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*  Paraganglioma - Paragangliomas Summary Report | CureHunter
Vesicular Monoamine Transport Proteins (Vesicular Monoamine Transporter)IBA 06/01/2010 - "6-18F-fluoro-L-dihydroxyphenylalanine ... 08/01/2006 - "The aims of this study were to investigate the quantitative expression of vesicular monoamine transporters (VMAT ... 04/01/2011 - "Expression of somatostatin receptors, dopamine D₂ receptors, noradrenaline transporters, and vesicular monoamine ... or vesicular monoamine transporter 2 to predict paragangliomas, showing a prediction error of 0%. ". ...
  http://www.curehunter.com/public/keywordSummaryD010235-Paraganglioma-Paragangliomas.do
*  3,4-Methylenedioxymethamphetamine ('Ecstasy')-induced serotonin neurotoxicity: Studies in animals<...
... toxic effects on brain 5-HT neurons in animals and present new data indicating that levels of the type 2 vesicular monoamine ... toxic effects on brain 5-HT neurons in animals and present new data indicating that levels of the type 2 vesicular monoamine ... toxic effects on brain 5-HT neurons in animals and present new data indicating that levels of the type 2 vesicular monoamine ... toxic effects on brain 5-HT neurons in animals and present new data indicating that levels of the type 2 vesicular monoamine ...
  https://jhu.pure.elsevier.com/en/publications/34-methylenedioxymethamphetamine-ecstasy-induced-serotonin-neurot-7
*  Vesicular monoamine transporter - Wikipedia
The vesicular monoamine transporter (VMAT) is a transport protein integrated into the membrane of synaptic vesicles of ... Accessed 20 April 2013] Vesicular Monoamine Transport Proteins at the US National Library of Medicine Medical Subject Headings ... VMAT uses the same transport mechanism for all types of monoamines. VMATs transport monoamines from the cytosol into high- ... 2006). "Regulation of vesicular monoamine and glutamate transporters by vesicle-associated trimeric G-proteins: new jobs for ...
  https://en.wikipedia.org/wiki/Vesicular_monoamine_transporter
*  The pharmacological profile of the vesicular monoamine transporter resembles that of multidrug transporters. - PubMed - NCBI
Vesicular Biogenic Amine Transport Proteins. *Vesicular Monoamine Transport Proteins. Substances. *ATP Binding Cassette ... The pharmacological profile of the vesicular monoamine transporter resembles that of multidrug transporters.. Yelin R1, ... These findings induced us to test whether compounds that are typically transported by MDR interact also with vesicular ... interact specifically with vesicular monoamine transporters. Verapamil, a calcium channel blocker, is also a competitive ...
  https://www.ncbi.nlm.nih.gov/pubmed/8543051?dopt=Abstract
*  Genetic Association Analysis of 300 Genes Identifies a Risk Haplotype in SLC18A2 for Post-traumatic Stress Disorder in Two...
SLC18A2 is involved in transporting monoamines to synaptic vesicles and has been implicated in a number of neuropsychiatric ... vesicular monoamine transporter 2). A haplotype analysis of 9 SNPs in SLC18A2, including rs363276, identified a risk haplotype ... Brain dopamine-serotonin vesicular transport disease presenting as a severe infantile hypotonic parkinsonian disorder. *Jessie ...
  https://www.semanticscholar.org/paper/Genetic-Association-Analysis-of-300-Genes-a-Risk-in-Solovieff-Roberts/07ab72c2838399bd87c504fa8ff663d3719b7277
*  Functionally important carboxyls in a bacterial homologue of the vesicular monoamine transporter (VMAT). - PubMed - NCBI
Vesicular Monoamine Transport Proteins/chemistry*. *Vesicular Monoamine Transport Proteins/genetics. *Vesicular Monoamine ... Also shown for reference (★) are liposomes reconstituted with no protein (mock). B, rates of transport in the presence of ... Functionally important carboxyls in a bacterial homologue of the vesicular monoamine transporter (VMAT).. Yaffe D1, Vergara- ... C, inhibition of MPP+ transport by nigericin. D, inhibition of MPP+ transport by 10 μm of known substrates (ethidium, ...
  https://www.ncbi.nlm.nih.gov/pubmed/25336661
*  Effects of dopaminergic drug treatments on in vivo radioligand binding to brain vesicular monoamine transporters. | DIAL.pr -...
