Effect of Double Dose of Alpha 1-antitrypsin Augmentation Therapy on Lung Inflammation. - Full Text View - ClinicalTrials.gov
This is a pilot study to test the effect of double dose augmentation therapy with Zemaira (CSL Behring) on lung inflammation, compared with standard doses of 60 mg/kg/week.. Our hypothesis is that some patients with AATD receiving augmentation therapy at the standard dose of 60 mg/kg/week continue to have a significant lung inflammation that may lead to detrimental clinical consequences. This inflammation can be further reduced with higher AAT dosing.. The study will enroll 20 subjects with AATD and COPD already receiving augmentation therapy with any brand at standard doses for at least a month. For inclusion and exclusion criteria see below.. Protocol:. The study will take place over approximately 12 weeks: a month receiving Zemaira at standard dose (60 mg/kg/week), a month at double dose (120 mg/kg/week) and a month at standard dose (60 mg/kg/week). The infusions at standard doses will be done at home and infusions with higher doses will be provided at the study site.. the study involves ...
Trial to Study the Effects of Supplementary Omega-3 on Serum C-Reactive Protein Levels - Full Text View - ClinicalTrials.gov
To study the anti-inflammatory effects of marine omega-3 fatty acids, also known as n-3 polyunsaturated fatty acids (PUFA), we propose a randomized, double-blinded, prospective, single-center trial to examine the effect of supplementary n-3 PUFA on serum high sensitivity (hs) CRP levels.. Inclusion Criteria Age , 18 hs CRP ,3mg/L and ,10 mg/L. Exclusion Criteria. Active infection Systemic Inflammatory Disease Autoimmune disorders Systemic Lupus Erythematosus (SLE) Rheumatoid Arthritis (RA) Systemic Sclerosis (Scleroderma) Sjögren's Syndrome Behçet's Syndrome. The Vasculitis Syndromes Including:. Wegener's granulomatosis Temporal arteritis (Giant cell arteritis) Takayasu's arteritis Henoch-Schönlein purpura Predominantly cutaneous vasculitis (hypersensitivity vasculitis) Sarcoidosis Amyloidosis Currently on warfarin Cr , 2.0 Fish Allergy Pregnancy or unwillingness to use some form of birth control in women of child-bearing age during the 8 ...
Renal participation of myeloperoxidase in antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis - The...
Renal participation of myeloperoxidase in antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis Journal Articles Refereed ...
DMOZ - Health: Conditions and Diseases: Immune Disorders: Auto-Immune: Microscopic Polyangiitis
Microscopic polyangiitis (MPA), previously called hypersensitivity angiitis, is a systemic necrotizing vasculitis that involves many organ systems including the skin, joints, kidneys, and lungs.
Comprehensive annual financial report of the University of North Carolina at Chapel Hill :: State Publications
the university of north carolina at chapel hill Comprehensive Annual Financial Report 2007 fiscal year ended June 30, 2007 , Chapel Hill, North Carolina A Constituent Institution of the University of North Carolina System and a Component Unit of the State of North Carolina the university of north carolina at chapel hill Comprehensive Annual Financial Report 2007 A Constituent Institution of the University of North Carolina System and a Component Unit of the State of North Carolina Prepared by the Cont rol ler 's Of f ice 07 June 30, 2007 , Chapel Hi l l , North Carolina 2 T h e U n i v e r s i t y of Nor t h C a rol i n a at C h a p e l H i l l 2 0 0 7 Co m p r e h e n s i v e a n n u a l f i n a n c i a l r e p o r t 3 5 Introductory Section 6 Message from the Chancellor 9 Letter of Transmittal 14 Progress and Major Initiatives 22 Board of Trustees 22 Chancellor's Cabinet 23 Organization Chart 25 Financial Section 26 Report of the Independent Auditor 28 Management's Discussion and Analysis ...
Antineutrophil cytoplasmic antibody definition | Drugs.com
Definition of antineutrophil cytoplasmic antibody. Provided by Stedman's medical dictionary and Drugs.com. Includes medical terms and definitions.
