*  Intercept Pharma's Liver Drug Wins Accelerated Approval by the FDA | PharmaLive
... in combination with ursodeoxycholic acid (UDCA) in adults with an inadequate response to UDCA, or as monotherapy in adults ... Bile Acid Binding Resins. Bile acid binding resins such as cholestyramine, colestipol or colesevelam absorb and reduce bile ... FDA Grants Accelerated Approval to Ocaliva™ (Obeticholic Acid) for the Treatment of Patients with PBC ... If taking bile acid binding resins, take Ocaliva at least 4 hours before or 4 hours after (or at as great an interval as ...
  http://www.pharmalive.com/intercept-pharmas-liver-drug-wins-accelerated-approval-by-the-fda/
*  Fenofibrate in Combination With Ursodeoxycholic Acid (UDCA) in Primary Biliary Cirrhosis - Full Text View - ClinicalTrials.gov
Fenofibrate in Combination With Ursodeoxycholic Acid (UDCA) in Primary Biliary Cirrhosis. This study has been withdrawn prior ... The purpose of this study is to determine if the combination of ursodeoxycholic acid (UDCA) and fenofibrate is more effective ... Ursodeoxycholic Acid. Hypolipidemic Agents. Antimetabolites. Molecular Mechanisms of Pharmacological Action. Lipid Regulating ... Randomized Controlled Study of Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis. ...
  https://clinicaltrials.gov/ct2/show/NCT01141296
*  Effect of ursodeoxycholic acid on the kinetics of cholic acid and chenodeoxycholic acid in patients with primary sclerosing...
If you are a society or association member and require assistance with obtaining online access instructions please contact our Journal Customer Services team ...
  http://onlinelibrary.wiley.com/doi/10.1002/hep.1840170614/pdf
*  A dose-up of ursodeoxycholic acid decreases transaminases in hepatitis C patients
Changes in bile acid composition in patients with primary biliary cirrhosis induced by ursodeoxycholic acid administration. ... 5. Poupon R, Serfaty L. Ursodeoxycholic acid in chronic hepatitis C. Gut. 2007;56:1652-1653. [PMC free article] [PubMed] ... Effects of ursodeoxycholic acid on survival in patients with primary biliary cirrhosis. Gastroenterology. 1996;110:1515-1518. [ ... Ursodeoxycholic acid for primary sclerosing cholangitis. J Hepatol. 1990;11:120-123. [PubMed] ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2695895/
*  Phase 3 Study of Bezafibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis - Full Text View -...
Ursodeoxycholic acid (UDCA) administered orally at the daily dose of 13-15 mg/kg is currently the only drug approved for the ... Phase 3 Study of Bezafibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis (BEZURSO). This study has ... Bezafibrate 400 mg or placebo will be daily administered in combination with ursodeoxycholic acid (UDCA) 13-15 mg/kg/d for 24 ... Ursodeoxycholic Acid. Bezafibrate. Cholagogues and Choleretics. Gastrointestinal Agents. Hypolipidemic Agents. Antimetabolites ...
  https://clinicaltrials.gov/ct2/show/NCT01654731
*  LIVER FIBROSIS REGRESSES BETTER WITH PEGINTERFERON ALPHA AND URSODEOXYCHOLIC ACID TREATMENT THAN SPONTANEOUS RECOVERY
LIVER FIBROSIS REGRESSES BETTER WITH PEGINTERFERON ALPHA AND URSODEOXYCHOLIC ACID TREATMENT THAN SPONTANEOUS RECOVERY. ... which has better antiviral activity and ursodeoxycholic acid (UDCA). Liver fibrosis was established on 60 male Sprague Dawley ...
  http://www.natap.org/2003/EASL/day17.htm
*  Ursodeoxycholic acid inhibits pro-inflammatory repertoires, IL-1β and nitric oxide in rat microglia | SpringerLink
... hydrophilic bile acid in widespread clinical use mainly for acute and chronic liver disease. Recently, treatment with UDCA in ... Ursodeoxycholic acid (UDCA) is a non-toxic, hydrophilic bile acid in widespread clinical use mainly for acute and chronic liver ... Hirano, F., Tanaka, H., Makino, Y., Okamoto, K., and Makino, I., Effects of ursodeoxycholic acid and chenodeoxycholic acid on ... Rodrigues, C. M. P., Ma, X., Kren, B. T., and Streer, C. J., A novel role for ursodeoxycholic acid in inhibiting apotosis by ...
  https://link.springer.com/article/10.1007%2FBF02994760
*  Ursodeoxycholic Acid And Cholestasis Of Pregnancy - Full Text View - ClinicalTrials.gov
Experimental: Ursodeoxycholic acid obstetrical monitoring plus active drug. Drug: Ursodeoxycholic Acid 300 mg capsules 20 mg/kg ... Ursodeoxycholic Acid And Cholestasis Of Pregnancy (CERTO). This study has been withdrawn prior to enrollment. ... Bile Acids [ Time Frame: from enrolment until delivery ]. *Fetal movement count [ Time Frame: from enrolment until delivery ]. ...
  https://clinicaltrials.gov/ct2/show/NCT01226823?recr=Open&cond=%22Pregnancy%22&rank=19
*  Ursodiol 300mg buy - How Can I Order Urso Without RX - 留学益友问答
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*  Ursodeoxycholic acid and cholesterol induce enterohepatic cycling of " by Sanchez N. Mendez, M A. Brink et al.
