*  Transcription Factor Brn-3C Summary Report | CureHunter
A POU domain factor that activates neuronal cell GENETIC TRANSCRIPTION of GENES encoding NEUROFILAMENT PROTEINS, alpha ... Mutations in the Brn-3c gene have been associated with DEAFNESS. ... Brn 3c Transcription Factor; Brn-3C, Transcription Factor; ... Transcription Factor Brn 3C; Transcription Factor, Brn-3c; Transcription Factor, Pou4f3; Brn-3c Transcription Factor; Pou4f3 ... Transcription Factors: 20597*POU Domain Factors: 14*Transcription Factor Brn-3*Transcription Factor Brn-3C: 4*human POU4F3 ...
  http://www.curehunter.com/public/keywordSummaryD050821-Transcription-Factor-Brn-3C.do
*  Index by author - January 18, 2012, 32 (3) | Journal of Neuroscience
Combinatorial Expression of Brn3 Transcription Factors in Somatosensory Neurons: Genetic and Morphologic Analysis Tudor ... Combinatorial Expression of Brn3 Transcription Factors in Somatosensory Neurons: Genetic and Morphologic Analysis Tudor ... Combinatorial Expression of Brn3 Transcription Factors in Somatosensory Neurons: Genetic and Morphologic Analysis Tudor ... Combinatorial Expression of Brn3 Transcription Factors in Somatosensory Neurons: Genetic and Morphologic Analysis Tudor ...
  http://www.jneurosci.org/content/32/3.index-by-author
*  004847 - B6;129-Gt(ROSA)26Sor|tm1(cre/ERT)Nat|/J
Combinatorial expression of brn3 transcription factors in somatosensory neurons: genetic and morphologic analysis. J Neurosci ... Dynamic expression of transcription factor Brn3b during mouse cranial nerve development. J Comp Neurol 524(5):1033-61. PubMed: ... Distinct roles of transcription factors brn3a and brn3b in controlling the development, morphology, and function of retinal ... The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation. Immunity 35(6):871-82. PubMed: ...
  https://www.jax.org/strain/004847
*  Faculty Profile - New York State Center of Excellence in Bioinformatics & Life Sciences - University at Buffalo
Genetic interactions between Brn3 transcription factors in retinal ganglion cell type specification. PLoS One. 2013; 8(10). ... Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic ... Function of Onecut transcription factors in retinal development and vision. SUNY Research Foundation. Role: Principal ... Wu F, Kaczynski TJ, Sethuramanujam S, Li R, Jain V, Slaughter M, Mu X. Two transcription factors, Pou4f2 and Isl1, are ...
  https://www.buffalo.edu/bioinformatics/resources/faculty/profile.html?ubit=xmu
*  BRN-3 - Wikipedia
Transcription Factor Brn-3 at the US National Library of Medicine Medical Subject Headings (MeSH). ... BRN-3 is a group of related transcription factors in the POU family. There are three BRN-3 proteins encoded by the following ... "The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion ...
  https://en.wikipedia.org/wiki/BRN-3
*  Frontiers | Non-image Forming Light Detection by Melanopsin, Rhodopsin, and Long-Middlewave (L/W) Cone Opsin in the...
2012). Whole number, distribution and co-expression of brn3 transcription factors in retinal ganglion cells of adult albino and ... Jain, V., Ravindran, E., and Dhingra, N. K. (2012). Differential expression of Brn3 transcription factors in intrinsically ... of the central projections are melanopsin expressing RGCs while the remaining RGCs express the transcription factor Brn3a and ... Using the calculated Abercrombie correction factor [T/T+h, where T = 12 μm, nuclear average (h) = 8.69 μm] of 0.57, the total ...
  https://www.frontiersin.org/articles/10.3389/fnana.2016.00061/full
*  Plus it
1994) The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the ... Acj6 is a class IV POU domain transcription factor homologous to members of the vertebrate Brn3 family (Treacy et al., 1991) ... The lz gene encodes a Zn finger transcription factor important for the development of eyes (Daga et al., 1996; Flores et al., ... The principal conclusion of this study is that theDrosophila class IV POU domain transcription factor Acj6 is required for ...
