RCSB PDB - 2MR7: apo structure of the Peptidyl Carrier Protein Domain 7 of the teicoplanin producing Non-ribosomal peptide...
The biosynthesis of the glycopeptide antibiotics, of which teicoplanin and vancomycin are representative members, relies on the ...
PDB-101: Molecule of the Month: Vancomycin
The antibiotic vancomycin blocks the construction of bacterial cell walls. ... The antibiotic vancomycin blocks the construction of bacterial cell walls.. This structure includes vancomycin (blue) and a ... As shown here in PDB entry 1fvm , vancomycin binds tightly to this D-alanine-D-alanine peptide, blocking the ability to form ... Vancomycin is effective for blocking formation of this type of cell wall and is currently used as a last resort antibiotic for ...