plants as a defence against viruses. However, some viruses have developed ... RNA interference viral suppressor and RNA. Molecular model of the p19 protein (yellow) from a Tombusvirus, suppressing a double ... Caption: RNA interference viral suppressor and RNA. Molecular model of the p19 protein (yellow) from a Tombusvirus, suppressing ... rna interference, rna silencing, short interfering rna, si rna, sirna, small interfering rna, strand, structure, suppressing, ...http://www.sciencephoto.com/media/597505/view
Viral vector-mediated RNA interference.
Abstract RNA interference (RNAi) is a powerful gene silencing mechanism that if properly harnessed has the potential to ... Viral vector systems, based on adeno-associated viruses and lentiviruses, are ideally suited to mediate RNAi because they can ... Abstract RNA interference (RNAi) is a powerful gene silencing mechanism that if properly harnessed has the potential to ... There are now many examples of the use of viral vector-mediated RNAi to inhibit gene expression in animal models of disease, ...https://www.omicsonline.org/references/viral-vectormediated-rna-interference-1183560.html
British Library EThOS: Viral vector-mediated RNA interference in the retina
RNA interference (RNAi) is a highly conserved post-transcriptional gene silencing process triggered by double-stranded RNA ( ... The aim of this thesis is to evaluate the efficacy of viral vector-mediated RNAi in the retina using recombinant adeno- ... A detailed assessment of the utility and extend of RNAi in the retina using different viral vectors and hairpin designs is ...http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564940
Research programme: RNA interference-based viral therapeutics - MDRNA - AdisInsight
formerly Nastech Pharmaceutical) was developing small interfering RNA (siRNA) therapeutics targeting viral respiratory ... Research programme: RNA interference-based viral therapeutics - MDRNA Alternative Names: G 00101; MDR-03030; MDRNA Dicer ... Mechanism of Action RNA interference * Orphan Drug Status Orphan designation is assigned by a regulatory body to encourage ...https://adisinsight.springer.com/drugs/800024381?error=cookies_not_supported&code=dfa2922b-54ab-4552-a44b-9541cb8cc22c
Interference with the production of infectious viral particles and bimodal inhibition of replication are broadly conserved...
Interference with the production of infectious viral particles and bimodal inhibition of replication are broadly conserved ... suggesting that viral receptors add an additional layer of complexity in the IFITMs-HIV interplay. Lastly, we show that the ... The swapping of genetic elements between resistant and susceptible viruses allowed us to point to specificities in the viral ...https://www.physiciansweekly.com/interference-with-the-production-of-infectious-viral-particles-and-bimodal-inhibition-of-replication-are-broadly-conserved-antiviral-properties-of-ifitms/
Abbott Laboratories | Vanderbilt News | Vanderbilt University
RSV-HRV viral interference. May. 15, 2017-RSV infection reduces the risk of infection with human rhinovirus, which could have ... implications for vaccine development and prevention strategies for viral respiratory tract infections in infants. ...https://news.vanderbilt.edu/tag/abbott-laboratories/
Viruses | Free Full-Text | HCV Innate Immune Responses
These in vitro findings will have to be confirmed in clinical trials investigating the molecular mechanisms of HCV interference ... This striking ability to evade the powerful innate immune system results from viral interference occurring at several levels of ... viral interference interferon; MAVS; Toll-like receptors; Jak-STAT; HCV; viral interference ... This striking ability to evade the powerful innate immune system results from viral interference occurring at several levels of ...http://www.mdpi.com/1999-4915/1/3/1073
Immune evasion by pathogens of bovine respiratory disease complex | Animal Health Research Reviews | Cambridge Core
Yewdell, JW and Hill, AB (2002). Viral interference with antigen presentation. Nature Immunology 3: 1019-1025. ... Viral Immunology 12: 323-334.. Brown, GB, Bolin, SR, Frank, DE and Roth, JA (1991). Defective function of leukocytes from ... Viral Immunology 10: 21-34.. Negrete-Abascal, E, Tenorio, VR and de la Garza, M (1999). Secretion of proteases from Pasteurella ... Wittum, TE, Grotelueschen, DM, Brock, KV, Kvasnicka, W, Floyd, WJ, Kelling, CL and Odde, KG (2001). Persistent bovine viral ...https://www.cambridge.org/core/journals/animal-health-research-reviews/article/immune-evasion-by-pathogens-of-bovine-respiratory-disease-complex/927F29BB207D24D834BD9207CF904102
Specific Targeting of the EBV Lytic Phase Protein BNLF2a to the Transporter Associated with Antigen Processing Results in...