Vesicular Biogenic Amine Transport Proteins ; Vesicular Monoamine Transport Proteins ; Biological Transport ; Brain ; COS Cells ... Animals ; Membrane Transport Proteins ; Mice ; Mice, Inbred Strains ; Neuropeptides ; Radioligand Assay ; Rats ; Rats, Sprague- ... Effects of dopaminergic drug treatments on in vivo radioligand binding to brain vesicular monoamine transporters. Primary tabs ... Home» Effects of dopaminergic drug treatments on in vivo radioligand binding to brain vesicular monoamine transporters. ...
  https://dial.uclouvain.be/pr/boreal/object/boreal:123339
*  NEUROLOGICAL - David A Steenblock Do Inc
Vesicular Monoamine Transport Proteins (Vesicular Monoamine Transporter): 4 results : IBA. *MAP Kinase Kinase Kinase 5: 4 ... Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase): 13 results : IBA. *TATA-Box Binding Protein (TATA-Binding Protein): 13 ... Monoamine Oxidase (MAO): 2 outcomes 5 studies in 89 results : IBA. *Staphylococcal Protein A (A, Protein): 2 outcomes 5 studies ... S100 Proteins (S 100 Protein): 1 study in 5 results : IBA. *Methylene Blue (Methylthioninium Chloride): 1 study in 5 results : ...
  https://personalized-regenerative-medicine.com/neurological/
*  Ephedrine Neurotoxicity
Intracellular DA depletion using the DA , synthesis inhibitor alpha-methyl-p-tyrosine or the vesicular monoamine , transport ... protein damage, and cell death. As in earlier studies, AMPH rapidly , redistributed vesicular DA to the cytoplasm, where it ... Despite these AMPH-induced changes, neither protein oxidation nor cell death , was observed until 1 and 4 days, respectively. ... recombinant glutathione-S-transferase fusion protein and delineated the , catalytic domain of the enzyme as the region spanning ...
  http://www.bio.net/bionet/mm/neur-sci/2003-May/054567.html
*  San Diego Source > News > Neurocrine Biosciences granted two...
Nasdaq: NBIX) has announced that two more patents have been granted related to the company's proprietary Vesicular Monoamine ... a protein concentrated in the human brain that is primarily responsible for re-packaging and transporting monoamines, like ... Nasdaq: NBIX) has announced that two more patents have been granted related to the company's proprietary Vesicular Monoamine ...
  http://www.sddt.com/News/article.cfm?SourceCode=20130124tqb&_t=Neurocrine+Biosciences+granted+two+patents
*  DiVA - Search result
Vesicular monoamine transporter 1 (VMAT1) is an integral protein in the membrane of secretory vesicles of neuroendocrine and ... We have developed a new two-step targeting strategy to transport (125)I into cancer-cell nuclei using PEG-stabilized tumour- ... Identification and characterization of a novel splicing variant of vesicular monoamine transporter 12005In: Journal of ... The combination of in situ PLA and flow cytometry provided a statistically powerful way of analyzing protein-protein ...
  http://uu.diva-portal.org/smash/resultList.jsf?af=%5B%5D&aq=%5B%5B%7B%22personId%22%3A%22larsgedd%22%7D%5D%5D&aqe=%5B%5D&aq2=%5B%5B%5D%5D&language=en&query=
*  WO2003000236A1 - Particles with improved solubilization capacity - Google Patents
Vesicular acetycholine transport, (VACht ), Vesicular monoamine transporter (VMAT2), Villin, Vimentin, Vinculin, VIP ( ... Protein 4.1 M ascites, Protein G, Protein Kinase C, Pseudomonas mallei, PTH, Pulmonary Surfactant Associated Proteins, ... Examples of membrane proteins include, in addition to receptor proteins, such proteins as proteinase A, amyloglucosidase, ... Nucleolar Protein N038, Nuclear Protein xNopp 180, Nucleoplasm, Protein AND- 1 , Nucleolus Organizing Region (NOR), Nucleolin, ...