  http://www.jneurosci.org/content/22/13/5291
*  Retinal Circuit Development & Genetics Unit | National Eye Institute
Genetic Interactions between Brn3 Transcription Factors in Retinal Ganglion Cell Type Specification. PLoS One. 2013 Oct 8;8(10 ... Badea TC, Williams J, Smallwood P, Shi M, Motajo O, Nathans J. Combinatorial expression of Brn3 transcription factors in ... Dynamic expression of transcription factor Brn3b during mouse cranial nerve development. J Comp Neurol. 2015 Sep 10. ... Badea TC, Cahill H, Ecker J, Hattar S, Nathans J. Distinct roles of transcription factors brn3a and brn3b in controlling the ...
  https://nei.nih.gov/intramural/retinal_circuit
*  Multiple influences on the migration of precerebellar neurons in the caudal medulla | Development
1B,E-G) whereas Brn3.2, which encodes a POU domain transcription factor (Turner et al., 1994), is expressed in the olivary ... Turner, E. E., Jenne, K. J. and Rosenfeld, M. G. (1994). Brn-3.2: A Brn-3-related transcription factor with distinctive central ... Later on, Brn 3.2 expression persisted only in the ION. TAG-1 and Brn3.2 were used as markers of the two migrations in ... 2H). In transverse sections of the explants, the Brn 3.2+ ION was located more ventrally than in vivo and was fused on the ...
  http://dev.biologists.org/content/129/2/297
*  Distinct developmental programs require different levels of Bmp signaling during mouse retinal development | Development
Liu, W., Mo, Z. and Xiang, M. (2001). The Ath5 proneural genes function upstream of Brn3 POU domain transcription factor genes ... Ectopic expression of Bmp4 in the embryonic chick retina leads to the upregulation of the dorsal transcription factor, Tbx5, ... By contrast, the expression of retinal anterior homeobox gene Rx and LIM domain-containing transcription factor gene Lhx2, both ... 6E). A potential target gene of Math5 is Brn3b, which encodes a POU-homeodomain-containing transcription factor required for ...
  http://dev.biologists.org/content/132/5/913
*  Volume 2 - GTMB: Gene Therapy & Molecular Biology
Although these factors are closely related to one another, they have distinct functions. Thus, Brn-3a activates the expression ... Abstract: The zinc-finger transcription factor EGR-1 provides protection from G1 phase growth arrest. We present here evidence ... Brn-3a, Brn-3b and Brn-3c, all of which are expressed in distinct but overlapping groups of neuronal cells in the developing ... Thus Brn-3a may be of potential use in a gene therapy approach to human neurological diseases which involve either a failure of ...
  http://gtmb.org/?vol=2
*  can cymbalta afvallen ultrasound
Role Cymbalta common uses transcription factors Brn-3. Cybmalta Recombination between an OPN1MW in afvaleln three gene array ... Pharmacol Commun 1992; 2 57-62.Levy-Nissenbaum, E. With PSR, the risk factors for vitreous bleeding are cymbalta afvallen SC ... J.Dezawa, M. 2. 3 per 100 000 person-years in the immunocompetent population. In addition to the developmental increase in the ... 3 1 3 Figure 5 coma cymbalta afvallen of electrically induced convulsions in mice (n8). ...
  http://politvolga.ru/cheap-drugs-in-india/cymbalta-afvallen.html
*  New Jersey Commission Science and Technology Grants - Stem Cell Institute of New Jersey
... him to achieve a comprehensive understanding of the crucial functions of the Brn3 subfamily of POU domain transcription factors ... epidermal growth factor (EGF), insulin-like growth factor (IGF) and fibroblast growth factor (FGF)) act singly or in ... His laboratory employs molecular genetic approaches in animal models to identify and study transcription factors that are ... Xiang's laboratory utilizes two general approaches to understand the biological roles that a transcription factor gene plays ...
  http://rwjms.umdnj.edu/scinj/research/Compendium.html
*  Brn3a as a Marker of Retinal Ganglion Cells: Qualitative and Quantitative Time Course Studies in Naïve and Optic Nerve-Injured...