Viral interference with antigen presentation. Nat. Immunol. 3: 1019-1025. OpenUrlCrossRefPubMed ... 80 viral proteins and the production of viral particles that can amplify the latent pool or mediate viral transmission to ... Interestingly, the viral protein appears stable in cells in which only the TAP1 subunit is present (Fig. 5⇑), suggesting that a ... Viral modulation of antigen presentation: manipulation of cellular targets in the ER and beyond. Immunol. Rev. 207: 126-144. ...http://www.jimmunol.org/content/182/4/2313.long
Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10 ...
Viral interference and interferon. Br. Med. Bull. 15:185-188.. OpenUrlFREE Full Text ... Type I IFNs, including IFN-α, IFN-β, and IFN-ω, are ubiquitious cytokines originally shown to inhibit viral infection ( ... and viral (Müller et al., 1994) and bacterial infection (O'Connell et al., 2004; Mancuso et al., 2007). Their functions in ...http://jem.rupress.org/content/early/2010/01/18/jem.20091959
Frontiers | Genetic Transformation and Genomic Resources for Next-Generation Precise Genome Engineering in Vegetable Crops |...
Ali, Z., Abulfaraj, A., Idris, A., Ali, S., Tashkandi, M., and Mahfouz, M. M. (2015). CRISPR/Cas9-mediated viral interference ... have been cloned in place of endogenous viral genes encoding coat and movement proteins in a modified Bean Yellow Dwarf Virus ( ...https://www.frontiersin.org/articles/10.3389/fpls.2017.00241/full
Determinants of Responses to Oral Vaccines in Developing Countries - Abstract - Annales Nestlé (English ed.) 2008, Vol. 66, No....
1. The poor seroconversion rates and the absence of viral interference. Am J Epidemiol 1972;96:263-269. External Resources * ... Katz M, Plotkin SA: Oral polio immunization of the newborn infant; a possible method for overcoming interference by ingested ... Related issues including breastfeeding, interference from maternal placental antibodies, intestinal parasitic infections, ...https://www.karger.com/Article/Abstract/129624
An Overview of the Immune Evasion Strategies Adopted by Different Viruses with Special Reference to Classical Swine Fever Virus...
There is also evidence of viral interference with interferons. Interferons were discovered because of their ability to protect ... evasion by integration of viral genome into host cell genome (induction of prophage in case of retro viral infection) and ... 2005Persistence of bovine viral diarrhea virus is determined by a cellular cofactor of a viral autoprotease. J. Virol., ... The key role of both type I (α and β) and type II (γ) IFNs as one of the first anti-viral defense mechanisms is indicated by ...https://www.intechopen.com/books/viral-replication/an-overview-of-the-immune-evasion-strategies-adopted-by-different-viruses-with-special-reference-to-/
Peter K. Vogt - Wikipedia
Vogt, PK; Ishizaki R (1966). "Patterns of viral interference in the avian leukosis and sarcoma complex". Virology. 30 (3): 368- ... At the beginning of his scientific career, Vogt studied mechanisms of retroviral cell entry and the role of viral surface ... He defined related groups of viral surface proteins and their corresponding receptors on the cell surface. During his time in ... His research focuses on retroviruses and viral and cellular oncogenes. Vogt received his undergraduate education in biology at ...https://en.wikipedia.org/wiki/Peter_K._Vogt
A Knockdown Punch To The Brain | The New York Academy Of Sciences
