Activator protein Transcription factor Hess J, Angel P, Schorpp-Kistner M (December 2004). "AP-1 subunits: quarrel and harmony ... "Transcription factor decoy for activator protein-1 (AP-1) inhibits high glucose- and angiotensin II-induced type 1 plasminogen ... Bossy-Wetzel E, Bakiri L, Yaniv M (April 1997). "Induction of apoptosis by the transcription factor c-Jun". The EMBO Journal. ... Lee W, Haslinger A, Karin M, Tjian R (January 1987). "Activation of transcription by two factors that bind promoter and ...
... is an RNA-binding protein, which can both stabilize and destabilize the transcripts of several cancer-related genes. Since ... The AU-rich element RNA-binding protein 1 (AUF1) ... AUF1 targeting the transcription factor ZEB1 and the protein ... The activation of such process is under the control of several transcription factors, such as ZEB1 and TWIST1 (refs 9,10,11). ... Puisieux, A., Brabletz, T. & Caramel, J.Oncogenic roles of EMT-inducing transcription factors. Nat. Cell Biol. 16, 488-494 ( ...
... redox-sensitive transcription factor; JA, jasmonic acid; MAPK, mitogen-activated protein kinase; NADP, oxidized nicotinamide ... redox-sensitive transcription factor; JA, jasmonic acid; MAPK, mitogen-activated protein kinase; NADP, oxidized nicotinamide ... Wang, F.; Zhu, H.; Chen, D.; Li, Z.; Peng, R.; Yao, Q. A grape bHLH transcription factor gene, VvbHLH1, increases the ... Other Abiotic Factors. Other abiotic factors like temperature, nanoparticles, and pesticides also stimulate the endogenous ...
Tumor necrosis factor-alpha inhibits surfactant protein C gene transcription.﻽. Bachurski CJ, Pryhuber GS, Glasser SW, Kelly SE ... Acute tumor necrosis factor-alpha-induced liver injury in the absence of tumor necrosis factor receptor-associated factor 1 ... Tumor necrosis factor-alpha decreases surfactant protein B mRNA in murine lung.﻽. Pryhuber GS, Bachurski C, Hirsch R, Bacon A, ... Effects of TNF-alpha and phorbol ester on human surfactant protein and MnSOD gene transcription in vitro.﻽. Whitsett JA, Clark ...
EGR2 is a transcription factor linked to Charcot-Marie-Tooth disease type 1D (CMT1D). ... Findings on cerebrospinal fluid (CSF) analysis are usually normal in CMT, but protein is often high in DSS; protein was high in ... Mutations in structural myelin genes or the transcription factors responsible for their expression lead to demyelination (ie, ... Mutations in the zinc-finger domain containing transcription factor EGR2 were linked to CMT1D and CHN. ...
EGR2 is a transcription factor linked to Charcot-Marie-Tooth disease type 1D (CMT1D). ... Findings on cerebrospinal fluid (CSF) analysis are usually normal in CMT, but protein is often high in DSS; protein was high in ... Mutations in structural myelin genes or the transcription factors responsible for their expression lead to demyelination (ie, ... Mutations in the zinc-finger domain containing transcription factor EGR2 were linked to CMT1D and CHN. ...
... activating transcription factor 3 (ATF3; n = 7), family with sequence similarity, member A (FAM71A; n = 2), tachykinin receptor ... Electrophoretic mobility shift assays detected allele-dependent nuclear protein binding in A549 cells for 8 of 21 variants. In ... Asthma; Occupational asthma; Genetic factors; Genes; Diisocyanates; Occupational exposure; Genetic predisposition; Bioassays; ... and zinc finger and BTB domain-containing protein 16 (ZBTB16; n = 1). ...
Transcription factors have crucial roles in stem cell biology and differentiation. Research in these fields has broad ... Transcription factors are proteins that regulate the transcription of genes, or the production of mRNA from DNA. Their unique ... STAT3 protein belongs to a group of intracellular transcription factors that mediate a variety of functions such as cellular ... Pax6 is a transcription factor present during embryonic development. The encoded protein contains two different binding sites ...
General protein information Go to the top of the page Help Preferred Names. myelin transcription factor 1-like protein. Names. ... DUF812; Protein of unknown function (DUF812). pfam08474. Location:619 → 870. MYT1; Myelin transcription factor 1. ... DUF812; Protein of unknown function (DUF812). pfam08474. Location:621 → 872. MYT1; Myelin transcription factor 1. ... mRNA and Protein(s) * XM_011510326.2 → XP_011508628.1 myelin transcription factor 1-like protein isoform X5 ...
