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*  Hydrogen peroxide induces overexpression of angiotensin-converting enzyme in human umbilical vein endothelial cells. | Sigma...
Hydrogen peroxide induces overexpression of angiotensin-converting enzyme in human umbilical vein endothelial cells.. [Xiaoqin ... and the mechanisms underlying ACE regulation in human umbilical vein endothelial cells (HUVECs). We used Tetrazolium bromide ( ...
  https://www.sigmaaldrich.com/catalog/papers/23153326
*  Umbilical vein, light micrograph - Stock Image C023/5951 - Science Photo Library
Light micrograph of a section through a human umbilical cord showing the umbilical vein. The vein consists of an inner lumen ( ... Around the vein is the jelly-like mucous connective tissue (pale pink) known as Wharton's jelly. The umbilical cord is the ... Most of the vein consists of several concentric layers of smooth muscle. ... Caption: Umbilical vein. Light micrograph of a section through a human umbilical cord showing the umbilical vein. The vein ...
  http://www.sciencephoto.com/media/644174/view
*  Umbilical Vein Catheterization: Background, Indications, Contraindications
The umbilical vein remains patent and viable for cannulation until approximately 1 week after birth. ... Umbilical vein catheterization may be a life-saving procedure in neonates who require vascular access and resuscitation. ... Umbilical vein catheterization. Technique for umbilical vein dilation and insertion of catheter. ... encoded search term (Umbilical%20Vein%20Catheterization) and Umbilical Vein Catheterization What to Read Next on Medscape. ...
  https://emedicine.medscape.com/article/80469-overview
*  Fetal umbilical vein deviation in congenital diaphragmatic hernia.
Objectives Deviation of the intra-abdominal umbilical vein has been described as a marker of congenital diaphragmatic hernia ( ... "umbilical vein ratio." The accuracy of the umbilical vein ratio for predicting the presence and side of the hernia and for ... the midhepatic portion of the umbilical vein was identified, and the distance between the lateral edge of the vein and the ... Results All but 1 of the cases with right-sided hernias had an umbilical vein ratio above the normal range, and all had liver ...
  http://www.biomedsearch.com/nih/Fetal-umbilical-vein-deviation-in/23341382.html
*  Phytoestrogen α-Zearalanol Attenuates Homocysteine-Induced Apoptosis in Human Umbilical Vein Endothelial Cells
... Teng Liu,1 Dan- ... Results showed that homocysteine (500 μmol/L, 24 h) induced the apoptosis of human umbilical vein endothelial cells (HUVECs) ...
  https://www.hindawi.com/journals/bmri/2013/813450/abs/
*  Umbilical vein catheter | definition of umbilical vein catheter by Medical dictionary
What is umbilical vein catheter? Meaning of umbilical vein catheter medical term. What does umbilical vein catheter mean? ... Looking for online definition of umbilical vein catheter in the Medical Dictionary? umbilical vein catheter explanation free. ... Related to umbilical vein catheter: Umbilical artery catheter. umbilical vein catheter. Neonatology A support line for drawing ... See Umbilical artery catheter. umbilical vein catheter. A catheter placed in the umbilical vein of an infant to facilitate ...
  https://medical-dictionary.thefreedictionary.com/umbilical+vein+catheter
*  Umbilical vein | definition of umbilical vein by Medical dictionary
... umbilical vein explanation free. What is umbilical vein? Meaning of umbilical vein medical term. What does umbilical vein mean? ... Looking for online definition of umbilical vein in the Medical Dictionary? ... Related to umbilical vein: right umbilical vein left um·bil·i·cal vein. the vein that returns the blood from the placenta to ... umbilical vein. one of a pair of veins which return oxygenated blood from the placenta through the umbilical cord to the ductus ...
  https://medical-dictionary.thefreedictionary.com/umbilical+vein
*  Insulin-Increased L-Arginine Transport Requires A2A Adenosine Receptors Activation in Human Umbilical Vein Endothelium
... in human umbilical vein endothelial cells (HUVECs). Insulin increases hCAT-1 activity and expression in HUVECs, and A2AAR ... Umbilical veins Is the Subject Area "Umbilical veins" applicable to this article? Yes. No. ...
