*  Tryptophan synthase, alpha chain (IPR002028) | InterPro | EMBL-EBI
Tryptophan synthase (EC:4.2.1.20) catalyzes the last step in the biosynthesis of tryptophan [PMID: 2679363, PMID: 1366510]: L- ... A gene encoding the tryptophan synthase beta subunit of Arabidopsis thaliana.. Proc. Natl. Acad. Sci. U.S.A. 86 4604-8 1989 ... The tryptophan synthase multienzyme complex: exploring structure-function relationships with X-ray crystallography and ... Nucleotide sequence of the Neurospora crassa trp-3 gene encoding tryptophan synthetase and comparison of the trp-3 polypeptide ...
  http://www.ebi.ac.uk/interpro/entry/IPR002028
*  Lanoot R-8695 Strain Passport - StrainInfo
Streptomyces lydicus strain AS 4.1412 tryptophan synthase beta subunit (trpB) gene, partial cds. AS 4.1412. T ... Streptomyces lydicus partial gluS-FD gene for ferredoxin dependent glutamate synthase, strain NRRL 2433. NRRL 2433. T ... Streptomyces lydicus strain AS 4.1412 ATP synthase beta subunit (atpD) gene, partial cds. AS 4.1412. T ... Streptomyces lydicus partial gluS-alpha gene for NADPH glutamate synthase alpha subunit and partial gluS-beta gene for NADPH ...
  http://www.straininfo.net/strains/55754
*  Tryptophan synthase - Wikipedia
Tryptophan synthase or tryptophan synthetase is an enzyme that catalyzes the final two steps in the biosynthesis of tryptophan ... The active sites of tryptophan synthase are allosterically coupled. Subunits: Tryptophan synthase typically exists as an α-ββ-α ... "Tryptophan synthase: Identification of Pasteurella multocida tryptophan synthase B-subunit by antisera against strain PI059". ... Synthase Lyase Tryptophan synthase (indole-salvaging) Molecular and Cellular Biology portal. ...
  https://en.wikipedia.org/wiki/Tryptophan_synthase
*  Tryptophan synthase (indole-salvaging) - Wikipedia
Tryptophan synthase (indole-salvaging) (EC 4.2.1.122, tryptophan synthase beta2) is an enzyme with systematic name L-serine ... H2O This enzyme salvages the lost indole to L-tryptophan. Hettwer, S.; Sterner, R. (2002). "A novel tryptophan synthase β- ... Tryptophan synthase (indole-salvaging) at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and ... hydro-lyase (adding indole, L-tryptophan-forming). This enzyme catalyses the following chemical reaction L-serine + indole ⇌ {\ ...
  https://en.wikipedia.org/wiki/Tryptophan_synthase_(indole-salvaging)
*  Tryptophan synthase beta chain/beta chain-like (IPR023026) | InterPro | EMBL-EBI
Tryptophan synthase beta chain/beta chain-like (IPR023026) *Tryptophan synthase, beta chain (IPR006654) ... Tryptophan synthase catalyzes the last step in the biosynthesis of tryptophan [PMID: 2679363, PMID: 1366510]: L-serine + 1-( ... Tryptophan synthase beta chain/beta chain-like (IPR023026). Short name: Trp_synth_beta/beta-like ... In every other case so far, either the species appears not to make tryptophan (there is no trp synthase alpha subunit), or a ...
  http://www.ebi.ac.uk/interpro/entry/IPR023026
*  tryptophan synthase activity QuickView - Correlation Engine
A proximal tryptophan in NO synthase controls activity by a novel mechanism. ... Factors affecting the biosynthesis of L-tryptophan by genetically modified strains of Escherichia co… ...
  http://www.nextbio.com/b/search/ov/tryptophan%20synthase%20activity?id=33350&type=biogroup
*  Tryptophan synthase | definition of tryptophan synthase by Medical dictionary
What is tryptophan synthase? Meaning of tryptophan synthase medical term. What does tryptophan synthase mean? ... Looking for online definition of tryptophan synthase in the Medical Dictionary? tryptophan synthase explanation free. ... tryptophan synthase. Also found in: Wikipedia. tryp·to·phan syn·thase. a nonmammalian hydro-lyase condensing l-serine indole-3- ... Tryptophan synthase , definition of tryptophan synthase by Medical dictionary https://medical-dictionary.thefreedictionary.com/ ...
  https://medical-dictionary.thefreedictionary.com/tryptophan+synthase
*  RCSB PDB - Protein Feature View - Tryptophan synthase beta chain - B7LS19 (TRPB ESCF3)
L-serine + 1-C-indol-3-ylglycerol 3-phosphate = L-tryptophan + D-glyceraldehyde 3-phosphate + H2O. UniProt ... The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. UniProt ...