  https://patents.google.com/patent/WO2003000236A1/en
*  Reuptake inhibitor - Wikipedia
... is an irreversible inhibitor of the vesicular monoamine transporter 2 (VMAT2), and is a prototypical example of a vesicular ... With vesicular transport blocked, neurotransmitter stores quickly become depleted. Reserpine (Serpasil) ... which exerts its effects by causing conformational changes in the transporter protein and thereby modulating the affinity of ... triethylcholine Vesicular acetylcholine transporter (VAChT) inhibitor - vesamicol Vesicular monoamine transporter (VMAT) ...
  https://en.wikipedia.org/wiki/Reuptake_inhibitor
*  Drug Transport in Living Systems - CHEMICAL BIOLOGY
... - reflects the multidimensional character of chemical biology, focusing in ... The vesicular monoamine transporters (VMATs) from the SLC18 family provide another example of polyspecific proteins with a very ... Membrane transport proteins recognize these drug molecules and in an energy-dependent manner transport them across the plasma ... Transport proteins. With MDTs the only detailed structural evidence is provided by AcrB. The recent structure of AcrB in the ...
  http://schoolbag.info/chemistry/chemical_biology/34.html
*  Enhancing Vesicular Packaging May Offer New Therapeutic Target for Parkinson's
Vesicular monoamine transporter 2 (VMAT2) is a protein that packages dopamine and other monoamine neurotransmitters into ... The VMAT2-overexpressing mice exhibited a two-fold increase in vesicular transport, which increased dopamine release 84 percent ... Increased vesicular monoamine transporter enhances dopamine release and opposes Parkinson disease-related neurodegeneration in ... Enhancing Vesicular Packaging May Offer New Therapeutic Target for Parkinson's Enhancing Vesicular Packaging May Offer New ...
  https://www.niehs.nih.gov/research/supported/sep/2014/enhancing_vesicular_packaging/
*  History of catecholamine research - Wikipedia
... and the vesicular monoamine transporter (VMAT) with two isoforms. Transporters and intracellular enzymes such as monoamine ... With the advent of molecular genetics, the three transport mechanisms have been traced to the proteins and their genes since ... I. Demonstration of monoamines in the cell bodies of brain stem neurons". Acta Physiologica Scandinavica. 62, suppl. 247: 1-55 ... It was later named monoamine oxidase. This seemed to clarify the fate of the catecholamines in the body, but in 1956 Blaschko ...
  https://en.wikipedia.org/wiki/History_of_catecholamine_research
*  Vesicular monoamine transporter 2 - Wikipedia
... is a protein that in humans is encoded by the SLC18A2 gene. VMAT2 is an integral membrane protein that transports monoamines- ... Little KY, Krolewski DM, Zhang L, Cassin BJ (January 2003). "Loss of striatal vesicular monoamine transporter protein (VMAT2) ... by simultaneously reversing the direction of transport through the primary plasma membrane transport proteins for monoamines (i ... Play media The vesicular monoamine transporter 2 (VMAT2) also known as solute carrier family 18 member 2 (SLC18A2) ...
  https://en.wikipedia.org/wiki/Vesicular_monoamine_transporter_2
*  SLC18A3 Gene - GeneCards | VACHT Protein | VACHT Antibody
Protein Coding), Solute Carrier Family 18 Member A3, including: function, proteins, disorders, pathways, orthologs, and ... This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine ... of ATP-dependent transporters that also includes vesicular monoamine transporters (VMAT) 1 and VMAT2. VAChT is found in the ... Protein details for SLC18A3 Gene (UniProtKB/Swiss-Prot). Protein Symbol:. Q16572-VACHT_HUMAN. Recommended name:. Vesicular ...
  https://www.genecards.org/cgi-bin/carddisp.pl?gene=SLC18A3
*  Immunomodulatory Effects Mediated by Dopamine
K. M. Ashe, W.-L. Chiu, A. M. Khalifa et al., "Vesicular monoamine transporter-1 (VMAT-1) mRNA and immunoreactive proteins in ... S. M. Parsons, "Transport mechanisms in acetylcholine and monoamine storage," The FASEB Journal, vol. 14, no. 15, pp. 2423-2434 ... G. W. Miller, J. D. Erickson, J. T. Perez et al., "Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein ... 3.4.1. DRs Are G Protein-Coupled Receptors (GPCR). DRs belong to a superfamily of membrane proteins, called the G protein- ...