  http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0041705
*  Umbilical vein - Wikipedia
A newborn baby has a patent umbilical vein for at least a week after birth. This umbilical vein may be catheterised for ready ... The blood pressure inside the umbilical vein is approximately 20 mmHg. The unpaired umbilical vein carries oxygen and nutrient ... The umbilical vein is a vein present during fetal development that carries oxygenated blood from the placenta into the growing ... Closure of the umbilical vein usually occurs after the umbilical arteries have closed. This prolongs the communication between ...
  https://en.wikipedia.org/wiki/Umbilical_vein
*  Long-Zhi Decoction Medicated Serum Promotes Angiogenesis in Human Umbilical Vein Endothelial Cells Based on Autophagy
HUVECs, human umbilical vein endothelial cells; LZDMS, long-zhi decoction medicated serum. (a/b) Cells were treated with or ... HUVECs, human umbilical vein endothelial cells; LZDMS, long-zhi decoction medicated serum. The control group (a), HUVECs that ... HUVECs, human umbilical vein endothelial cells; LZDMS, long-zhi decoction medicated serum. (a) Cells were exposed to the ... HUVECs, human umbilical vein endothelial cells; LZDMS, long-zhi decoction medicated serum. (a, b) Control group: HUVECs scratch ...
  https://www.hindawi.com/journals/ecam/2018/6857398/
*  3- O-Acetyloleanolic acid exhibits anti-angiogenic effects and induces apoptosis in human umbilical vein endothelial cells |...
... migration and tube formation of human umbilical vein endothelial cells (HUVECs) in a... ... 3-O-Acetyloleanolic acid exhibits anti-angiogenic effects and induces apoptosis in human umbilical vein endothelial cells. ... 3-O-Acetyloleanolic acid Apoptosis Human umbilical vein endothelial cell Matrigel plug assay ... migration and tube formation of human umbilical vein endothelial cells (HUVECs) in a dose-dependent manner. HUVECs. The induced ...
  https://link.springer.com/article/10.1007%2Fs10529-013-1266-7
*  Frontiers | The Influence of C-Ions and X-rays on Human Umbilical Vein Endothelial Cells | Oncology
We thus chose human umbilical vein endothelial cells (HUVEC) as a model system to examine the effect of low and high linear ... We thus chose human umbilical vein endothelial cells (HUVEC) as a model system to examine the effect of low and high linear ... The Influence of C-Ions and X-rays on Human Umbilical Vein Endothelial Cells. Alexander Helm1*, Ryonfa Lee1†, Marco Durante1,2 ... Radiosensitivity and sublethal damage repair in human umbilical cord vein endothelial cells. Int J Radiat Oncol Biol Phys (1987 ...
  https://www.frontiersin.org/articles/10.3389/fonc.2016.00005/full
*  Characterization of the Polymorphonuclear Leukocyte-Induced Vasoconstriction in Isolated Human Umbilical Veins | Journal of...
Preparation of umbilical vein segments.. Human umbilical cords were obtained from Danbury Hospital within 12 h of delivery and ... human umbilical vein segments. IL-1β. interleukin 1 beta. γ-IFN. interferon-gamma. TNF-α. tumor necrosis factoralpha. BIRM-270 ... human umbilical vein endothelial cells. PECAM-1. platelet-endothelial cell adhesion molecule 1, ICAM-1, intercellular adhesion ... Effect of PMNs on isolated human umbilical vein.. Both unactivated and fMLP-activated human PMNs produced a robust and dose- ...
  http://jpet.aspetjournals.org/content/287/2/640
*  Propranolol induces apoptosis of human umbilical vein endothelial cells through downregulation of CD147 - Xie - 2013 - British...