The Brn-3a transcription factor. Int J Biochem Cell Biol. 1998;30:1153-1157. [CrossRef] [PubMed] ... Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to ... The Brn3 family of POU-domain transcription factors has been shown to play important roles in differentiation, survival, and ... The Brn-3a transcription factor inhibits the pro-apoptotic effect of p53 and enhances cell cycle arrest by differentially ...
  https://iovs.arvojournals.org/article.aspx?articleid=2186188
*  Methods of Retinal Ganglion Cell Differentiation From Pluripotent Stem Cells | TVST | ARVO Journals
Pan L et al . Functional equivalence of Brn3 POU-domain transcription factors in mouse retinal neurogenesis. Development . 2005 ... Badea TC et al . Combinatorial expression of Brn3 transcription factors in somatosensory neurons: genetic and morphologic ... During development of the embryo, eye field transcription factors (EFTFs) specify development of the eye. 22 The eye field is ... Zuber ME et al . Specification of the vertebrate eye by a network of eye field transcription factors. Development . 2003; 130: ...
  http://tvst.arvojournals.org/article.aspx?articleid=2120948
*  Pro-Photoreceptor Activity of Chick neurogenin1 | IOVS | ARVO Journals
Liu W Mo Z Xiang M . The Ath5 proneural genes function upstream of Brn3 POU domain transcription factor genes to promote ... Brown NL Kanekar S Vetter ML Tucker PK Gemza DL Glaser T . Math5 encodes a murine basic helix-loop-helix transcription factor ... Pennesi ME Cho JH Yang Z . BETA2/NeuroD1 null mice: a new model for transcription factor-dependent photoreceptor degeneration. ... This could result from confounding factors in the retina, including bHLH factors cross-regulating one another through networks ...
  http://iovs.arvojournals.org/article.aspx?articleid=2184892
*  Proliferation-associated POU4F2/Brn-3b transcription factor expression is regulated by oestrogen through ERα and growth factors...
In cancer cells, elevated transcription factor-related Brn-3a regulator isolated from brain cDNA (Brn-3b) transcription factor ... is referred to as Brn-3b because of homology in the DNA binding domain to the related Brn-3a transcription factor. Brn-3b is ... transcription factor-related Brn-3a regulator isolated from brain cDNA. BSX-Brn-3b: promoter containing BstX1/Stu1/Xho1 ... Proliferation-associated POU4F2/Brn-3b transcription factor expression is regulated by oestrogen through ERα and growth factors ...
  https://breast-cancer-research.biomedcentral.com/articles/10.1186/bcr2809
*  Functional and Cellular Responses in a Novel Rodent Model of Anterior Ischemic Optic Neuropathy | IOVS | ARVO Journals
1999) POU domain factor Brn-3b is essential for retinal ganglion cell differentiation and survival but not for initial cell ... 1995) Fos: an immediate-early transcription factor in neurons J Neurobiol 26,403-412 [CrossRef] [PubMed] ... brn 3.2; accession number S68377) and human brn 3b (U06233) homologues. Brn 3.2 oligonucleotide primers were prepared from ... Brn 3.2 expression in (A) control retinas. Brn 3.2 signal was limited to the RGC nuclei (arrows); (B) RGCs 3 days after rAION ...
  https://iovs.arvojournals.org/article.aspx?articleid=2182114
*  Jeremy Nathans | Hopkins BCMB
2012) Combinatorial expression of Brn3 transcription factors in somatosensory neurons: genetic and morphologic analysis. ... eLife 3:e02444.. Wu, H., Luo, J, Yu, H., Rattner, A., Mo, A., Smallwood, P.M., Erlanger, B., Wheelan, S.J., and Nathans, J. ( ... In one set of experiments we created a variety of knock-in alleles in which a pair of loxP sites flank the coding region and 3 ... untranslated region (UTR) of a gene of interest, with a reporter gene inserted distal to the 3'-most loxP site. When the ...
  http://bcmb.bs.jhmi.edu/people/faculty/jeremy-nathans
*  Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to...