  https://www.hindawi.com/journals/jir/2016/3160486/
*  Membrane transport protein - wikidoc
Membrane transport protein: neurotransmitter transporters. Vesicular. Vesicular monoamine (VMAT1, VMAT2) - Vesicular ... Acyl carrier protein - Adaptor protein - Cholesterylester transfer protein - F-box protein - GTP-binding protein - Latent TGF- ... Active transport. Transport proteins are also used in active transport, which by definition does require an energy input. ... Transport proteins are integral membrane proteins; that is they exist within and span the membrane across which they transport ...
  http://es.wikidoc.org/index.php/Membrane_transport_protein
*  Catecholamines up - Wikipedia
... and Vesicular Monoamine Transporter (VMAT) in Drosophila melanogaster. Catsup plays a significant role in zinc ion ... transmembrane transport, and the mutations in Catsup gene can lead to abnormal accumulation of membrane proteins, such as Notch ... and Vesicular Monoamine Transporter (VMAT) enzyme activity. Various molecular polymorphisms of Catsup are associated with ... Catsup encoded protein is composed of seven predicted transmembrane domains and Catsup co-localizes with enzymes TH and VMAT to ...
  https://en.wikipedia.org/wiki/Catecholamines_up
*  Histamine - DrugBank
Monoamine transmembrane transporter activity. Specific Function. Involved in the ATP-dependent vesicular transport of biogenic ... Protein binding. Not Available. Metabolism. Primarily hepatic. Histamine is rapidly metabolized by methylation and oxidation. ... Transports one sodium ion with one molecule of carnitine. Also transports organic cat.... Gene Name. SLC22A5. Uniprot ID. ... Gonzalez AM, Walther D, Pazos A, Uhl GR: Synaptic vesicular monoamine transporter expression: distribution and pharmacologic ...
  https://www.drugbank.ca/drugs/DB05381
*  Gonzalo Torres
Proteins interacting with monoamine transporters: current state and future challenges.. Sager JJ, Torres GE.. Biochemistry. ... The molecular chaperone Hsc70 interacts with the vesicular monoamine transporter-2. .. Requena DF, Parra LA, Baust TB, Quiroz M ... A biochemical and functional protein complex involving dopamine synthesis and transport into synaptic vesicles. .. Cartier EA, ... Monoamine Transporters: the role of oligomerization in transporter function, how transporter proteins are targeted to specific ...
  http://www.neurobio.pitt.edu/faculty/torres.htm
*  Characterization of Bacterial Drug Antiporters Homologous to Mammalian Neurotransmitter Transporters | Journal of Bacteriology
The vesicular monoamine transporter (VMAT) catalyzes the accumulation of neurotransmitters in organelles in exchange for two ... The result supports the contention that transport catalyzed by the three proteins is driven by proton electrochemical gradient. ... Charged residues in transmembrane domains II and XI of a vesicular monoamine transporter form a charge pair that promotes high ... The pharmacological profile of the vesicular monoamine transporter resembles that of multidrug transporters. FEBS Lett. 377:201 ...
  https://jb.asm.org/content/187/21/7518?ijkey=c39e9aac1ab9efcfd892be3c950485b8042eba96&keytype2=tf_ipsecsha
*  Vesicular monoamine transporter 1 - Wikipedia
SLC18A1 is an isoform of the vesicular monoamine transporter. The idea that there must be specific transport proteins ... This transport is facilitated via proton gradient generated by the protein proton ATPase. The inward transport of the monoamine ... Vesicular monoamine transporter 1 (VMAT1) also known as chromaffin granule amine transporter (CGAT) or solute carrier family 18 ... The active transport of monoamines from the cytosol into storage vesicles operates against a large (>105) concentration ...
  https://en.wikipedia.org/wiki/Vesicular_monoamine_transporter_1