Propranolol induces apoptosis of human umbilical vein endothelial cells through downregulation of CD147. ... Propranolol induces apoptosis of human umbilical vein endothelial cells through downregulation of CD147. British Journal of ...
  http://onlinelibrary.wiley.com/doi/10.1111/bjd.12193/references
*  Variability among human umbilical vein endothelial cultures. - Semantic Scholar
Variability among human umbilical vein endothelial cultures.' by Cornelius A. Watson et al. ... ICD-10-PCS : Umbilical Venous Catheters and Umbilical Arterial Catheters Umbilical Arterial Catheters. Oct 17, 2017 ... Role of Rutin on Nitric Oxide Synthesis in Human Umbilical Vein Endothelial Cells. *Azizah Ugusman, Zaiton Zakaria, Kien Hui ... Immortalization of swine umbilical vein endothelial cells (SUVECs) with the simian virus 40 large-T antigen.. *Marcin Chrusciel ...
  https://www.semanticscholar.org/paper/Variability-among-human-umbilical-vein-endothelial-Watson-Camera-Benson/65aa03e6f25a4e52894c2036bb1347ca087f67cb
*  Human umbilical vein endothelial cell - Wikipedia
Play media Human umbilical vein endothelial cells (HUVECs) are cells derived from the endothelium of veins from the umbilical ... Human umbilical vein endothelial cells at the US National Library of Medicine Medical Subject Headings (MeSH) Primary Umbilical ... Park HJ, Zhang Y, Georgescu SP, Johnson KL, Kong D, Galper JB (2006). "Human umbilical vein endothelial cells and human dermal ... Like human umbilical artery endothelial cells they exhibit a cobblestone phenotype when lining vessel walls. ...
  https://en.wikipedia.org/wiki/Human_umbilical_vein_endothelial_cell
*  Further Pharmacological Evidence of Nuclear Factor-κB Pathway Involvement in Bradykinin B1 Receptor-Sensitized Responses in...
human umbilical vein. IL. interleukin. NF-κB. nuclear factor-κB. PDTC. pyrrolidine-dithiocarbamate. Bay 11-7082. 3-(4- ... In isolated human umbilical vein (HUV), the BK B1receptor-mediated contractile response develops from an initial null level and ... In isolated human umbilical vein (HUV), a spontaneous BK B1 receptor up-regulation and sensitization process has been ... 2000b) Retinoids inhibit bradykinin B1-receptor sensitized responses in human umbilical vein. Eur J Pharmacol 407:313-316. ...
  http://jpet.aspetjournals.org/content/301/3/975
*  GW24-e3984 Effects of tetramethylpyrazine on human umbilical vein endothelial cells exposed to constant or intermittent high...
Objectives To explore the influence of constant or intermittent high glucose on human umbilical vein endothelial cells (HUVECs ... GW24-e3984 Effects of tetramethylpyrazine on human umbilical vein endothelial cells exposed to constant or intermittent high ... GW24-e3984 Effects of tetramethylpyrazine on human umbilical vein endothelial cells exposed to constant or intermittent high ...
  http://heart.bmj.com/content/99/Suppl_3/A104.1
*  Relationship between erythropoietin and nitric oxide in the contraction of rat renal arcuate arteries and human umbilical vein...
Relationship between erythropoietin and nitric oxide in the contraction of rat renal arcuate arteries and human umbilical vein ... Relationship between erythropoietin and nitric oxide in the contraction of rat renal arcuate arteries and human umbilical vein ... Relationship between erythropoietin and nitric oxide in the contraction of rat renal arcuate arteries and human umbilical vein ... Relationship between erythropoietin and nitric oxide in the contraction of rat renal arcuate arteries and human umbilical vein ...
  http://www.clinsci.org/content/97/4/413
*  Bee products prevent VEGF-induced angiogenesis in human umbilical vein endothelial cells | BMC Complementary and Alternative...
The aim of this study was to investigate the anti-angiogenic effects of bee products using human umbilical vein endothelial ... The aim of this study was to investigate the anti-angiogenic effects of bee products using human umbilical vein endothelial ... Bee products prevent VEGF-induced angiogenesis in human umbilical vein endothelial cells. ... using human umbilical vein endothelial cells (HUVECs) as a model in vitro system. ...
  https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/1472-6882-9-45

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*  HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS: A NEW SOURCE AND POTENTIAL TARGET FOR CORTICOTROPIN-RELEASING FACTOR. | IRIS Università...
