*  Formation of Complex and Unstable Chromosomal Translocations in Yeast - Semantic Scholar
Unstable dicentric translocations continuously gave rise to clones with multiple translocations in various combinations, ... Here, the chromosomal location, copy number and sequence similarity of the translocation targets ALP1 and LYP1 were altered to ... Breakpoint sequencing and mapping showed that the formation of complex translocation types is strictly dependent on the ... Among 844 clones with chromosomal rearrangements, 93 with various types of simple and complex translocations involving CAN1, ...
  https://www.semanticscholar.org/paper/Formation-of-Complex-and-Unstable-Chromosomal-Tran-Schmidt-Viebranz/0ac76d8a8ad80b25a5b92f09a6e9396a40f74aba
*  Enzyme That Mutates Antibodies Also Targets Cancer-Causing Gene
AID »Antibodies »DNA »Enzym »c-Myc »cancer-causing »gene mutator »genetic malfunction »immune system »lymphoma »lymphomas » ... A very specific translocation causes Burkitt's lymphoma, a cancer that plagues children in equatorial Africa. It involves a DNA ... Further reports about: , AID , Antibodies , DNA , Enzym , c-Myc , cancer-causing , gene mutator , genetic malfunction , immune ... By looking for -- and not finding -- the specific translocation in these mice, he showed that c-myc had to be active in order ...
  http://www.innovations-report.com/html/reports/life-sciences/enzyme-mutates-antibodies-targets-cancer-causing-124312.html
*  High resolution copy number analysis of IRF4 translocation-positive diffuse large B-cell and follicular lymphomas - Zurich...
Overall this study unravels a recurrent pattern of secondary genetic alterations in IRF4 translocation-positive lymphomas. ... Overall this study unravels a recurrent pattern of secondary genetic alterations in IRF4 translocation-positive lymphomas. ... Translocations affecting chromosome subband 6p25.3 containing the IRF4 gene have been recently described as characteristic ... Translocations affecting chromosome subband 6p25.3 containing the IRF4 gene have been recently described as characteristic ...
  http://www.zora.uzh.ch/id/eprint/76318/
*  Selective Chromatid Segregation Mechanism Explains the Etiology of Chromosome 11 Translocation-Associated Psychotic Disorders:...
Selective Chromatid Segregation Mechanism Explains the Etiology of Chromosome 11 Translocation-Associated Psychotic Disorders: ... 11 translocations associated with psychosis found in three families provide the only convincing evidence for the genetic ... The translocations we propose might cause random segregation of its sister chromatids to explain the result of 50% penetrance. ... The paradoxes we try to resolve here concern the fact that the translocation breakpoints for chromosome 11 lie far apart, ...
  https://www.omicsonline.org/peer-reviewed/selective-chromatid-segregation-mechanism-explains-the-etiology-of-chromosome-11-translocationassociated-psychotic-disorders-a-rev-28534.html
*  Balanced Rearrangement
There are two primary types of translocations: reciprocal translocations and Robertsonian translocations. A reciprocal ... Genetic disease. Balanced Rearrangement. Chromosome structure abnormalities can be either unbalanced rearrangements or balanced ... Translocations. Translocation is the exchange of chromosome segments, usually between nonhomologous chromosomes. ... Robertsonian translocations lead to a balanced karyotype with only 45 chromosomes. Because acrocentric short arms contain just ...
  https://studentreader.com/B5K5V/balanced-rearrangement/
*  The Role of ATM in Suppression of Lymphomas - Shan Zha
... we propose to elucidate the molecular function of ATM in suppression of oncogenic translocations in developing lymphocytes and ... In this application, we propose to elucidate the molecular function of ATM in suppression of oncogenic translocations in ... Expanding the genetic code by targeted pseudouridylation. *Compound and Strategies for Treating MRSA and VRE ... Molecular characterizations of recurrent translocations in lymphoid malignancies have led to the discovery of key oncogenes (e. ...
  http://grantome.com/grant/NIH/R01-CA158073-04
*  Cytogenetics sub-cluster 89
To understand the genetic basis of its resistance to blast, we developed a population of recombinant inbred lines from a cross ... A Novel Multiplex RT-PCR Assay for the Detection of Four Chromosomal Translocations ... ... Parallel developmental genetic features underlie stickleback gill raker evolution. Glazer Andrew M AM Molecular and Cell ... Preimplantation genetic diagnosis (PGD) for monogenic disorders has the drawback of time and cost associated with tailoring a ...
  http://www.biomedsearch.com/cluster/35/Cytogenetics/sub-89.html
*  WikiGenes - Translocation, Genetic
Associations of Translocation, Genetic with chemical compounds. *CML cells carrying the t(9;22) chromosomal translocation are ... Gene context of Translocation, Genetic. *A t(9;12)(p24;p13) chromosomal translocation in a T cell childhood acute lymphoblastic ... Disease relevance of Translocation, Genetic. *Acute lymphoblastic leukemias carrying a chromosomal translocation involving the ... Anatomical context of Translocation, Genetic. *DNA containing breakpoints of two different t(7;9) chromosomal translocations ...
  https://www.wikigenes.org/e/mesh/e/23250.html
*  Familial Turner syndrome with an X;Y translocation mosaicism: implications for genetic counseling.
