*  Plus it
... or truncated V2 and CCR5 receptor mutants with their wild-type counterparts resulted in mislocalization of the wild-type ... domains of the human B1 and B2 bradykinin receptor subtypes determine receptor coupling efficacy to Gq-mediated phospholipase C ... In A and B, cells were transfected with 2 μg of wild type B1 receptor DNA in the absence and presence of varying amounts of ... The best support for such a mechanism is provided by the GABAB receptor system, where both the type 1 and 2 are required for ...
  http://molpharm.aspetjournals.org/content/67/1/309
*  Adenoprotection of the heart involves phospholipase C-induced activation and translocation of PKC-ε to RACK2 in adult rat and...
Li Q, Lau A, Morris TJ, Guo L, Fordyce CB, Stanley EF. A syntaxin 1, Gαo, and N-type calcium channel complex at a presynaptic ... Kamp TJ, Hell JW. Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C. Circ Res 87: 1095- ... Adenoprotection of the heart involves phospholipase C-induced activation and translocation of PKC-ε to RACK2 in adult rat and ... Adenoprotection of the heart involves phospholipase C-induced activation and translocation of PKC-ε to RACK2 in adult rat and ...
  http://ajpheart.physiology.org/content/297/2/H718.long
*  small wing encodes a phospholipase C-(gamma) that acts as a negative regulator of R7 development in Drosophila | Development
Phospholipase C-(gamma) (PLC-(gamma)) is activated in many cell types following growth factor stimulation. Our understanding of ... small wing encodes a phospholipase C-(gamma) that acts as a negative regulator of R7 development in Drosophila ... small wing encodes a phospholipase C-(gamma) that acts as a negative regulator of R7 development in Drosophila ... small wing encodes a phospholipase C-(gamma) that acts as a negative regulator of R7 development in Drosophila ...
  http://dev.biologists.org/content/125/24/5033
*  Anti-Secretory phospholipase A2 Type V antibody (ab97847) References
References for Abcam's Anti-Secretory phospholipase A2 Type V antibody (ab97847). Please let us know if you have used this ... By product type. Proteins and Peptides. Proteomics tools. Agonists, activators, antagonists and inhibitors. Lysates. Multiplex ... By product type. Primary antibodies. Secondary antibodies. ELISA, Matched Antibody Pairs and Multiplex Immunoassays. Cell and ...
  http://www.abcam.com/secretory-phospholipase-a2-type-v-antibody-ab97847-references.html
*  Cholesterol relieves the inhibitory effect of sphingomyelin on type II secretory phospholipase A2 | Biochemical Journal
Cholesterol relieves the inhibitory effect of sphingomyelin on type II secretory phospholipase A2. Kamen S. KOUMANOV, Peter J. ... Secretory type II phospholipase A2 (sPLA2) is inhibited by sphingomyelin (SPH); cholesterol either mixed with the model ... Cholesterol relieves the inhibitory effect of sphingomyelin on type II secretory phospholipase A2 ... Cholesterol relieves the inhibitory effect of sphingomyelin on type II secretory phospholipase A2 ...
  http://www.biochemj.org/content/336/3/625
*  284 Clinical usefulness of quantitative measurement of anti-m-type phospholipase a2 receptor antibodies in patients with...
Background and aims Autoantibodies to M-type phospholipase A2 receptor (PLA2R) are specific markers of idiopathic membranous ... 284 Clinical usefulness of quantitative measurement of anti-m-type phospholipase a2 receptor antibodies in patients with ... 284 Clinical usefulness of quantitative measurement of anti-m-type phospholipase a2 receptor antibodies in patients with ...
  http://lupus.bmj.com/content/4/Suppl_1/A130.2
*  Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective...
Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective ... Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective ... Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective ... Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective ...
  https://www.ncbi.nlm.nih.gov/pubmed/24210353
*  G Protein beta subunit types differentially interact with a muscarinic receptor but not adenylyl cyclase type II or...
... phospholipase C-beta2, phospholipase C-beta3, and adenylyl cyclase type II. beta(4)gamma(2) and beta(1)gamma(2) activated all ... Among the five G protein beta subunits known, the beta(4) subunit type is the least studied. We compared the ability of ... these results show that the beta subunit type plays a direct role in the receptor activation of a G protein. ... Protein beta subunit types differentially interact with a muscarinic receptor but not adenylyl cyclase type II or phospholipase ...
  https://www.semanticscholar.org/paper/G-Protein-beta-subunit-types-differentially-with-a-Hou-Chang/3ac4ec454d957b34c8881f3c5446c3a5a41dfe33
*  Lipoprotein-Associated Phospholipase A2 Mass Level Is Increased in Elderly Subjects with Type 2 Diabetes Mellitus
... and clinical studies related to type 1 and type 2 diabetes. The journal welcomes submissions focusing on the epidemiology, ... Lipoprotein-Associated Phospholipase A2 Mass Level Is Increased in Elderly Subjects with Type 2 Diabetes Mellitus. J. Fortunato ... D. Y. Hui, "Phospholipase A2 enzymes in metabolic and cardiovascular diseases," Current Opinion in Lipidology, vol. 23, no. 3, ... P. B. Gorelick, "Lipoprotein-associated phospholipase A2 and risk of stroke," The American Journal of Cardiology, vol. 101, no ...
  https://www.hindawi.com/journals/jdr/2014/278063/ref/
*  Angiotensin II Type 2 Receptor Stimulation of Neuronal Delayed-Rectifier Potassium Current Involves Phospholipase A2 and...