Corticotropin-releasing factor (CRF) plays a key role in the modulation of fetal-placental unit function during human pregnancy. CRF has a potent vasoactive action on fetal-placental circulation. As products secreted from endothelial cells affect vascular wall reactivity, we investigated whether cultured human umbilical vein endothelial cells (HUVEC) may represent a source and a target for CRF. With RT-PCR we showed that HUVEC express CRF and CRF receptor type 2 messenger ribonucleic acids. Cultured HUVEC also released CRF peptide in a time-dependent way, and the CRF release was differently regulated by various molecules. Dexamethasone decreased CRF release, whereas progesterone and 17beta-estradiol markedly increased it. Forskolin and PGF2alpha were potent stimulators of CRF release from HUVEC. Among the peptides, CRF secretion was stimulated by interleukin-1beta and by endothelin-1. Our study shows for the first time that HUVEC express CRF messenger ribonucleic acid and peptide as well as ...
  https://usiena-air.unisi.it/handle/11365/6510
*  AID 73598 - Inhibition of human umbilical vein endothelial cell (HUVEC) adhesion to fibronectin at 300 uM (No inhibition) -...
BioAssay record AID 73598 submitted by ChEMBL: Inhibition of human umbilical vein endothelial cell (HUVEC) adhesion to fibronectin at 300 uM (No inhibition).
  https://pubchem.ncbi.nlm.nih.gov/bioassay/73598
*  LOX-DB - LipOXygenases DataBase - Literature
13-S-Hydroxyoctadecadienoic acid (13-S-HODE), the product of 15-lipoxygenase (15-LOX) metabolism of linoleic acid, enhances cellular mitogenic responses to certain growth factors. Other observations have questioned whether 13-S-HODE has tumorigenic effects. Our study evaluated the hypothesis that 15-LOX-1 is overexpressed in colon cancers resulting in an increase in intracellular 13-S-HODE. 15-LOX-1 and 13-S-HODE were quantified using western blots, ELISA and immunohistochemistry in 18 human colon cancers with paired normal colonic mucosa. Additionally, 15-LOX-1 expression was measured by western blots in three transformed colonic cell lines and in a human umbilical vein endothelial cell line. Next, we evaluated 13-S-HODE effects on cellular proliferation, cell cycle distribution and apoptosis in a transformed colonic cell line (RKO). Cell cycle distributions were measured by flow cytometry and apoptosis was assessed by phase contrast microscopy, electron microscopy, flow cytometry and DNA ...
  http://www.glycosciences.de/spec/lox-db/show-literature.php?lit_id=223
*  Contrasting effects of interferon gamma and interleukin 4 on responses of human vascular endothelial cells to tumour necrosis...
Tumour necrosis factor alpha (TNF-alpha) and interleukin 4 (IL-4) selectively synergise in inducing expression of the mononuclear cell adhesion receptor VCAM-1 (vascular cell adhesion molecule-1) on human umbilical vein endothelial cells (HUVEC), which results in increased adhesiveness of HUVEC for T lymphocytes. This process may be crucial for adherence of circulating lymphocytes prior to their passage from the blood into inflammatory tissues. IL-4 also amplifies production of interleukin 6 (IL-6) and monocyte chemotactic protein-(MCP-1) from TNF-alpha-activated HUVEC. In the present study we demonstrate that IL-4 enhances production of granulocyte-macrophage colony-stimulating factor (GM-CSF) from TNF-alpha-stimulated HUVEC. Moreover, using cultured adult saphenous vein and umbilical artery endothelial cells, we show identical effects of IL-4 on TNF-alpha-induced responses to those observed with endothelial cells of foetal origin. Additionally, we report here that ...
  https://www.ndorms.ox.ac.uk/publications/481715
*  Endothelial Cell Growth Kit-VEGF ATCC ® PCS-100-041™
Endothelial Cell Growth Kit-BBE (ATCC ® PCS-100-040) and Endothelial Cell Growth Kit-VEGF (ATCC ® PCS-100-041) each contain components that when added to Vascular Cell Basal Medium (ATCC ® PCS-100-030) create a complete ATCC ® Primary Cell Solution™ culture environment for endothelial cells derived from normal human large vessels (e.g., Normal Primary Human Umbilical Vein Endothelial Cells (HUVEC), ATCC ® PCS-100-010 or Primary Aortic Endothelial Cells, ATCC ® PCS-100-011). Your experimental design will dictate which Endothelial Cell Growth Kit should be used. Use of the Endothelial Cell Growth Kit-VEGF (ATCC ® PCS-100-041) will support a faster rate of proliferation because of the presence of several purified human recombinant (rh) growth factors (rh VEGF, rh EGF, rh FGF basic and rh IGF-1) combined with heparin and hydrocortisone. Use of the Endothelial Cell Growth Kit-BBE (ATCC ® PCS-100-040), which contains Bovine Brain Extract (BBE), is recommended ...