  http://www.rcsb.org/pdb/protein/B7LS19
*  RCSB PDB - Protein Feature View - Tryptophan synthase alpha chain - B7N473 (TRPA ECOLU)
L-serine + 1-C-indol-3-ylglycerol 3-phosphate = L-tryptophan + D-glyceraldehyde 3-phosphate + H2O. UniProt ...
  http://www.rcsb.org/pdb/protein/B7N473
*  Non-Thermal Radio Frequency Stimulation Inhibits the Tryptophan Synthase Beta Subunit in the Algae Chlamydomonas reinhardtii
We inhibited the synthesis of the enzyme tryptophan synthase beta subunit (MAA7) by applying the signal derived from a ... because less 5-Fluoroin-dole can be converted to the toxic 5-Fluoro-L-tryptophan (5-FT). We find a 24% (±5%) increase of growth ... Ultra Low Radio Frequency Energy, ulRFE, siRNA, Oil Production, Nativis Technology, MAA7: Beta Subunit of Tryptophan Synthase, ... We inhibited the synthesis of the enzyme tryptophan synthase beta subunit (MAA7) by applying the signal derived from a ...
  http://www.scirp.org/Journal/PaperInformation.aspx?PaperID=76509
*  Characterisation of the tryptophan synthase alpha subunit in maize | BMC Plant Biology | Full Text
It catalyzes the tryptophan synthase α-reaction (cleavage of IGP), and forms a tryptophan synthase complex with ZmTSB1 in vitro ... tryptophan is synthesized from indole-3-glycerole phosphate (IGP) by a tryptophan synthase αββα heterotetramer. Plants have ... A 160 kD tryptophan synthase complex was partially purified from maize leaves and ZmTSA was identified as native α-subunit of ... It was demonstrated in vivo and in vitro that maize forms a tryptophan synthase complex and ZmTSA functions as α-subunit in ...
  https://0-bmcplantbiol-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/1471-2229-8-44
*  Sodium in the structure of Crystal Structure Of the Beta-SER178PRO Mutant of Tryptophan Synthase (pdb 1k7x)
Crystal Structure Of the Beta-SER178PRO Mutant of Tryptophan Synthase ... The binding sites of Sodium atom in the structure of Crystal Structure Of the Beta-SER178PRO Mutant of Tryptophan Synthase (pdb ... Sodium in the structure of Crystal Structure Of the Beta-SER178PRO Mutant of Tryptophan Synthase (pdb 1k7x). ...
  http://sodium.atomistry.com/pdb1k7x.html
*  Effect of endotoxin on tryptophan pyrrolase and delta-aminolaevulinate synthase: evidence for an endogenous regulatory haem...
Effect of endotoxin on tryptophan pyrrolase and delta-aminolaevulinate synthase: evidence for an endogenous regulatory haem ... Effect of endotoxin on tryptophan pyrrolase and delta-aminolaevulinate synthase: evidence for an endogenous regulatory haem ... Effect of endotoxin on tryptophan pyrrolase and delta-aminolaevulinate synthase: evidence for an endogenous regulatory haem ... Effect of endotoxin on tryptophan pyrrolase and delta-aminolaevulinate synthase: evidence for an endogenous regulatory haem ...
  http://www.biochemj.org/content/166/2/301
*  Substrate channeling - Wikipedia
... this is seen in tryptophan synthase. A third possibility is by a charged region on the surface of the enzyme acting as a ... This is seen in the bifunctional enzyme dihydrofolate reductase-thymidylate synthase. The channeling of aminoacyl-tRNA for ...
  https://en.wikipedia.org/wiki/Substrate_channeling
*  Hypertryptophanemia - Wikipedia
Dunn MF, Niks D, Ngo H, Barends TR, Schlichting I (June 2008). "Tryptophan synthase: the workings of a channeling nanomachine ... A product of the bacterial biosynthesis of tryptophan is indole. The excess of tryptophan in hypertryptophanemia also results ... "Allosteric effects acting over a distance of 20-25 A in the Escherichia coli tryptophan synthase bienzyme complex increase ... Tryptophan is an essential amino acid, and is required for protein synthesis. Aside from this crucial role, the remainder of ...
  https://en.wikipedia.org/wiki/Hypertryptophanemia
*  KEGG T01622: SLG 13710
GenBank) tryptophan synthase beta chain. KO. K01696 tryptophan synthase beta chain [EC:4.2.1.20] ... 00400 Phenylalanine, tyrosine and tryptophan biosynthesis. SLG_13710 (trpB). Enzymes [BR:ssy01000]. 4. Lyases. 4.2 Carbon- ...