Catalog :: State Publications
S C H O O L O F I N F O R M A T I O N A N D L I B R A RY S C I E N C E VtàtÄÉz ECCJ@ECCK THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL Published by the University of North Carolina at Chapel Hill Send all undeliverable copies and changes of address to: The School of Information and Library Science The University of North Carolina at Chapel Hill CB# 3360, 100 Manning Hall Chapel Hill, NC 27599-3360 This document was published by the School of Information and Library Science. SILS The School of Information and Library Science The University of North Carolina at Chapel Hill CB# 3360, 100 Manning Hall Chapel Hill, NC 27599-3360 919/962-8366; fax 919/962-8071 e-mail: email@example.com http://sils.unc.edu THE GRADUATE SCHOOL CB# 4010, 200 Bynum Hall The University of North Carolina at Chapel Hill 919/966-2611; e-mail: firstname.lastname@example.org http://gradschool.unc.edu STUDENT LOANS AND FEDERAL ASSISTANCE Office of Scholarships and Student Aid The University of North Carolina at Chapel Hill CB# 2300, 300 ...
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T Cell Costimulatory and Coinhibitory Pathways in Vascular Inflammatory Diseases
A broad array of evidence indicates that T lymphocytes make significant contributions to vascular inflammation in the setting of atherosclerotic disease, hypertension, autoimmune vasculitis, and other disorders. Experimental data show that costimulatory and coinhibitory pathways involving molecules of the B7-CD28 and TNF-TNFR families regulate T cell responses that promote vascular disease. Antigen presenting cells (APCs) display both peptide-major histocompatibility complex antigen and costimulators or coinhibitors to T cells. Two major types of APCs, dendritic cells (DCs) and macrophages, are present in significant numbers in the walls of arteries affected by atherosclerosis and arteritis, and some DCs are present in normal arteries. Costimulatory and coinhibitory molecules expressed by these vascular APCs can contribute to the activation or inhibition of effector T cells within the arterial wall. Vascular DCs may also be involved in transport of antigens to secondary lymphoid organs, ...
Comprehensive annual financial report of the University of North Carolina at Chapel Hill :: State Publications
A CONSTITUENT INSTITUTION OF THE UNIVERSITY OF NORTH CAROLINA SYSTEM AND A COMPONENT U N I T O F T H E S TAT E O F NORT H C A RO L I N A 2004COMPREHENSIVE A N N U A L F I N A N C I A L R E P O R T FISCAL YEAR ENDED JUNE 30, 2004 · CHAPEL HILL, NORTH CAROLINA A CONSTITUENT INSTITUTION OF THE UNIVERSITY OF NORTH CAROLINA SYSTEM AND A COMPONENT U N I T O F T H E S TAT E O F NORT H C A RO L I N A 2004COMPREHENSIVE A N N U A L F I N A N C I A L R E P O R T FISCAL YEAR ENDED JUNE 30, 2004 · CHAPEL HILL, NORTH CAROLINA OFFICE OF THE VICE CHANCELLOR FOR FINANCE AND ADMINISTRATION 2 T H E U N I V E R S I T Y O F N O R T H C A R O L I N A A T C H A P E L H I L L Table of Contents 3 INTRODUCTORY SECTION 4 Message from the Chancellor 7 Letter of Transmittal 12 Progress and Major Initiatives 21 Board of Trustees 21 Chancellor's Cabinet 22 Organization Chart 23 FINANCIAL SECTION 24 Report of the Independent Auditor 26 Management's Discussion and Analysis BASIC FINANCIAL STATEMENTS 40 Statement of Net Assets ...
Pigmented purpuric dermatoses (capillaritis)
The pigmented purpuric dermatoses (PPDs), also known as capillaritis, purpura simplex, and inflammatory purpura without vasculitis, are a group of chronic, benign, cutaneous eruptions characterized by the presence of petechiae, purpura, and increased
Renal Fellow Network: Interesting Case of Adult Henoch-Schonlein Purpura
All opinions expressed on the website are those of the respective authors and not of their employer. Information provided here is for medical education only. It is not intended as and does not substitute for medical advice. If you are a patient, please see your doctor for evaluation. The appearance of external hyperlinks to other websites does not constitute endorsement. We do not verify, endorse or take responsibility for the accuracy, currency, completeness or quality of the content contained in these sites. There is no real life patient data on this website. The Renal Fellow Network does not profit from any of the material on this website. No advertisements are accepted. The Renal Fellow Network is not funded by any agency or company. Any information collected by our website, such as email addresses, will never be passed on to any third party, unless required by law. The Renal Fellow Network is moderated occasionally and posteriorly. Moderators are volunteers. Internet users posting comments ...