  https://atcc.org/en/Products/Cells_and_Microorganisms/Human_Primary_Cells/Primary_Cell_Culture_Reagents/PCS-100-041.aspx
*  Endothelial Cell Growth Kit-VEGF ATCC ® PCS-100-041™
Endothelial Cell Growth Kit-BBE (ATCC ® PCS-100-040) and Endothelial Cell Growth Kit-VEGF (ATCC ® PCS-100-041) each contain components that when added to Vascular Cell Basal Medium (ATCC ® PCS-100-030) create a complete ATCC ® Primary Cell Solution™ culture environment for endothelial cells derived from normal human large vessels (e.g., Normal Primary Human Umbilical Vein Endothelial Cells (HUVEC), ATCC ® PCS-100-010 or Primary Aortic Endothelial Cells, ATCC ® PCS-100-011). Your experimental design will dictate which Endothelial Cell Growth Kit should be used. Use of the Endothelial Cell Growth Kit-VEGF (ATCC ® PCS-100-041) will support a faster rate of proliferation because of the presence of several purified human recombinant (rh) growth factors (rh VEGF, rh EGF, rh FGF basic and rh IGF-1) combined with heparin and hydrocortisone. Use of the Endothelial Cell Growth Kit-BBE (ATCC ® PCS-100-040), which contains Bovine Brain Extract (BBE), is recommended ...
  https://www.atcc.org/en/Products/Culture_Reagents/Media/Specialty_Cell_Culture_Media/PCS-100-041.aspx
*  Temporal studies into attachment, VE-cadherin perturbation, and paracellular migration of human umbilical mesenchymal stem...
Mesenchymal stem cells from Wharton's jelly of human umbilical cords (WJ-MSC) are a valuable alternate source of stem cells. Their role in situ and whether they can interact and cross intact endothelial monolayers requires elucidation. The aim of this study was to investigate the dynamic interactions between WJ-MSC and human umbilical vein endothelial cells (HUVEC), including attachment, transit times, extravasation pathway, and the effects of WJ-MSC on junctional vascular endothelial (VE)-cadherin. HUVEC were grown to near confluence in endothelial media and to full confluence in mixed media before the addition of PKH26-labelled WJ-MSC. Time lapse fluorescence microscopy showed stem cells undergoing membrane blebbing followed by amoeboid movement on HUVEC monolayers before rounding up and changing shape toward the spindleshaped morphology during/after transmigration to subendothelial positions. Cells demonstrated a time lag of 60 min before paracellular extravasation, ...
  http://eprints.nottingham.ac.uk/35046/
*  HOT: Substituted oxines inhibit endothelial cell proliferation and angiogenesis - Organic & Biomolecular Chemistry Blog
In this HOT OBC paper Jun O. Liu and co-workers at Johns Hopkins University School of Medicine report structure-activity relationship studies of two oxines, which have been previously identified as hits in a high-throughput screen aimed at finding new anti-angiogenic agents, by characterising different analogues in human umbilical vein endothelial cell assays. In addition they have determined the effects of a subset of oxine derivatives on human methionine aminopeptidase and sirtuin 1 activities in endothelial cells and screened a selection of the potent inhibitors of human umbilical vein endothelial cells against two other malignant cells.. ...
  http://blogs.rsc.org/ob/2012/03/21/hot-substituted-oxines-inhibit-endothelial-cell-proliferation-and-angiogenesis/
*  GFP-Expressing Human Umbilical Vein Endothelial Cells
Ready to Grow GFP Expressing HUVECs. Designed for the study of angiogenesis and vascular related disorders. Cells can be doubled > 18 fold
  http://www.neuromics.com/ittrium/visit/A1x66x1y1x85b0x1x9dy1x6230x1y1x628dx1x82y1x9efex1x82y1x9effx1x69y1x11ad4x1x8ey1x11adfx1x8ey1xb299x1x7f
*  Development of Endothelium-Denuded Human Umbilical Veins as Living Scaffolds for Tissue-Engineered Small Caliber Vascular...