We report an unusual case of familial Turner syndrome with mosaicism for a novel X;Y translocation involving Xp ... We report an unusual case of familial Turner syndrome with mosaicism for a novel X;Y translocation involving Xp and Yp. The ... Prenatal diagnosis revealed a female karyotype, with transmission of the maternal translocation with an unexpected different ...
  http://www.biomedsearch.com/nih/Familial-Turner-syndrome-with-translocation/22809487.html
*  Translocations: the genetic rescue paradox | ConservationBytes.com
Translocations: the genetic rescue paradox. 14 01 2013 Harvesting and habitat alteration reduce many populations to just a few ... translocations might elicit outbreeding depression, regardless of whether inbreeding depression is counteracted.Translocations ... Such passive genetic manipulations have become a major tool in conservation biology and they are likely to become more and more ... In translocations, the opposite of outbreeding depression is 'hybrid vigour' (also known as 'heterosis'), that is, when foreign ...
  https://conservationbytes.com/2013/01/14/translocations-genetic-rescue-paradox/?like=1&source=post_flair&_wpnonce=420e8d64d7
*  Translocations and the 'genetic rescue' of bottlenecked populations
... it is essential to realise that genetic interventions in form of reciprocal translocations need to be complemented with other ... To confirm whether 'genetic rescue' through the use of inbred populations can be used in a free-living animal, I repeated the ... The objective of this thesis was to examine both the consequences of severe bottlenecks and the use of translocations to ... Severe bottlenecks are expected to lead to increased inbreeding depression and the loss of genetic diversity, and hence reduce ...
  https://ir.canterbury.ac.nz/handle/10092/7278
*  The genetic stability of a recombinant form of the Lr19 translocation of wheat
... Vermaak, Charmaine (1999) ... Genetic susceptibility to tuberculosis in Africans: A genome-wide scan  Bellamy R.; Beyers N.; McAdam K.P.W.J.; Ruwende C.; ... The genetic structure of Pyrenophora teres, the causal agent of net blotch of barley, was examined in two fields 30 km apart in ... Population genetic structure and demographical history of South African abalone, Haliotis midae, in a conservation context  ...
  http://scholar.sun.ac.za/handle/10019.1/51482
*  Study Comparing Standard Dose and High-dose Imatinib Mesylate in Patients With Chronic Phase Philadelphia Chromosome Positive ...
Translocation, Genetic. Chromosome Aberrations. Pathologic Processes. Imatinib Mesylate. Antineoplastic Agents. Protein Kinase ... Genetic and Rare Diseases Information Center resources: Myeloid Leukemia Chronic Myeloid Leukemia Chronic Myeloproliferative ...
  https://clinicaltrials.gov/show/NCT00171899
*  A Study of Imatinib Versus Nilotinib in Adult Patients With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Chronic...
Translocation, Genetic. Chromosome Aberrations. Pathologic Processes. Imatinib Mesylate. Antineoplastic Agents. Protein Kinase ... Genetic and Rare Diseases Information Center resources: Myeloid Leukemia Chronic Myeloid Leukemia Chronic Myeloproliferative ...
  https://clinicaltrials.gov/show/NCT00471497
*  A Phase 1/2 Study of Ponatinib in Japanese Patients With Chronic Myeloid Leukemia (CML) and Ph+ Acute Lymphoblastic Leukemia ...
Translocation, Genetic. Chromosome Aberrations. Pathologic Processes. Ponatinib. Antineoplastic Agents. Protein Kinase ... Genetic and Rare Diseases Information Center resources: Acute Lymphoblastic Leukemia Myeloid Leukemia Chronic Myeloid Leukemia ... Other measures include mutation testing and molecular genetic assessment. Accrual is expected to take approximately 12 months, ...
  https://clinicaltrials.gov/ct2/show/NCT01667133
*  The importance of genetic considerations for planning translocations in the rare healthland species Boronia rivularis (Rutaceae...
The results also indicate that any compensatory translocation program needs to mimic this genetic substructuring. Largely due ... This study revealed genetic diversity was high in some subpopulations but progressively decreased as plant population density ... A previous study of genetic diversity in B. rivularis found a nearby population to be highly inbred and genetically depauperate ... The large population size and the genetic structuring suggest the nearby population may have arisen from this one and ...
  http://research.usc.edu.au/vital/access/manager/Repository/usc:1464
*  2012, Graduate Research, Assessing the Need for and Impact of Translocation as a Means of Genetic Rescue in a Declining...