Angiotensin II Type 2 Receptor Stimulation of Neuronal Delayed-Rectifier Potassium Current Involves Phospholipase A2 and ... Angiotensin II Type 2 Receptor Stimulation of Neuronal Delayed-Rectifier Potassium Current Involves Phospholipase A2 and ... Angiotensin II Type 2 Receptor Stimulation of Neuronal Delayed-Rectifier Potassium Current Involves Phospholipase A2 and ... Angiotensin II Type 2 Receptor Stimulation of Neuronal Delayed-Rectifier Potassium Current Involves Phospholipase A2 and ...
  http://www.jneurosci.org/content/18/2/679
*  Protein kinase C mediates delayed inhibitory feedback regulation of human neurokinin type 1 receptor activation of...
... kinase C mediates delayed inhibitory feedback regulation of human neurokinin type 1 receptor activation of phospholipase C in ... Item Type:. Article Subjects:. University of Westminster , Science and Technology , Life Sciences, School of (No longer in use) ... kinase C mediates delayed inhibitory feedback regulation of human neurokinin type 1 receptor activation of phospholipase C in ... Delayed inhibitory feedback by PKC may be mediated by phosphorylation of phospholipase C, although an additional site of action ...
  http://westminsterresearch.wmin.ac.uk/10861/
*  Biomarkers in Kidney Disease | Vinood B. Patel | Springer
M-Type Phospholipase A2 Receptor as a Biomarker in Kidney Disease. Hoxha, Elion (et al.) ...
  http://www.springer.com/us/book/9789400776982
*  Membranous glomerulonephritis - Wikipedia
One study has identified antibodies to an M-type phospholipase A2 receptor in 70% (26 of 37) cases evaluated.[2] In 2014, a ... "M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy". The New England Journal of Medicine. ... "Thrombospondin type-1 domain-containing 7A in idiopathic membranous nephropathy". The New England Journal of Medicine. 371 (24 ... second autoantigen was discovered, the thrombospondin type 1 domain-containing 7A (THSD7A) system that might account for an ...
  https://en.wikipedia.org/wiki/Membranous_nephritis
*  ASMscience | Western Blot Analysis fo
M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy. N Engl J Med 361:11-21.[CrossRef].[ ... of the anti-phospholipase A2 receptor type. Lane 2 shows a negative control at 1:20 dilution from an ANCA-positive patient. On ... of the anti-phospholipase A2 receptor type. Lane 2 shows a negative control at 1:20 dilution from an ANCA-positive patient. On ... Induction of anti-GBM nephritis in rats by recombinant alpha 3(IV)NC1 and alpha 4(IV)NC1 of type IV collagen. Kidney Int 53:664 ...
  http://www.asmscience.org/content/book/10.1128/9781555818722.ch42
*  Identification of ISC1 (YER019w) as inositol phosphosphingolipid phospholipase C in Saccharomyces cerevisiae.
Phospholipases; EC 3.1.4.-/ISC1 protein, S cerevisiae; EC 3.1.4.-/Type C Phospholipases; EC 3.1.4.12/Sphingomyelin ... Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. ... Phospholipases / chemistry*, genetics. Plasmids / metabolism. Saccharomyces cerevisiae / enzymology*. Saccharomyces cerevisiae ... Here we show that ISC1 (YER019w), which has homology to bacterial neutral sphingomyelinase (SMase), encodes IPS phospholipase C ...
  http://www.biomedsearch.com/nih/Identification-ISC1-YER019w-as-inositol/11006294.html
*  Membranous nephropathy - Symptoms and causes - Mayo Clinic
Clinical usefulness of autoantibodies to M-type phospholipase A2 receptor (PLA2R) for monitoring disease activity in idiopathic ... Often, membranous nephropathy results from some type of autoimmune activity. Your body's immune system mistakes healthy tissue ... PLA2R: Phospholipase A2 Receptor Antibodies, Serum. Mayo Medical Laboratories. http://www.mayomedicallaboratories.com/test- ...
  https://www.mayoclinic.org/diseases-conditions/membranous-nephropathy/symptoms-causes/syc-20365189
*  PLA2R1 - Wikipedia
Secretory phospholipase A2 receptor is an enzyme that in humans is encoded by the PLA2R1 gene. M-type phospholipase A2 receptor ... "M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy". The New England Journal of Medicine. ... "Structural comparison of phospholipase-A2-binding regions in phospholipase-A2 receptors from various mammals". European Journal ... "Entrez Gene: PLA2R1 phospholipase A2 receptor 1, 180kDa". Beck LH, Bonegio RG, Lambeau G, Beck DM, Powell DW, Cummins TD, Klein ...