  http://www.genome.jp/dbget-bin/www_bget?ssy:SLG_13710
*  Tryptophan - Wikipedia
In the last step, tryptophan synthase catalyzes the formation of tryptophan from indole and the amino acid serine. The ... The conversion is catalyzed by the enzyme tryptophan synthase. Amino acids, including tryptophan, are used as building blocks ... So high levels of tryptophan prevent tryptophan synthesis through a negative feedback loop, and when the cell's tryptophan ... Hopkins recovered tryptophan from hydrolysed casein, recovering 4-8 g of tryptophan from 600 g of crude casein. As an essential ...
  https://en.wikipedia.org/wiki/Tryptophan
*  Overview: trpA, Pseudomonas aeruginosa UCBPP-PA14
tryptophan synthase subunit alpha Evidence for Translation. Charge (pH 7). -8.37 Kyte-Doolittle Hydrophobicity Value. 0.058 ...
  http://pseudomonas.com/feature/show/?locus_tag=PA14_00440
*  US20070004907A1 - Genes conferring herbicide resistance - Google Patents
22(6):789-810); tryptophan synthase (Zhao et al. (1995) J. Biol. Chem. 270(11):6081-6087); plastocyanin (Lawrence et al. (1997 ... Novel EPSP synthase gene with herbicide resistance US9045765B2 (en) 2006-06-09. 2015-06-02. Athenix Corporation. EPSP synthase ... Furthermore, the sequences of known EPSP synthases do not predict all sequences capable of functioning to encode EPSP synthase ... However, certain bacterial EPSP synthases have high tolerances to glyphosate. Several such bacterial EPSP synthase have been ...
  https://patents.google.com/patent/US20070004907A1/en
*  Maize inbred PH25M1 - PIONEER HI-BRED INTERNATIONAL, INC.
6,441,274 (plant tryptophan synthase beta subunit), U.S. Pat. No. 6,346,403 (methionine metabolic enzymes), U.S. Pat. No. ... D) Acetohydroxy acid synthase, which has been found to make plants that express this enzyme resistant to multiple types of ... B) Glyphosate (tolerance imparted by mutant 5-enolpyruvl-3-phosphikimate synthase (EPSP) and aroA genes, respectively) and ...
  http://www.freepatentsonline.com/9237702.html
*  Bx1 benzoxazin1 - Wikipedia
One is encoded by the gene tsa1, tryptophan synthase alpha1(Frey et al. 1997, Melanson et al. 1997 ), on chromosome 7, another ... The X-ray structure of BX1 protein has been resolved and compared with bacterial TSA (tryptophan synthase alpha subunit, Kulik ... Molecular characterization reveals that the BX1 protein is a homologue to the alpha-subunit of tryptophan synthase. The ... "On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase (TSA) from ...
  https://en.wikipedia.org/wiki/Bx1_benzoxazin1
*  RCSB PDB - 1A5B: CRYO-CRYSTALLOGRAPHY OF A TRUE SUBSTRATE, INDOLE-3-GLYCEROL PHOSPHATE, BOUND TO A MUTANT (ALPHA D60N...
... tryptophan synthase alpha2beta2 complex reveals the correct orientation of active site alphaGlu49. ... Tryptophan synthase beta subunit-like PLP- dependent enzymes Tryptophan synthase beta subunit-like PLP- dependent enzymes ... Tryptophan synthase beta subunit-like PLP- dependent enzymes Tryptophan synthase, beta-subunit Salmonella typhimurium [TaxId: ... Tryptophan biosynthesis enzymes Trp synthase alpha-subunit Salmonella typhimurium [TaxId: 90371] B. d1a5bb_. Alpha and beta ...
  http://www.rcsb.org/pdb/explore/derivedData.do?structureId=1A5B
*  US8431799B1 - Soybean cultivar 12245180 - Google Patents
6,441,274 (plant tryptophan synthase beta subunit); U.S. Pat. No. 6,346,403 (methionine metabolic enzymes); U.S. Pat. No. ... plant 5-enolpyruvylshikimate-3-phosphate synthase, and plant acetolactate synthase (Eichholtz, et al., Somatic Cell Mol. Genet ... D. Acetohydroxy acid synthase, which has been found to make plants that express this enzyme resistant to multiple types of ... B. Glyphosate (resistance conferred by mutant 5-enolpyruvlshikimate-3-phosphate synthase (EPSPS) and aroA genes, respectively) ...
  https://patents.google.com/patent/US8431799B1/en
*  Frontiers | Archaeal Persisters: Persister Cell Formation as a Stress Response in Haloferax volcanii | Microbiology
Further research could explore the role of tryptophan and tryptophan-inducible gene expression in persister formation in H. ... is an AHL synthase in this species. It has also been shown that diketopiperazines produced by the halophilic archaeon ... as did the addition of tryptophan. Kwan et al. (2015b) showed that production of DosP (direct oxygen sensing phosphodiesterase ... with expression increasing rapidly following the addition of tryptophan to the medium (Large et al., 2007). ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2017.01589/full