Cryoglobulinaemia dictionary definition | cryoglobulinaemia defined
cryoglobulinaemia definition: Noun (countable and uncountable, plural cryoglobulinaemias) 1. Alternative spelling of cryoglobulinemia....
News letter of the University of North Carolina at Chapel Hill Department of History :: State Publications
THE NEWSLETTER Department of History • The University of North Carolina Number 53 Chapel Hill, North Carolina Autumn 2004 GREETINGS FROM THE CHAIR Historians know that nothing ever stays the same and that all human institutions are forever changing across time. We have seen this familiar historical process unfolding in Hamil-ton Hall over the past year as the UNC History Department passed through its own modest version of regime change and the continuing evolution of our faculty and staff. Our De-partment Chair for the last five and a half years, Peter Cocla-nis, accepted a new administrative position (Associate Provost for International Affairs) and moved to South Building at the beginning of January. Peter led the department with excep-tional efficiency, good sense, and vision, so his departure from the chair's position marked an important change and challenge for the life of our community. It also led to my appointment as the new chair-a post that I have assumed with apprecia-tion for the ...
Scarring a necessary evil to prevent further damage after he... ( CHAPEL HILL N.C. After a heart atta...)
...CHAPEL HILL N.C. After a heart attack the portions of the heart dam...In a study appearing online November 15 2011 in the EMBO Journal... We now know that scarring is a good thing because it prevents a prec...Regeneration happens naturally in lower organisms like zebrafish the ...,Scarring,a,necessary,evil,to,prevent,further,damage,after,heart,attack,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
Chapelboro - Chapel Hill and Carrboro News, Photos, and Events
Local news, sports, lifestyle, and opinions. Covering Chapel Hill, Carrboro, Hillsborough, Chatham County, UNC, the Tar Heels, and more.
UNC researchers find clue to stopping breast-cancer ... ( CHAPEL HILL If scientists knew exac...)
Health, ...CHAPEL HILL If scientists knew exactly what a breast cancer cell need...Carol Otey Ph.D. and UNC colleagues reduced the ability of breast can...They also found higher levels of palladin in four invasive breast canc... This study shows that palladin may play an important role in the meta...,UNC,researchers,find,clue,to,stopping,breast-cancer,metastasis,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Cryoglobulins and Cryoprecipitation - Alliance for Cryoglobulinemia
Cryoglobulins: Understanding the pieces, the pipe and the reason to Stay Warm. Cryoglobulins: As the name implies and science tells us, exposure to cold causes cryoglobulin precipitation, which thickens our blood.
Publications Jan 2017 - Aug 2017 | Intelligent Systems Program | University of Pittsburgh
The Effect Of PiZ Genotype And Augmentation Therapy On Bronchoalveolar Lavage (BAL) And Peripheral Blood Mononuclear Cell (PBMC) Transcriptomes In Alpha-1 Antitrypsin Deficiency [Link] ...
Dr. Frances Collichio, MD - Chapel Hill, NC - Oncology & Internal Medicine | Healthgrades.com
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Dr. Nora Franceschini, MD - Chapel Hill, NC - Nephrology | Healthgrades.com
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Dr. Palak Parikh, MD - Chapel Hill, NC - Nephrology | Healthgrades.com
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Overview of the management of vasculitis in adults
The vasculitides are defined by the presence of leukocytes in the vessel wall with reactive damage to mural structures. In general, affected vessels vary in size, type, and location in association with the specific vasculitic disorder. These conditio
K-JK) START OF TAPE 1, SIDE A LUCY LEWIS FEBRUARY 19, 2001 LILI LAI: Today is February 19; I'm interviewing Ms. Lucy Lewis. Were you born in Chapel Hill, here? LUCY LEWIS: No, I was ...
Indications / Contraindication
Contact Us UNC Division of Transplant 4024 Burnett Womack Building CB #7211 Chapel Hill NC 27599-7211 Phone 919-966-8008 Fax 919-966-6308 Español: 919-966-3464 ...