URN zum Zitieren dieses Dokuments: urn:nbn:de:bvb:355-epub-224348. Hoenicka, Markus, Schrammel, Siegfried, Bursa, Jiri, Huber, Georgine, Bronger, Holger, Schmid, Christof und Birnbaum, Dietrich E. (2011) Development of Endothelium-Denuded Human Umbilical Veins as Living Scaffolds for Tissue-Engineered Small Caliber Vascular Grafts. Journal of Tissue Engineering and Regenerative Medicine ...
  https://epub.uni-regensburg.de/22434/
*  UK Against Fluoridation: October 2016
Excessive amount of inorganic arsenic (iAs) and fluoride (F) coexist in drinking water in many regions, which is associated with high risk of vascular diseases. However, the underlying mechanisms are not well studied. The present study was to evaluate the effects of iAs and F individual or combined exposure on endothelial activation and apoptosis in vitro. Primary human umbilical vein endothelial cells (HUVECs) were exposed to 5 μM As2O3 and/or 1 mM NaF. Changes in endothelial cell apoptosis, inflammation, oxidative stress and nitric oxide (NO) production were analyzed. The results showed that iAs and/or F induced significant increase in endothelial cell apoptosis and inflammation as indicated by the increase of mRNA and protein expression of vascular cell adhesion molecule-1, intercellular adhesion molecule-1, and pentraxin 3. Furthermore, iAs and/or F exposure induced intracellular reactive oxygen species and malondialdehyde generation. Results showed iAs and/or F exposure increased the ...
  http://ukagainstfluoride.blogspot.com/2016_10_01_archive.html
*  Plus it
2573 We have found that SU6668 [a tyrosine kinase inhibitor of vascular endothelial growth factor receptor 2 (VEGFR-2/KDR), fibroblast growth factor receptor 1 (FGFR-1) and platelet-derived growth factor receptor β (PDGFRβ )] in combination with paclitaxel resulted in a higher response than either of the single agents alone when administered to nude mice transplanted with human ovarian carcinoma (1A9). To elucidate these studies, we have evaluated the relative contribution of the host and tumor cells on their sensitivity to this combination. We performed in vitro studies on human umbilical vein endothelial cells (HUVEC), human microvascular endothelial cells (HMVEC), aortic smooth muscle cells (AoSMC) and 1A9 tumor cells. For this purpose were utilized the receptor tyrosine kinase (RTK) inhibitors SU6668, and SU5416 (an inhibitor of VEGFR-2/KDR) in combination with paclitaxel (PTX) and cisplatin (DDP). Concentrations of the RTK inhibitor and the cytotoxic agent ranging from IC50 to IC0, were ...
  http://cancerres.aacrjournals.org/content/64/7_Supplement/594.3
*  Endothelial cell adhesion to the fibronectin CS5 domain in artificial extracellular matrix proteins.
Abstract This study examines the spreading and adhesion of human umbilical vein endothelial cells (HUVEC) on artificial extracellular matrix (aECM) proteins containing sequences de..
  https://www.omicsonline.org/references/endothelial-cell-adhesion-to-the-fibronectin-cs5-domain-in-artificial-extracellular-matrix-proteins-621622.html
*  Plus it
Materials. Human umbilical vein endothelial cells (HUVEC) were obtained from American Type Culture Collection (ATCC; Rockville, MD) and used within four passages. Endothelial cells were cultured in Medium 199 (Life Technologies, Inc., Grand Island, NY) supplemented with 2 mmol/L l-glutamine, 1 unit/mL penicillin, 10 μg/mL streptomycin, 5 units/mL heparin, 200 μg/mL endothelial cell growth supplement (Collaborative Research, Inc., Bedford, MA), and 20% bovine serum (HyClone, Logan, UT). Rat mAbs E26, E19, and E3 are directed against human placental DPP4; rat mAbs D8 and D28 against human placental seprase ( 26, 33); rat mAb C27 against human melanoma β1 integrin; and rat mAb C37 against a 90-kDa cell-surface glycoprotein gp-90 ( 25). Common protease inhibitors, including EDTA (an inhibitor of metalloproteinases) and 4-(2-aminoethyl)benzenesulfonylfluoride (AEBSF; an inhibitor of serine proteases), were used to assist in identifying DPP4 and seprase in gelatin zymography and prolyl dipeptidase ...