The WT1 protein is a transcription factor predominantly expressed in the embryonic kidneys and gonads. Exons 1-6 of the WT1 ... The WT1 Wilms tumor gene product: a developmentally regulated transcription factor in the kidney that functions as a tumor ... DNA binding capacity of the WT1 protein is abolished by Denys-Drash syndrome WT1 point mutations. Hum Mol Genet. 1995 Mar. 4(3 ... The WT1 protein mediates the mesenchymal-epithelial transition and differentiation during morphogenesis of the kidney and gonad ...
Abnormal nephron development associated with a frameshift mutation in the transcription factor hepatocyte nuclear factor-1 beta ... This gene product is an integral membrane protein that is a G-protein coupled 7-transmembrane receptor, its predominant ... Variant of transcription factor 7-like 2 (TCF7L2) gene and the risk of type 2 diabetes in large cohorts of U.S. women and men. ... Variant of Transcription Factor 7-Like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat. Genet., 38: 320-323.. CrossRef ...
Without Transcription Factor Sp7, Teeth Dont Develop. A lack of the transcription factor Specificity protein 7 (Sp7) ...
The site-specific transcription factors. Transcription mediator interplays with the transcription activator proteins and the ... 2. Transcription factors (TFs) in mammalian cells. Transcription factors are divided into two groups. First, the general TFs ( ... 2.2.2. Helix-turn-helix (HTH) proteins. The ETS, FOX, IRF, HOX, HSF, POU, and PAX proteins belong to the HTH protein group. The ... are the primary protein factors that are required for the initiation of transcription from the TATA box (or TATA element), then ...
Transcription factor p65/Interferon regulatory factor 7/Interferon regulatory factor 3 fusion protein. C [auth A]. 540. Homo ... These factors bind cooperatively to the IFN-beta enhancer and recruit coactivators and chromatin-remodeling proteins to the IFN ... Paucity of local protein-protein contacts suggests that cooperative occupancy of the enhancer comes from both binding-induced ... Nuclear factor NF-kappa-B p105 subunit. D [auth B]. 314. Homo sapiens. Mutation(s): 0 Gene Names: NFKB1. ...
protein coding gene. Chr13:100154502-100244524 (-). 129S1/SvImJ MGP_129S1SvImJ_G0020879. protein coding gene. Chr13:101843039- ... protein coding gene. Chr13:100081628-100170895 (-). CBA/J MGP_CBAJ_G0020582. protein coding gene. Chr13:109044673-109139388 (-) ... protein coding gene. Chr13:100917343-101006671 (-). BALB/cJ MGP_BALBcJ_G0020831. protein coding gene. Chr13:98632830-98719306 ... protein coding gene. Chr13:100640129-100728065 (-). C57BL/6NJ MGP_C57BL6NJ_G0021265. protein coding gene. Chr13:104868192- ...
The transcription repressor NmrA is subject to proteolysis by three Aspergillus nidulans proteases. Protein Science 2010, 19(7 ... Analysis of the Recognition of the Negative Regulator NmrA and DNA by the Zinc Finger from the GATA-Type Transcription Factor ... Protein Science 2004, 13(12), 3127-3138. * Lamb HK, Leslie K, Dodds AL, Nutley M, Cooper A, Johnson C, Thompson P, Stammers DK ... Proteins: Structure, Function and Genetics 2006, 64(1), 111-123. * Lamb HK, Ren J, Park A, Johnson C, Leslie K, Cocklin S, ...
The transcription cofactor RIP140 (receptor-interacting protein of 140 kDa), also known as NRIP1 (nuclear receptor-interacting ... C) Schematic drawing of the human APC gene promoter region showing experimentally characterized transcription factor-binding ... Multiple domains of the receptor-interacting protein 140 contribute to transcription inhibition. Nucleic Acids Res. 2004;32(6): ... This suggests that other transcription factors controlling expression of the Axin2 gene are positively regulated by RIP140. ...
Class b: All beta proteins [48724] (93 folds). *. Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f ... Protein Cytochrome f, large domain [49443] (3 species). *. Species Chlamydomonas reinhardtii [TaxId:3055] [49445] (5 PDB ... SCOP: Structural Classification of Proteins and ASTRAL. Release 1.55 (July 2001) Copyright © 1994-2009 The SCOP and Astral ... Superfamily b.2.6: Cytochrome f, large domain [49441] (1 family) *. Family b.2.6.1: Cytochrome f, large domain [49442] (1 ...
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a). Mol Cell ... and transcription factors (e.g., β-catenin and nuclear factor-κB)[10,22,23]. Moreover, excessive SGK1 expression is involved in ... Eylenstein A, Schmidt S, Gu S, Yang W, Schmid E, Schmidt EM, Alesutan I, Szteyn K, Regel I, Shumilina E. Transcription factor ... In the first pathway, SGK1 phosphorylates and inhibits pro-apoptotic transcription factors, such as Forkheadbox O3a (FOXO3a) ...