Transcription Factor Brn-3A, Transcription Factors, Tumor Suppressor Protein p53, bcl-2-Associated X Protein. ... Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to ... Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to ... Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to ...
  http://discovery.ucl.ac.uk/36939/
*  Stage-specific up-regulation of Brn3a, TrkA, and Bcl-xL | Open-i
Transcription Factor Brn-3A. *Transcription, Genetic. *Two-Hybrid System Techniques. *Up-Regulation ... The Pit1-Oct1-Unc86 domain (POU domain) transcription factor Brn3a controls sensory neuron survival by regulating the ... The Pit1-Oct1-Unc86 domain (POU domain) transcription factor Brn3a controls sensory neuron survival by regulating the ... HIPK2 interacts with Brn3a, promotes Brn3a binding to DNA, but suppresses Brn3a-dependent transcription of brn3a, trkA, and bcl ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2172556_200406131f6&req=4
*  POU4F1 - Wikipedia
Budhram-Mahadeo V, Parker M, Latchman DS (Feb 1998). "POU transcription factors Brn-3a and Brn-3b interact with the estrogen ... Budhram-Mahadeo V, Parker M, Latchman DS (Feb 1998). "POU transcription factors Brn-3a and Brn-3b interact with the estrogen ... interacts with the Brn-3a POU transcription factor and inhibits its ability to activate transcription". Cancer Biology & ... interacts with the Brn-3a POU transcription factor and inhibits its ability to activate transcription". Cancer Biology & ...
  https://en.wikipedia.org/wiki/POU4F1
*  Pou4f2 - POU domain, class 4, transcription factor 2 - Mus musculus (Mouse) - Pou4f2 gene & protein
Cooperates with the transcription factor ISL1 to achieve RGC fate specification in the developing retina (PubMed:25775587). ... A-3' in promoter of target genes (PubMed:7904822, PubMed:8290353, PubMed:7935408, PubMed:9111308, PubMed:10414983, PubMed: ... "Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development.". Erkman L., McEvilly R.J., Luo L. ... "Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development.". Erkman L., McEvilly R.J., Luo L. ...
  http://www.uniprot.org/uniprot/Q63934
*  Elevated expression of the Brn-3a and Brn-3b transcription factors in systemic lupus erythematosus correlates with antibodies...
Serum antibodies to the Brn-3a and Brn-3b transcription factors were measured by enzyme-linked immunosorbent assay. Levels of ... Elevated expression of the Brn-3a and Brn-3b transcription factors in systemic lupus erythematosus correlates with antibodies ... Elevated expression of the Brn-3a and Brn-3b transcription factors in systemic lupus erythematosus correlates with antibodies ... Elevated expression of the Brn-3a and Brn-3b transcription factors in systemic lupus erythematosus correlates with antibodies ...
  http://discovery.ucl.ac.uk/40235/
*  Proposed model for Brn3a and HIPK2 in transcriptional c | Open-i
Transcription Factor Brn-3A. *Transcription, Genetic. *Two-Hybrid System Techniques. *Up-Regulation ... The Pit1-Oct1-Unc86 domain (POU domain) transcription factor Brn3a controls sensory neuron survival by regulating the ... The Pit1-Oct1-Unc86 domain (POU domain) transcription factor Brn3a controls sensory neuron survival by regulating the ... HIPK2 interacts with Brn3a, promotes Brn3a binding to DNA, but suppresses Brn3a-dependent transcription of brn3a, trkA, and bcl ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2172556_200406131f8&req=4