Assessing the Need for and Impact of Translocation as a Means of Genetic Rescue in a Declining Population of Sharp-Tailed ... Assessing the Need for and Impact of Translocation..., 2012. Download whole document (PDF) (774.08 KB) ...
  https://scholarly.cmich.edu/cgi-bin/cmuscholarly?a=d&d=CMUGR2012-108.1.27
*  High incidence of t(11;18)(q21;q21) in Helicobacter pylori-negative gastric MALT lymphoma.
Translocation, Genetic*. Treatment Failure. Chemical. Reg. No./Substance: 0/Adaptor Proteins, Signal Transducing; 0/BCL10 ... Translocation-positive gastric MALT lymphomas tend to be aggressive, and patients with such lymphomas might benefit from prompt ... including one case suspicious for a BCL10-involved chromosomal translocation. Our results show that t(11;18)(q21;q21) occurs at ...
  http://www.biomedsearch.com/nih/High-incidence-in-Helicobacter-pylori/12517817.html
*  New recurrent balanced translocations in acute myeloid leukemia and myelodysplastic syndromes: cancer and leukemia group B 8461.
In search of new recurrent balanced translocations, we reviewed t ... Translocation, Genetic*. Transplantation, Autologous. Treatment ... As a result, we identified seven new recurrent balanced translocations in AML or MDS: t(7;11)(q22;p15.5), t(10;11)(q23;p15), t( ... New recurrent balanced translocations in acute myeloid leukemia and myelodysplastic syndromes: cancer and leukemia group B 8461 ... We hope that once the awareness of their existence is increased, some of these translocations may become recognized as novel ...
  http://www.biomedsearch.com/nih/New-recurrent-balanced-translocations-in/23225546.html
*  Burkitt lymphoma facts, information, pictures | Encyclopedia.com articles about Burkitt lymphoma
In addition to translocations of genetic material, Burkitt's lymphoma is also associated with oncogenic viruses-the Epstein- ... It results from a translocation, or exchange, of genetic material between the long arm of human chromosome 8 and the long arm ... Burkitt's lymphoma is associated with a genetic translocation.. QUESTIONS TO ASK THE DOCTOR. *Should I consider bone marrow ... In addition, patients with Burkitt's lymphoma may want to consider genetic counseling because of the role of the C-myc oncogene ...
  http://www.encyclopedia.com/medicine/diseases-and-conditions/pathology/burkitt-lymphoma
*  core binding factor alpha Summary Report | CureHunter
Genetic Translocation (Chromosomal Translocation) 05/01/1995 - "One of the genes that encodes a CBF alpha subunit is AML1, also ... 02/01/1999 - "Both genes involved, translocation ets like gene (or ETV6) on chromosome 12 and acute myeloid leukemia 1 gene (or ... 05/24/2004 - "A common chromosomal translocation in acute myeloid leukemia (AML) involves the AML1 (acute myeloid leukemia 1, ... 05/24/2004 - "A common chromosomal translocation in acute myeloid leukemia (AML) involves the AML1 (acute myeloid leukemia 1, ...
  http://www.curehunter.com/public/keywordSummaryC406688-core-binding-factor-alpha.do
*  Symptoms and causes - Mayo Clinic
Being carriers of the genetic translocation for Down syndrome. Both men and women can pass the genetic translocation for Down ... When balanced translocations are inherited, the mother or father has some rearranged genetic material from chromosome 21 on ... A genetic counselor can help you understand your chances of having a child with Down syndrome. He or she can also explain the ... Translocation Down syndrome can be passed from parent to child. However, only about 3 to 4 percent of children with Down ...
  https://www.mayoclinic.org/diseases-conditions/down-syndrome/symptoms-causes/syc-20355977?footprints=mine&p=1
*  Clinical experience using single nucleotide polymorphism (SNP) arrays for preimplantation genetic diagnosis (PGD) of...
... of chromosomal translocations ... arrays for preimplantation genetic diagnosis (PGD) of ... Clinical experience using single nucleotide polymorphism (SNP) arrays for preimplantation genetic diagnosis (PGD) ...
  https://www.wrh.ox.ac.uk/publications/568016
*  Patent US4755458 - Composition and method for the detection of the presence of a polynucleotide ... - Google Patents
These genetic analyses include, for example, the diagnosis of infections by foreign microbes and the detection of specific ... genetic traits and abnormalities. More specifically, the present invention is related to the detection of the presence of a ... The present invention relates to a wide range of genetic analyses using the technique of nucleic acid hybridization. ... Method of detecting genetic translocations identified with chromosomal abnormalities. US6280952. May 19, 2000. Aug 28, 2001. ...
  http://www.google.com/patents/US4755458?dq=6188988