Transcription Factor AP-2. Li Q, Löhr CV, Dashwood RH. 2009. Activator protein 2alpha suppresses intestinal tumorigenesis in ... Transcription Factor RelA. Wang R, Dashwood W-M, Nian H, Löhr CV, Fischer KA, Tsuchiya N, Nakagama H, Ashktorab H, Dashwood RH ... Transcription Factor AP-1. Li Q, Dashwood W-M, Zhong X, Al-Fageeh M, Dashwood RH. 2004. Cloning of the rat beta-catenin gene ( ... Transcription Factors. Li Q, Dashwood W-M, Zhong X, Al-Fageeh M, Dashwood RH. 2004. Cloning of the rat beta-catenin gene ( ...
Role of specificity protein transcription factors in estrogen-induced gene expression in MCF-7 breast cancer cells. J Mol ... by calmodulin kinase IV-dependent activation of a nuclear factor kappa B/CCAAT-binding transcription factor-1 complex. Mol ... Role of SP transcription factors in hormone-dependent modulation of genes in MCF-7 breast cancer cells: microarray and RNA ... Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathways. J Mol ...
Finkelhor, which in turn interact with proteins of the basal transcription factor com- plex. 4581 aData were compiled from the ... These factors are discussed in the following sections. 39 1. The gravity of the stellar material pulls on all the other stellar ... RNA-protein complexes were investigated early on by digestion with nucleases (such as nuclease SI or RNase Vl). Cheney and ... It is likely that similar epitopes are present forex accept paypal the spore coat proteins of many microsporidia, so that ...
The WT1 protein is a transcription factor predominantly expressed in the embryonic kidneys and gonads. Exons 1-6 of the WT1 ... The WT1 Wilms tumor gene product: a developmentally regulated transcription factor in the kidney that functions as a tumor ... DNA binding capacity of the WT1 protein is abolished by Denys-Drash syndrome WT1 point mutations. Hum Mol Genet. 1995 Mar. 4(3 ... The WT1 protein mediates the mesenchymal-epithelial transition and differentiation during morphogenesis of the kidney and gonad ...
Protein Family Unit Price 250488 C-phycocyanin Antibody. Rabbit Polyclonal Antibody Rabbit Ig Bact E, IHC, WB Photosynthesis ... Transcription Factors (343) *Translation Factors (29) *Transporters (210) *Ubiquitins (46) Products. *Antibodies ... Proteins, Transporters 0.1 mg $323.00 250391 Atrazine (1F9) Antibody. Mouse Monoclonal Antibody Mouse IgG2a/k Other E ...
Transcription Factors / metabolism * Xenograft Model Antitumor Assays Substances * 3-(8-amino-1-(2-phenylquinolin-7-yl)imidazo( ... Chromosomal Proteins, Non-Histone / genetics * Chromosomal Proteins, Non-Histone / metabolism * Cyclin-Dependent Kinase ... Stefan Prekovic # 1 , Karianne Schuurman # 2 , Isabel Mayayo-Peralta 2 , Anna G Manjón 3 , Mark Buijs 2 , Selçuk Yavuz 2 , Max ... and activation of growth factor survival signalling accompanied by vulnerability to inhibitors. GR-induced dormancy is ...
... using activating transcription factor-2 (ATF-2) as the bait (22). Structurally, JDP2 proteins have three parts: (a) an NH2- ... other Jun proteins (23), and activating transcription factor-2 (ATF-2; reference 22). ... The predicted protein was found to be a mouse homologue of Jun dimerization protein 2 (JDP2), a member of the AP-1 family of ... Abbreviations used in this paper: EGFP, enhanced green fluorescent protein; JDP2, Jun dimerization protein 2; JNK, c-Jun NH2- ...
All factors were upregulated in COV434 cells exposed to Cd, and the expression of the p-eIF2α protein was downregulated in sh- ... The chromatin associated transcription factor HMGA2 is a downstream target of let-7 miRNAs and binds to chromatin to regulate ... We found that mRNA and protein levels of all factors were upregulated in each cadmium-dose group, except for BIP mRNA ... Heparin-binding epidermal growth factor (EGF)-like growth factor (HBEGF) is expressed in the embryo and uterus at the ...
... factors bind closed chromatin to enhance accessibility for other transcription factors and epigenetic-regulatory proteins ... This subset of transcription factors, known as pioneer transcription factors (PTFs), possess the ability to engage closed ... identified the transcription factor LEAFY as a PTF with the ability to bind nucleosome-occupied[6] DNA, displace H1 linker ... The transcription factors Oct4, Sox2, and Klf4 were found to trigger endogenous expression of pluripotent genes[2] and were ...