Oral administration of ursodeoxycholic acid (UDCA) and cholesterol causes bile salt malabsorption; the former by competition ... METHODS: Male inbred C57L/J mice and Sprague-Dawley rats were fed low doses of UDCA, chenodeoxycholic acid (CDCA), or ... Dietary cholesterol and bile acids, particularly UDCA, increased cecal bile salt levels, unconjugated bilirubin and ... for and the latter by down-regulation of ileal bile acid transporters. Because ileectomy in rats induces enterohepatic cycling ...
  https://mouseion.jax.org/stfb1990_1999/1114/
*  A large-scale, multicentre, double-blind trial of ursodeoxycholic acid in patients with chronic hepatitis C | Gut
We assessed oral ursodeoxycholic acid (UDCA) on serum biomarkers as a possible treatment for interferon nonresponders. ... A large-scale, multicentre, double-blind trial of ursodeoxycholic acid in patients with chronic hepatitis C ... A large-scale, multicentre, double-blind trial of ursodeoxycholic acid in patients with chronic hepatitis C ...
  http://gut.bmj.com/content/early/2007/08/30/gut.2007.120956
*  Effects of ursodeoxycholic acid on systemic, renal and forearm haemodynamics and sodium homoeostasis in cirrhotic patients with...
Hydrophobic bile acids, which have vasodilatory actions, may be involved. Ursodeoxycholic acid, a hydrophilic bile acid, could ... Ursodeoxycholic acid caused a significant reduction in sodium excretion in both groups (P, 0.05). This, in the post-TIPS ... The effects of ursodeoxycholic acid on systemic, renal and forearm haemodynamics, liver function and renal sodium handling were ... Effects of ursodeoxycholic acid on systemic, renal and forearm haemodynamics and sodium homoeostasis in cirrhotic patients with ...
  http://www.clinsci.org/content/96/5/467
*  Liver protective effect of ursodeoxycholic acid includes regulation of ADAM17 activity. | Sigma-Aldrich
Ursodeoxycholic acid (UDCA) is used to treat primary biliary cirrhosis, intrahepatic cholestasis, and other cholestatic ... Liver protective effect of ursodeoxycholic acid includes regulation of ADAM17 activity.. [Halka Buryova, Karel Chalupsky, Olga ...
  https://www.sigmaaldrich.com/catalog/papers/24172289
*  From the inside out
In their paper entitled "Ursodeoxycholic acid binds ileal bile acid binding protein," to be published in the April issue of the ... A small amount of ursodeoxycholic acid, also known as UDCA or ursodiol, has been a component in Chinese traditional medicine ... UDCA increases the binding of major human bile acids; this decreases the number of free bile acids in cytosol, reducing stress ... and UDCA was shown to bind cooperatively with a major human bile acid bound to the other binding site just as two bile acids ...
  https://www.asbmb.org/asbmbtoday/asbmbtoday_article.aspx?id=16455
*  Ursodeoxycholic Acid (sodium salt)
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*  Ursodeoxycholic Acid in Bariatric Surgery - Full Text View - ClinicalTrials.gov
Active Comparator: Ursodeoxycholic acid Oral ursodeoxycholic acid 20 mg/kg/day in three weeks ... Effects of Ursodeoxycholic Acid on Hepatobiliary Detoxification/Elimination Mechanisms and Hepatic Fatty Acid/Triglyceride ... Ursodeoxycholic Acid in Bariatric Surgery. The safety and scientific validity of this study is the responsibility of the study ... Serum from days 1 and 21 will be analyzed for routine liver tests, bile acids, a complete lipid profile including FA and in ...
  https://clinicaltrials.gov/ct2/show/NCT01548079?term=Acid+Lipase+Disease&rank=17
*  ATC - A05AA02 - Ursodeoxycholic Acid - Drugs-about.com
Ursodeoxycholic Acid. The Anatomical Therapeutic Chemical (ATC) classification system from Drugs-about.com includes all drugs ... A05AA - Bile acid preparations*A05AA02 - Ursodeoxycholic Acid *Ursodeoxycholic Acid ATC Classification , Pharmaceutical Drugs ...