  https://en.wikipedia.org/wiki/PLA2R1
*  Membranous glomerulopathy - The Clinical Advisor
There is new clinical research linking the development of IMN to SNPs in the M-type phospholipase A2 receptor protein in the ... In adults, over 70% of cases are secondary to antibodies to M-type phospholipase A2 receptor. The role of this antigen in ... It is now believed that over 70% of cases arise secondary to antibodies to the M-type phospholipase A2 receptor. There are ... The SNPs in the M-type phospholipase A2 receptor and HLA DQA1 gene loci may increase the likelihood of autoantibody production ...
  http://www.clinicaladvisor.com/pediatrics/membranous-glomerulopathy/article/622078/
*  Phospholipase C gamma Summary Report | CureHunter
It is structurally related to PHOSPHOLIPASE C DELTA with the addition of SRC HOMOLOGY DOMAINS and pleckstrin homology domains ... A phosphoinositide phospholipase C subtype that is primarily regulated by PROTEIN-TYROSINE KINASES. ... Phospholipases: 1677*Type C Phospholipases: 869*Phosphoinositide Phospholipase C: 92*Phospholipase C gamma: 118*Drosophila SL ... Phospholipase C gamma 2; Phospholipase C gamma D; Phospholipase C gamma1; Phospholipase C gamma2; Phospholipase C gammaD; PLC ...
  http://www.curehunter.com/public/keywordSummaryD051966-Phospholipase-C-gamma.do
*  Membranous glomerulonephritis - Wikipedia
One study has identified antibodies to an M-type phospholipase A2 receptor in 70% (26 of 37) cases evaluated. Other studies ... July 2, 2009). "M-Type Phospholipase A2 Receptor as Target Antigen in Idiopathic Membranous Nephrovv pathy". The New England ...
  https://en.wikipedia.org/wiki/Membranous_glomerulonephritis
*  BCR activation induces integrin α4β1-mediated B cell | Open-i
... phospholipase C (PLC)gamma2, IP3R-mediated Ca2+ release, and PKC.In contrast, activation of mitogen-activated protein kinase ... License Type *Attribution. *Attribution noncommercial. *Attribution noncommercial no derivatives. *Attribution noncommercial ... phospholipase C (PLC)gamma2, IP3R-mediated Ca2+ release, and PKC. In contrast, activation of mitogen-activated protein kinase ... phospholipase C (PLC)gamma2, IP3R-mediated Ca2+ release, and PKC.In contrast, activation of mitogen-activated protein kinase ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2194118_20011866f1&req=4
*  Ca2+]i in cells expressing the chimeric FcγRIIIB/CD7. | Open-i
Phospholipase C gamma. *Phosphorylation. *Recombinant Proteins/metabolism. *Signal Transduction. *Type C Phospholipases/ ... While many cell types express receptors for the Fc domain of IgG (Fc gamma R), only primate polymorphonuclear neutrophils (PMN ... While many cell types express receptors for the Fc domain of IgG (Fc gamma R), only primate polymorphonuclear neutrophils (PMN ... since the FcγRIIIB/CD7 molecule was expressed at a greater level than the wild-type FcγRIIIB (Fig. 1, top and middle). This ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2140207_JCB.12436f3&req=4
*  PLCB2 elisa kit | Porcine 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta-2 ELISA Kit-NP 001271227.1
Protein type: Phospholipase; Carbohydrate Metabolism - inositol phosphate; EC 3.1.4.11. Chromosomal Location of Human Ortholog ... Phosphoinositide phospholipase C-beta-2; Phospholipase C-beta-2; PLC-beta-2. ... Molecular Function: calcium ion binding; phosphoinositide phospholipase C activity; phospholipase C activity; signal transducer ... Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays ...
  https://www.mybiosource.com/prods/ELISA-Kit/Porcine/1-phosphatidylinositol-4-5-bisphosphate-phosphodiesterase-beta-2/PLCB2/datasheet.php?products_id=2604862
*  Amelioration of Glucolipotoxicity-Induced Endoplasmic Reticulum Stress by a "Chemical Chaperone" in Human THP-1 Monocytes
... and clinical studies related to type 1 and type 2 diabetes. The journal welcomes submissions focusing on the epidemiology, ... Among the TRPC subfamily of TRP channels, TRPC6 is gated by signal transduction pathways that activate C-type phospholipases as ... D. R. Laybutt, A. M. Preston, M. C. Åkerfeldt et al., "Endoplasmic reticulum stress contributes to beta cell apoptosis in type ... P. Marchetti, M. Bugliani, R. Lupi et al., "The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients," ...
  https://www.hindawi.com/journals/jdr/2012/356487/