Viral-Mediated RNA Interference in Neuroscience Research. Devidze, N., J. A. Mong, A. M. Jasnow et al. 2005. Sex and estrogenic ... Viral-Mediated RNA Interference in Neuroscience Research*Effects of LIS1 RNAi on Neural Stem Cell Polarization, Division, and ... Delivering RNA interference to the mammalian brain. Curr. Gene Ther. 5: 399-410.. Thakker, D. R., D. Hoyer & J. F. Cryan. 2006 ... DNA-directed RNA Interference. The Promega Corporation's web site on this subject provides background on this topic.. Gene ...https://www.nyas.org/ebriefings/a-knockdown-punch-to-the-brain/
Comprehensive Virology (ebook) by Heinz Fraenkel-Conrat | 9781468435634
Defective Virus and Viral Interference.- 6.1. Defective Virus.- 6.2. Interference by Defective Virus.- 6.3. Other Forms of ... The Viral Genome.- 3.4. The Viral Capsid.- 3.5. Viral Enzymes.- 4. Replication.- 4.1. Adsorption and Penetration.- 4.2. Site of ... Synthesis of Viral Nucleic Acids.- 4.4. Synthesis of Viral Proteins.- 4.5. Mutants and Defective Particles.- 4.6. Effect of ... Viral RNA.- 4.5. Viral Protein.- 5. The Virion.- 5.1. Purification.- 5.2. Morphology and Structure.- 5.3. Sedimentation.- 5.4. ...https://www.ebooks.com/1304704/comprehensive-virology/fraenkel-conrat-heinz/
Recombinant DNA Approaches to Feline Leukemia Virus Immunization | SpringerLink
Sarma, P.S., and T. Log (1971) Viral interference in feline leukemia-sarcoma complex. Virology 44:352-358.PubMedCrossRefGoogle ... Norrby, E. (1983) Viral vaccines: The use of currently available products and future developments. Archives of Virology 75:163- ... Experience with retrovi ruses and other viral vaccines in animal models is thus of great importance in guiding the way toward ...https://link.springer.com/chapter/10.1007/978-1-4684-5110-8_18
Interferon - Wikipedia
... the discovery was a result of their studies of viral interference. Viral interference refers to the inhibition of virus growth ... Binding of molecules uniquely found in microbes-viral glycoproteins, viral RNA, bacterial endotoxin (lipopolysaccharide), ... They also limit viral spread by increasing p53 activity, which kills virus-infected cells by promoting apoptosis. The effect of ... RNA interference technology tools such as siRNA or vector-based reagents can either silence or stimulate interferon pathways. ...https://en.wikipedia.org/wiki/Interferon
Feline leukemia virus - Wikipedia
Subgroups are defined on the basis of viral interference and in vitro host range. The differences are due to polymorphism in ... In an infected cell, gp70 is thought to block viral receptors, so preventing further infection by the same subgroup. Cats ... recurring bacterial and viral illnesses, anemia, diarrhea and jaundice. Asymptomatic carriers will show no signs of disease, ...https://en.wikipedia.org/wiki/Feline_leukemia_virus
Viruses | Free Full-Text | Neutralizing Antibodies and Pathogenesis of Hepatitis C Virus Infection | HTML
This review summarizes recent concepts of the role of neutralizing antibodies in viral clearance and protection, and highlights ... and to chronic viral infection. The development of novel model systems to study HCV entry and neutralization has allowed a ... Furthermore, viral evasion from host neutralizing antibodies has been revealed to be an important contributor in leading both ... consequences of viral escape from neutralizing antibodies in the pathogenesis of HCV infection. ...http://www.mdpi.com/1999-4915/4/10/2016/htm
Viruses | Free Full-Text | Perinatal Lamb Model of Respiratory Syncytial Virus (RSV) Infection
Hiding Lipid Presentation: Viral Interference with CD1d-Restricted Invariant Natural Killer T (iNKT) Cell Activation ...http://mdpi.com/1999-4915/4/10/2359/xml