  http://drugs-about.com/atc/a05aa02.html
*  Potentiation of Photodynamic Therapy by Ursodeoxycholic Acid | Cancer Research
Ursodeoxycholic acid (UDCA) protects cells from the apoptotic effects of hydrophobic bile acids and some other cytotoxic agents ... Rodrigues C. M., Fan G., Wong P. Y., Kren B. T., Steer C. J. Ursodeoxycholic acid may inhibit deoxycholic acid-induced ... Ljubuncie P., Fuhrman B., Oiknine J., Aviram M., Bomzon A. Effect of deoxycholic acid and ursodeoxycholic acid on lipid ... Potentiation of Photodynamic Therapy by Ursodeoxycholic Acid. David Kessel, Joseph A. Caruso and John J. Reiners Jr. ...
  http://cancerres.aacrjournals.org/content/60/24/6985
*  Ursodeoxycholic Acid as Treatment for Polycystic Liver Disease - Full Text View - ClinicalTrials.gov
Ursodeoxycholic Acid as Treatment for Polycystic Liver Disease (CURSOR). The safety and scientific validity of this study is ... Ursodeoxycholic acid in advanced polycystic liver disease: A phase 2 multicenter randomized controlled trial. J Hepatol. 2016 ... Experimental: Ursodeoxycholic Acid The intervention group will receive 15-20mg/kg/day UDCA for 24 weeks ... Drug: Ursodeoxycholic Acid The intervention group will receive 15-20mg/kg/day UDCA for 24 weeks ...
  https://clinicaltrials.gov/ct2/show/NCT02021110?cond=%22Kidney+Diseases%2C+Cystic%22&rank=14
*  Ursodeoxycholic acid and cholestasis of pregnancy - Pregnancy Blog
Ursodeoxycholic acid and cholestasis of pregnancy. Means ursodeoxycholic acid and cholestasis of pregnancy toxic substances ... Another ursodeoxycholic acid and cholestasis of pregnancy point is to enjoy cold water, because it speeds up the metabolism and ... My ursodeoxycholic acid and cholestasis of pregnancy is on Ursoeeoxycholic and I can't keep her full. Like many more ... In ursodeoxycholic acid and cholestasis of pregnancy the rectum connects with other organs, these organs need to be repaired. ...
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*  Chenodeoxycholic Acid and Ursodeoxycholic Acid | Springer for Research & Development
Tint, G. S., Salen, G., and Shefer, S.: Effect of ursodeoxycholic acid and chenodeoxycholic acid on cholesterol and bile acid ... Ursodeoxycholic acid versus chenodeoxycholic acid. Comparison of their effects on bile acid and bile lipid composition in ... Fedorowski, T., Salen, G., Tint, G. S., and Mosbach, E.: Transformation of chenodeoxycholic acid and ursodeoxycholic acid by ... Maxwell R.A., Eckhardt S.B. (1990) Chenodeoxycholic Acid and Ursodeoxycholic Acid. In: Drug Discovery. Humana Press, Totowa, NJ ...
  https://rd.springer.com/chapter/10.1007/978-1-4612-0469-5_28
*  Ursodeoxycholic acid - Wikipedia
While some bile acids are known to be colon tumor promoters (e.g. deoxycholic acid), others such as ursodeoxycholic acid are ... Ursodeoxycholic acid information at MedlinePlus Ursodeoxycholic acid in the British National Formulary. ... "Bile acids deoxycholic acid and ursodeoxycholic acid differentially regulate human β-defensin-1 and -2 secretion by colonic ... Primary and secondary bile acids help the body digest fats. Ursodeoxycholic acid helps regulate cholesterol by reducing the ...
  https://en.wikipedia.org/wiki/Ursodeoxycholic_acid
*  Ursodeoxycholic Acid Attenuates Endoplasmic Reticulum Stress-Related Retinal Pericyte Loss in Streptozotocin-Induced Diabetic...
S. J. Woo, J. H. Kim, and H. G. Yu, "Ursodeoxycholic acid and tauroursodeoxycholic acid suppress choroidal neovascularization ... Ursodeoxycholic Acid Attenuates Endoplasmic Reticulum Stress-Related Retinal Pericyte Loss in Streptozotocin-Induced Diabetic ... A.-L. Cao, L. Wang, X. Chen et al., "Ursodeoxycholic acid and 4-phenylbutyrate prevent endoplasmic reticulum stress-induced ... J. M. Gaspar, A. Martins, R. Cruz, C. M. P. Rodrigues, A. F. Ambrósio, and A. R. Santiago, "Tauroursodeoxycholic acid protects ...
  https://www.hindawi.com/journals/jdr/2017/1763292/ref/
*  GastroHep News Story
Ursodeoxycholic acid combined with bezafibrate for itching. 07 February 2018 Change in microbiome in gastritis vs gastric ...
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