  http://cancerres.aacrjournals.org/content/66/9/4652
*  Plus it
Two independent studies associated the human AT2 gene 1675 G/A PM with left ventricular structure and recurrent coronary ischemia (15, 37). Because the PM is located in an intronic splice branch site, it was postulated that it might affect pre-mRNA splicing and thereby AT2 receptor expression. However, this hypothesis had not been verified convincingly. Therefore, we determined the effect of the PM systematically in 1) in vitro transfection experiments and 2). ex vivo by comparison of the myocardial AT2 splice patterns with the genotypes of 12 patients with heart failure.. In spite of careful investigation by many researchers, the function of AT2 in cardiovascular cells has not yet been completely clarified. In earlier studies, we overexpressed the human AT2 receptor in porcine cardiac fibroblasts (PC12) and human umbilical vein endothelial cells. Overexpression of AT2 receptors in these cells, which did not exhibit a native AT2, led to a 6- to 10-fold higher expression of AT2 compared with ...
  http://ajpregu.physiology.org/content/289/6/R1729
*  Estradiol-17β and Its Cytochrome P450- and Catechol-O-Methyltransferase-Derived Metabolites Stimulate Proliferation in Uterine...
The key novel findings observed from this study are as follows: (1) UAECs express CYP1A1, CYP1A2, CYP1B1, CYP3A4, and COMT; (2) E2β, 2-OHE2, 4-OHE2, and 4-ME2 stimulate P-UAEC but not NP-UAEC proliferation; and (3) E2β-induced cell proliferative responses are mediated primarily via ER-β, whereas E2β metabolite-induced proliferative responses are independent of ER-α and ER-β.. UAECs constitutively express enzymes that may metabolize E2β to its hydroxy (CYP1A1, CYP1A2, CYP3A4, and CYP1B1) and subsequently methoxy (COMT) metabolites. Consistent with our findings are reports showing that CYP450s and COMT are expressed in aortic, coronary artery, and umbilical vein ECs.11,16-18 However, this is the first characterization of the localized intracellular expression of CYP450s in endothelial cells. Our data also confirm findings that COMT is primarily an intracellular cytosolic enzyme.19 Although little is known about the intracellular localization of these enzymes in endothelial cells, it is ...
  http://hyper.ahajournals.org/content/55/4/1005
*  Umbilical Cable, Umbilical Cable Suppliers and Manufacturers at Alibaba.com
Alibaba.com offers 195 umbilical cable products. About 38% of these are power cables, 24% are electrical wires, and 7% are other wires, cables & cable assemblies. A wide variety of umbilical cable options are available to you, such as low voltage, high voltage, and insulated.
  http://www.alibaba.com/showroom/umbilical-cable.html
*  SEACON 2013 - SEACON
Jumper Assemblies - hose conduit with optical or electrical connectors at either end. Key elements in both optical and electrical distribution systems are:. • Jumper Assemblies - Hose conduit with optical or electrical connectors at either end.. • Distribution Harness - Can have multiple "legs" with either connectors or sensors terminated to the end of each leg.. • Umbilical Termination Assemblies - Provide the interface between the optical or electrical element of the umbilical and SEACON wetmate connector(s).. • Cable Hang-Offs - Specially designed cable strength member terminations that provide support for the individual cable elements at the top side of some umbilical cables.. • Abandonment Caps or Connectors - When the top side of an umbilical needs to be abandoned subsea for a period, these provide watertight protection of the umbilical cable.. Although many design features make these products successful, highlights ...
  http://seaconworldwide.com/2013/
*  HUVEC/SMC/fibroblast-laden PCL tube
Page contains details about HUVEC/SMC/fibroblast-laden PCL tube . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
  http://nano.nature.com/nano/GR-M9522098